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Papers - Oguma, Yuko

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Drug burden of polypharmacy and anticholinergic/sedative drugs and physical/cognitive/mental related outcomes of the community-dwelling elderly people: The Kawasaki well-being …

R Asano, A Tanaka, Y Arai, T Hirata, Y Abe, Y Oguma, H Urushihara

PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 28, 293-293 2019

Joint Work

Classification of body components and activity patterns by data mining of health care data.

Shunichi Nomura, Michiko Watanabe, Yuko Oguma

Oukan (Transdisciplinary Federation of Science and Technology) 13 ( 1 ) 15 - 22 2019

Research paper (scientific journal), Joint Work, ISSN 1881-7610

Healthcare data is rapidly increasing as healthcare smart devices are developed. However, statistical analysis of healthcare big data is difficult due to heterogeneity in data quality and missing data. For such data, data mining methods such as clustering and dimension reduction may be useful as their preliminary analysis. In this paper, we show two illustrative applications; one is a principal component analysis of body composition data and the other is a latent topic analysis of hourly step-count dataset recorded by physical activity monitors. From those analyses, we proposed independent indices of body size and hidden obesity and extracted some diurnal patterns in ambulatory activities.

Effects of polypharmacy and anticholinergic/sedative drugs on the physical/cognitive/mental related outcomes of community-dwelling elderly people: The Kawasaki Wellbeing Project

A Tanaka, Y Arai, T Hirata, Y Abe, Y Oguma, H Urushihara

Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 56 (4), 504-515 (The Japan Geriatrics Society) 56 ( 4 ) 504 - 515 2019

ISSN 03009173

Aim: To assess the burdens of polypharmacy and the drug burden index in community-dwelling elder people.Methods: The survey was conducted on 396 participants who participated in The Kawasaki Wellbeing Project from March to December 2017. We investigated the associations between the drug burden and the physical/cognitive/mental outcomes. The drug burden was determined by calculating the number of medications and the drug burden index (DBI) based on the use of anticholinergic and sedative drugs. A multivariate regression analysis was conducted for the outcome measures ADL, IADL, MMSE, J-CHS, and EQ5D5L after adjusting for the sex, age, number of diseases, education level, smoking history, and alcohol history.Results: A total of 389 subjects were analyzed, the mean age of the population was 86 years old, and 187 people (48%) were male. Polypharmacy was reported in 243 people (62%), and DBI exposure was reported for 142 people (36.5%). We found that this population was physically healthy, with a median ADL of 100, and had high quality of life, with a median EQ5D5L of 0.895. Polypharmacy was found to be related to the J-CHS (β: 0.04) and EQ5D5L (−0.01). The DBI was also related to the EQ5D5L (−0.04).Conclusion: These results showed that even though this population was healthier than the general Japanese elderly population, the drug burden of polypharmacy and high dosages of anticholinergic/sedative drugs exerted significant negative effects on frailty and the quality of life. Additional research should be conducted to investigate the long-term effects of polypharmacy and anticholinergic/sedative drugs on elderly people.

健康長寿社会における身体活動と健康ー「ふじさわプラス・テン」の取り組みを通してー

小熊祐子, 齋藤義信

予防医学 60 21 - 25 2019

健康長寿社会における健康支援-アクティブシニアを目指して健康長寿社会における身体活動と健康-「ふじさわプラス・テン」の取り組みを通して

Y OGUMA, Y SAITO

予防医学, 21-25 2019

Population-based approaches to promote physical activity: the Fujisawa +10 project

SAITO Yoshinobu, TAJIMA Takayuki, SHIBA Chisato, OGUMA Yuko

Japanese Journal of Health Education and Promotion (JAPANESE SOCIETY OF HEALTH EDUCATION AND PROMOTION) 27 ( 1 ) 71 - 81 2019

Accepted, ISSN 1340-2560

Objective: We introduced the physical activity promotion project "Fujisawa +10" and aimed to provide reference information regarding evaluation methods and research findings translating to health education and promotion.Contents: We conducted a community-wide intervention to promote physical activity based on the Japanese physical activity guideline (Active Guide) in cooperation with Fujisawa city. The intervention's key message was "Plus Ten (+10: be active for 10 more minutes than now). We implemented this project in 4 districts for 2 years from 2013, and evaluated its pre- and post-implementation effects using population-based surveys (Phase 1). The RE-AIM evaluation revealed a low degree of reaching residents and improved active guide knowledge, but unchanged physical activity levels. From 2015, we applied it to all districts, considering the Phase 1 results (Phase 2). We aimed to improve the degree of reach and focused on group exercise interventions intended to spread to residents. Elderly individuals who performed the group exercise showed improved physical fitness one year later and consistent physical activity and cognitive function. Then, the number of participants increased by 21% in a year. We extracted features of rules, roles, and tools as important aspects of smooth group activities, and created manuals. These findings are still utilized in Fujisawa city health promotion.Conclusion: This project involved RE-AIM evaluations and strategy improvement. Our findings were translated into the city's policy and scaled up. In Japan, in addition to increases in the practices, it is necessary to further disseminate and implement evaluation frameworks such as the RE-AIM model.

Physical activity, exercise, and health promotion for cancer survivors

OGUMA Yuko, SAITO Yoshinobu, TAJIMA Takayuki

Japanese Journal of Health Education and Promotion (JAPANESE SOCIETY OF HEALTH EDUCATION AND PROMOTION) 27 ( 1 ) 109 - 114 2019

ISSN 1340-2560

Introduction: Physical activity is known to reduce the risk of cancer morbidity and mortality, and to give the health benefits for cancer survivors. For example, after receiving cancer diagnosis, appropriate physical activity can improve prognosis afterwards. Evidence is available to show the risk of cancer-related mortality falls to 50% in the group that continues exercise after a cancer diagnosis. Previous interventional studies also show improvement in physical fitness, quality of life, mood, reduced anxiety and depression/fatigue, an effect on body image/body composition, and an improvement in biomarkers related to cancer risk and outcome.Current status of physical activities: Based on this evidence, the American Cancer Society/American College of Sports Medicine recommends that cancer survivors engage in 150 minutes per week of moderate-intensity aerobic physical activity (or 75 minutes/week of vigorous-intensity aerobic physical activity) and two strength training sessions per week, as well as decreased sedentary time. However, <30% of persons diagnosed with cancer are reported to meet the recommended levels. To maintain high physical activity in real life settings, a feasible strategy in society should be established.Toward Social Implementation: In the 2017 Clinical Practice Guidelines (Canada), evidence supports the promotion of exercise in a group or supervised settings. For sustainable engagement in physical activity, it is important to be able to exercise under guidance and to promote physical activities in daily life, depending on the situation.

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運動開始前の健康スクリーニング～誰が何をするのか～

小熊祐子

日本臨床運動療法学会誌 20 27 - 31 2019

健康長寿社会における身体活動と健康－「ふじさわプラス・テン」の取り組みを通して－

小熊祐子, 齋藤義信

予防医学 60 21 - 25 2019

脳心血管病予防に関する包括的リスク管理チャート2019年版について

小熊祐子, 井上茂, 永富良一

日内会誌 108 ( 5 ) 1024 - 1070 2019

Prevalence of Metabolic Syndrome and Lifestyle Characteristics by Business Type among Japanese Workers in Small- and Medium-sized Enterprises

Hozawa, H., Takeuchi, A. and Oguma, Y.

Keio J Med (Keio Journal of Medicine) 68 ( 3 ) 54 - 67 2018.12

Joint Work, ISSN 0022-9717

This cross-sectional study investigated the associations of business type with the prevalence of metabolic syndrome (MetS) and lifestyle characteristics among workers in small- and medium-sized enterprises. In total, data from 167,736 workers (114,746 men and 52,990 women) who participated in health checkups in 2013 were analyzed using multilevel logistic regression models. The odds ratios (ORs) of having MetS, defined based on the criteria of the joint interim statement, were significantly higher in employees of transportation businesses (reference OR =1) than in other business types among men (OR: 0.67-0.85) and similar result was observed among women (OR: 0.70-0.88). The prevalence of a smoking habit was significantly higher in transportation workers than in employees of other businesses for both men and women. Furthermore, male transportation workers were more likely to skip breakfast, engage in <1 h/day of walking, walk at a slower speed, and eat dinner just before going to bed. Female transportation workers were more likely to have gained 10 kg since the age of 20 years. In conclusion, the prevalence of MetS was higher in transportation workers than in workers from other businesses; the associated risk factors may also vary by sex. To effectively promote public health, the labor environment, such as the business type, should be considered.

Elevated creatine kinase and lactic acid dehydrogenase and decreased osteocalcin and uncarboxylated osteocalcin are associated with bone stress injuries in young female athletes

T Miyamoto, Y Oguma, Y Sato, T Kobayashi, E Ito, M Tani, K Miyamoto, ...

Scientific reports 8 (1), 18019 (Scientific Reports) 8 ( 1 ) 18019 - 18019 2018.12

Joint Work, ISSN 2045-2322

© 2018, The Author(s). Stress fractures are a limitation for athletes not only in sports performance but in activities of daily living. Thus, preventing them is crucial. In female athletes, a triad of symptoms including low energy availability, functional hypothalamic amenorrhea and osteoporosis are considered risk factors for stress injuries, but biomarkers predictive of these outcomes are not available. Here, we evaluated 56 female university athletes and found that 13 had a history of stress bone injuries. Logistic regression analysis demonstrated that dysmenorrhea including amenorrhea, but not reduced food intake or body weight loss, was significantly associated with stress injuries. When we subdivided subjects into stress fracture and non-fracture groups, we found that serum levels of creatine kinase (CK) and lactic acid dehydrogenase (LDH) were significantly higher in the fracture group, while osteocalcin and uncarboxylated osteocalcin (ucOC), which are bone forming parameters, significantly decreased. Low vitamin D levels are associated with stress fractures, but serum vitamin D levels were higher in fracture compared to non-fracture subjects. We followed up 32 subjects for

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Relationship of objectively measured physical activity and physical function of community-dwelling very old in Kawasaki, Japan: baseline assessment of Kawasaki well-being prospective cohort study

Oguma Yuko, Tajima Takayuki, Saito Yoshinobu, Fukui Shogo, Kibayashi Yayoi, Yoshida Natsuko, Ishida Hiroyuki, Hirata Takumi, Abe Yukiko, Arai Yasumichi

JOURNAL OF PHYSICAL ACTIVITY & HEALTH 15 ( 10 ) S34 - S34 2018.10

ISSN 1543-3080

Physical Activity Among Postoperative Esophageal Cancer Patients

Ichijo, Y., Takeda, Y., Oguma, Y., Kitagawa, Y., Takeuchi, H. and Doorenbos, A. Z.

Cancer Nurs (Cancer nursing) 42 ( 6 ) 501 - 508 2018.09

Joint Work, ISSN 0162-220X

BACKGROUND: Previous literature has reported that regular physical activity enhances health-related quality of life for cancer patients. However, there is a lack of studies that focus on physical activity among postoperative esophageal cancer patients. OBJECTIVE: The aims of this study were to (1) describe the prevalence of physical activity among postoperative esophageal cancer patients, (2) explore variables related to physical activity (demographics, nutrition, dysphagia, and health-related qualify of life), and (3) examine potential reasons for inactivity among participants who scored low using case studies. METHODS: In this cross-sectional design, physical activity was evaluated by the Japanese version of the International Physical Activity Questionnaire. Variables were analyzed using Spearman rank correlation coefficients, Mann-Whitney U tests, or Fisher exact tests. RESULTS: Fifty-eight patients participated in this study; 79% met the recommended physical activity guidelines. Present occupational status and past leisure-time physical activity behavior before the cancer diagnosis were related to current leisure-time physical activity and meeting the guidelines postoperatively. Participants who scored 0 (little or no activity) in the questionnaire also scored low in health-related quality of life. CONCLUSIONS: Participants performed especially well in physical activity related to leisure time and transportation. Positive reinforcement is needed for patients who perform adequate levels of physical activity, and reviewing the benefits of regular physical activity is encouraged for all. IMPLICATIONS FOR PRACTICE: Occupational status and past leisure-time physical activity before diagnosis can be indicators for promoting physical activity among postoperative esophageal cancer patients. Inactive participants should be supported to promote both physical activity and health-related qualify of life.

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高齢者地域コミュニティのグループ運動継続に関わる特徴

柴, 知里, 齋藤, 義信, 今村, 晴彦, 田中, あゆみ, 土村, 里佳 and 小熊, 祐子

日本健康教育学会誌 (日本健康教育学会) 26 ( 2 ) 144 - 154 2018.05

Joint Work, ISSN 1340-2560

目的:高齢者地域コミュニティのグループ運動継続に関わる特徴を把握する。事業/活動内容:対象は藤沢市で実施中の身体活動促進のための地域介入研究に参加し、6ヵ月間グループ運動を継続している8グループ(120名)である。研究参加時、6ヵ月後時点で質問紙調査、体力測定、認知機能評価を行った。運動プログラムやモニタリングツールを提供し、定期的なフォローアップや交流会、グループワークを行った。事業/活動評価:(1)リーダーの特徴と協力者の有無および協力の主体性で8グループを4群に分類し、質問紙による身体活動量、精神的健康、地域とのつながり、個人要因を比較した。(2)グループ向け質問紙、交流会、グループワークの質的情報から、グループの特徴を比較した。結果を統合してコミュニティづくりに重要なルール(自生した規則や制度)、ロール(自発的な役割)、ツール(道具や資源)の観点からグループの特徴を把握した。活動基盤となるルールは、全グループ共通のル

Maintenance Of Physical Activity Level And Dissemination Of "Plus Ten" Message In Community-based Group Exercise

Saito Yoshinobu, Oguma Yuko, Tajima Takayuki, Tanaka Ayumi, Kibayashi Yayoi, Shiba Chisato, Miyachi Motohiko, Takebayashi Toru

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE 50 ( 5 ) 62 - 63 2018.05

Joint Work, ISSN 0195-9131

地域在住高齢者における個人レベルのソーシャル・キャピタルと身体活動との関連　横断研究

齋藤, 義信, 小熊, 祐子, 田島, 敬之, 加藤, 梨里, 木林, 弥生, 宮地, 元彦 and 武林, 亨

体力科学 ((一社)日本体力医学会) 67 ( 2 ) 177 - 185 2018.04

Joint Work, ISSN 0039-906X

「健康と生活に関するアンケート」に回答した高齢者534名(男性260名、女性274名、68〜78歳)を対象とした。男女の比較で有意差を認めた人口統計学的属性・社会経済的属性は、居住形態(女性の独居割合が高い)、BMI(男性が高い)、身体活動の制限(女性の医師または足腰の痛みによる制限がある割合が高い)、教育歴(男性の大学卒以上の割合が高い)、収入がある仕事(男性の仕事をもつ割合が高い)であった。ソーシャル・キャピタル(SC)では地域の人とのかかわりと他世代との交流において有意な男女差(女性のSCが高い)を認めた。SCが低いと想定される回答を基準とした解析で、男性では、地域の支え合い:支え合うと思う、地域の人とのかかわり:立ち話をする人がいる、相談しあえる人がいる、他世代との交流:まあまあある、とてもあるにおいて有意な正の関連を認めた。トレンド検定では、有意な量反応関係を認めた。女性では、地域の人とのかかわり:相談しあえる人がいる、地域組織活動へ

Awareness of physical activity promotion, physical activity, and sedentary behavior in elderly Japanese

Tajima, Takayuki, Saito, Yoshinobu, Kato, Riri, Kibayashi, Yayoi, Miyachi, Motohiko, Lee, I-Min and Oguma, Yuko

The Journal of Physical Fitness and Sports Medicine (一般社団法人日本体力医学会) 7 ( 2 ) 113 - 119 2018.03

Joint Work, ISSN 2186-8131

本研究の目的は、日本人高齢者を対象に「アクティガイド」や「プラス・テン」などの身体活動プロモーションの認知と身体活動時間、座位行動時間の関連について検討することである。我々は2013年より神奈川県藤沢市において身体活動促進のためのコミュニティワイドキャンペーンを実施している。この取り組みの成果評価及び2015年度以降に行う全市的な介入の事前評価の位置づけで、2015年6月に20歳以上の藤沢市民3,000名を無作為抽出して質問紙調査を実施した。本研究ではその質問紙調査を用い、65歳以上の高齢者874名を対象者とした。このうち550名から返答があり、データに欠損のない373名を解析に用いた。48%(179/373名)が「アクティブガイド」や「プラス・テン」などの身体活動プロモーションを認知していた。身体活動時間(運動を行っている時間と歩行またはそれと同等以上の強度の生活活動を行っている時間の総和)の中央値は100分/日、座位行動時間の中央値は300分/日であった。身体活動プロモーションの認知と身体活動時間には有意な関連はみられなかったが(Odds Ratio(OR) for≧100minutes/day)=1.02,95% Confidence Interval(CI)=0.65-1.62)、座位行動時間との間には有意な関連性がみられた(OR for<300minutes/day)=1.60,95%CI=1.01-2.53)。高齢者において、強度を問わず日に40分以上の身体活動をすすめるアクティブガイドや、皆に今より10分多く体を動かすことをすすめるプラス・テンというメッセージの認知をすることは、高齢者において座位行動を減少させる可能性が示唆された。(著者抄録)

Association of high individual-level of social capital with increased physical activity among community-dwelling elderly men and women: A cross-sectional study

Y Saito, Y Oguma, T Tajima, R Kato, Y Kibayashi, M Miyachi, ...

Japanese Journal of Physical Fitness and Sports Medicine 67 (2), 177-185 (Japanese Journal of Physical Fitness and Sports Medicine) 67 ( 2 ) 177 - 185 2018

Research paper (scientific journal), Joint Work, ISSN 0039906X

We aimed to evaluate the associations of individual-level social capital (SC) and physical activity (PA) among Japanese elderly men and women. Individuals aged 65 or above were selected via population-based random sampling of 3000 adults, aged 20 years or above and living in Fujisawa city, who were asked to complete self-administered questionnaires. The sample consisted of 260 men [median (25-75% tile) age 73 (68-78) yrs] and 274 women [73 (68-78) yrs]. The daily duration of PA, SC [e.g., norms of reciprocity (mutual support in the community), social networks (relationship with community people, exchange with other generations), social participation (participation in community organization activities)], socio-economic status [educational attainment, work with income, perceived household economic status], and demographic characteristics [sex, age, living arrangements, BMI, physical limitations] were assessed. Multivariate logistic regression analyses were used to calculate odds ratios (OR) for associations of SC with PA, stratified by sex. High level of mutual support in the community, relationship with community people, and exchange with other generations were associated with longe

Effects of replacing sedentary behavior with different intensities of physical activity on physical function among community-dwelling elderly: A cross-sectional study

T Tajima, Y Saito, Y Kibayashi, Y Oguma

JOURNAL OF PHYSICAL ACTIVITY & HEALTH 15 (10), S233-S234 (International Society of Physical Activity and Health) 15 ( 10 ) S233 - S234 2018

Joint Work, ISSN 1543-3080

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