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Papers - Sato, Kazuki

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Treadmill Training for Common Marmoset to Strengthen Corticospinal Connections After Thoracic Contusion Spinal Cord Injury.

Kondo T, Saito R, Sato Y, Sato K, Uchida A, Yoshino-Saito K, Shinozaki M, Tashiro S, Nagoshi N, Nakamura M, Ushiba J, Okano H

Frontiers in cellular neuroscience 16 858562 2022

ISSN 1662-5102

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Diffuse supernova neutrino background search at Super-Kamiokande

Abe, K; Bronner, C; Hayato, Y; Hiraide, K; Ikeda, M; Imaizumi, S; Kameda, J; Kanemura, Y; Kataoka, Y; Miki, S; Miura, M; Moriyama, S; Nagao, Y; Nakahata, M; Nakayama, S; Okada, T; Okamoto, K; Orii, A; Pronost, G; Sekiya, H; Shiozawa, M; Sonoda, Y; Suzuki, Y; Takeda, A; Takemoto, Y; Takenaka, A; Tanaka, H; Watanabe, S; Yano, T; Han, S; Kajita, T; Okumura, K; Tashiro, T; Xia, J; Megias, GD; Bravo-Berguño, D; Labarga, L; Marti, L; Zaldivar, B; Pointon, BW; Blaszczyk, FDM; Kearns, E; Raaf, JL; Stone, JL; Wan, L; Wester, T; Bian, J; Griskevich, NJ; Kropp, WR; Locke, S; Mine, S; Smy, MB; Sobel, HW; Takhistov, V; Hill, J; Kim, JY; Lim, IT; Park, RG; Bodur, B; Scholberg, K; Walter, CW; Cao, S; Bernard, L; Coffani, A; Drapier, O; El Hedri, S; Giampaolo, A; Gonin, M; Mueller, TA; Paganini, P; Quilain, B; Ishizuka, T; Nakamura, T; Jang, JS; Learned, JG; Anthony, LHV; Martin, D; Scott, M; Sztuc, AA; Uchida, Y; Berardi, V; Catanesi, MG; Radicioni, E; Calabria, NF; Machado, LN; De Rosa, G; Collazuol, G; Iacob, F; Lamoureux, M; Mattiazzi, M; Ospina, N; Ludovici, L; Maekawa, Y; Nishimura, Y; Friend, M; Hasegawa, T; Ishida, T; Kobayashi, T; Jakkapu, M; Matsubara, T; Nakadaira, T; Nakamura, K; Oyama, Y; Sakashita, K; Sekiguchi, T; Tsukamoto, T; Kotsar, Y; Nakano, Y; Ozaki, H; Shiozawa, T; Suzuki, AT; Takeuchi, Y; Yamamoto, S; Ali, A; Ashida, Y; Feng, J; Hirota, S; Kikawa, T; Mori, M; Nakaya, T; Wendell, RA; Yasutome, K; Fernandez, P; McCauley, N; Mehta, P; Tsui, KM; Fukuda, Y; Itow, Y; Menjo, H; Niwa, T; Sato, K; Tsukada, M; Lagoda, J; Lakshmi, SM; Mijakowski, P; Zalipska, J; Jiang, J; Jung, CK; Vilela, C; Wilking, MJ; Yanagisawa, C; Hagiwara, K; Harada, M; Horai, T; Ishino, H; Ito, S; Kitagawa, H; Koshio, Y; Ma, W; Piplani, N; Sakai, S; Barr, G; Barrow, D; Cook, L; Goldsack, A; Samani, S; Wark, D; Nova, F; Boschi, T; Di Lodovico, F; Gao, J; Migenda, J; Taani, M; Zsoldos, S; Yang, JY; Jenkins, SJ; Malek, M; McElwee, JM; Stone, O; Thiesse, MD; Thompson, LF; Okazawa, H; Kim, SB; Seo, JW; Yu, I; Nishijima, K; Koshiba, M; Iwamoto, K; Nakagiri, K; Nakajima, Y; Ogawa, N; Yokoyama, M; Martens, K; Vagins, MR; Kuze, M; Izumiyama, S; Yoshida, T; Inomoto, M; Ishitsuka, M; Ito, H; Kinoshita, T; Matsumoto, R; Ohta, K; Shinoki, M; Suganuma, T; Ichikawa, AK; Nakamura, K; Martin, JF; Tanaka, HA; Towstego, T; Akutsu, R; Gousy-Leblanc, V; Hartz, M; Konaka, A; de Perio, P; Prouse, NW; Chen, S; Xu, BD; Zhang, Y; Posiadala-Zezula, M; Hadley, D; O'Flaherty, M; Richards, B; Jamieson, B; Walker, J; Minamino, A; Okamoto, K; Pintaudi, G; Sano, S; Sasaki, R

PHYSICAL REVIEW D 104 ( 12 ) 2021.12

ISSN 2470-0010

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Transient alendronate administration to pregnant or lactating mothers prevents bone loss in mice without adverse effects on offspring

Ito E., Sato Y., Kobayashi T., Soma T., Matsumoto T., Kimura A., Miyamoto K., Matsumoto H., Matsumoto M., Nakamura M., Sato K., Miyamoto T.

Bone (Bone) 153 2021.12

ISSN 87563282

Changes in bone metabolism occur in mothers during pregnancy or lactation that may decrease bone mass and result in fragility fractures after partum. However, use of drugs during pregnancy or lactation to counteract these effects is often prohibited or strongly discouraged. Therefore, approaches to protect mothers from fragility fractures have not been established. Here we show that bone mineral density was significantly lower in female mice after partum than in age-matched female mice without partum. We also show that temporary administration of the bisphosphonate alendronate, either just before or just after pregnancy, to female mice was protective against bone loss due to pregnancy or lactation and had no adverse effects on offspring, such as growth retardation. Furthermore, we show that alendronate administration to female mice during lactation was effective in increasing bone mass in mothers without promoting bone abnormalities or growth retardation in offspring. Calcium levels in milk from female mice administered alendronate during lactation were equivalent to those in milk from mothers not treated with alendronate. Overall, we propose that alendronate administration to mothers could prevent bone loss and fragility fractures during pregnancy and lactation.

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A novel device for detecting anaerobic threshold using sweat lactate during exercise

Seki Y., Nakashima D., Shiraishi Y., Ryuzaki T., Ikura H., Miura K., Suzuki M., Watanabe T., Nagura T., Matsumato M., Nakamura M., Sato K., Fukuda K., Katsumata Y.

Scientific Reports (Scientific Reports) 11 ( 1 ) 2021.12

The lactate threshold (LT1), which is defined as the first rise in lactate concentration during incremental exercise, has not been non-invasively and conveniently determined in a clinical setting. We aimed to visualize changes in lactate concentration in sweat during exercise using our wearable lactate sensor and investigate the relationship between the lactate threshold (LT1) and ventilatory threshold (VT1). Twenty-three healthy subjects and 42 patients with cardiovascular diseases (CVDs) were enrolled. During exercise, the dynamic changes in lactate values in sweat were visualized in real-time with a sharp continuous increase up to volitional exhaustion and a gradual decrease during the recovery period. The LT1 in sweat was well correlated with the LT1 in blood and the VT1 (r = 0.92 and 0.71, respectively). In addition, the Bland–Altman plot described no bias between the mean values (mean differences: − 4.5 and 2.5 W, respectively). Continuous monitoring of lactate concentrations during exercise can provide additional information for detecting the VT1.

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Effect of Early vs Delayed Surgical Treatment on Motor Recovery in Incomplete Cervical Spinal Cord Injury With Preexisting Cervical Stenosis A Randomized Clinical Trial

Chikuda, H; Koyama, Y; Matsubayashi, Y; Ogata, T; Ohtsu, H; Sugita, S; Sumitani, M; Kadono, Y; Miura, T; Tanaka, S; Akiyama, T; Ando, K; Anno, M; Azuma, S; Endo, K; Endo, T; Fujiyoshi, T; Furuya, T; Hayashi, H; Higashikawa, A; Hiyama, A; Horii, C; Iimoto, S; Iizuka, Y; Ikuma, H; Imagama, S; Inokuchi, K; Inoue, H; Inoue, T; Ishii, K; Ishii, M; Ito, T; Itoi, A; Iwamoto, K; Iwasaki, M; Kaito, T; Kato, T; Katoh, H; Kawaguchi, Y; Kawano, O; Kimura, A; Kobayashi, K; Koda, M; Komatsu, M; Kumagai, G; Maeda, T; Makino, T; Mannoji, C; Masuda, K; Masuda, K; Matsumoto, K; Matsumoto, M; Matsunaga, S; Matsuyama, Y; Mieda, T; Miyoshi, K; Mochida, J; Moridaira, H; Motegi, H; Nakagawa, Y; Nohara, Y; Oae, K; Ogawa, S; Okazaki, R; Okuda, A; Onishi, E; Ono, A; Oshima, M; Oshita, Y; Saita, K; Sasao, Y; Sato, K; Sawakami, K; Seichi, A; Seki, S; Shigematsu, H; Suda, K; Takagi, Y; Takahashi, M; Takahashi, R; Takasawa, E; Takenaka, S; Takeshita, K; Takeshita, Y; Tokioka, T; Tokuhashi, Y; Tonosu, J; Uei, H; Wada, K; Watanabe, M; Yahata, T; Yamada, K; Yasuda, T; Yasui, K; Yoshii, T

JAMA NETWORK OPEN 4 ( 11 ) e2133604 2021.11

ISSN 2574-3805

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Laminar flow ventilation system to prevent airborne infection during exercise in the COVID-19 crisis: A single-center observational study

Katsumata Y., Sano M., Okawara H., Sawada T., Nakashima D., Ichihara G., Fukuda K., Sato K., Kobayashi E.

PLoS ONE (PLoS ONE) 16 ( 11 November ) 2021.11

Particulate generation occurs during exercise-induced exhalation, and research on this topic is scarce. Moreover, infection-control measures are inadequately implemented to avoid particulate generation. A laminar airflow ventilation system (LFVS) was developed to remove respiratory droplets released during treadmill exercise. This study aimed to investigate the relationship between the number of aerosols during training on a treadmill and exercise intensity and to elucidate the effect of the LFVS on aerosol removal during anaerobic exercise. In this single-center observational study, the exercise tests were performed on a treadmill at Running Science Lab in Japan on 20 healthy subjects (age: 29±12 years, men: 80%). The subjects had a broad spectrum of aerobic capacities and fitness levels, including athletes, and had no comorbidities. All of them received no medication. The exercise intensity was increased by 1-km/h increments until the heart rate reached 85% of the expected maximum rate and then maintained for 10 min. The first 10 subjects were analyzed to examine whether exercise increased the concentration of airborne particulates in the exhaled air. For the remaining 10 subjects, the LFVS was activated during constant-load exercise to compare the number of respiratory droplets before and after LFVS use. During exercise, a steady amount of particulates before the lactate threshold (LT) was followed by a significant and gradual increase in respiratory droplets after the LT, particularly during anaerobic exercise. Furthermore, respiratory droplets ≥0.3 μm significantly decreased after using LFVS (2120800±759700 vs. 560 ± 170, p<0.001). The amount of respiratory droplets significantly increased after LT. The LFVS enabled a significant decrease in respiratory droplets during anaerobic exercise in healthy subjects. This study's findings will aid in exercising safely during this pandemic.

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A Max-Margin Model for Predicting Residue-Base Contacts in Protein-RNA Interactions

Kashiwagi, S; Sato, K; Sakakibara, Y

LIFE-BASEL 11 ( 11 ) 2021.11

ISSN 2075-1729

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Effects of peripheral tears of the triangular fibrocartilage complex on distal radioulnar joint stability: A biomechanical study

Fukuoka M., Nakamura T., Nishiwaki M., Toyama Y., Matsumoto M., Nakamura M., Sato K.

Journal of Orthopaedic Science (Journal of Orthopaedic Science) 26 ( 6 ) 1008 - 1013 2021.11

ISSN 09492658

Background: Peripheral triangular fibrocartilage complex (TFCC) tears may induce instability of the distal radioulnar joint (DRUJ). In this biomechanical study, simulated peripheral tears of the TFCC were examined on the stability of the DRUJ. Restabilization effect of the DRUJ by ulnar shortening and direct repair of those injuries were sequentially examined. Method: The DRUJ stiffness was measured in intact, simulated two types of peripheral tears (ulnar and extended ulnodorsal) at three forearm positions: neutral, 60° pronation and 60° supination in 8 fresh frozen cadaver specimens. After the tears were sutured with stitches or after simulated ulnar shortening of 3 mm, the DRUJ stiffness was again measured. Results: The ulnar and ulnodorsal TFCC tears decreased the DRUJ stiffness significantly compared with the intact in all forearm positions. When ulnar shortening was done for the ulnar tear, the DRUJ stiffness increased significantly in the neutral and 60° pronated positions. When the ulnar TFCC tear was repaired, the DRUJ stiffness increased significantly in all forearm positions. DRUJ stiffness did not increase either with ulnar shortening or repair in ulnodorsal tear of the TFCC, however. Conclusion: The simulated TFCC tears indicated significant loss of DRUJ stiffness. Direct repair or ulnar shortening was effective only on treatment of the ulnar tear of the TFCC in this study.

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Two-Dimensional Terahertz Beam Steering Based on Trajectory Deflection of Leaky-Mode

Sato, K; Monnai, Y

IEEE TRANSACTIONS ON TERAHERTZ SCIENCE AND TECHNOLOGY 11 ( 6 ) 676 - 683 2021.11

ISSN 2156-342X

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Search for tens of MeV neutrinos associated with gamma-ray bursts in Super-Kamiokande

Abe, K; Bronner, C; Hayato, Y; Ikeda, M; Imaizumi, S; Ito, H; Kameda, J; Kataoka, Y; Kato, Y; Kishimoto, Y; Miura, M; Moriyama, S; Mochizuki, T; Nagao, Y; Nakahata, M; Nakajima, Y; Nakayama, S; Okada, T; Okamoto, K; Pronost, G; Sekiya, H; Shiozawa, M; Sonoda, Y; Suzuki, Y; Takeda, A; Takemoto, Y; Takenaka, A; Tanaka, H; Yano, T; Han, S; Kajita, T; Okumura, K; Tashiro, T; Wang, R; Xia, J; Megias, GD; Bravo-Berguño, D; Labarga, L; Marti, L; Zaldivar, B; Blaszczyk, FDM; Kearns, E; Raaf, JL; Stone, JL; Wan, L; Wester, T; Pointon, BW; Bian, J; Griskevich, NJ; Kropp, WR; Locke, S; Mine, S; Smy, MB; Sobel, HW; Takhistov, V; Weatherly, P; Ganezer, KS; Hill, J; Kim, JY; Lim, IT; Park, RG; Bodur, B; Scholberg, K; Walter, CW; Bernard, L; Coffani, A; Drapier, O; El Hedri, S; Giampaolo, A; Gonin, M; Mueller, TA; Paganini, P; Quilain, B; Ishizuka, T; Nakamura, T; Jang, JS; Learned, JG; Matsuno, S; Anthony, LHV; Litchfield, RP; Sztuc, AA; Uchida, Y; Berardi, V; Catanesi, MG; Radicioni, E; Calabria, NF; Machado, LN; De Rosa, G; Collazuol, G; Iacob, F; Lamoureux, M; Ospina, N; Ludovici, L; Nishimura, Y; Cao, S; Friend, M; Hasegawa, T; Ishida, T; Kobayashi, T; Jakkapu, M; Matsubara, T; Nakadaira, T; Nakamura, K; Oyama, Y; Sakashita, K; Sekiguchi, T; Tsukamoto, T; Boschi, T; Di Lodovico, F; Sedgwick, SM; Taani, M; Zsoldos, S; Hasegawa, M; Isobe, Y; Miyabe, H; Nakano, Y; Shiozawa, T; Sugimoto, T; Suzuki, AT; Takeuchi, Y; Yamamoto, S; Ali, A; Ashida, Y; Feng, J; Hirota, S; Jiang, M; Ichikawa, AK; Kikawa, T; Mori, M; Nakamura, KE; Nakaya, T; Wendell, RA; Yasutome, K; Fernandez, P; McCauley, N; Mehta, P; Pritchard, A; Tsui, KM; Fukuda, Y; Itow, Y; Menjo, H; Niwa, T; Sato, K; Tsukada, M; Mijakowski, P; Frankiewicz, K; Jung, CK; Vilela, C; Wilking, MJ; Yanagisawa, C; Fukuda, D; Harada, M; Hagiwara, K; Horai, T; Ishino, H; Ito, S; Koshio, Y; Ma, W; Piplani, N; Sakai, S; Sakuda, M; Takahira, Y; Xu, C; Kuno, Y; Barr, G; Barrow, D; Cook, L; Goldsack, A; Samani, S; Simpson, C; Wark, D; Nova, F; Yang, JY; Jenkins, SJ; Malek, M; McElwee, JM; Stone, O; Thiesse, MD; Thompson, LF; Okazawa, H; Choi, Y; Kim, SB; Yu, I; Nishijima, K; Koshiba, M; Iwamoto, K; Ogawa, N; Yokoyama, M; Martens, K; Vagins, MR; Izumiyama, S; Kuze, M; Tanaka, M; Yoshida, T; Inomoto, M; Ishitsuka, M; Matsumoto, R; Ohta, K; Shinoki, M; Martin, JF; Nantais, CM; Tanaka, HA; Towstego, T; Akutsu, R; Hartz, M; Konaka, A; de Perio, P; Prouse, NW; Chen, S; Xu, BD; Posiadala-Zezula, M; Richards, B; Jamieson, B; Walker, J; Minamino, A; Okamoto, K; Pintaudi, G; Sasaki, R

PROGRESS OF THEORETICAL AND EXPERIMENTAL PHYSICS 2021 ( 10 ) 2021.10

ISSN 2050-3911

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A Case of Coronal Intra-articular and Epiphyseal Fractures of the Metacarpal Head in Early Adolescence

Kato T., Iwamoto T., Suzuki T., Matsumura N., Nakamura M., Matsumoto M., Sato K.

Journal of Hand and Microsurgery (Journal of Hand and Microsurgery) 13 ( 4 ) 247 - 251 2021.10

ISSN 09743227

Intra-articular metacarpal head fracture is relatively rare. We report a case of coronal intra-articular and epiphyseal fractures of Salter-Harris type IV injury in the metacarpal head of the index finger. Surgery was performed by a dorsal approach. The volar fragment that was displaced proximally was gently reduced while bending the metacarpophalangeal (MP) joint, and it was fixed with cortical screws inserted proximal to the articular cartilage facilitating early rehabilitation. We consider the mechanism of injury to be a force applied from the distal phalanx that was transmitted unevenly to the volar side when the MP joint was slightly flexed. A three-dimensional computed tomography scan was useful in making the precise diagnosis, confirming the fracture pattern and planning fixation of the fracture.

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Preliminary Effect and Acceptability of an Intervention to Improve End-of-Life Care in Long-Term-Care Facilities: A Feasibility Study

Yamagata, C; Matsumoto, S; Miyashita, M; Kanno, Y; Taguchi, A; Sato, K; Fukahori, H

HEALTHCARE 9 ( 9 ) 2021.09

ISSN 2227-9032

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Search for Neutrinos in Coincidence with Gravitational Wave Events from the LIGO-Virgo O3a Observing Run with the Super-Kamiokande Detector

Abe, K; Bronner, C; Hayato, Y; Ikeda, M; Imaizumi, S; Kameda, J; Kanemura, Y; Kataoka, Y; Miki, S; Miura, M; Moriyama, S; Nagao, Y; Nakahata, M; Nakayama, S; Okada, T; Okamoto, K; Orii, A; Pronost, G; Sekiya, H; Shiozawa, M; Sonoda, Y; Suzuki, Y; Takeda, A; Takemoto, Y; Takenaka, A; Tanaka, H; Watanabe, S; Yano, T; Han, S; Kajita, T; Okumura, K; Tashiro, T; Wang, R; Xia, J; Megias, GD; Bravo-Berguño, D; Labarga, L; Marti, L; Zaldivar, B; Pointon, BW; Blaszczyk, FD; Kearns, E; Raaf, JL; Stone, JL; Wan, L; Wester, T; Bian, J; Griskevich, NJ; Kropp, WR; Locke, S; Mine, S; Smy, MB; Sobel, HW; Takhistov, V; Weatherly, P; Hill, J; Kim, JY; Lim, IT; Park, RG; Bodur, B; Scholberg, K; Walter, CW; Bernard, L; Coffani, A; Drapier, O; El Hedri, S; Giampaolo, A; Gonin, M; Mueller, TA; Paganini, P; Quilain, B; Ishizuka, T; Nakamura, T; Jang, JS; Learned, JG; Anthony, LHV; Martin, DGR; Sztuc, AA; Uchida, Y; Berardi, V; Catanesi, MG; Radicioni, E; Calabria, NF; Machado, LN; De Rosa, G; Collazuol, G; Iacob, F; Lamoureux, M; Ospina, N; Ludovici, L; Maekawa, Y; Nishimura, Y; Cao, S; Friend, M; Hasegawa, T; Ishida, T; Jakkapu, M; Kobayashi, T; Matsubara, T; Nakadaira, T; Nakamura, K; Oyama, Y; Sakashita, K; Sekiguchi, T; Tsukamoto, T; Kotsar, Y; Nakano, Y; Ozaki, H; Shiozawa, T; Suzuki, AT; Takeuchi, Y; Yamamoto, S; Ali, A; Ashida, Y; Feng, J; Hirota, S; Kikawa, T; Mori, M; Nakaya, T; Wendell, RA; Yasutome, K; Fernandez, P; McCauley, N; Mehta, P; Pritchard, A; Tsui, KM; Fukuda, Y; Itow, Y; Menjo, H; Niwa, T; Sato, K; Tsukada, M; Mijakowski, P; Jiang, J; Jung, CK; Vilela, C; Wilking, MJ; Yanagisawa, C; Hagiwara, K; Harada, M; Horai, T; Ishino, H; Ito, S; Koshio, Y; Kitagawa, H; Ma, W; Piplani, N; Sakai, S; Kuno, Y; Barr, G; Barrow, D; Cook, L; Goldsack, A; Samani, S; Simpson, C; Wark, D; Nova, F; Boschi, T; Di Lodovico, F; Migenda, J; Sedgwick, SM; Taani, M; Zsoldos, S; Yang, JY; Jenkins, SJ; Malek, M; McElwee, JM; Stone, O; Thiesse, MD; Thompson, LF; Okazawa, H; Kim, SB; Yu, I; Nishijima, K; Koshiba, M; Iwamoto, K; Nakajima, Y; Ogawa, N; Yokoyama, M; Martens, K; Vagins, MR; Izumiyama, S; Kuze, M; Tanaka, M; Yoshida, T; Inomoto, M; Ishitsuka, M; Ito, H; Matsumoto, R; Ohta, K; Shinoki, M; Martin, JF; Tanaka, HA; Towstego, T; Akutsu, R; Hartz, M; Konaka, A; de Perio, P; Prouse, NW; Chen, S; Xu, BD; Posiadala-Zezula, M; Hadley, D; Richards, B; Jamieson, B; Walker, J; Minamino, A; Okamoto, K; Pintaudi, G; Sano, S; Sasaki, R; Ichikawa, AK; Nakamura, K

ASTROPHYSICAL JOURNAL 918 ( 2 ) 2021.09

ISSN 0004-637X

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Risk factors for subsequent vertebral fracture after acute osteoporotic vertebral fractures

Inose, H; Kato, T; Ichimura, S; Nakamura, H; Hoshino, M; Togawa, D; Hirano, T; Tokuhashi, Y; Ohba, T; Haro, H; Tsuji, T; Sato, K; Sasao, Y; Takahata, M; Otani, K; Momoshima, S; Takahashi, K; Yuasa, M; Hirai, T; Yoshii, T; Okawa, A

EUROPEAN SPINE JOURNAL 30 ( 9 ) 2698 - 2707 2021.09

ISSN 0940-6719

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Restricted Wrist Rotation after an Ulnar Head Fracture: A Report of Two Cases

Kato, T; Abe, K; Sato, K; Nakamura, T

JOURNAL OF WRIST SURGERY 10 ( 04 ) 341 - 346 2021.08

ISSN 2163-3916

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Normal values and ranges of the lateral capitello-humeral angle in healthy children

Kiyota Y., Suzuki T., Inaba N., Nishiwaki M., Kimura H., Matsumura N., Sato K., Nakamura M., Matsumoto M., Iwamoto T.

Journal of Pediatric Orthopaedics Part B (Journal of Pediatric Orthopaedics Part B) 30 ( 4 ) 381 - 384 2021.07

ISSN 1060152X

The lateral capitello-humeral angle (LCHA), which is an index of sagittal alignment of the elbow, has gradually been adopted for the postoperative assessment of radiographic results. However, the normal values and ranges of the LCHA remain unclear. A retrospective cohort study was performed to evaluate the normal values and ranges of the LCHA in a sample of healthy children with even distributions of age, sex and laterality. A total of 168 radiographs of the elbows of healthy children (age range, 0–11 years) with even distributions of age, sex and laterality were reviewed. The primary aim was to analyze the normal values and ranges of the LCHA categorized by age, sex and laterality. The secondary aim was to assess the association of the LCHA with increasing age. The LCHA between sex or laterality in each age category was also compared. The mean LCHA of the 168 patients was 47.1º(range, 27º–63º). There was a weak association between the LCHA and increasing age (r = 0.41). The mean LCHA in females (49.1º) was significantly larger than that in males (45.1º). Significant sex-related differences were observed in age categories between 2 and 7 years. Results of this study will be useful in the postoperative radiographic assessment of sagittal alignment of the elbow in children.

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Evaluation of Dynamic Carpal Arch Stability following Carpal Tunnel Release Using Four-Dimensional Computed Tomography

Kimura H., Sato K., Matsumura N., Suzuki T., Iwamoto T., Ohori K., Yamada Y., Matsumoto M., Nakamura M., Jinzaki M., Nagura T.

Journal of Hand and Microsurgery (Journal of Hand and Microsurgery) 13 ( 3 ) 138 - 142 2021.07

ISSN 09743227

Introduction This study aimed to assess the carpal arch dynamics during active finger and wrist motion following carpal tunnel release using four-dimensional computed tomography (4D-CT). Materials and Methods Four patients who diagnosed with bilateral carpal tunnel syndrome and underwent unilateral carpal tunnel release were prospectively included. 4D-CT of the bilateral wrists during active finger and wrist motion was performed for 10 seconds at five frames per second. The distances between the tip of tuberosity of the scaphoid and the volar ridge of the pisiform (S-P distance) and volar ridge of trapezium and the tip of hook of hamate (T-H distance) were measured at each position and the values of S-P and T-H distances were compared between the postoperative and contralateral wrists. Results During finger motion, the S-P and T-H distances were not different at any position between the postoperative side and contralateral side. Conversely, S-P and T-H distances gradually increased in the postoperative wrists. The differences between the sides of S-P distance were significant, with >0 degrees of wrist extension, and differences of T-H distance were significant with >15 degrees of wrist extension. Conclusion This study demonstrated the carpal arch dynamics using 4D-CT and revealed that the carpal arch was widened with the wrist in extension after carpal tunnel release. This study suggests that the transverse carpal ligament plays an important role in maintaining carpal arch stability.

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Motion of the distal radioulnar joint in extension and flexion of the wrist using axial CT imaging of healthy volunteers

Suzuki T., Hayakawa K., Nakane T., Inaba N., Matsumura N., Sato K., Iwamoto T.

Journal of Orthopaedic Science (Journal of Orthopaedic Science) 26 ( 4 ) 610 - 615 2021.07

ISSN 09492658

Background: The midcarpal joint and the radiocarpal joint contribute to the extension and flexion of the wrist. Little is known about the contribution of the distal radioulnar joint (DRUJ) to the extension and flexion of the wrist. This study evaluated the ulnar motion in extension and flexion of the wrist using computed tomography (CT) imaging. Methods: A total of 30 wrists of healthy volunteers were enrolled. CT images of the axial sections of the DRUJ were obtained with 3 different positions of the wrist: 0° of extension (straight position), maximum active extension, and maximum active flexion. Each wrist motion was performed with 3 different forearm positions: neutral, pronation, and supination. Ulnar position at the DRUJ level was measured and ulnar position with the wrist in straight position was defined as baseline. The ulnar position was recorded as positive value when the position of the ulnar head was volar side and negative value when the position of the ulnar head was dorsal side. The difference from baseline in a position of maximum extension and flexion was evaluated. Results: In forearm neutral position and pronation, a value of ulnar position in maximum wrist flexion is significantly negative compared to that in the wrist straight position: the ulnar head moved dorsally from the wrist straight position to wrist flexion. In forearm supination, a value of ulnar position in maximum wrist extension is significantly positive compared to that in the wrist straight position: the ulnar head moved to the volar side from the wrist straight position to wrist extension. Conclusions: The ulnar head moves during extension and flexion of the wrist. The direction of the ulnar motion was different according to the wrist and forearm position.

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Exercise tolerance and quality of life in hemodynamically partially improved patients with chronic thromboembolic pulmonary hypertension treated with balloon pulmonary angioplasty

Miura K., Katsumata Y., Kawakami T., Ikura H., Ryuzaki T., Shiraishi Y., Fukui S., Kawakami M., Kohno T., Sato K., Fukuda K.

PLoS ONE (PLoS ONE) 16 ( July ) 2021.07

The efficacy of extensive balloon pulmonary angioplasty (BPA) beyond hemodynamic improvement in chronic thromboembolic pulmonary hypertension (CTEPH) patients has been verified. However, the relationship between extensive BPA in CTEPH patients after partial hemodynamic improvement and exercise tolerance or quality of life (QOL) remains unclear. We prospectively enrolled 22 CTEPH patients (66±10 years, females: 59%) when their mean pulmonary artery pressure initially decreased to <30 mmHg during BPA sessions. Hemodynamic and echocardiographic data, cardiopulmonary exercise testing, and QOL scores using the 36-item short form questionnaire (SF-36) were evaluated at enrollment (entry), just after the final BPA session (finish), and at the 6-month follow-up (followup). We analyzed whether extensive BPA improves exercise capacity and QOL scores over time. Moreover, the clinical characteristics leading to improvement were elucidated. The peak oxygen uptake (VO2) showed significant improvement at entry, finish, and follow-up (17.3±5.5, 18.4±5.9, and 18.9±5.3 mL/kg/min, respectively; P<0.001). Regarding the QOL, the physical component summary (PCS) scores significantly improved (32±11, 38±13, and 43±13, respectively; P<0.001), but the mental component summary scores remained unchanged. Linear regression analysis revealed that age and a low peak VO2 at entry were predictors of improvement in peak VO2, while low PCS scores and low TAPSE at entry were predictors of improvement in PCS scores. In conclusion, extensive BPA led to improved exercise tolerance and physical QOL scores, even in CTEPH patients with partially improved hemodynamics.

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Range of Motion after the Sauve-Kapandji and Darrach Procedures without Extensor Tendon Rupture

Kato, T; Suzuki, T; Kameyama, M; Okazaki, M; Morisawa, Y; Nishiwaki, M; Nakamura, T; Sato, K; Iwamoto, T

JOURNAL OF WRIST SURGERY 10 ( 03 ) 190 - 195 2021.06

ISSN 2163-3916

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