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Takahashi, Daisuke
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東京工業大学大学院, 理工学研究科, ２１世紀ＣＯＥプログラム：東京工業大学化学系６専攻 リサーチアシスタント
Japan Society for the Promotion of Science (JSPS) , Research Fellow (DC2)
Japan Society for the Promotion of Science (JSPS) , Research Fellow (PD)
Carlsberg Laboratory, Postdoctoral Fellow
Keio University, Research Associate (Non-tenured)（Department of Applied Chemistry, Faculty of Science and Technology）
Tokyo Institute of Technology, Faculty of Engineering, Applied chemistry
University, Graduated
Tokyo Institute of Technology, Graduate School of Science and Technology, Department of Applied Chemistry
Graduate School, Completed, Master's course
Tokyo Institute of Technology, Graduate School of Science and Technology, Department of Applied Chemistry
Graduate School, Completed, Doctoral course
Ph.D., Tokyo Institute of Technology, Coursework, 2006.03
鎖状鍵中間体を利用するデオキシオリゴ糖の合成と糖鎖マイクロアレイの開発研究
Nanotechnology/Materials / Synthetic organic chemistry (Carbohydrate Chemistry)
Nanotechnology/Materials / Chemical biology (Carbohydrate Chemistry)
Nanotechnology/Materials / Chemistry and chemical methodology of biomolecules (Synthetic Organic Chemistry)
Life Science / Bioorganic chemistry (Glycoscience)
Life Science / Pharmaceutical chemistry and drug development sciences (Structuer-Activity Relationship)
Carbohydrate Chemistry
Synthetic Organic Chemistry
Glycosylation Reaction
Chemical Biology
構造活性相関
天然糖脂質の系統的合成と新規化粧品素材の開発研究,
新規グリコシル化反応を用いた糖質医薬品の創製研究,
硫酸化糖質の系統的合成と生物活性,
位置及び立体選択的グリコシル化反応の開発,
Modern Natural Product Synthesis -Overcoming Difficulties
*DAISUKE TAKAHASHI, *Kazunobu Toshima, Springer Nature, 2024.05, Page： 20
Scope: Complex Oligosaccharides Synthesis—Challenges and Tactics, Contact page： 299-318 (Chapter 14) , Accepted
Advances in Carbohydrate Chemistry and Biochemistry
*DAISUKE TAKAHASHI, *Kazunobu Toshima, Elsevier, 2022.11, Page： 27
Scope: Boron-mediated aglycon delivery (BMAD) for the stereoselective synthesis of 1,2-cis glycosides, Contact page： 79-105 (Chapter 4) , Accepted
Comprehensive Glycoscience: Second Edition
*DAISUKE TAKAHASHI, *Kazunobu Toshima, Elsevier, 2021.06, Page： 48
Scope: 1,2-cis O-Glycosylation Methods, Contact page： 365-412 , Accepted
糖鎖の新機能開発・応用ハンドブック
高橋 大介、*戸嶋 一敦, エヌ・ティー・エス, 2015.08
Scope: 標的糖鎖光分解用生体機能分子, pp. 377-379.
糖鎖の新機能開発・応用ハンドブック
佐々木 要、高橋 大介、*戸嶋 一敦, エヌ・ティー・エス, 2015.08
Scope: 環境調和型グリコシル化反応, pp. 339-342.
Total Synthesis of Mono-Rhamnolipids Using Organophotoacid-Catalyzed Glycosylation and Their Antibacterial Activity
Kohei Higashiyama, Kanae Hosomi, Kazuki Senoo, Chigusa Hayashi, Masayuki Igarashi, *DAISUKE TAKAHASHI, *K. Toshima
CHEMICAL COMMUNICATIONS (Royal Society of Chemistry) 2025.12
Research paper (scientific journal), Joint Work, Corresponding author, Accepted
Synthesis and structure-activity relationship of azithromycin derivatives against non-tuberculous mycobacteria
Yuka Isozaki, Ali Ahsan Muzahid, Tatsuki Wakata, Maho Fujino, Yoshikazu Tanaka, Chigusa Hayashi, Yoshimasa Ishizaki, Tomokazu Ohishi, Ayumi Morita, Shunichi Ohba, Takeshi Yokoyama, *Masayuki Igarashi, *Kazunobu Toshima, *DAISUKE TAKAHASHI
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Elsevier) 304 118520 2025.12
Research paper (scientific journal), Joint Work, Last author, Corresponding author, Accepted
Glycosylation Using Diethyl Phosphite Donor Activated by Edible Polyphenol Ellagic Acid
Hidenari Shigeta, Ayato Watanabe, Chikako Shiraishi, DAISUKE TAKAHASHI, *Kazunobu Toshima
CARBOHYDRATE RESEARCH (Elsevier) 558 109712 (6 pages) 2025.10
Research paper (scientific journal), Joint Work, Accepted
Shuting Ji, Maniyamma Aswathy, Yuya Kuboki, Yoshio Takada, Kazunobu Toshima, DAISUKE TAKAHASHI, *Hiroko Ideo
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (MDPI) 26 ( 18 ) 9228 - 9228 2025.09
Research paper (scientific journal), Joint Work, Accepted
Yusha Li, Yuki Masuda, Yuzuha Miyazawa, DAISUKE TAKAHASHI, *Kazunobu Toshima
BIOORGANIC & MEDICINAL CHEMISTRY (Elsevier) 129 130371 - 130371 2025.08
Research paper (scientific journal), Joint Work, Accepted
Takahashi, Daisuke
科学研究費補助金研究成果報告書 2022
Challenges in the development of glycoconjugate vaccines against zoonosis based on organic chemistry
Takahashi, Daisuke
科学研究費補助金研究成果報告書 2021
Takahashi, Daisuke
学事振興資金研究成果実績報告書 (慶應義塾大学) 2020
Takahashi, Daisuke
学事振興資金研究成果実績報告書 (慶應義塾大学) 2019
Synthetic and structure-activity relationship studies on a natural glycolipid, terpioside B
Takahashi, Daisuke
学事振興資金研究成果実績報告書 (慶應義塾大学) 2018
Boron-mediated aglycon delivery for late-stage modifications: applications in chemical biology and pharmaceutical lead development
Yuka Isozaki, *Kazunobu Toshima, *DAISUKE TAKAHASHI
CHEMISTRY LETTERS (Chemical Society of Japan) 54 ( 5 ) upaf088 (9 pages) 2025.04
Joint Work, Last author, Corresponding author
高機能性化粧品素材の創製を指向したマンノシルエリスリトールリピッド（MEL）類縁体の合成と構造活性相関研究
孟 継坤, *戸嶋 一敦, *高橋 大介
オレオサイエンス 24 ( 11 ) 475 - 481 2024.11
Article, review, commentary, editorial, etc. (scientific journal), Joint Work, Last author, Corresponding author
ホウ素媒介アグリコン転移反応の新展開:反応開発,有用糖質合成,およびケミカルバイオロジーへの応用
*高橋 大介, *戸嶋 一敦
有機合成化学協会誌 82 ( 9 ) 856 - 866 2024.09
Article, review, commentary, editorial, etc. (scientific journal), Joint Work, Lead author, Corresponding author
Total Synthesis of Mannosylerythritol Lipids and Structure-Function Relationship Studies
*DAISUKE TAKAHASHI, Kazunobu Toshima
JOURNAL OF OLEO SCIENCE 73 ( 4 ) 539 - 546 2024.04
Article, review, commentary, editorial, etc. (scientific journal), Joint Work, Lead author, Corresponding author
Photo-Induced Glycosylations Using Organophotoacids: A New Environmentally Benign Carbohydrate Synthesis
*Kazunobu Toshima, DAISUKE TAKAHASHI, Yuka Isozaki
SYNLETT 35 777 - 788 2023.07
Article, review, commentary, editorial, etc. (scientific journal), Joint Work
Efficient Synthesis of Useful Carbohydrates and SAR Studies Toward the Creation of Pharmaceutical Leads
〇DAISUKE TAKAHASHI
[International presentation] Taiwan Glycoscience Alliance Lecture 2025 (Academia Sinica) (Institute of Biological Chemistry (IBC), Academia Sinica) ,
Public lecture, seminar, tutorial, course, or other speech
Synthesis of Useful Carbohydrates and SAR Studies Toward the Creation of Pharmaceutical Leads
〇DAISUKE TAKAHASHI
[International presentation] Taiwan Glycoscience Alliance Lecture 2025 (National Chung Hsing University) (National Chung Hsing University) ,
Public lecture, seminar, tutorial, course, or other speech
Synthesis of Biologically Active Carbohydrates and SAR Studies Toward the Creation of Pharmaceutical Leads
〇DAISUKE TAKAHASHI
[International presentation] Taiwan Glycoscience Alliance Lecture 2025 (National Tsing Hua University) (National Tsing Hua University) ,
Public lecture, seminar, tutorial, course, or other speech
Synthesis of Biologically Active Carbohydrates and Structure-Activity Relationship Studies Toward the Creation of Pharmaceutical Leads
〇DAISUKE TAKAHASHI
[International presentation] The 2025 Gordon Research Conference on Carbohydrates (Holderness School, New Hampshire, USA) ,
Oral presentation (invited, special)
Creation of Pharmaceutical Leads Based on Precise Carbohydrate Synthesis
〇DAISUKE TAKAHASHI
[International presentation] 7th Workshop on Radical and Electron Transfer Reactions (Central Park Hotel Songdo, Incheon, Republic of Korea) ,
Oral presentation (invited, special)
精密糖鎖合成を基盤とした次世代創薬モダリティーの創出
MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Transformative Research Areas (A), Principal investigator
⾰新的配糖化技術を基盤とした肺⾮結核性抗酸菌（NTM）症に対する新規 抗菌物質の創製
公益財団法人シオノギ感染症研究振興財団, 創薬研究助成金, Principal investigator
ホウ素媒介アグリコン転移を用いた1,2-cis フラノシドの精密化学合成と応用
MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Principal investigator
糖脂質型バイオサーファクタントの精密化学合成と構造機能相関による新規高機能性化粧品素材の創製
公益財団法人 コーセーコスメトロジー研究財団, 2022年度コスメトロジー研究助成, Principal investigator
広域スペクトルを有する抗ウイルス薬開発を目指した創薬標的探索と次世代創薬モダリティの基盤構築
AMED, AMED-CREST, Coinvestigator(s)
新規な抗生物質及びその製造方法
Date applied： 特願2023- 90620 2023.06
Patent, Joint
抗腫瘍剤
Date applied： 特願2014-140761 2014.07
Date announced： 特開2015-38061 2015.02
Date issued： 特許6403317 2018.10
Date registered： 2018.09
Patent, Joint
ノイラミニダーゼに対する酵素阻害剤
Date applied： 特願2010-022168 2010.02
Date announced： 特開2011-157325 2011.08
Patent, Joint
糖鎖アレイ及びその製造方法
Date applied： 特願2004-264922 2004.09
Date announced： 特開2006-78418 2006.03
Patent, Joint
Ｎ-グリコシルアミドの製造方法
Date applied： 特願2003-436790 2003.12
Date announced： 特開2005-187441 2005.07
Patent, Joint
2026年度 長瀬研究振興賞
2026.04, 公益財団法人 長瀬科学技術振興財団部
Type of Award： Award from publisher, newspaper, foundation, etc.
2023 Asian Core Program Lectureship Award
DAISUKE TAKAHASHI, 2023.12, The Organizing Committee of the 16th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-16), Efficient Synthesis of Biologically Active Glycosides by Boron-Mediated Aglycon Delivery and Their Applications in Chemical Biology
Type of Award： Award from international society, conference, symposium, etc.
Oleomaterial award
Daisuke Takahashi, 2022.08, Japan Oil Chemists' Society Oleomaterial Division, Efficient Total Synthesis of Mannosylerythritol Lipids and Their Structure-Function Studies
Type of Award： Award from Japanese society, conference, symposium, etc.
The Carbohydrate Research Award 2021
DAISUKE TAKAHASHI, 2021.04, The Editorial Board and Publisher of Carbohydrate Research
Type of Award： Award from publisher, newspaper, foundation, etc.
Incentive Award in Synthetic Organic Chemistry, Japan (2016)
2017.02, The Society of Synthetic Organic Chemistry, Japan, Precise Synthesis and Chemical Biological Studies of Certain Carbohydrates, and Creation of Artificial Bio-functional Molecules
Type of Award： Award from Japanese society, conference, symposium, etc.
GRADUATE RESEARCH ON CHEMISTRY, LIFE SCIENCE, AND INFORMATICS 2
2026
FUNDAMENTAL CHEMISTRY FOR BIOMOLECULES
2026
DOCTORAL RESEARCH ON CHEMISTRY, LIFE SCIENCE, AND INFORMATICS
2026
MOLECULAR LIFE CHEMISTRY 2
2026
LABORATORIES IN APPLIED CHEMISTRY D
2026
Molecular Life Chemistry 1
Keio University
Autumn Semester, Lecture, Within own ｆaculty, 1h
Molecular Life Chemistry 2
Keio University
Autumn Semester, Lecture, Within own ｆaculty, 1h
糖鎖、化学合成、生合成、酵素合成、糖鎖生物学、癌、インフルエンザ
生体物質化学基礎
Keio University
Autumn Semester, Lecture, Within own ｆaculty, 1h, 161people
LABORATORIES IN APPLIED CHEMISTRY D
Keio University
Autumn Semester, Laboratory work/practical work/exercise, Within own ｆaculty
SEMINAR IN APPLIED CHEMISTRY
Keio University
Full academic year
（プレスリリース）選択的な糖修飾法を用いて肺非結核性抗酸菌症の治療薬候補を開発－薬剤耐性菌に有効となる新規抗菌薬開発に期待－
慶應義塾大学・東北大学・微生物化学研究所, 2025.03
（プレスリリース）新型コロナウイルスの感染を抑制する糖質を開発－COVID-19の重症化を抑える治療薬開発に期待－
慶應義塾大学・大阪大学, 2024.10
（プレスリリース）糖質β-アラビノフラノシドを精密に合成する新手法の開発－配糖化を簡便に、抗アレルギー剤開発に期待－
慶應義塾大学, 2023.10
フコイダン、新型コロナに高阻害活性 慶大・阪大が確認
日刊工業新聞 (朝刊30面) , 2021.11
（プレスリリース）鳥類病原性大腸菌の抗原候補糖鎖を特定－化学合成を駆使したワクチン開発に期待－
慶應義塾大学, 2020.11
日本応用糖質科学会（会員）,
日本バイオサーファクタント勉強会（設立コアメンバー）,
Japan Oil Chemists' Society, member,
American Chemical Society, member,
FCCA (Forum: Carbohydrates Coming of Age) (member),
J-GlycoNet Collaborative Fellow, J-GlycoNet
Handling Editor, 日本糖質学会誌 Trends in Glycoscience and Glycotechnology
委員, 第33回IUPAC国際天然物化学会議組織委員会
日本学術振興会特別研究員等審査会専門委員, 独立行政法人 日本学術振興会
日本化学会 代表正会員, 日本化学会
Click to view the Scopus page. The data was downloaded from Scopus API in April 26, 2026, via http://api.elsevier.com and http://www.scopus.com .