論文 - 寺澤　悠理

Integration of cognitive and affective networks in humor comprehension

Shibata Midori, Terasawa Yuri, Umeda Satoshi

Neuropsychologia 65   137 - 145 2014年12月

ISSN  0028-3932

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<p>Humor comprehension is a complex process that requires the detection and resolution of the incongruity, eliciting a positive feeling of mirth or reward. We conducted a functional magnetic resonance imaging (fMRI) study to identify the key factors involved in this complex process. To reduce the influence of other factors, we utilized a group of sentences that were nearly identical across conditions (i.e., the first two sentences and the punch line were identical, but the third sentence was different). We found that the punch line (target sentence) in the funny condition induced a perception of funniness and elicited greater activation in language and semantic neural networks, which have been implicated in comprehension processing (i.e., incongruity detection and resolution). We also found increased activation in the mesolimbic reward regions, which have been implicated in the experience of positive rewards in the funny condition. Psycho-physiological interaction analyses revealed that language and semantic regions, such as inferior frontal gyrus (IFG), middle temporal gyrus (MTG), superior temporal gyrus (STG), superior frontal gyrus (SFG), and inferior parietal lobule (IPL) are simultaneously activated during humor comprehension processing. These analyses also revealed that the right MTG, the left IPL, and IFG showed enhanced connectivity with the midbrain. Our findings suggest that these networks play a central role in incongruity detection and resolution, as well as in positive emotional response.</p>

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Sleepiness induced by sleep-debt enhanced amygdala activity for subliminal signals of fear

Motomura Yuki, Kitamura Shingo, Oba Kentaro, Terasawa Yuri, Enomoto Minori, Katayose Yasuko, Hida Akiko, Moriguchi Yoshiya, Higuchi Shigekazu, Mishima Kazuo

BMC Neuroscience 15 （ 1 ）  2014年08月

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<p>Background: Emotional information is frequently processed below the level of consciousness, where subcortical regions of the brain are thought to play an important role. In the absence of conscious visual experience, patients with visual cortex damage discriminate the valence of emotional expression. Even in healthy individuals, a subliminal mechanism can be utilized to compensate for a functional decline in visual cognition of various causes such as strong sleepiness. In this study, sleep deprivation was simulated in healthy individuals to investigate functional alterations in the subliminal processing of emotional information caused by reduced conscious visual cognition and attention due to an increase in subjective sleepiness. Fourteen healthy adult men participated in a within-subject crossover study consisting of a 5-day session of sleep debt (SD, 4-h sleep) and a 5-day session of sleep control (SC, 8-h sleep). On the last day of each session, participants performed an emotional face-viewing task that included backward masking of nonconscious presentations during magnetic resonance scanning. Results: Finally, data from eleven participants who were unaware of nonconscious face presentations were analyzed. In fear contrasts, subjective sleepiness was significantly positively correlated with activity in the amygdala, ventromedial prefrontal cortex, hippocampus, and insular cortex, and was significantly negatively correlated with the secondary and tertiary visual areas and the fusiform face area. In fear-neutral contrasts, subjective sleepiness was significantly positively correlated with activity of the bilateral amygdala. Further, changes in subjective sleepiness (the difference between the SC and SD sessions) were correlated with both changes in amygdala activity and functional connectivity between the amygdala and superior colliculus in response to subliminal fearful faces.Conclusion: Sleepiness induced functional decline in the brain areas involved in conscious visual cognition of facial expressions, but also enhanced subliminal emotional processing via superior colliculus as represented by activity in the amygdala. These findings suggest that an evolutionally old and auxiliary subliminal hazard perception system is activated as a compensatory mechanism when conscious visual cognition is impaired. In addition, enhancement of subliminal emotional processing might cause involuntary emotional instability during sleep debt through changes in emotional response to or emotional evaluation of external stimuli.</p>

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Sleepiness induced by sleep-debt enhanced amygdala activity for subliminal signals of fear

Motomura, Yuki, Kitamura, Shingo, Oba, Kentaro, Terasawa, Yuri, Enomoto, Minori, Katayose, Yasuko, Hida, Akiko, Moriguchi, Yoshiya, Higuchi, Shigekazu, Mishima, Kazuo

BMC NEUROSCIENCE 15 2014年08月

研究論文（学術雑誌）, 共著,  ISSN  1471-2202

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Learning Process in Association with Interpersonal Conflict in Healthy Individuals, Using Fear Conditioning Paradigm

Tada, Mitsuhiro, Uchida, Hiroyuki, Maeda, Takaki, Konishi, Mika, Umeda, Satoshi, Terasawa, Yuri, Nakajima, Shinichiro, Mimura, Masaru, Takahashi, Takuya

BIOLOGICAL PSYCHIATRY 75 （ 9 ） 124S - 124S 2014年05月

研究論文（学術雑誌）,  ISSN  0006-3223

Interoceptive sensitivity predicts sensitivity to the emotions of others

Terasawa, Yuri, Moriguchi, Yoshiya, Tochizawa, Saiko, Umeda, Satoshi

COGNITION & EMOTION 28 （ 8 ） 1435 - 1448 2014年

研究論文（学術雑誌）, 共著,  ISSN  0269-9931

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Altered brain activity for phonological manipulation in dyslexic Japanese children

Kita Yosuke, Yamamoto Hisako, Oba Kentaro, Terasawa Yuri, Moriguchi Yoshiya, Uchiyama Hitoshi, Seki Ayumi, Koeda Tatsuya, Inagaki Masumi

Brain 136 （ 12 ） 3696 - 3708 2013年12月

ISSN  0006-8950

　概要を見る

<p>Because of unique linguistic characteristics, the prevalence rate of developmental dyslexia is relatively low in the Japanese language. Paradoxically, Japanese children have serious difficulty analysing phonological processes when they have dyslexia. Neurobiological deficits in Japanese dyslexia remain unclear and need to be identified, and may lead to better understanding of the commonality and diversity in the disorder among different linguistic systems. The present study investigated brain activity that underlies deficits in phonological awareness in Japanese dyslexic children using functional magnetic resonance imaging. We developed and conducted a phonological manipulation task to extract phonological processing skills and to minimize the influence of auditory working memory on healthy adults, typically developing children, and dyslexic children. Current experiments revealed that several brain regions participated in manipulating the phonological information including left inferior and middle frontal gyrus, left superior temporal gyrus, and bilateral basal ganglia. Moreover, dyslexic children showed altered activity in two brain regions. They showed hyperactivity in the basal ganglia compared with the two other groups, which reflects inefficient phonological processing. Hypoactivity in the left superior temporal gyrus was also found, suggesting difficulty in composing and processing phonological information. The altered brain activity shares similarity with those of dyslexic children in countries speaking alphabetical languages, but disparity also occurs between these two populations. These are initial findings concerning the neurobiological impairments in dyslexic Japanese children.</p>

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Altered brain activity for phonological manipulation in dyslexic Japanese children

Kita, Yosuke, Yamamoto, Hisako, Oba, Kentaro, Terasawa, Yuri, Moriguchi, Yoshiya, Uchiyama, Hitoshi, Seki, Ayumi, Koeda, Tatsuya, Inagaki, Masumi

BRAIN 136   3696 - 3708 2013年12月

研究論文（学術雑誌）, 査読有り,  ISSN  0006-8950

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AUTISTIC TRAITS AFFECT NEURAL CORRELATES OF VISUOSPATIAL PERSPECTIVE TAKING

Kanayama, Yusuke, Moriguchi, Yoshiya, Oba, Kentaro, Terasawa, Yuri, Murakami, Hiroki, Mishima, Kazuo, Kumano, Hiroaki

PSYCHOSOMATIC MEDICINE 75 （ 3 ） A165 - A165 2013年04月

研究論文（学術雑誌）,  ISSN  0033-3174

How does interoceptive awareness interact with the subjective experience of emotion? An fMRI Study

Terasawa, Yuri, Fukushima, Hirokata, Umeda, Satoshi

HUMAN BRAIN MAPPING 34 （ 3 ） 598 - 612 2013年03月

研究論文（学術雑誌）, 査読有り,  ISSN  1065-9471

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Anterior insular cortex mediates bodily sensibility and social anxiety

Terasawa, Yuri, Shibata, Midori, Moriguchi, Yoshiya, Umeda, Satoshi

SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE 8 （ 3 ） 259 - 266 2013年03月

研究論文（学術雑誌）, 査読有り,  ISSN  1749-5016

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Sleep Debt Elicits Negative Emotional Reaction through Diminished Amygdala-Anterior Cingulate Functional Connectivity

Motomura, Yuki, Kitamura, Shingo, Oba, Kentaro, Terasawa, Yuri, Enomoto, Minori, Katayose, Yasuko, Hida, Akiko, Moriguchi, Yoshiya, Higuchi, Shigekazu, Mishima, Kazuo

PLOS ONE 8 （ 2 ）  2013年02月

研究論文（学術雑誌）, 査読有り,  ISSN  1932-6203

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Deficits in prospective memory following damage to the prefrontal cortex

Umeda, Satoshi, Kurosaki, Yoshiko, Terasawa, Yuri, Kato, Motoichiro, Miyahara, Yasuyuki

NEUROPSYCHOLOGIA 49 （ 8 ） 2178 - 2184 2011年07月

研究論文（学術雑誌）, 査読有り,  ISSN  0028-3932

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Association between interoception and empathy

Fukushima Hirokata, Terasawa Yuri, Umeda Satoshi

International Journal of Psychophysiology 79 （ 2 ） 259 - 265 2011年02月

ISSN  0167-8760

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<p>Physiological bodily states play an important role in affective experiences. This study investigated whether the neural processing of internal body state (interoception) is associated with empathy, the understanding of the affective states of others. We used the 'heartbeat-evoked potential' (HEP), a surface electroencephalography (EEG) pattern, as a neural index of interoceptive processing. The HEP is contingent on the most prominent peak (R-wave) of the electrocardiogram (ECG) and is thought to reflect cortical processing of cardiac afferent input. Twenty-one healthy adults performed empathy and control tasks while EEG and ECG were recorded, where they made judgments based on either the affective or physical aspects of images of human eyes. HEP, ECG and heart rate in each task block were calculated and compared. Results showed that cardiac activity was not significantly different between tasks. In contrast, HEP showed a significant task difference, exhibited as an increased negativity during the empathy task over frontocentral sites at a latency of approximately 250-430. ms. Furthermore, a self-reported measure of empathy was associated with mean HEP amplitude during the period of task-related differentiation. These results suggest that afferent feedback from visceral activity may contribute to inferences about the affective state of others.</p>

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Association between interoception and empathy: Evidence from heartbeat-evoked brain potential

Fukushima, Hirokata, Terasawa, Yuri, Umeda, Satoshi

INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY 79 （ 2 ） 259 - 265 2011年02月

研究論文（学術雑誌）,  ISSN  0167-8760

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The reliability and validity of the Japanese version of the Levels of Emotional Awareness Scale (LEAS-J)

Igarashi Tetsuya, Komaki Gen, Lane Richard D., Moriguchi Yoshiya, Nishimura Hiroki, Arakawa Hiromi, Gondo Motoharu, Terasawa Yuri, Sullivan Corbet V., Maeda Motonari

BioPsychoSocial Medicine 5 2011年01月

　概要を見る

<p>Background: The Levels of Emotional Awareness Scale (LEAS) was developed to assess five levels of emotional awareness: bodily sensations, action tendencies, single emotions, blends of emotion, and combinations of blends. It is a paper and pencil performance questionnaire that presents 20 emotion-evoking scenes. We developed a Japanese version of the LEAS (LEAS-J), and its reliability and validity were examined.Methods: The LEAS-J level was independently assessed by two researchers who scored each response according to the LEAS scoring manual. High inter-rater reliability and internal consistency were obtained for the LEAS-J. Measures were socioeconomic status, LEAS-J, Toronto Alexithymia Scale-20 (TAS-20), Interpersonal Reactivity Index (IRI), and NEO Five-Factor Inventory (NEO-FFI). TAS-20, IRI and NEO-FFI were the measures used to explore the construct validity of LEAS-J, as it was predicted that higher scores on the LEAS-J would be related to fewer alexithymic features, greater empathetic ability, and a greater sense of cooperation with others. Questionnaires were completed by 344 university students.Results: The criterion-referenced validity was determined: a significant negative relationship was found with the externally-oriented thinking scores of TAS-20, and positive relationships were found with fantasy, perspective taking, and empathic concern on IRI and with extraversion, openness to experience, and agreeableness on NEO-FFI.Conclusions: Consistent with our expectations, the findings provide evidence that the LEAS-J has good reliability and validity. In addition, women had significantly higher scores than men on LEAS-J, showing that the gender difference identified in the original LEAS was cross-culturally consistent.</p>

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Autonomic reactivity of hypothesis-testing in decision-making

Terasawa Yuri, Umeda Satoshi

Psychologia 53 （ 3 ） 195 - 206 2010年09月

ISSN  0033-2852

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<p>Given the results of studies using the Iowa Gambling Task (IGT), emotion-based sensitivity to an anticipated outcome of one's own behavior has been suggested to be a significant factor in making advantageous decisions. Hypotheses-testing in performing IGT is essential for learning correct rules and elicits autonomic reactivity. In this study, participants were asked to concentrate on hypothesis-testing to learn undisclosed rules in the task which framework was similar to the IGT, rather than maximizing monetary reward. The amplitudes of skin conductance responses (SCRs) prior to card selection and following feedback were attenuated as participants came to accurately comprehend the task rules. The attenuation of SCRs resulted from reduced motivation to continue the hypotheses-testing. Our findings provide some evidence that observed autonomic responses partially reflect emotional reactions associated with the hypothesis-testing.</p>

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AUTONOMIC REACTIVITY OF HYPOTHESIS-TESTING IN DECISION-MAKING

Terasawa, Yuri, Umeda, Satoshi

PSYCHOLOGIA 53 （ 3 ） 195 - 206 2010年09月

研究論文（学術雑誌）, 査読有り,  ISSN  0033-2852

右島皮質損傷によってネガティブ表情の識別に混乱を示した一例

寺澤悠理・梅田 聡・斎藤文恵・加藤元一郎

高次脳機能研究 30 （ 2 ） 317 - 323 2010年01月

研究論文（学術雑誌）, 査読有り