Papers - Okano, Hideyuki

RNA binding protein Musashi1 is expressed in sertoli cells in the rat testis from fetal life to adulthood

Saunders PTK, Maguire SM, Macpherson S, Fenelon MC, Sakakibara Shin-ichi, Okano Hideyuki

Biology of Reproduction 66 ( 6 ) 500-507 2002.02

Research paper (scientific journal), Joint Work

神経幹細胞とその医療応用について

Kanemura Yonehiro，Hara Masayuki，Okano Hideyuki

生体材料 20 ( 2 ) 39-45 2002.02

Research paper (scientific journal), Joint Work

幹細胞システムを用いた神経再生の試み

Okano Hideyuki

日本臨床分子医学会記録 38   25 2002.02

Research paper (scientific journal), Single Work

神経幹細胞

Shibata Shinsuke，Okano Hideyuki

分子細胞治療学 1 ( 1 ) 132-133 2002.02

Research paper (scientific journal), Joint Work

神経幹細胞：その同定・分離法の開発と移植による神経機能回復の試み

Okano Hideyuki

日本老年医学会雑誌 39 ( 1 ) 44-47 2002.01

Research paper (scientific journal), Single Work

神経幹細胞の同定法とその応用

Kanemura Yonehiro，Okano Hideyuki

CLINICAL NEUROSCIENCE 別冊 20 ( 1 ) 14-19 2002.01

Research paper (scientific journal), Joint Work

神経幹細胞の同定・分離法の確立と神経再生への挑戦

Okano Hideyuki

生化学 74 ( 1 ) 17-26 2002.01

Research paper (scientific journal), Single Work

Identification of Musashi1-positive cells in human normal and neoplastic neuroepithelial tissues by immunohistochemical methods.

Kanemura Yonehiro, Sakakibara Shin ichi, Okano Hideyuki

Methods in molecular biology (Clifton, N.J.) 198   273 - 281 2002

ISSN  1064-3745

特集―中枢神経系の再生に挑む；損傷脊髄への神経幹細胞移植

Nakamura Masaya, Toyama Yoshiaki, Okano Hiroyuki

実験医学 20 ( 9 ) 1301-1306 2002

Research paper (scientific journal), Joint Work

損傷脊髄内サイトカイン・神経栄養因子mRNAの発現の変化

Nakamura Masaya, Okano Hiroyuki, Chiba Kazuhiro, Bregman Bs, Toyama Yoshiaki

日本パラプレジア医学会誌 15 ( 1 ) 126-127 2002

Research paper (scientific journal), Joint Work

神経疾患における再生医療

'松本有史,　岡野栄之'

日本内科学会雑誌 92 ( 12 ) 110-116 2003.12

Research paper (scientific journal), Joint Work

幹細胞システムを用いた中枢神経の再生医学

'飯島崇利,　岡野栄之'

神経研究の進歩 47 ( 6 ) 841-849 2003.12

Research paper (scientific journal), Single Work

Growth and differentiation potential of main- and side-population cells derived from murine skeletal muscle.

'Tamaki Tsturo, Akatsuka Akira, Okada Yoshinori, Matsuzaki Yumi, Okano Hideyuki, Kimura Minoru'

Experimental Cell Research 291 ( 1 ) 83 - 90 2003.11

Research paper (scientific journal), Joint Work, Accepted

Regeneration of central nervous system

Okano Hideyuki, Yoshizaki Takahito, Okada Seiji

Clinical Neurology 43 ( 11 ) 824 - 826 2003.11

ISSN  0009-918X

　View Summary

<p>It had been long believed that our adult mammalian central nervous system (CNS) does not regenerate after damage due to injuries or degenerative diseases, as Santiago Ramóny Cajal had indicated long time ago. Today, however, CNS came to be recognized as an important target of so called "regenerative medicine". We have been proposing that regeneration of CNS does include the following three concepts: i) re-growth of the damaged neuronal axons, ii) replenishment of lost neural (or neuronal) cells and iii) recovery of lost neural functions. Here, we would like to emphasize that to recapitulate normal neural development is an essential strategy for CNS-regeneration. In this review, we would like to take Parkinson's disease and spinal cord injury as examples to discuss actual strategy aiming for CNS-regeneration.</p>

神経幹細胞の治療への応用

'安達一英,　澤本和延,　岡野栄之'

実験医学 21 ( 17 ) 2440-2445 2003.11

Research paper (scientific journal), Single Work

Symposium 4

Okano Hideyuki, Mizusawa Hidehiro

Clinical Neurology 43 ( 11 ) 823 2003.11

ISSN  0009-918X

'Origin of higher affinity to RNA of the N-terminal RNA-binding domain than that of the C-terminal one of a mouse neural protein, musashi1, as revealed by comparison of their structures, modes of interaction, surface electrostatic potentials, and backbone dynamics.'

'Miyanoiri Youhei, Kobayashi Hisanori, Imai Takao, Watanabe Michinao, Nagata Takashi, Uesugi Seiichi, Okano Hideyuki<, Katahira Masato'

Journal of Biological Chemistry 278 ( 42 ) 41309-41315 2003.10

Research paper (scientific journal), Joint Work, Accepted

F3/Contactin acts as a functional ligand for Notch during oligodendrocyte maturation.

'Hu Qi-Dong, Ang Beng-Ti, Karsak Meliha, Hu Wei-Ping, Cui Xiao-Ying, Duka Tanya, Takeda Yasuo, Chia Wency, Sankar Natesan, Ng Yee-Kong, Ling Eng-Ang, Maciag Thomas, Small Deena, Trifonova Radianna, Kopan Raphael, Okano Hideyuki, Nakafuku Masato, Chiba Shigeru, Hirai Hisamaru, Aster C.Jon, Schachner Melitta, Pallen J.Catherine, Watanabe Kazutada, Xiao Zhi-Cheng'

Cell 115   163-175 2003.10

Research paper (scientific journal), Joint Work, Accepted

精神科領域の用語解説・神経幹細胞

'山下徹,　澤本和延,　岡野栄之'

分子精神医学 3 ( 4 ) 342-344 2003.10

Research paper (scientific journal), Single Work

Distinct expression patterns of splicing isoforms of mNumb in the endocrine lineage of developing pancreas

'Yoshida Tetsu, Tokunaga Akinori, Nakao Keiko, Okano Hideyuki'

Differentiation 71/8   486-495 2003.10

Research paper (scientific journal), Joint Work, Accepted