Papers - Arita, Makoto

Formation of giant ER sheets by pentadecanoic acid causes lipotoxicity in fission yeast.

Hoshikawa Y, Shirota N, Tsugawa H, Kimura S, Matsuyama A, Yashiroda Y, Arita M, Fenical W, Yoshida M, *Nishimura S.

Proc Natl Acad Sci USA 122 ( 22 ) e2422126122 2025.05

Research paper (scientific journal), Joint Work, Accepted

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Technical recommendations for analyzing oxylipins by liquid chromatography-mass spectrometry.

*Schebb NH, Kampschulte N, Hagn G, Plitzko K, Meckelmann SW, Ghosh S, Joshi R, Kuligowski J, Vuckovic D, Botana MT, Sánchez-Illana Á, Zandkarimi F, Das A, Yang J, Schmidt L, Checa A, Roche HM, Armando AM, Edin ML, Lih FB, Aristizabal-Henao JJ, Miyamoto S, Giuffrida F, Moussaieff A, Domingues R, Rothe M, Hinz C, Das US, Rund KM, Taha AY, Hofstetter RK, Werner M, Werz O, Kahnt AS, Bertrand-Michel J, Le Faouder P, Gurke R, Thomas D, Torta F, Milic I, Dias IHK, Spickett CM, Biagini D, Lomonaco T, Idborg H, Liu JY, Fedorova M, Ford DA, Barden A, Mori TA, Kennedy PD, Maxey K, Ivanisevic J, Gallart-Ayala H, Gladine C, Wenk M, Galano JM, Durand T, Stark KD, Barbas C, Garscha U, Gelhaus SL, Ceglarek U, Flamand N, Griffin JL, Ahrends R, Arita M, Zeldin DC, Schopfer FJ, Quehenberger O, Julian R, Nicolaou A, Blair IA, Murphy MP, Hammock BD, Freeman B, Liebisch G, Serhan CN, Köfeler HC, Jakobsson PJ, Steinhilber D, Gelb MH, Holčapek M, Andrew R, Giera M, FitzGerald GA, Murphy RC, Newman JW, Dennis EA, Ekroos K, Milne GL, Gijón MA, Vesper HW, Wheelock CE, O'Donnell VB.

Science Signaling 18 ( 887 ) eadw1245 2025.05

Research paper (scientific journal), Joint Work, Accepted

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Porphyran from discolored nori prevents metabolic syndrome through microbiota-bile acid-ceramide pathway.

Yokoyama Y, Takashima Y, Morel JD, Taworntawat T, Kitamura N, Nagano U, Tanigaki T, Nakamura A, Miyazaki T, Taoka H, Mottis A, Perino A, Shinjo A, Suzuki N, Takekawa S, Fukuda S, Honda A, Ishihara K, Arita M, Tsubota K, Auwerx J, *Watanabe M.

iScience  28 ( 6 ) 112603 2025.05

Research paper (scientific journal), Joint Work, Accepted

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Transcriptomic and lipidomic analysis of aging-associated inflammatory signature in mouse liver.

*Ishihara T, Tsugawa H, Iwanami S, Chang JC, Minoda A, *Arita M.

Inflammation and Regeneration 45 ( 1 ) 13 2025.05

Research paper (scientific journal), Joint Work, Last author, Corresponding author, Accepted

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Eosinophils and pleural macrophages counterregulate IL-33-elicited airway inflammation via the 12/15-lipoxygenase pathway.

Ito E, Hayashizaki R, Hosaka T, Yamane T, Miyata J, *Isobe Y, *Arita M.

Frontiers in Immunology 16   1565670 2025.04

Research paper (scientific journal), Joint Work, Last author, Corresponding author, Accepted

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Data-independent acquisition coupled with electron-activated dissociation for in-depth structure elucidation of the fatty acid ester of hydroxy fatty acids.

Kurizaki Y, Matsuzawa Y, Takahashi M, Takeda H, Hasegawa M, Arita M, Miyamoto J, *Tsugawa H.

Analytical Chemistry 97 ( 14 ) 7861 - 7868 2025.04

Research paper (scientific journal), Joint Work, Accepted

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Celecoxib prevents malignant progression of smoking-induced lung tumors via suppression of the COX-2/PGE2 signaling pathway in mice.

Sakurai K, *Chubachi S, *Miyata J, Hamamoto J, Naganuma T, Shimada T, Otake S, Nakayama S, Irie H, Tsutsumi A, Kameyama N, Hegab AE, Shimoda M, Terai H, Yasuda H, Kanai Y, Arita M, Fukunaga K.

Front Immunol  16   1557790 2025.03

Research paper (scientific journal), Joint Work, Accepted

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12/15-lipoxygenase-derived electrophilic lipid modifications in phagocytic macrophages.

Deng K, *Isobe Y, Tsumagari K, Kato T, Arai H, Imami K, *Arita M.

ACS Chem. Biol. 20 ( 2 ) 357 - 368 2025.02

Research paper (scientific journal), Joint Work, Last author, Corresponding author, Accepted

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Characterization of UGT8 as a monogalactosyl diacylglycerol synthase in mammals.

Ohba Y, Motohashi M, *Arita M.

J. Biochem. 177 ( 2 ) 141 - 152 2025.02

Research paper (scientific journal), Joint Work, Last author, Corresponding author, Accepted

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IL-5-producing group 2 innate lymphoid cells promote T cell-independent IgA production in cooperation with eosinophils.

*Yanagibashi T, Ikutani M, Nagai T, Arita M, Watanabe Y, Nagai Y, *Takatsu K.

Int. Immunol. in press 2024.12

Research paper (scientific journal), Joint Work, Accepted

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MS-DIAL 5 multimodal mass spectrometry data mining unveils lipidome complexities.

Takeda H, Matsuzawa Y, Takeuchi M, Takahashi M, Nizhida K, *Harayama T, Todoroki Y, Shimizu K, Sakamoto N, Oka T, Maekawa M, Chung MH, Kurizaki Y, Kiuchi S, Kvasnička A, Takeda U, Uchino H, Hasegawa M, Miyamoto J, Tanabe K, Takeda S, Mori T, Tanaka T, Yoshino T, Saito K, Okamoto M, Takahashi H, *Arita M, *Tsugawa H.

Nature Communications 15   9903 2024.11

Research paper (scientific journal), Joint Work, Corresponding author, Accepted

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MS2Lipid: A lipid subclass prediction program using machine learning and curated tandem mass spectral data.

Sakamoto N, Oka T, Matsuzawa Y, Nishida K, Jayaprakash J, Hori A, *Arita M, *Tsugawa H.

Metabolites 14   602 2024.11

Research paper (scientific journal), Corresponding author, Accepted

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Inflammatory profile of eosinophils in asthma-COPD overlap and eosinophilic COPD: A multi-omics study.

Sunata K, *Miyata J, Kawashima Y, Konno R, Ishikawa M, Hasegawa Y, Onozato R, Otsu Y, Matsuyama E, Sasaki H, Okuzumi S, Mochimaru T, Masaki K, Kabata H, Chubachi S, Arita M, Fukunaga K.

Frontiers in Immunology 15   1445769 2024.10

Research paper (scientific journal), Accepted

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Concordant inter-laboratory derived concentrations of ceramides in human plasma reference.

Torta F, Hoffmann N, Burla B, Alecu I, Arita M, Bamba T, Bennett SAL, Bertrand-Michel J, Brugger B, Cala MP, Camacho-Munoz D, Checa A, Chen M, Chocholouskova M, Cinel M, Chu-Van E, Colsch B, Coman C, Connell L, Sousa BD, Dickens AM, Fedorova M, Eriksson FF, Gallart-Ayala H, Ghorasaini M, Giera M, Guan XL, Haid M, Hankmeier T, Harms A, Horing M, Holcapek M, Hornemann T, Hu C, Hulsmeier A, Huynh K, Jones CM, Ivanisevic J, Izumi Y, Kofeler HC, Lam SM, Lange M, Lee JC, Liebisch G, Lippa K, Lopez-Clavijo AF, Manzi M, Martinefski MR, Math RGH, Mayor S, Meikle PJ, Monge ME, Moon MH, Muralidharan S, Nicolaou A, Nguyen-Tran T, O’Donnell VB, Oresic M, Ramanathan A, Riols F, Saigusa D, Schock TB, Schwartz-Zimmermann H, Shui G, Singh M, Takahashi M, Thorsteinsdottir M, Tomiyasu N, Tournadre A, Tsugawa H, Tyrrell V, van der Gugten G, Wakelam MO, Wheelock CE, Wolrab D, Xu G, Xu T, Boeden JA, *Ekroos K, *Ahrends R, *Wenk MR.

Nature Communications 15 ( 1 ) 8562 2024.10

Research paper (scientific journal), Joint Work, Accepted

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Commensal consortia decolonize Enterobacteriaceae via ecological control.

Furuichi M, Kawaguchi T, Pust M, Yasuma-Mitobe K, Plichta DR, Hasegawa N, Ohya T, Bhattarai S, Sasajima S, Aoto Y, Tuganbeav T, Yaginuma M, Ueda M, Okahashi N, Amafuji K, Kiridooshi Y, Sugita K, Strazer M, Avila-Pacheco J, Pierce K, Clish CB, Skelly AN, Hattori M, Nakamoto N, Caballero S, Norman JM, Olle B, Tanoue T, Suda W, Arita M, Bucci V, Atarashi K, *Xavier RJ, *Honda K.

Nature 633 ( 8031 ) 878 - 886 2024.09

Research paper (scientific journal), Joint Work, Accepted

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Group X Phospholipase A2 Links Colonic Lipid Homeostasis to Systemic Metabolism via Host-Microbiota Interaction.

Sato H, Taketomi Y, Murase R, Park J, Hosomi K, Mizuguchi K, Arita M, Kunisawa J, *Murakami M.

Cell Reports 43 ( 10 ) 114752 2024.09

Research paper (scientific journal), Joint Work, Accepted

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MAFB in macrophages regulates prostaglandin E2-mediated lipid mediator class switch through ALOX15 in ischemic acute kidney injury.

Kanai M, Nishino T, Daassi D, Kimura A, Liao C, Shahri ZJ, Wakimoto A, Gogoleva N, Usui T, Morito N, Arita M, *Takahashi S, *Hamada M.

Journal of Immunology 213 ( 8 ) 1212 - 1224 2024.09

Research paper (scientific journal), Joint Work, Accepted

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Spatiotemporally distinct roles of cyclooxygenase-1 and cyclooxygenase-2 at fetomaternal interface in mice.

Aikawa S, Matsuo M, Akeda S, Sugimoto Y, Arita M, Isobe Y, Sugiura Y, Taira S, Maeda R, Shimizu-Hirota R, Takeda N, Hiratsuka D, He X, Ishizawa C, Iida R, Fukui Y, Hiraoka T, Harada M, Wada-Hiraike O, Osuga Y, *Hirota Y.

JCI Insight  9 ( 19 ) e181865 2024.08

Joint Work, Accepted

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Characterization of Entamoeba fatty acid elongases: validation as targets and provision of promising leads for new drugs against amebiasis.

*Mi-ichi F, Tsugawa H, Vo TK, Kurizaki Y, Yoshida H, Arita M.

PLoS Pathogens  20 ( 8 ) e1012435 2024.08

Research paper (scientific journal), Joint Work, Last author, Accepted

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Multi-omics analysis identified IL-4-induced IL1RL1high eosinophils characterized by prominent cysteinyl leukotriene metabolism.

Sunata K, *Miyata J, Kawashima Y, Konno R, Ishikawa M, Hasegawa Y, Onozato R, Otsu Y, Matsuyama E, Sasaki H, Okuzumi S, Mochimaru T, Masaki K, Kabata H, Kawana A, Arita M, Fukunaga K.

Journal of Allergy and Clinical Immunology  154 ( 5 ) 1277 - 1288 2024.07

Research paper (scientific journal), Accepted

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