Details of a Researcher - Torii, Hidemasa

Papers - Torii, Hidemasa

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HIF inhibitor topotecan suppresses light-induced retinal degeneration in mice

Y Miwa, M Miyauchi, Y Katada, X Jiang, K Mori, H Torii, K Tsubota, ...

Investigative Ophthalmology & Visual Science 57 (12), 2736-2736 57 ( 12 ) 2016.09

Lead author, Last author, Corresponding author, ISSN 0146-0404

Comparison of the accuracy of intraocular lens power calculations for cataract surgery in eyes after phototherapeutic keratectomy

Yaguchi Yukari, Negishi Kazuno, Saiki Megumi, Torii Hidemasa, Tsubota Kazuo

Japanese Journal of Ophthalmology (Japanese Journal of Ophthalmology) 60 ( 5 ) 1 - 8 2016.06

ISSN 0021-5155

Purpose: To compare the accuracy of several methods of intraocular lens (IOL) power calculations used for cataract surgery in eyes treated with phototherapeutic keratectomy (PTK) that results in changes in the anterior corneal surface and axial length; these results make power calculations less predictable. Methods: We evaluated the medical records of 23 eyes of 13 patients (mean age, 68.8 years; range 62–80 years) who underwent cataract surgery after PTK at Keio University Hospital, Tokyo, Japan. The prediction error, defined as the difference between the estimated postoperative spherical equivalent and the postoperative manifest refraction at the spectacle plane, was calculated using five formulas: SRK/T, Haigis-L, Shammas-PL, Camellin–Calossi, and OKULIX ray tracing software. We compared the median values of the arithmetic and absolute prediction errors among the five formulas. Results: The median arithmetic errors after cataract surgery for the five formulas were 0.70 D (diopter) (range −0.41 to 2.78), −0.96 D (range −2.14 to 0.81), −0.81 D (range −1.89 to 1.15), −0.04 D (range −1.35 to 1.47), and 0.68 D (range −0.61 to 2.50), respectively. Conclusion: The Camellin–Calossi formula is a good option for calculating IOL powers in eyes that underwent PTK.

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特集エイジングと加齢眼疾患４.エイジングからみた強度近視

鳥居秀成

眼科 (金原出版) 58 ( 6 ) 635 - 641 2016.06

Lead author, Last author, Corresponding author, ISSN 00164488

Laser in situ keratomileusis(LASIK)後白内障手術の眼内レンズ度数計算式の精度

堀祥子, 根岸一乃, 佐伯めぐみ, 増井佐千子, 鳥居秀成, 西恭代, 常吉由佳里, 坪田一男

IOL & RS ((株)杏林舎内「IOL&RS」編集事務局) 30 ( 2 ) 232 - 237 2016.06

Lead author, Last author, Corresponding author, ISSN 1341-3678

目的:OKULIX(OK)、A-P法(A-P)、Shammas-PL式(S)、Haigis-L式(H-L)、Iida-Shimizu method(I-S)の5式を用いて、laser in situ keratomileusis(LASIK)後の白内障手術における眼内レンズ(IOL)度数計算の精度を比較する。方法:LASIK術後に白内障手術を行い、術後1ヵ月以上経過観察できた28例36眼で、前述のIOL計算式による術後屈折誤差を後方視的に比較した。結果:術後屈折誤差(算術値)の中央値(D)はOK、A-P、S、H-L、I-Sの順に0.00、0.48、-0.69、-0.83、-0.33でSおよびH-Lは他よりも近視寄りだった(P<0.01)。術後屈折誤差が±1.0D以内の割合(%)は、同順に83.3、80.6、76.0、60.0、86.1であり、±1.0D以内の割合はH-LがOK、I-Sよりも低かった(P<0.05)。結論:計算式によって屈折誤差の分布は異なる。LASIK術後のIOL度数決定の際には各計算式による誤差の特徴も考慮すべきである。(著者抄録)

トーリック眼内レンズ移植に対する3つのマーキング法の臨床成績の比較(Comparison of clinical outcomes among 3 marking methods for toric intraocular lens implantation)

Onishi Hideyuki, Torii Hidemasa, Watanabe Kazuhiro, Tsubota Kazuo, Negishi Kazuno

Japanese Journal of Ophthalmology (シュプリンガー・ジャパン(株)) 60 ( 3 ) 142 - 149 2016.05

Lead author, Last author, Corresponding author, ISSN 0021-5155

白内障手術を施行した48名(平均67.5歳)48眼を対象に、トーリック眼内レンズ(IOL)の位置に関する回転誤差と3つのマーキング法での視機能や屈折に関する成績を比較し、トーリックIOL挿入のためのマニュアルでのマーキング法について評価した。マーキング法は虹彩パターンマーキング法(虹彩パターン群)、振り子マーキング法(振り子群)、3点マーキング法(3点群)の3つを用いた。その結果、回転誤差は虹彩パターン群4.0±3.1°、振り子群5.3±4.1°、3点群7.3±6.0°で、虹彩パターン群が3点群に比べて有意に小さかった。虹彩パターン群と振り子群の間には有意差はなかった。術後の未補正距離視力と乱視の差は3群間で有意差はなかった。3点マーキング法を用いるトーリックIOL移植の屈折と視機能の成績は他の2つの方法と同等であったが、軸の位置の精度は虹彩パターン法と比較して有意に低かった。

Comparison of clinical outcomes among 3 marking methods for toric intraocular lens implantation

Onishi Hideyuki, Torii Hidemasa, Watanabe Kazuhiro, Tsubota Kazuo, Negishi Kazuno

Japanese Journal of Ophthalmology (Japanese Journal of Ophthalmology) 60 ( 3 ) 1 - 8 2016.03

ISSN 0021-5155

Purpose: To compare the clinical outcomes of 3 marking methods for toric intraocular lens (IOL) implantation in cataract patients. Methods: This study included 48 eyes of 48 cataract patients who underwent cataract surgery with toric IOL implantation. The rotational errors of 3 marking methods—the iris pattern marking method (iris pattern group), the pendulum marking method (pendulum group), and the 3-point marking method (3-point group)—were assessed. Results: The respective rotational errors were 4.0° ± 3.1° (mean ± SD), 5.3° ± 4.1°, and 7.3° ± 6.0°. The iris pattern group had significantly (P = 0.048) smaller rotational errors than did the 3-point group; no significant difference was found between the iris pattern and pendulum groups. However, the differences in postoperative uncorrected distance visual acuity and astigmatism did not reach significance among the 3 groups. Conclusion: The refractive and visual results of toric IOL implantation using the 3-point marking method were comparable to the other methods evaluated in this study, although the accuracy of the axis alignment of the toric IOLs was significantly lower than that obtained with the iris pattern method.

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Functional visual acuity of early presbyopia

Katada Yusaku, Negishi Kazuno, Watanabe Kazuhiro, Shigeno Yuta, Saiki Megumi, Torii Hidemasa, Kaido Minako, Tsubota Kazuo

PLoS One (PLoS ONE) 11 ( 3 ) 2016.03

ISSN 1932-6203

Purpose: To evaluate visual function in patients with early presbyopia using the functional visual acuity (FVA) test. Methods: This study included 27 eyes of 27 healthy older volunteers (mean age, 44.1 ± 2.6 years) and 14 eyes of 14 healthy young volunteers (mean age, 28.4±4.8 years). The distance-corrected visual acuity (DCVA), distance-corrected near VA (DCNVA), subjective amplitude of accommodation (AA), and distance and near pupillary diameters were measured. The distance FVA and distance-corrected near FVA (DCNFVA) were measured using the FVA Measurement System. The standard Schirmer test and standard tear break-up time measurement also were performed. Results: The logarithm of the minimum angle of resolution (logMAR) DCVA was better than 0 in all subjects. The percentages of subjects with logMAR DCNVA below 0 was significantly lower in the presbyopia group than in the young group. The DCNFVA in the presbyopia group was significantly (P <0.001) poorer than the DCNVA in that group. Significant linear negative correlations were seen between the DCNVA and AA (r = -0.507, P <0.001) and the DCNFVA and AA (r = -0.681, P <0.001) in the older subjects. Stepwise regression analysis showed that only the AA was a significant factor predictive of the DCNFVA in the presbyopia group. Tear function parameters were not adopted in the regression model. Conclusions: Measurement of the DCNFVA can detect decreased AA in early presbyopia better than measurement of the conventional near VA. The DCNFVA is a good index for early presbyopia.

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Effect of neodymium

Yotsukura Erisa, Torii Hidemasa, Saiki Megumi, Negishi Kazuno, Tsubota Kazuo

Journal of Cataract and Refractive Surgery 42 ( 3 ) 399 - 404 2016.03

ISSN 0886-3350

Purpose To evaluate the effect of neodymium:YAG (Nd:YAG) laser capsulotomy on the visual function in patients with posterior capsule opacification (PCO) and good visual acuity. Setting Keio University Hospital, Tokyo, Japan. Design Observational case series. Methods Eyes were evaluated that had previous cataract surgery with a clinical diagnosis of PCO requiring Nd:YAG laser capsulotomy regardless of a good corrected distance visual acuity (CDVA) (at least 20/20). The CDVA, 10% low contrast visual acuity (LCVA), wavefront aberrations from the 3rd to 6th order, and retinal straylight were measured before and after Nd:YAG laser capsulotomy. Results The study included 16 eyes of 16 patients (10 men, 6 women; mean age 69.5 years ± 9.3 [SD]). The mean CDVA, LCVA, and straylight after Nd:YAG laser capsulotomy improved significantly (P <.05). The root mean square (RMS) of the 3rd Zernike coefficients (S3) and the RMS of the total higher-order aberrations (HOAs) from the 3rd to 6th order decreased significantly after capsulotomy (P <.05). The straylight correlated significantly with the total HOAs (r = 0.727, P = .002) and S3 (r = 0.748, P = .001) before capsulotomy. Subjective symptoms resolved after capsulotomy in all cases. Conclusions Neodymium:YAG laser capsulotomy enabled a significant improvement in visual function even in patients with PCO with good visual acuity. Straylight measurements might be useful to determine the indications for Nd:YAG laser capsulotomy when patients report visual disturbances without decreased visual acuity.

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Effect of neodymium: YAG laser capsulotomy on visual function in patients with posterior capsule opacification and good visual acuity

E Yotsukura, H Torii, M Saiki, K Negishi, K Tsubota

Journal of Cataract & Refractive Surgery 42 (3), 399-404 (Journal of Cataract and Refractive Surgery) 42 ( 3 ) 399 - 404 2016.03

Lead author, Last author, Corresponding author, ISSN 08863350

Purpose To evaluate the effect of neodymium:YAG (Nd:YAG) laser capsulotomy on the visual function in patients with posterior capsule opacification (PCO) and good visual acuity. Setting Keio University Hospital, Tokyo, Japan. Design Observational case series. Methods Eyes were evaluated that had previous cataract surgery with a clinical diagnosis of PCO requiring Nd:YAG laser capsulotomy regardless of a good corrected distance visual acuity (CDVA) (at least 20/20). The CDVA, 10% low contrast visual acuity (LCVA), wavefront aberrations from the 3rd to 6th order, and retinal straylight were measured before and after Nd:YAG laser capsulotomy. Results The study included 16 eyes of 16 patients (10 men, 6 women; mean age 69.5 years ± 9.3 [SD]). The mean CDVA, LCVA, and straylight after Nd:YAG laser capsulotomy improved significantly (P < .05). The root mean square (RMS) of the 3rd Zernike coefficients (S3) and the RMS of the total higher-order aberrations (HOAs) from the 3rd to 6th order decreased significantly after capsulotomy (P < .05). The straylight correlated significantly with the total HOAs (r = 0.727, P = .002) and S3 (r = 0.748, P = .001) before capsulotomy. Subjective symptoms resolved after capsulotomy in all cases. Conclusions Neodymium:YAG laser capsulotomy enabled a significant improvement in visual function even in patients with PCO with good visual acuity. Straylight measurements might be useful to determine the indications for Nd:YAG laser capsulotomy when patients report visual disturbances without decreased visual acuity.

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Abstracts from the 15th International Myopia Conference

A Benavente-Perez, A Nour, T Ansel, K Abarr, L Yan, K Roden, D Troilo, ...

Eye and Vision 3 (1), 1-11 2016