Papers - Matsumoto, Kazuaki

CYP2C19遺伝子多型と代謝物濃度をふまえたTDMによるボリコナゾール投与量適正化が有用であった2例.

茂見茜里, 松元一明, 渡辺英里香, 猪川和朗, 金澤直子, 横山雄太, 梅﨑雄太, 池田龍二, 森川則文, 武田泰生

日本外科感染症学会雑誌 13   661 - 667 2016.12

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1349-5755

Pregabalin prescription for terminally ill cancer patients receiving specialist palliative care in an acute hospital.

Ryo Yajima, Kazuaki Matsumoto, Yuya Ise, Norihito Suzuki, Yuta Yokoyama, Junko Kizu, Shiro Katayama.

JOURNAL OF PHARMACEUTICAL HEALTH CARE AND SCIENCES 2   29 2016.11

Research paper (scientific journal), Joint Work, Accepted,  ISSN  2055-0294

Pharmaceutical studies on and clinical application of olanzapine suppositories prepared as a hospital preparation.

Kazuaki Matsumoto, Satoru Kimura, Kenichi Takahashi, Yuta Yokoyama, Masayuki Miyazawa, Satoko Kushibiki, Morio Katamachi, Junko Kizu.

JOURNAL OF PHARMACEUTICAL HEALTH CARE AND SCIENCES 2   20 2016.09

Research paper (scientific journal), Joint Work, Accepted,  ISSN  2055-0294

The pharmacokinetics of ampicillin-sulbactam in anuric patients: dosing optimization for prophylaxis during cardiovascular surgery.

Yuta Yokoyama, Kazuaki Matsumoto, Kazuro Ikawa, Erika Watanabe, Hiroyuki Yamamoto, Yutaka Imoto, Norifumi Morikawa, Yasuo Takeda.

INTERNATIONAL JOURNAL OF CLINICAL PHARMACY 38   771 - 775 2016.08

Research paper (scientific journal), Joint Work, Accepted,  ISSN  2210-7711

医薬品副作用被害救済制度からみた抗菌薬が関連した副作用被害の実態.

佐藤沙紀, 松元一明, 黒田裕子, 木津純子.

日本化学療法学会雑誌 64   656 - 662 2016.07

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1340-7007

Therapeutic drug monitoring of voriconazole in Japanese patients: analysis based on clinical practice data.

Kazuaki Matsumoto, Kazuko Abematsu, Akari Shigemi, Naoko Kanazawa, Erika Watanabe, Yuta Yokoyama, Kazuro Ikawa, Norifumi Morikawa, Yasuo Takeda.

JOURNAL OF CHEMOTHERAPY 28   198 - 202 2016.06

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1120-009X

Pharmacokinetics and brain penetration of carbapenems in mice.

Kazuaki Matsumoto, Yuji Kurihara, Yuko Kuroda, Seiji Hori, Junko Kizu.

JOURNAL OF INFECTION AND CHEMOTHERAPY 22   346 - 349 2016.04

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1341-321X

Pharmacokinetic/pharmacodynamic analysis of teicoplanin in patients with MRSA infections.

Kazuaki Matsumoto, Erika Watanabe, Naoko Kanazawa, Tomohide Fukamizu, Akari Shigemi, Yuta Yokoyama, Kazuro Ikawa, Norifumi Morikawa, Yasuo Takeda.

CLINICAL PHARMACOLOGY: ADVANCES AND APPLICATIONS 8   15 - 18 2016.03

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1179-1438

自動車運転に影響を及ぼす医薬品の処方における薬局薬剤師の対応.

髙橋佑介, 松元一明, 黒田裕子, 大原整, 木津純子.

日本交通科学協議会誌 15 ( 3 ) 29 - 37 2016.03

Research paper (scientific journal), Joint Work, Accepted,  ISSN  13469282

A bundle that includes active surveillance, contact precaution for carriers, and cefazolin-based antimicrobial prophylaxis prevents methicillin-resistant Staphylococcus aureus infections in clean orthopedic surgery.

Hideki Kawamura, Kazuaki Matsumoto, Akari Shigemi, Michiyo Orita, Aya Nakagawa, Tomoko Nozima, Hiroyuki Tominaga, Setsuro Komiya, Koichi Tokuda, Junichiro Nishi.

AMERICAN JOURNAL OF INFECTION CONTROL (MOSBY-ELSEVIER)  44 ( 2 ) 210 - 214 2016.02

Research paper (scientific journal), Joint Work, Accepted,  ISSN  0196-6553

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Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a frequent cause of orthopedic surgical site infections (SSIs). The aim of this study was to evaluate the effect of a bundle approach in the prevention of orthopedic MRSA SSIs.
Material and Methods: MRSA active surveillance and decolonization were performed preoperatively at our institution from July 2004 until 2007. In January 2008, a bundle approach comprising contact precautions for MRSA-positive patients and cefazolin-based antimicrobial prophylaxis (AMP) stewardship was implemented. Data on the prevalence of MRSA SSIs, antimicrobial use density, duration of AMP, and the use of an alcohol antiseptic agent (L/1,000 patient-days) were evaluated during 2 periods: July 2004-December 2007 (period A) and January 2008-December 2012 (period B).
Results and Discussion: The MRSA SSI rate during period B (0.97%; 19 out of 1,966) was significantly lower than that during period A (2.17%; 29 out of 1,333; P =.003). The infection rate correlated negatively with both the cefazolin antimicrobial use density (r = -0.76; P = .0002) and the use of an alcohol antiseptic agent (r = -0.68; P = .002).
Conclusions: An infection-prevention bundle consisting of contact precautions for carriers and AMP stewardship in addition to active surveillance was associated with a significant decrease in the incidence of orthopedic MRSA SSIs. Copyright (c) 2016 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

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フレーバー添加レバミピド内用液剤の安定性に関する基礎検討.

矢島領, 今岡楓太, 輪湖哲也, 黒田裕子, 松元一明, 木津純子, 片山志郎.

YAKUGAKU ZASSHI 135   1397 - 1402 2015.12

Research paper (scientific journal), Joint Work, Accepted,  ISSN  0031-6903

Anti-inflammatory effects of linezolid on carrageenan-induced paw edema in rats.

Kazuaki Matsumoto, Shigeaki Obara, Yuko Kuroda, Junko Kizu.

JOURNAL OF INFECTION AND CHEMOTHERAPY (Elsevier)  21 ( 12 ) 889 - 891 2015.12

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1341-321X

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The immunomodulatory activity of linezolid has recently been reported using in vitro experimental models. However, the anti-inflammatory activity of linezolid has not yet been demonstrated using in vivo experimental models. Therefore, the aim of the present study was to demonstrate the anti-inflammatory activity of linezolid and other anti-MRSA agents using the carrageenan-induced rat paw edema model.The pretreatment with 50 mg/kg linezolid significantly suppressed edema rates, compared with control (5% glucose), with edema rates at 0.5 and 3 h after the administration of carrageenan being 17.3 ± 3.5 and 30.8 ± 3.0%, respectively. On the other hand, edema rates were not suppressed by the pretreatments with 50 mg/kg vancomycin, teicoplanin, arbekacin, and daptomycin. Furthermore, we demonstrated that linezolid exhibited anti-inflammatory activity in a concentration-dependent manner. These effects were observed at linezolid concentrations that are achievable in human serum with conventional dosing.In conclusion, the results of the present study suggest that the anti-inflammatory activities of linezolid, in addition to its antimicrobial effects, have a protective effect against destructive inflammatory responses in areas of inflammation.

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Pharmacokinetics of prophylactic ampicillin-sulbactam and dosing optimization in patients undergoing cardiovascular surgery with cardiopulmonary bypass.

Yuta Yokoyama, Kazuaki Matsumoto, Kazuro Ikawa, Erika Watanabe, HiroyukiYamamoto, Yutaka Imoto, Norifumi Morikawa, Yasuo Takeda.

BIOLOGICAL & PHARMACEUTICAL BULLETIN 38   1817 - 1821 2015.11

Research paper (scientific journal), Joint Work, Accepted,  ISSN  0918-6158

Trough level monitoring of intravenous busulfan to estimate the area under the plasma drug concentration-time curve in pediatric hematopoietic stem cell transplant recipients.

Erika Watanabe, Takuro Nishikawa, Kazuro Ikawa, Hiroki Yamaguchi, Takanari Abematsu, Shunsuke Nakagawa, Koichiro Kurauchi, Yuichi Kodama, Takayuki Tanabe, Yuichi Shinkoda, Kazuaki Matsumoto, Yasuhiro Okamoto, Yasuo Takeda, Yoshifumi Kawano.

INTERNATIONAL JOURNAL OF HEMATOLOGY 102   611 - 616 2015.11

Research paper (scientific journal), Joint Work, Accepted,  ISSN  0925-5710

溶出性・分割性からみた市販アセトアミノフェン坐剤の比較.

黒田裕子, 徳田真実, 井上舞鳥, 増田克哉, 寺島朝子, 前澤佳代子, 松元一明, 木津純子.

医療薬学 41   714 - 721 2015.10

Research paper (scientific journal), Joint Work, Accepted

Pharmacokinetics and dosing estimation of meropenem in Japanese patients receiving continuous venovenous hemodialysis.

Shinji Kawano, Kazuaki Matsumoto, Ryohei Hara, Yuko Kuroda, Kazuro Ikawa, Norifumi Morikawa, Tetsuya Horino, Seiji Hori, Junko Kizu.

JOURNAL OF INFECTION AND CHEMOTHERAPY 21   476 - 478 2015.06

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1341-321X

Pharmacokinetics and skin tissue penetration of daptomycin in rats.

Kazuaki Matsumoto, Masashi Kitaoka, Yuko Kuroda, Kazuro Ikawa, Norifumi Morikawa, Junichi Sasaki, Osamu Iketani, Satoshi Iwata, Tetsuya Horino, Seiji Hori, Junko Kizu.

CLINICAL PHARMACOLOGY: ADVANCES AND APPLICATIONS 7   79 - 82 2015.05

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1179-1438

医薬品副作用被害救済制度からみた一般用医薬品が関連した副作用被害の実態.

黒田裕子, 松元一明, 木津純子.

日本病院薬剤師会雑誌 51   425 - 428 2015.04

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1341-8815

Population pharmacokinetic-pharmacodynamic target attainment analysis of sulbactam in patients with impaired renal function: dosing considerations for Acinetobacter baumannii infections.

Yokoyama Yuta, Matsumoto Kazuaki, Ikawa Kazuro, Watanabe Erika, Morikawa Norifumi, Takeda Yasuo.

JOURNAL OF INFECTION AND CHEMOTHERAPY 21   284 - 289 2015.04

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1341-321X

Risk factors for ganciclovir-induced thrombocytopenia and leukopenia.

Matsumoto Kazuaki, Shigemi Akari, Ikawa Kazuro, Kanazawa Naoko, Fujisaki Yuko, Morikawa Norifumi, Takeda Yasuo.

BIOLOGICAL & PHARMACEUTICAL BULLETIN 38   235 - 238 2015.02

Research paper (scientific journal), Joint Work, Accepted,  ISSN  0918-6158