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Papers - Sato, Kazuki

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Seabird Biologging System with Compact Waterproof Airflow Sensor

Takahashi, H; Naruoka, M; Inada, Y; Sato, K

JOURNAL OF ROBOTICS AND MECHATRONICS 33 ( 3 ) 466 - 474 2021.06

ISSN 0915-3942

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Predictors of residual low back pain after acute osteoporotic compression fracture

Inose, H; Kato, T; Ichimura, S; Nakamura, H; Hoshino, M; Togawa, D; Hirano, T; Tokuhashi, Y; Ohba, T; Haro, H; Tsuji, T; Sato, K; Sasao, Y; Takahata, M; Otani, K; Momoshima, S; Yuasa, M; Hirai, T; Yoshii, T; Okawa, A

JOURNAL OF ORTHOPAEDIC SCIENCE 26 ( 3 ) 453 - 458 2021.05

ISSN 0949-2658

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Causes of Procedural Failures of Closed Reductions using an Extension-Block Pin for Bony Mallet Finger

Suzuki T., Iwamoto T., Matsumura N., Kimura H., Nakamura M., Matsumoto M., Sato K.

Journal of Hand and Microsurgery (Journal of Hand and Microsurgery) 13 ( 2 ) 69 - 74 2021.04

ISSN 09743227

This retrospective study evaluated procedural failures of closed reductions using an extension-block Kirschner wire (K-wire) for bony mallet finger. A total of 132 patients who underwent a closed reduction for bony mallet finger in a procedure using an extension-block K-wire were radiographically assessed. Radiographs were used to evaluate (1) postoperative displacement of the reduction before or after K-wire removal and (2) inaccurate reduction of the fragment immediately after surgery. The causes of procedural failure and bone union were evaluated using radiographs and medical records of the intraoperative findings. Out of 132 patients, 17 with procedural failure were enrolled. Displacement of the reduction before and after K-wire removal occurred in seven and six cases, respectively. Inaccurate reduction immediately after surgery occurred in four cases. The most common cause of procedural failure was inaccurate insertion of the K-wire to fix the distal interphalangeal joint (eight cases) followed by inaccurate insertion of the extension-block pin (five cases). All patients had bone union regardless of the displacement of the reduction or inaccurate reduction of the fragment. Caution should be exercised during the reduction and fixation when an extension-block K-wire is used in a closed reduction procedure.

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Development of a microsurgery-assisted robot for high-precision thread traction and tension control, and confirmation of its applicability

Hangai S., Nozaki T., Soma T., Miyashita H., Asoda S., Yazawa M., Sato K., Kawana H., Ohnishi K., Kobayashi E.

International Journal of Medical Robotics and Computer Assisted Surgery (International Journal of Medical Robotics and Computer Assisted Surgery) 17 ( 2 ) 2021.04

ISSN 14785951

Background: Microsurgery requires high skills for suturing using fragile threads, often within narrow surgical fields. Precise tension is required for good healing and to avoid the risk of thread breakage. Methods: To meet the demands, we developed a novel assist robot utilizing high-precision sensorless haptic technology. The robot adopts a cable-driven mechanism to maintain a distance from the surgical area and enhances compatibility with surgical equipment such as microscopes. The robot performance was verified through in vitro and in vivo experiments using a rat model. Results: The realization of precise tension control was confirmed in both experiments. In particular, in the in vivo experiments, the developed robot succeeded to produce a knot with an accurate tension of 0.66% error. Conclusions: The developed robot can realize to control traction force precisely. This technology might open up the window for a full assist robot for microsurgery with haptic feeling.

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Defining a good death for people with dementia: A scoping review

Takahashi, Z; Yamakawa, M; Nakanishi, M; Fukahori, H; Igarashi, N; Aoyama, M; Sato, K; Sakai, S; Nagae, H; Miyashita, M

JAPAN JOURNAL OF NURSING SCIENCE 18 ( 2 ) e12402 2021.04

ISSN 1742-7932

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Personal View つれづれの時

佐藤和毅

整形・災害外科 (金原出版) 64 ( 3 ) 245 - 245 2021.03

ISSN 03874095

Risk Factors Contributing to Early Implant Fracture in Silicone Metacarpophalangeal Joint Arthroplasty for Patients With Rheumatoid Arthritis

Iwamoto T., Ishii K., Suzuki T., Kimura H., Matsumura N., Sato K.

Journal of Hand Surgery (Journal of Hand Surgery) 46 ( 3 ) 243.e1 - 243.e7 2021.03

ISSN 03635023

Purpose: To identify the risk factors associated with early implant fracture of silicone metacarpophalangeal (MCP) joint arthroplasty using the volar hinge silicone implant for patients with rheumatoid arthritis. Methods: We retrospectively reviewed 113 fingers of 31 hands that underwent MCP joint arthroplasty between 2008 and 2014, with a minimum follow-up of 3 years,. An implant fracture within 3 years after surgery was regarded as an early implant fracture. Patient records were reviewed for potential risk factors of age, affected fingers, ulnar drift angle, and range of motion of the MCP joint before surgery and 1 year after surgery. Candidate risk factors were compared at the level of the digit and at the patient level. Results: With fracture of the implants as the end point, Kaplan–Meier estimated survival rate was 74.3% at 3 years and 67.9% at 5 years. Early implant fracture was detected in 29 fingers. Bivariate analyses showed significant associations between early implant fracture and MCP joint arc of motion before surgery, MCP joint flexion range 1 year after surgery, and MCP joint arc of motion 1 year after surgery. Multiple logistic regression analysis showed that increased MCP joint flexion range 1 year after surgery was an independent risk factor for early implant fracture. Conclusions: Increasing MCP joint flexion range was associated with increased fractures of the implants. We propose that the MCP joint flexion range should be restricted to less than 60° in postoperative rehabilitation; it is necessary to educate the patient to permanently avoid excessive flexion of the MCP joint. Type of study/level of evidence: Therapeutic IV.

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A Web Server for Designing Molecular Switches Composed of Two Interacting RNAs

Taneda, A; Sato, K

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 ( 5 ) 2021.03

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Treatment with an active vitamin D analogue blocks hypothalamic dysfunction-induced bone loss in mice

Ito E., Sato Y., Kobayashi T., Nakamura S., Kaneko Y., Soma T., Matsumoto T., Kimura A., Miyamoto K., Matsumoto H., Matsumoto M., Nakamura M., Sato K., Miyamoto T.

Biochemical and Biophysical Research Communications (Biochemical and Biophysical Research Communications) 542 48 - 53 2021.02

ISSN 0006291X

Estrogen deficiency can be caused by ovarian dysfunction in females. Mechanisms underlying osteoporosis in this condition have been characterized in animal models, such as ovariectomized mice and rats, although it remains unclear how hypothalamic dysfunction promotes osteoporosis. Here, we show that administration of a gonadotropin-releasing hormone antagonist (GnRHa) significantly decreases uterine weight, a manifestation of hypothalamic dysfunction, and promotes both cortical and trabecular bone loss in female mice in vivo. We also report that osteoclast number significantly increased in mice administered GnRHa, and that the transcription factor hypoxia inducible factor 1 alpha (HIF1α) accumulated in those osteoclasts. We previously reported that treatment of mice with the active vitamin D analogue ED71, also known as eldecalcitol, inhibited HIF1α accumulation in osteoclasts. We show here that in mice, co-administration of ED71 with GnRHa significantly rescued the reduced cortical and trabecular bone mass promoted by GnRHa administration alone. GnRHa-dependent HIF1α accumulation in osteoclasts was also blocked by co-administration of ED71. We conclude that hypothalamic dysfunction promotes HIF1α accumulation in osteoclasts and likely results in reduced bone mass. We conclude that treatment with ED71 could serve as a therapeutic option to counter osteoporotic conditions in humans.

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RNA secondary structure prediction using deep learning with thermodynamic integration

Sato, K; Akiyama, M; Sakakibara, Y

NATURE COMMUNICATIONS 12 ( 1 ) 941 2021.02

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Experimental evaluation of the GE Discovery 870 CZT clinical SPECT system equipped with WEHR and MEHRS collimator

Ito, T; Matsusaka, Y; Onoguchi, M; Ichikawa, H; Okuda, K; Shibutani, T; Shishido, M; Sato, K

JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS 22 ( 2 ) 165 - 177 2021.02

ISSN 1526-9914

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A hypomorphic variant in EYS detected by genome-wide association study contributes toward retinitis pigmentosa

Nishiguchi, KM; Miya, F; Mori, Y; Fujita, K; Akiyama, M; Kamatani, T; Koyanagi, Y; Sato, K; Takigawa, T; Ueno, S; Tsugita, M; Kunikata, H; Cisarova, K; Nishino, J; Murakami, A; Abe, T; Momozawa, Y; Terasaki, H; Wada, Y; Sonoda, KH; Rivolta, C; Tsunoda, T; Tsujikawa, M; Ikeda, Y; Nakazawa, T

COMMUNICATIONS BIOLOGY 4 ( 1 ) 140 2021.01

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Neutron-antineutron oscillation search using a 0.37 megaton-years exposure of Super-Kamiokande

Abe, K; Bronner, C; Hayato, Y; Ikeda, M; Imaizumi, S; Ito, H; Kameda, J; Kataoka, Y; Miura, M; Moriyama, S; Nagao, Y; Nakahata, M; Nakajima, Y; Nakayama, S; Okada, T; Okamoto, K; Orii, A; Pronost, G; Sekiya, H; Shiozawa, M; Sonoda, Y; Suzuki, Y; Takeda, A; Takemoto, Y; Takenaka, A; Tanaka, H; Yano, T; Akutsu, R; Han, S; Kajita, T; Okumura, K; Tashiro, T; Wang, R; Xia, J; Bravo-Berguño, D; Labarga, L; Marti, LL; Zaldivar, B; Blaszczyk, FDM; Kearns, E; Gustafson, JD; Raaf, JL; Stone, JL; Wan, L; Wester, T; Bian, J; Griskevich, NJ; Kropp, WR; Locke, S; Mine, S; Smy, MB; Sobel, HW; Takhistov, V; Weatherly, P; Hill, J; Kim, JY; Lim, IT; Park, RG; Bodur, B; Scholberg, K; Walter, CW; Coffani, A; Drapier, O; El Hedri, S; Giampaolo, A; Gonin, M; Mueller, TA; Paganini, P; Quilain, B; Ishizuka, T; Nakamura, T; Jang, JS; Learned, JG; Anthony, LHV; Sztuc, AA; Uchida, Y; Berardi, V; Catanesi, MG; Radicioni, E; Calabria, NF; Machado, LN; De Rosa, G; Collazuol, G; Iacob, F; Lamoureux, M; Ospina, N; Ludovici, L; Nishimura, Y; Cao, S; Friend, M; Hasegawa, T; Ishida, T; Kobayashi, T; Matsubara, T; Nakadaira, T; Jakkapu, M; Nakamura, K; Oyama, Y; Sakashita, K; Sekiguchi, T; Tsukamoto, T; Nakano, Y; Shiozawa, T; Suzuki, AT; Takeuchi, Y; Yamamoto, S; Ali, A; Ashida, Y; Feng, J; Hirota, S; Ichikawa, AK; Kikawa, T; Mori, M; Nakaya, T; Wendell, RA; Yasutome, K; Fernandez, P; McCauley, N; Mehta, P; Pritchard, A; Tsui, KM; Fukuda, Y; Itow, Y; Menjo, H; Niwa, T; Sato, K; Tsukada, M; Mijakowski, P; Posiadala-Zezula, M; Jung, CK; Vilela, C; Wilking, MJ; Yanagisawa, C; Harada, M; Hagiwara, K; Horai, T; Ishino, H; Ito, S; Koshio, Y; Ma, W; Piplani, N; Sakai, S; Kuno, Y; Barr, G; Barrow, D; Cook, L; Goldsack, A; Samani, S; Simpson, C; Wark, D; Nova, F; Boschi, T; Di Lodovico, F; Sedgwick, SM; Taani, M; Zsoldos, S; Yang, JY; Jenkins, SJ; McElwee, JM; Thiesse, MD; Thompson, LF; Malek, M; Stone, O; Okazawa, H; Kim, SB; Yu, I; Nishijima, K; Koshiba, M; Ogawa, N; Iwamoto, K; Yokoyama, M; Martens, K; Vagins, MR; Kuze, M; Izumiyama, S; Tanaka, M; Yoshida, T; Inomoto, M; Ishitsuka, M; Matsumoto, R; Ohta, K; Shinoki, M; Martin, JF; Tanaka, HA; Towstego, T; Hartz, M; Konaka, A; de Perio, P; Prouse, NW; Pointon, BW; Chen, S; Xu, BD; Richards, B; Jamieson, B; Walker, J; Minamino, A; Okamoto, K; Pintaudi, G; Sasaki, R

PHYSICAL REVIEW D 103 ( 1 ) 2021.01

ISSN 2470-0010

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Food restriction reduces cortical bone mass and serum insulin-like growth factor-1 levels and promotes uterine atrophy in mice

Ito E., Sato Y., Kobayashi T., Nakamura S., Kaneko Y., Soma T., Matsumoto T., Kimura A., Miyamoto K., Matsumoto H., Matsumoto M., Nakamura M., Sato K., Miyamoto T.

Biochemical and Biophysical Research Communications (Biochemical and Biophysical Research Communications) 534 165 - 171 2021.01

ISSN 0006291X

Low energy availability in female athletes often causes hypothalamic amenorrhea and osteoporosis, in turn promoting stress fractures. Mechanisms underlying these conditions remain unclear. Here we show that model mice subjected to food restriction (FR) or FR-plus-voluntary running exercise exhibit significantly reduced bone mineral density, cortical bone parameters and uterine weight than do control mice, and that these parameters worsen in the FR-plus-exercise group. Relative to controls, FR and FR-plus-exercise groups showed significantly lower mineral apposition rate and osteoclast number and significantly reduced serum insulin-like growth factor-1 (IGF1) levels. Outcomes were rescued by ED71 or 1.25(OH)2D3 treatment. Thus, we conclude that administration of active vitamin D analogues represents a possible treatment to prevent these conditions.

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Occupational exposure limits for acetaldehyde, 2-bromopropane, glyphosate, manganese and inorganic manganese compounds, and zinc oxide nanoparticle, and the biological exposure indices for cadmium and cadmium compounds and ethylbenzene, and carcinogenicity, occupational sensitizer, and reproductive toxicant classifications

Araki, A; Azuma, K; Endo, G; Endo, Y; Fukushima, T; Hara, K; Harada, K; Hori, H; Horie, S; Horiguchi, H; Ichiba, M; Ichihara, G; Ishitake, T; Ito, A; Ito, Y; Iwasawa, S; Kakamu, T; Kamijima, M; Karita, K; Kawai, T; Kawamoto, T; Kishi, R; Kumagai, S; Matsumoto, A; Miyagawa, M; Miyauchi, H; Morimoto, Y; Nagano, K; Naito, H; Nakajima, T; Nakano, M; Nomiyama, T; Okuda, H; Okuda, M; Omae, K; Sato, K; Sobue, T; Suwazono, Y; Takebayashi, T; Takeshita, T; Takeuchi, A; Takeuchi, A; Tanaka, S; Tsuji, M; Tsukahara, T; Ueno, S; Ueyama, J; Umeda, Y; Yamamoto, K; Yamano, Y; Yamauchi, T; Yano, E

JOURNAL OF OCCUPATIONAL HEALTH 63 ( 1 ) 2021.01

ISSN 1341-9145

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Predictors for quality of life improvement after acute osteoporotic vertebral fracture: results of post hoc analysis of a prospective randomized study

Inose, H; Kato, T; Nakamura, H; Hoshino, M; Togawa, D; Hirano, T; Tokuhashi, Y; Ohba, T; Haro, H; Tsuji, T; Sato, K; Sasao, Y; Takahata, M; Otani, K; Momoshima, S; Takahashi, K; Yuasa, M; Hirai, T; Yoshii, T; Okawa, A

QUALITY OF LIFE RESEARCH 30 ( 1 ) 129 - 135 2021.01

ISSN 0962-9343

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A Channel Selection Algorithm Using Reinforcement Learning for Mobile Devices in Massive IoT System

Furukawa, H; Li, AH; Shoji, Y; Watanabe, Y; Kim, SJ; Sato, K; Andreopoulos, Y; Hasegawa, M

2021 IEEE 18TH ANNUAL CONSUMER COMMUNICATIONS & NETWORKING CONFERENCE (CCNC) 2021

ISSN 2331-9852

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Clinical results of open surgery for medial epicondylitis

Suzuki Taku, Hayakawa Katsuhiko, Nakane Takashi, Takeya Hiroaki, Kimura Hiroo, Sato Kazuki, Iwamoto Takuji

Journal of Japan Elbow Society (Japan Elbow Society) 28 ( 2 ) 148 - 149 2021

ISSN 13497324

目的：上腕骨内側上顆炎に対する直視下手術の成績について報告する． 対象と方法：保存加療に抵抗性の上腕骨内側上顆炎に対して直視下手術を施行した7例（男性5例，女性2例，平均年齢54歳）を対象とした．術前に尺骨神経の症状を呈していた症例は5例であった．手術は，全例，屈筋共同腱のデブリドマン，尺骨神経剥離，内側上顆部分切除，内側上顆のドリリングを施行した．評価は，術前，術後1年における疼痛（VAS），握力健側比に関して調査した． 結果：平均VASは術前81（55-100）であったのに対して，術後1年では15（0-40）と有意に低下した．平均握力健側比も術前で 64（26-71）%であったのに対して，最終観察時には 95（84-100）%と有意に改善した． 考察：上腕骨内側上顆炎に対する直視下手術は，有用であった．

Rupture of the lateral collateral ligament of the elbow associated with steroid injection for humeral lateral epicondylitis

Takeya Hiroaki, Suzuki Taku, Kimura Hiroo, Sato Kazuki, Iwamoto Takuji

Journal of Japan Elbow Society (Japan Elbow Society) 28 ( 2 ) 69 - 71 2021

ISSN 13497324

目的：上腕骨外側上顆炎へのステロイド局所注射が原因であると考えられる外側側副靭帯損傷の症例に対して長掌筋腱を用いた靭帯再建術を行い，良好な結果を得たために報告する． 方法：上腕骨外側上顆炎に対してステロイド局所注射後に，外側側副靭帯損傷を生じた3症例（平均年齢52歳，男性3例）を対象とした．評価は，術前注射回数，術後疼痛，不安定性の有無，肘関節自動運動可動域について調査した． 結果：術前注射回数は平均5.3（3～5）回であった．全例で術前に認めていた肘関節外側部痛や不安定性は術後に消失し，可動域制限も認めなかった． 考察：上腕骨外側上顆炎へのステロイド局所注射による外側側副靭帯損傷は注射回数が3回以上を損傷リスクとする報告もある．上腕骨外側上顆炎に対しての多数回のステロイド局所注射は，外側側副靭帯断裂の原因となる可能性があることに留意が必要である．

Effect of volar angulation of extra-articular distal radius fractures on distal radioulnar joint stability

Bessho Y., Nakamura T., Nagura T., Nishiwaki M., Sato K., Toyama Y.

Journal of Hand Surgery: European Volume 40 ( 8 ) 775 - 782 2015.10

ISSN 1753-1934

The relationship between increased volar tilt of the distal radius and distal radioulnar joint stability was examined. Distal radioulnar joint stiffness was recorded at 10° intervals from 10° dorsal angulation to 20° of volar angulation from the anatomical position of the radius. Tests were performed with the intact radioulnar ligament and repeated after partial and then complete sectioning of the radioulnar ligament at the ulnar fovea. With the intact radioulnar ligament, distal radioulnar joint stiffness increased significantly at 10° and 20° of volar angulation. Partial sectioning of the radioulnar ligament resulted in an approximate 10% decrease of distal radioulnar joint stiffness compared with the intact state, but distal radioulnar joint stiffness still increased significantly with greater volar tilt. Complete sectioning of the radioulnar ligament significantly decreased distal radioulnar joint stiffness, and increasing the volar tilt did not result in increased distal radioulnar joint stiffness. These results suggest that volar angulation deformities of the distal radius should be corrected to 10° of volar tilt when the triangular fibrocartilage complex is intact.

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