Papers - Arita, Makoto

Gut microbiota-derived lipid metabolites facilitate regulatory T cell differentiation.

Shiratori H, Oguchi H, Isobe Y, Han KH, Sen A, Yakebe K, Takahashi D, Fukushima M, *Arita M, *Hase K

Scientific Reports 13   8903 2023.06

Research paper (scientific journal), Joint Work, Corresponding author, Accepted

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Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction-associated fatty liver disease.

*Lopez-Vicario C, Sebastian D, Casulleras M, Duran-Guell M, Flores-Costa R, Aguilar F, Lozano JJ, Zhang IW, Titos E, Kang JX, Zorzano A, Arita M, *Claria J.

Hepatology 77   1303 - 1318 2023.04

Research paper (scientific journal), Joint Work, Accepted

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Enzymatically-epoxidized docosahexaenoic acid, 19,20-EpDPE, suppresses hepatic crown-like structure formation and nonalcoholic steatohepatitis fibrosis through GPR120.

Aoki H, Isobe Y, Yoshida M, Kang JX, Maekawa M, *Arita M.

Biochim Biophys Acta Mol Cell Biol Lipids 1868 ( 3 ) 159275 2023.03

Research paper (scientific journal), Joint Work, Last author, Corresponding author, Accepted

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Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via regulation of pyruvate dehydrogenase (PDH) phosphorylation.

Ikizawa T, Ikeda K, Arita M, Kitajima S, Soga T, *Ichijo H, *Naguro I.

Journal of Biological Chemistry 299 ( 2 ) 102837 2023.02

Research paper (scientific journal), Joint Work, Accepted

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Dysregulated ceramide metabolism in mouse progressive dermatitis resulting from constitutive activation of Jak1

Iino Y, Naganuma T, *Arita M.

Journal of Lipid Research 64   100329 2023.02

Research paper (scientific journal), Joint Work, Last author, Corresponding author, Accepted

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Computational mass spectrometry accelerates C=C position-resolved untargeted lipidomics using oxygen attachment dissociation

Uchino H, *Tsugawa H, Takahashi H, *Arita M.

Communications Chemistry 5   162 2022.12

Joint Work, Last author, Corresponding author, Accepted

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Sterol O-acyltransferase inhibition ameliorates high-fat diet-induced renal fibrosis and tertiary lymphoid tissue maturation after ischemic reperfusion injury.

Ariyasu Y, Sato Y, Isobe Y, Taniguchi K, *Yanagita M, *Arita M.

Int J Mol Sci  23 ( 24 ) 15465 2022.12

Research paper (scientific journal), Joint Work, Last author, Corresponding author, Accepted

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Genetic deletion of Cyp4f18 disrupts the omega-3 epoxidation pathway and results in psoriasis-like dermatitis.

Yoshida M, Ishihara T, Isobe Y, *Arita M.

FASEB Journal 36 ( 12 ) e22648 2022.11

Research paper (scientific journal), Joint Work, Last author, Corresponding author, Accepted

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Comprehensive analysis of 10-hydroxy-cis-12-octadecenoic acid (HYA) and related fatty acid metabolites produced by gut microbiota using LC-MS/MS-based lipidomics.

*Tsuji K, Shimada W, Kishino S, Ogawa J, Arita M.

Medical Mass Spectrometry 6 ( 2 ) 112 - 125 2022.11

Research paper (scientific journal), Joint Work, Last author, Accepted

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Pleiotropic roles of cholesteryl sulfate during Entamoeba encystation; involvement in cell rounding and development of membrane impermeability.

*Mi-ichi F, Tsugawa H, Arita M, Yoshida H.

mSphere  7   e0029922 2022.08

Research paper (scientific journal), Joint Work, Accepted

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Introducing the lipidomics minimal reporting checklist.

McDonald JG, Ejsing CS, Kopczynski D, Holcapek M, Aoki J, Arita M, Arita M, Baker ES, Bertrand-Michel J, Bowden JA, Brugger B, Ellis SR, Fedorova M, Griffiths WJ, Han X, Hartler J, Hoffmann N, Koelmel JP, Kofeler HC, Mitchell TW, O’Donnell VB, Saigusa D, Schwudke D, Shevchenko A, Ulmer CZ, Wenk MR, Witting M, Wolrab D, Xia Y, *Ahrends R, *Liebisch G, *Ekroos K.

Nature Metabolism 4   1086 - 1088 2022.08

Research paper (scientific journal), Joint Work, Accepted

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Microbiota-independent spontaneous dermatitis associated with increased sebaceous lipid production in Tmem79-deficient mice.

Morimoto K, Fukuda K, Ito Y, Tahara U, Sasaki T, Shiohama A, Kawasaki H, Kawakami E, Naganuma T, Arita M, Sasaki H, Koseki H, Matsui T, *Amagai M.

J Invest Dermatol  142 ( 11 ) 2864 - 2872 2022.06

Research paper (scientific journal), Joint Work, Accepted

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Lipidomic analysis revealed n-3 polyunsaturated fatty acids suppressed choroidal thinning and myopia progression in mice.

Mori K, Kuroha S, Hou J, Jeong H, Ogawa M, Ikeda S, Kang JX, Negishi K, Torii H, *Arita M, *Kurihara T, Tsubota K.

FASEB Journal 36   e22312 2022.06

Research paper (scientific journal), Joint Work, Corresponding author, Accepted

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Group IIA secreted phospholipase A2 controls skin carcinogenesis and psoriasis by shaping the gut microbiota.

Miki Y, Taketomi Y, Kidoguchi Y, Yamamoto K, Muramatsu K, Nishito Y, Park J, Hosomi K, Mizuguchi K, Kunisawa J, Soga T, Boilard E, Gowda SG, Ikeda K, Arita M, *Murakami M.

JCI Insight 7   e152611 2022.01

Research paper (scientific journal), Joint Work, Accepted

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The interaction of secreted phospholipase A2-IIA with the microbiota alters its lipidome and promotes inflammation.

Dore E, Joly-Beauparlant C, Morozumi S, Mathieu A, Levesque T, Allaeys I, Duchez A, Cloutier N, Leclercq M, Bodein A, Payre C, Martin C, Petit-Paitel A, Gelb M, Rangachari M, Murakami M, Davidovic L, Flamand N, Arita M, Lambeau G, Droit A, *Boilard E.

JCI Insight 7   e152638 2022.01

Research paper (scientific journal), Joint Work, Accepted

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Intestinal microbiome-dependent w3 lipid metabolite aKetoA prevents inflammatory diseases in mice and cynomolgus macaques.

Nagatake T, Kishino S, Urano E, Murakami H, Kitamura N, Konishi K, Ohno H, Tiwari P, Morimoto S, Node E, Adachi J, Abe Y, Isoyama J, Sawane K, Honda T, Inoue A, Uwamizu A, Matsuzaka T, Miyamoto Y, Hirata S, Saika A, Shibata Y, Hosomi K, Matsunaga A, Shimano H, Arita M, Aoki J, Oka M, Matsutani A, Tomonaga T, Kabashima K, Miyachi M, Yasutomi Y, Ogawa J, *Kunisawa J.

Mucosal Immunology 15   289 - 300 2022.01

Research paper (scientific journal), Joint Work, Accepted

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Oxidized phospholipids and neutrophil elastase coordinately play critical roles in NET formation.

Tokuhiro T, Ishizawa A, Sato H, Takita S, Yoshikawa A, Anzai R, Sato S, Aoyagi R, Arita M, Aratani Y, Shimizu S, Tanaka M, *Yotsumoto S.

Frontiers in Cell and Developmental Biology 9   718586 2021.09

Research paper (scientific journal), Joint Work, Accepted

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Comparative analysis of single-molecule dynamics of TRPV1 and TRPV4 channels in living cells

Kuwashima Y, *Yanagawa M, Abe M, Hiroshima M, Ueda M, Arita M, *Sako Y

Int J Mol Biol  22   8473 2021.08

Research paper (scientific journal), Joint Work, Accepted

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Long-chain saturated fatty acids in breast milk are associated with the pathogenesis of atopic dermatitis via induction of inflammatory ILC3s.

Kong WS, Tsuyama N, Inoue H, Guo Y, Mokuda S, Nobukiyo A, Nakatani N, Yamaide F, Nakano T, Kohno Y, Ikeda K, Nakanishi Y, Ohno H, Arita M, Shimojo N, *Kanno M.

Scientific Reports 11 ( 1 ) 13109 2021.06

Research paper (scientific journal), Accepted

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GPR120 signaling controls amyloid-β degrading activity of matrix metalloproteinases.

Kikuchi K, Tatebe T, Sudo Y, Yokoyama M, Kidana K, Chiu Y, Takatori S, Arita M, Hori Y, *Tomita T

Journal of Neuroscience 41 ( 28 ) 6173 - 6185 2021.06

Research paper (scientific journal), Joint Work, Accepted

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