Papers - Arita, Makoto
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n-3 fatty acids effectively improve the reference memory-related learning ability associated with increased brain docosahexaenoic acid-derived docosanoids in aged rats.
*Hashimoto M, Katakura M, Tanabe Y, Al Mamun A, Inoue T, Hossain S, Arita M, Shido O.
Biochim Biophys Acta 1851 203 - 209 2015
Research paper (scientific journal), Joint Work, Accepted
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Combination therapy of 15-epi-lipoxin A4 with antibiotics protects mice from Escherichia coli-induced sepsis.
Ueda T, *Fukunaga K, Seki H, Miyata J, Arita M, Miyasho T, Obata T, Asano K, Betsuyaku T, Takeda J.
Crit Care Med 42 e288 - 295 2014
Research paper (scientific journal), Joint Work, Accepted
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The arachidonic acid metabolome as conserved regulator of cholesterol metabolism.
Demetz E, Schroll A, Auer K, Heim C, Patsch JR, Eller P, Theurl M, Lener D, Stanzl U, Seifert M, Haschka D, Asshoff M, Dichtl S, Nairz M, Huber E, Stadlinger M, Li X, Pallweber P, Scharnagl H, Stojakovic T, Marz W, Kleber ME, Garlaschelli K, Uboldi P, Catapano AL, Stellaard F, Rudling M, Kuba K, Imai Y, Arita M, Pramstaller PP, Tietge UJF, Trauner M, Norata GD, Claudel T, Hicks AA, Weiss G, *Tancevski I.
Cell Metab 20 787 - 798 2014
Research paper (scientific journal), Joint Work, Accepted
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Immunomodulation with eicosapentaenoic acid supports the treatment of autoimmune small-vessel vasculitis.
*Hirahashi J, Kawahata K, Arita M, Iwamoto R, Hishikawa K, Honda M, Hamasaki Y, Tanaka M, Okubo K, Kurosawa M, Takase O, Nakakuki M, Saiga K, Suzuki K, Kawachi S, Tojo A, Seki G, Marumo T, Hayashi M, Fujita T.
Sci Rep 4 6406 2014
Research paper (scientific journal), Joint Work, Accepted
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A design strategy for small molecule-based targeted MRI contrast agents: their application for detection of atherosclerotic plaques.
Iwaki S, Hokamura K, Ogawa M, Takehara Y, Muramatsu Y, Yamane T, Hirabayashi K, Morimoto Y, Hagisawa K, Nakahara K, Mineno T, Terai T, Komatsu T, Ueno T, Tamura K, Adachi Y, Hirata Y, Arita M, Arai H, Umemura K, Nagano T, *Hanaoka K.
Org Biomol Chem 12 8611 - 8618 2014
Research paper (scientific journal), Joint Work, Accepted
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18-HEPE, an n-3 fatty acid metabolite released by macrophages, prevents pressure overload-induced maladaptive cardiac remodeling.
Endo J, Sano M, Isobe Y, Fukuda K, Kang JX, Arai H, *Arita M.
J Exp Med 211 1673 - 1687 2014
Research paper (scientific journal), Joint Work, Accepted
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Identification of 14,20-dihydroxy-docosahexaenoic acid as a novel anti-inflammatory metabolite.
Yokokura Y, Isobe Y, Matsueda S, Iwamoto R, Goto T, Yoshioka T, Urabe D, Inoue M, Arai H, *Arita M.
J Biochem 156 315 - 321 2014
Research paper (scientific journal), Joint Work, Accepted
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Eosinophils control the resolution of inflammation and draining lymph node hypertrophy through the proresolving mediators and CXCL13 pathway in mice.
Tani Y, Isobe Y, Imoto Y, Segi-Nishida E, Sugimoto Y, Arai H, *Arita M.
FASEB J 28 4036 - 4043 2014
Research paper (scientific journal), Joint Work, Accepted
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Rapidly rendering cells phagocytic through a cell-surface display technique and concurrent Rac activation.
Onuma H, *Komatsu T, Arita M, Hanaoka K, Ueno T, Terai T, Nagano T, *Inoue T.
Sci Signal 7 rs4 2014
Research paper (scientific journal), Joint Work, Accepted
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Regulation of intestinal IgA responses by dietary palmitic acid and its metabolism.
*Kunisawa J, Hashimoto E, Inoue A, Nagasawa R, Suzuki Y, Ishikawa I, Shikata S, Arita M, Aoki J, Kiyono H.
J Immunol 193 1666 - 1671 2014
Research paper (scientific journal), Joint Work, Accepted
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Eicosapentaenoic acid is converted via omega-3 epoxygenation to anti-inflammatory metabolite 12-hydroxy-17,18-epoxyeicosatetraenoic acid.
Kubota T, *Arita M, Isobe Y, Iwamoto R, Goto T, Yoshioka T, Urabe D, Inoue M, Arai H.
FASEB J 28 586 - 593 2014
Research paper (scientific journal), Joint Work, Accepted
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Basophils regulate the recruitment of eosinophils in a murine model of irritant contact dermatitis.
Nakashima C, *Otsuka A, Kitoh A, Honda T, Egawa G, Nakajima S, Nakamizo S, Arita M, Kubo M, Miyachi Y, *Kabashima K.
J Allergy Clin Immunol 134 100 - 107 2014
Research paper (scientific journal), Joint Work, Accepted
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Matrix metalloproteinase (MMP)-9 in cancer-associated fibroblasts (CAFs) is suppressed by omega-3 polyusaturated fatty acids in vitro and in vivo.
Taguchi A, *Kawana K, Tomio K, Yamashita A, Isobe Y, Nagasaka K, Koga K, Inoue T, Nishida H, kojima S, Adachi K, Matsumoto Y, Arimoto T, Wada-Hiraike O, Oda K, kang JX, Arai H, *Arita M, Osuga Y, Fujii T.
PLoS One 27 e89605 2014
Research paper (scientific journal), Joint Work, Accepted
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Omega-3 fatty acids protect renal functions by increasing docosahexaenoic acid-derived metabolite levels in SHR.Cg-Leprcp/NDmcr rats, a metabolic syndrome model.
Katakura M, *Hashimoto M, Inoue T, Al Mamun A, Tanabe Y, Iwamoto R, Arita M, Tsuchikura S, Shido O.
Molecules 19 3247 - 3263 2014
Research paper (scientific journal), Joint Work, Accepted
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Effects of long-term oral administration of arachidonic acid and docosahexaenoic acid on the immune functions of young rats.
Juman S, *Hashimoto M, Katakura M, Inoue T, Tanabe Y, Arita M, Miki T, Shido O.
Nutrients 5 1949 - 1961 2013
Research paper (scientific journal), Joint Work, Accepted
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Increased tissue level of omega-3 polyunsaturated fatty acids prevents pathological preterm birth.
Yamashita A, *Kawana K, Tomio K, Taguchi A, Isobe Y, Iwamoto R, Masuda K, Furuya H, Nagamatsu T, Nagasaka K, Oda K, Wada-Hiraike O, Yamashita T, Taketani Y, Kang JX, Arai H, *Arita M, Kozuma S, Fujii T.
Sci Rep 3 3113 2013
Research paper (scientific journal), Joint Work, Accepted
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Omega-3 polyunsaturated fatty acids suppress the cystic lesion formation of peritoneal endometriosis in transgenic mouse models.
Tomio K, *Kawana K, Taguchi A, Isobe Y, Iwamoto R, Yamashita A, Kojima S, Mori M, Nagamatsu T, Arimoto T, Oda K, Osuga Y, Taketani Y, Kang JX, Arai H, *Arita M, Kozuma S, Fujii T.
PLoS One 8 e73085 2013
Research paper (scientific journal), Joint Work, Accepted
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Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition.
Kishino S, Takeuchi M, Park S, Hirata A, Kitamura N, Kunisawa J, Kiyono H, Iwamoto R, Isobe Y, Arita M, Arai H, Ueda K, Shima J, Takahashi S, Yokozeki K, Shimizu S, *Ogawa J.
Proc Natl Acad Sci USA 110 17808 - 17813 2013
Research paper (scientific journal), Joint Work, Accepted
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The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza.
Morita M, Kuba K, Ichikawa A, Nakayama M, Katahira J, Iwamoto R, Watanabe T, Sakabe S, Daidoji T, Nakamura S, Kadowaki A, Ohto T, Nakanishi H, Taguchi R, Nakaya T, Murakami M, Yoneda Y, Arai H, Kawaoka Y, Penninger JM, Arita M, *Imai Y.
Cell 153 112 - 125 2013
Research paper (scientific journal), Joint Work, Accepted
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Dysregulated synthesis of protectin D1 in eosinophils from patients with severe asthma.
Miyata J, Fukunaga K, Iwamoto R, Isobe Y, Niimi K, Takamiya R, Takihara T, Tomomatsu K, Suzuki Y, Oguma T, Sayama K, Arai H, Betsuyaku T, Arita M, *Asano K.
J Allergy Clin Immunol 131 353 - 360 2013
Research paper (scientific journal), Joint Work, Accepted