論文 - 藤原　広和

【Multislice CT 2010 BOOK】 面検出器CTによる全脳CTDSA、perfusion CT　脳腫瘍への応用

藤原, 広和 and 百島, 祐貴

映像情報Medical 42 （ 7 ） 109 - 113 2010年06月

ISSN  1346-1354

Development of stiff shoulder in asymptomatic volunteers during ten-year follow-up in Japan.

Okada, Eijiro, Matsumoto, Morio, Ichihara, Daisuke, Chiba, Kazuhiro, Toyama, Yoshiaki, Fujiwara, Hirokazu, Momoshima, Suketaka, Nishiwaki, Yuji, Hashimoto, Takeshi, Watanabe, Masahiko, Inoue, Tomoo and Takahata, Takeshi

Journal of back and musculoskeletal rehabilitation 23   69 - 75 2010年

　概要を見る

The purpose of this study was to longitudinally evaluate relationships between the incidence of stiff shoulder and sagittal alignments of the cervical spine, age-related changes on magnetic resonance imaging (MRI) and life styles of the subjects.

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Gemcitabine and cisplatin chemotherapy induced reversible posterior leukoencephalopathy syndrome in a bladder cancer patient.

Maeda, Takahiro, Kikuchi, Eiji, Matsumoto, Kazuhiro, Yazawa, Satoshi, Hagiuda, Jun, Miyajima, Akira, Nakagawa, Ken, Fujiwara, Hirokazu, Hoshino, Haruhiko and Oya, Mototsugu

International journal of clinical oncology 15   508 - 11 2010年

　概要を見る

Reversible posterior leukoencephalopathy syndrome (RPLS) is a rare clinical entity, the common clinical symptoms of which are headache, disturbance of consciousness, altered mental status, seizures, and visual disturbance. Recently, some cases have been reported in association with the increased use of cytotoxic and immunosuppressive agents in cancer patients, and relevant reports have increased with advances in radiological examinations. We describe here the case of a 50-year-old man with advanced bladder cancer who suddenly experienced diminished spontaneity and speech, and finally became semicomatose. Two months previously, he had received gemcitabine and cisplatin chemotherapy. Computed tomography and magnetic resonance imaging revealed symmetrical edema of the posterior occipital lobe and thalamus. Based on these findings, we made a diagnosis of RPLS and treated him with supportive measures. His mental status gradually improved in 2 weeks, although slight neurological symptoms persisted. When the level of consciousness of a cancer patient worsens rapidly, this syndrome should be included in the differential diagnosis and recognized at an early stage. Early supportive management and discontinuation of the causative medication may reverse the clinical and radiological manifestations of the syndrome.

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Prospective ten-year follow-up study comparing patients with whiplash-associated disorders and asymptomatic subjects using magnetic resonance imaging.

Matsumoto, Morio, Okada, Eijiro, Ichihara, Daisuke, Chiba, Kazuhiro, Toyama, Yoshiaki, Fujiwara, Hirokazu, Momoshima, Suketaka, Nishiwaki, Yuji, Hashimoto, Takeshi, Inoue, Tomoo, Watanabe, Masahiko and Takahata, Takeshi

Spine 35   1684 - 90 2010年

　概要を見る

A prospective 10-year follow-up study of patients with whiplash-associated disorders (WAD) and asymptomatic volunteers.

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Age-related changes of thoracic and cervical intervertebral discs in asymptomatic subjects.

Matsumoto, Morio, Okada, Eijiro, Ichihara, Daisuke, Watanabe, Kota, Chiba, Kazuhiro, Toyama, Yoshiaki, Fujiwara, Hirokazu, Momoshima, Suketaka, Nishiwaki, Yuji, Hashimoto, Takeshi and Takahata, Takeshi

Spine 35   1359 - 64 2010年

　概要を見る

Magnetic resonance imaging (MRI) study on degeneration of the thoracic spine in asymptomatic subjects.

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Anterior cervical decompression and fusion accelerates adjacent segment degeneration: comparison with asymptomatic volunteers in a ten-year magnetic resonance imaging follow-up study.

Matsumoto, Morio, Okada, Eijiro, Ichihara, Daisuke, Watanabe, Kota, Chiba, Kazuhiro, Toyama, Yoshiaki, Fujiwara, Hirokazu, Momoshima, Suketaka, Nishiwaki, Yuji, Iwanami, Akio, Ikegami, Takeshi, Takahata, Takeshi and Hashimoto, Takeshi

Spine 35   36 - 43 2010年

　概要を見る

Prospective 10-year follow-up magnetic resonance imaging (MRI) study of patients who underwent anterior cervical decompression and fusion (ACDF) and healthy control subjects.

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【大脳白質をめぐって　画像と最新の知見】 大脳白質の変化・病変　放射線壊死

藤原, 広和 and 百島, 祐貴

Clinical Neuroscience 27 （ 11 ） 1240 - 1242 2009年11月

ISSN  0289-0585

【プライマリ・ケアに必要な画像診断のコツ】 頭部　複視・視覚障害の画像診断

藤原, 広和 and 百島, 祐貴

診断と治療 97 （ Suppl. ） 112 - 119 2009年04月

ISSN  0370-999X

Does the sagittal alignment of the cervical spine have an impact on disk degeneration? Minimum 10-year follow-up of asymptomatic volunteers.

Okada, Eijiro, Matsumoto, Morio, Ichihara, Daisuke, Chiba, Kazuhiro, Toyama, Yoshiaki, Fujiwara, Hirokazu, Momoshima, Suketaka, Nishiwaki, Yuji, Hashimoto, Takeshi, Ogawa, Jun, Watanabe, Masahiko and Takahata, Takeshi

European spine journal 18   1644 - 51 2009年

　概要を見る

There have been few studies that investigated and clarified the relationships between progression of degenerative changes and sagittal alignment of the cervical spine. The objective of the study was to longitudinally evaluate the relationships among progression of degenerative changes of the cervical spine with age, the development of clinical symptoms and sagittal alignment of the cervical spine in healthy subjects. Out of 497 symptom-free volunteers who underwent MRI and plain radiography of the cervical spine between 1994 and 1996, 113 subjects (45 males and 68 females) who responded to our contacts were enrolled. All subjects underwent another MRI at an average of 11.3 years after the initial study. Their mean age at the time of the initial imaging was 36.6 +/- 14.5 years (11-65 years). The items evaluated on MRI were (1) decrease in signal intensity of the intervertebral disks, (2) posterior disk protrusion, and (3) disk space narrowing. Each item was evaluated using a numerical grading system. The subjects were divided into four groups according to the age and sagittal alignment of the cervical spine, i.e., subjects under or over the age of 40 years, and subjects with the lordosis or non-lordosis type of sagittal alignment of the cervical spine. During the 10-year period, progression of decrease in signal intensity of the disk, posterior disk protrusion, and disk space narrowing were recognized in 64.6, 65.5, and 28.3% of the subjects, respectively. Progression of posterior disk protrusion was significantly more frequent in subjects over 40 years of age with non-lordosis type of sagittal alignment. Logistic regression analysis revealed that stiff shoulder was closely correlated with females (P = 0.001), and that numbness of the upper extremity was closely correlated with age (P = 0.030) and male (P = 0.038). However, no significant correlation between the sagittal alignment of the cervical spine and clinical symptoms was detected. Sagittal alignment of the cervical spine had some impact on the progression of degenerative changes of the cervical spine with aging; however, it had no correlation with the occurrence of future clinical symptoms.

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Longitudinal magnetic resonance imaging study on whiplash injury patients: minimum 10-year follow-up.

Ichihara, Daisuke, Okada, Eijiro, Chiba, Kazuhiro, Toyama, Yoshiaki, Fujiwara, Hirokazu, Momoshima, Suketaka, Nishiwaki, Yuji, Hashimoto, Takeshi, Ogawa, Jun, Watanabe, Masahiko, Takahata, Takeshi and Matsumoto, Morio

Journal of orthopaedic science 14   602 - 10 2009年

　概要を見る

We conducted a prospective long-term follow-up study to assess associations between magnetic resonance imaging (MRI) findings and changes in clinical symptoms, as well as factors relating to the prognosis of symptoms.

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Aging of the cervical spine in healthy volunteers: a 10-year longitudinal magnetic resonance imaging study.

Okada, Eijiro, Matsumoto, Morio, Ichihara, Daisuke, Chiba, Kazuhiro, Toyama, Yoshiaki, Fujiwara, Hirokazu, Momoshima, Suketaka, Nishiwaki, Yuji, Hashimoto, Takeshi, Ogawa, Jun, Watanabe, Masahiko and Takahata, Takeshi

Spine 34   706 - 12 2009年

　概要を見る

Prospective longitudinal study, mean follow-up period; 11.7 +/- 0.8 years was conducted from 1995 to 2007.

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【脳卒中の臨床　最新の実地治療・予防戦略】 脳卒中の臨床へのアプローチ　実地医家が知っておくべき基本的知識と臨床　脳卒中患者の画像診断(CT、MRI)のポイント

藤原, 広和 and 百島, 祐貴

Medical Practice 25 （ 12 ） 2126 - 2137 2008年12月

ISSN  0910-1551

脳血管障害 高血圧性脳症の画像診断

藤原, 広和 and 百島, 祐貴

Annual Review神経 2008   131 - 136 2008年01月

　概要を見る

高血圧性脳症は,悪性高血圧に伴い,頭痛,痙攣,意識障害等が引き起こされる病態として1928年にOppenheimerとFishbergにより初めて報告され,その画像所見が後頭部優位の可逆性の浮腫性変化であることは以前から知られていた.同様の臨床症状,画像所見が,妊娠子癇,免疫抑制剤の使用等でも認められ,Hanchyらはこれらの病態をまとめてreversible posterior leukoencephalopathy syndrome(RPLS)として報告した2).以来,同様の病態は多数報告され,posterior reversible encephalopathy syndrome(PRES)とも称せられる.高血圧性脳症とRPLS/PRESとは若干の異同もあるものの,病態生理,画像所見上は共通点が多く,本稿では古典的な高血圧性脳症のみならず,他の原因を含めたRPLS/PRES(以下PRES)の画像所見について概説する.(著者抄録)

【多系統萎縮症-update】 検査と診断　脳MRI

百島, 祐貴 and 藤原, 広和

Clinical Neuroscience 24 （ 9 ） 1012 - 1016 2006年09月

ISSN  0289-0585

Can selective CT angiography reduce the incidence of severe complications during transcatheter arterial embolization or infusion chemotherapy for thoracic diseases?

Tanaka, Osamu, Hashimoto, Subaru, Narimatsu, Yoshiaki, Fujiwara, Hirokazu, Kurata, Tadayoshi, Okuda, Shigeo, Yamagami, Takuji, Nishimura, Tsunehiko, Hiramatsu, Kyoichi and Kuribayashi, Sachio

Diagnostic and interventional radiology 12   201 - 5 2006年

　概要を見る

PURPOSE: To evaluate the usefulness of selective computed tomography (CT) angiography in preventing severe complications, such as spinal cord injury and broncho- esophageal fistula, during the transcatheter arterial embolization or infusion chemotherapy for thoracic diseases.

【医療環境の変化に対して放射線診療は今後どう対応すべきか　画像診断を中心に】　高度画像診断機器導入による画像診断へのインパクト　医療制度の変化を踏まえて　マルチスライスCTが放射線診療に与えるインパクト　心臓以外の領域

陣崎, 雅弘, 佐藤, 浩三, 藤原, 広和 and 栗林, 幸夫

日独医報 50 （ 3 ） 500 - 506 2005年09月

ISSN  0912-0351

【浸透圧性脱髄症候群　Pontine and extrapontine myelinolysis】　浸透圧性脱髄症候群の画像診断

百島, 祐貴 and 藤原, 広和

神経内科 63 （ 2 ） 128 - 131 2005年08月

ISSN  0386-9709

【Digital時代の脳神経画像診断】　Digital時代の画像診断　画像診断機器の進歩　CTとMRI

百島, 祐貴 and 藤原, 広和

Medicina 42 （ 3 ） 361 - 363 2005年03月

ISSN  0025-7699

PROPELLER diffusion-weighted magnetic resonance imaging of acute spinal epidural hematoma.

Fujiwara, H., Oki, K., Momoshima, S. and Kuribayashi, S.

Acta radiologica 46   539 - 42 2005年

ISSN  0284185051

　概要を見る

We present the case of an 86-year-old female with spontaneous spinal epidural hematoma. Although T1- and T2-weighted images showed the dilated posterior epidural space at the cervical spine, this finding was non-specific on conventional magnetic resonance imaging obtained 15 h after the onset of symptoms. Diffusion-weighted imaging with the use of periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER), which clearly revealed the high intensity hematoma, was useful for detection and diagnosis of acute spinal epidural hematoma.

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Leptomeningeal high signal intensity (ivy sign) on fluid-attenuated inversion-recovery (FLAIR) MR images in moyamoya disease.

Fujiwara, Hirokazu, Momoshima, Suketaka and Kuribayashi, Sachio

European journal of radiology 55   224 - 30 2005年

　概要を見る

There are a few reports on leptomeningeal high signal intensity (LMHI: ivy sign) on fluid-attenuated inversion-recovery (FLAIR) images in moyamoya disease, but the feature of this finding has not been completely understood. The purpose of this study was to characterize LMHI on FLAIR images in moyamoya disease and to assess usefulness of this finding in the diagnosis of moyamoya disease in conventional MR imaging.

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