Details of a Researcher - Aoki, Daisuke

Papers - Aoki, Daisuke

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Final report of the Committee on Gynecologic Oncology, the Japan Society of Obstetrics and Gynecology, on a fact-finding questionnaire on the status of treatment of hereditary breast and ovarian cancer syndrome in Japan

Satoh T, Takamatsu K, Takeshima N, Kobayashi H, Aoki D, Suzuki N

J Obstet Gynaecol Res 43 ( 9 ) 1377 - 1380 2017.09

Research paper (scientific journal), Joint Work

New use of microsatellite instability analysis in endometrial cancer

Kunitomi, H., Banno, K., Yanokura, M., Takeda, T., Iijima, M., Nakamura, K., Iida, M., Adachi, M., Watanabe, K., Matoba, Y., Kobayashi, Y., Tominaga, E. and Aoki, D.

Oncol Lett 14 ( 3 ) 3297 - 3301 2017.09

Research paper (scientific journal), Joint Work, ISSN 1792-1074

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A Comparison of Dye Versus Fluorescence Methods for Sentinel Lymph Node Mapping in Endometrial Cancer

Yamagami, W., Susumu, N., Kataoka, F., Makabe, T., Sakai, K., Ninomiya, T., Wada, M., Nomura, H., Hirasawa, A., Banno, K., Nakahara, T., Kameyama, K. and Aoki, D.

Int J Gynecol Cancer 27 ( 7 ) 1517 - 1524 2017.09

Research paper (scientific journal), Joint Work, ISSN 1048-891X

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治療薬解説　PARP阻害薬

AOKI DAISUKE

カレントテラピー 35 ( 9 ) 74 - 77 2017.09

Drug repositioning of mevalonate pathway inhibitors as antitumor agents for ovarian cancer

Kobayashi Y, Kashima H, Rahmanto YS, Banno K, Yu Y, Matoba Y, Watanabe K, Iijima M, Takeda T, Kunitomi H, Iida M, Adachi M, Nakamura K, Tsuji K, Masuda K, Nomura H, Tominaga E, Aoki D

Oncotarget 8 ( 42 ) 72147 - 72156 2017.09

Research paper (scientific journal), Joint Work

Whole-genome sequencing revealed novel prognostic biomarkers and promising targets for therapy of ovarian clear cell carcinoma

Itamochi, H., Oishi, T., Oumi, N., Takeuchi, S., Yoshihara, K., Mikami, M., Yaegashi, N., Terao, Y., Takehara, K., Ushijima, K., Watari, H., Aoki, D., Kimura, T., Nakamura, T., Yokoyama, Y., Kigawa, J. and Sugiyama, T.

Br J Cancer 117 ( 5 ) 717 - 724 2017.08

Research paper (scientific journal), Joint Work, ISSN 0007-0920

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Recent advances in the molecular mechanisms of Mayer-Rokitansky-Kuster-Hauser syndrome

Watanabe, K., Kobayashi, Y., Banno, K., Matoba, Y., Kunitomi, H., Nakamura, K., Adachi, M., Umene, K., Kisu, I., Tominaga, E. and Aoki, D.

Biomed Rep 7 ( 2 ) 123 - 127 2017.08

Research paper (scientific journal), Joint Work, ISSN 2049-9434

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遺伝性卵巣がん

AOKI DAISUKE

成人病と生活習慣病 47 ( 7 ) 861 - 866 2017.07

Joint Work

手術前禁忌薬（経口避妊薬、低用量エストロゲン－プロゲスチン配合薬）に関する医療安全対策

AOKI DAISUKE

東京産科婦人科学会会誌 66 ( 3 ) 424 - 428 2017.07

Research paper (scientific journal), Joint Work

Comparison Between Laparoscopy and Laparotomy in Systematic Para-Aortic Lymphadenectomy for Patients with Endometrial Cancer: A Retrospective Multicenter Study

Tanaka, T., Terai, Y., Hayashi, S., Aoki, D., Miki, M., Kobayashi, E., Kimura, T., Baba, T., Matsumura, N. and Ohmichi, M.

J Gynecol Surg 33 ( 3 ) 105 - 110 2017.06

Research paper (scientific journal), Joint Work, ISSN 1042-4067

Objective: Laparoscopic surgery has been developed worldwide due to its minimal invasion as well as noninferiority, compared with laparotomy. However, whether or not laparoscopic systematic para-aortic lymphadenectomy for endometrial cancer is feasible and has advantages of various clinical factors, such as a short hospital stay, less blood loss, and faster recovery, compared with open surgery has not yet been clarified. The aim of this study was to compare a laparoscopic procedure with laparotomy for para-aortic lymphadenectomy for patients with endometrial cancer. Study Design: This was a retrospective multicenter study of laparoscopic systematic para-aortic lymphadenectomy for endometrial cancer in five institutions. Materials and Methods: The current authors conducted a retrospective multicenter study of laparoscopic systematic para-aortic lymphadenectomy for endometrial cancer. The study involved patients from five institutions in Japan between January 2008 and March 2016. Clinical data were compared with those of a laparotomic procedure performed around the same period. Results: A total of 54 patients in the laparoscopic group and 99 patients in the laparotomic group were analyzed. In the laparoscopic group, 21 patients had stage IA disease, 19 had stage IB disease, 5 had stage II disease, and 9 had stage III disease. In the laparotomic group, 35 patients had stage IA disease, 19 had stage IB disease, 9 had stage II disease, and 36 had stage III disease. There were no significant differences in characteristics between the groups, including age, body mass index, and histologic type. The mean operative time in the laparoscopic group was 483 +/- 102 minutes, while that in the laparotomic group was 481 +/- 106 minutes (p = 0.9). The laparoscopic group had less intraoperative blood loss (143 +/- 253 versus 988 +/- 694 mL; p < 0.01) and shorter hospital stays (8.4 +/- 5.7 versus 16.1 +/- 8.0 days; p < 0.01). The rates of intraoperative complications were not significantly different between the groups. No cases of ileus occurred in the laparoscopic group. Procedures for 2 of the 54 patients in the laparoscopic group were converted to laparotomy. The number of dissected pelvic lymph nodes (31.8 +/- 10.1 versus 39.9 +/- 15.9, p < 0.01) and para-aortic lymph nodes (26.2 +/- 10.9 versus 31.1 +/- 13.2; p = 0.02) were lower in the laparoscopic group than in the laparotomic group. The postoperative minimum level of hemoglobin was higher in the laparoscopic group than in the laparotomic group (10.4 +/- 1.1 g/dL versus 9.9 +/- 1.4 g/dL; p = 0.02). In contrast, the postoperative maximum level of C-reactive protein was lower in the laparoscopic group than in the laparotomic group (6.3 +/- 3.8 mg/dL versus 10.2 +/- 4.9 mg/dL; p < 0.01). The recurrence rate was not significantly different between the groups in the above time period (7.4% versus 14.3%; p = 0.2). Conclusions: Laparoscopic systematic para-aortic lymphadenectomy is feasible and can be substituted for laparotomic procedures for patients with early stage endometrial cancer. ( J GYNECOL SURG 33:105).

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遺伝性乳癌卵巣癌症候群と女性ヘルスケア

AOKI DAISUKE

更年期と加齢のヘルスケア 16 ( 1 ) 42 - 45 2017.06

Joint Work

Genome-wide DNA methylation sequencing reveals miR-663a is a novel epimutation candidate in CIMP-high endometrial cancer

Yanokura, M., Banno, K., Adachi, M., Aoki, D. and Abe, K.

Int J Oncol 50 ( 6 ) 1934 - 1946 2017.06

Research paper (scientific journal), Joint Work, ISSN 1019-6439

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医療機器に生じたトラブル

AOKI DAISUKE

産婦人科の実際 66 ( 6 ) 767 - 771 2017.06

Joint Work

Clinical utility of a self-administered questionnaire for assessment of hereditary gynecologic cancer

Masuda, K., Hirasawa, A., Irie-Kunitomi, H., Akahane, T., Ueki, A., Kobayashi, Y., Yamagami, W., Nomura, H., Kataoka, F., Tominaga, E., Banno, K., Susumu, N. and Aoki, D.

Jpn J Clin Oncol 47 ( 5 ) 473 2017.05

Research paper (scientific journal), Joint Work, ISSN 0368-2811

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Clinical utility of a self-administered questionnaire for assessment of hereditary gynecologic cancer

Masuda, K., Hirasawa, A., Irie-Kunitomi, H., Akahane, T., Ueki, A., Kobayashi, Y., Yamagami, W., Nomura, H., Kataoka, F., Tominaga, E., Banno, K., Susumu, N. and Aoki, D.

Jpn J Clin Oncol 47 ( 5 ) 401 - 406 2017.05

Research paper (scientific journal), Joint Work, ISSN 0368-2811