論文 - 青山 和正
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Kaito S, Aoyama K, Oshima M, Tsuchiya A, Miyota M, Yamashita M, Koide S, Nakajima-Takagi Y, Kozuka-Hata H, Oyama M, Yabushita T, Ueno M, Hirao A, Tohyama K, Yamaguchi K, Furukawa Y, Kosako H, Yoshimi A, Goyama S, Nannya Y, Ogawa S, Agger K, Helin K, Koseki H, Nishiyama A, Nakanishi M, and Iwama A,
Nature Communications (Springer Science and Business Media LLC) 15 ( 1 ) 2024年08月
研究論文(学術雑誌), 共著, 査読有り
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The pathogenetic significance of exhausted T cells in a mouse model of mature B cell neoplasms
Shibamiya, A., Miyamoto-Nagai, Y., Koide, S., Oshima, M., Rizq, O., Aoyama, K., Nakajima-Takagi, Y., Kato, R., Kayamori, K., Isshiki, Y., Oshima-Hasegawa, N., Muto, T., Tsukamoto, S., Takeda, Y., Koyama-Nasu, R., Chiba, T., Honda, H., Yokote, K., Iwama, A., Sakaida, E. and Mimura, N.
Cancer Immunol Immunother 72 ( 8 ) 2635 - 2648 2023年08月
研究論文(学術雑誌), 査読有り, ISSN 0340-7004
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Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis
Nakajima-Takagi, Y., Oshima, M., Takano, J., Koide, S., Itokawa, N., Uemura, S., Yamashita, M., Andoh, S., Aoyama, K., Isshiki, Y., Shinoda, D., Saraya, A., Arai, F., Yamaguchi, K., Furukawa, Y., Koseki, H., Ikawa, T. and Iwama, A.
Elife 12 2023年06月
研究論文(学術雑誌), 査読有り, ISSN 2050-084x
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UTX inactivation in germinal center B cells promotes the development of multiple myeloma with extramedullary disease.
Ola Rizq, Naoya Mimura, Motohiko Oshima, Shuji Momose, Naoya Takayama, Naoki Itokawa, Shuhei Koide, Asuka Shibamiya, Yurie Miyamoto-Nagai, Mohamed Rizk, Yaeko Nakajima-Takagi, Kazumasa Aoyama, Changshan Wang, Atsunori Saraya, Masanori Seimiya, Mariko Watanabe, Satoshi Yamasaki, Tatsuhiro Shibata, Kiyoshi Yamaguchi, Yoichi Furukawa, Tetsuhiro Chiba, Emiko Sakaida, Chiaki Nakaseko, Jun-Ichi Tamaru, Yu-Tzu Tai, Kenneth C Anderson, Hiroaki Honda, Atsushi Iwama
Leukemia 2023年05月
研究論文(学術雑誌), 査読有り
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A culture platform to study quiescent hematopoietic stem cells following genome editing
Kohei Shiroshita, Hiroshi Kobayashi, Shintaro Watanuki, Daiki Karigane, Yuriko Sorimachi, Shinya Fujita, Shinpei Tamaki, Miho Haraguchi, Naoki Itokawa, Kazumasa Aoyama, Shuhei Koide, Yosuke Masamoto, Kenta Kobayashi, Ayako Nakamura-Ishizu, Mineo Kurokawa, Atsushi Iwama, Shinichiro Okamoto, Keisuke Kataoka, Keiyo Takubo
Cell Reports Methods 2022年12月
査読有り
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YAP1/TAZ activity maintains vascular integrity and organismal survival
Uemura, S., Yamashita, M., Aoyama, K., Yokomizo-Nakano, T., Oshima, M., Nishio, M., Masuko, M., Takizawa, J., Sone, H., Yamada, Y., Suzuki, A. and Iwama, A.
Biochem Biophys Res Commun 619 117 - 123 2022年09月
研究論文(学術雑誌), 査読有り, ISSN 0006-291x
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Epigenetic traits inscribed in chromatin accessibility in aged hematopoietic stem cells.
Naoki Itokawa, Motohiko Oshima, Shuhei Koide, Naoya Takayama, Wakako Kuribayashi, Yaeko Nakajima-Takagi, Kazumasa Aoyama, Satoshi Yamazaki, Kiyoshi Yamaguchi, Yoichi Furukawa, Koji Eto, Atsushi Iwama
Nature communications 13 ( 1 ) 2691 - 2691 2022年05月
研究論文(学術雑誌), 査読有り
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EZH1/2 inhibition augments the anti-tumor effects of sorafenib in hepatocellular carcinoma
Kusakabe, Y., Chiba, T., Oshima, M., Koide, S., Rizq, O., Aoyama, K., Ao, J., Kaneko, T., Kanzaki, H., Kanayama, K., Maeda, T., Saito, T., Nakagawa, R., Kobayashi, K., Kiyono, S., Nakamura, M., Ogasawara, S., Suzuki, E., Nakamoto, S., Yasui, S., Mikata, R., Muroyama, R., Kanda, T., Maruyama, H., Kato, J., Mimura, N., Ma, A., Jin, J., Zen, Y., Otsuka, M., Kaneda, A., Iwama, A. and Kato, N.
Sci Rep 11 ( 1 ) 21396 - 21396 2021年11月
研究論文(学術雑誌), 査読有り, ISSN 2045-2322
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Insufficiency of non-canonical PRC1 synergizes with JAK2V617F in the development of myelofibrosis.
Daisuke Shinoda, Yaeko Nakajima-Takagi, Motohiko Oshima, Shuhei Koide, Kazumasa Aoyama, Atsunori Saraya, Hironori Harada, Bahityar Rahmutulla, Atsushi Kaneda, Kiyoshi Yamaguchi, Yoichi Furukawa, Haruhiko Koseki, Kazuya Shimoda, Tomoaki Tanaka, Goro Sashida, Atsushi Iwama
Leukemia 36 ( 2 ) 452 - 463 2021年09月
研究論文(学術雑誌), 査読有り
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PRC2 insufficiency causes p53-dependent dyserythropoiesis in myelodysplastic syndrome.
Aoyama K, Shinoda D, Suzuki E, Nakajima-Takagi Y, Oshima M, Koide S, Rizq O, Si S, Tara S, Sashida G, Iwama A
Leukemia 35 ( 4 ) 1156 - 1165 2021年04月
研究論文(学術雑誌), 筆頭著者, 責任著者, 査読有り, ISSN 0887-6924
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Bmi1 counteracts hematopoietic stem cell aging by repressing target genes and enforcing the stem cell gene signature
Nitta, E., Itokawa, N., Yabata, S., Koide, S., Hou, L. B., Oshima, M., Aoyama, K., Saraya, A. and Iwama, A.
Biochem Biophys Res Commun 521 ( 3 ) 612 - 619 2020年01月
研究論文(学術雑誌), 査読有り, ISSN 0006-291x
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KDM2B in polycomb repressive complex 1.1 functions as a tumor suppressor in the initiation of T-cell leukemogenesis.
Yusuke Isshiki, Yaeko Nakajima-Takagi, Motohiko Oshima, Kazumasa Aoyama, Mohamed Rizk, Shuhei Kurosawa, Atsunori Saraya, Takashi Kondo, Emiko Sakaida, Chiaki Nakaseko, Koutaro Yokote, Haruhiko Koseki, Atsushi Iwama
Blood advances 3 ( 17 ) 2537 - 2549 2019年09月
研究論文(学術雑誌), 査読有り
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Bmi1 restricts the adipogenic differentiation of bone marrow stromal cells to maintain the integrity of the hematopoietic stem cell niche
Kato, Y., Hou, L. B., Miyagi, S., Nitta, E., Aoyama, K., Shinoda, D., Yamazaki, S., Kuribayashi, W., Isshiki, Y., Koide, S., Si, S., Saraya, A., Matsuzaki, Y., van Lohuizen, M. and Iwama, A.
Exp Hematol 76 24 - 37 2019年08月
研究論文(学術雑誌), 査読有り, ISSN 0301-472x
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Genetic and transcriptional landscape of plasma cells in POEMS syndrome
Nagao, Y., Mimura, N., Takeda, J., Yoshida, K., Shiozawa, Y., Oshima, M., Aoyama, K., Saraya, A., Koide, S., Rizq, O., Hasegawa, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Nishijima, D., Isshiki, Y., Kayamori, K., Kawajiri-Manako, C., Oshima-Hasegawa, N., Tsukamoto, S., Mitsukawa, S., Takeda, Y., Ohwada, C., Takeuchi, M., Iseki, T., Misawa, S., Miyano, S., Ohara, O., Yokote, K., Sakaida, E., Kuwabara, S., Sanada, M., Iwama, A., Ogawa, S. and Nakaseko, C.
Leukemia 33 ( 7 ) 1723 - 1735 2019年07月
研究論文(学術雑誌), 査読有り, ISSN 0887-6924
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Role for tyrosine phosphorylation of SUV39H1 histone methyltransferase in enhanced trimethylation of histone H3K9 via neuregulin-1/ErbB4 nuclear signaling.
Haruna Nakajo, Kenichi Ishibashi, Kazumasa Aoyama, Sho Kubota, Hitomi Hasegawa, Noritaka Yamaguchi, Naoto Yamaguchi
Biochemical and biophysical research communications 511 ( 4 ) 765 - 771 2019年04月
研究論文(学術雑誌), 査読有り
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PARP1 inhibition alleviates injury in ARH3-deficient mice and human cells
Mashimo, M., Bu, X., Aoyama, K., Kato, J., Ishiwata-Endo, H., Stevens, L. A., Kasamatsu, A., Wolfe, L. A., Toro, C., Adams, D., Markello, T., Gahl, W. A. and Moss, J.
JCI Insight 4 ( 4 ) 2019年02月
研究論文(学術雑誌), 筆頭著者, 査読有り, ISSN 2379-3708
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Forkhead box protein A1 confers resistance to transforming growth factor-β-induced apoptosis in breast cancer cells through inhibition of Smad3 nuclear translocation
Hirata, K., Takakura, Y., Shibazaki, M., Morii, M., Honda, T., Oshima, M., Aoyama, K., Iwama, A., Nakayama, Y., Takano, H., Yamaguchi, N. and Yamaguchi, N.
J Cell Biochem 120 ( 2 ) 2259 - 2270 2019年02月
研究論文(学術雑誌), 査読有り, ISSN 0730-2312
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Desuppression of TGF-β signaling via nuclear c-Abl-mediated phosphorylation of TIF1γ/TRIM33 at Tyr-524, -610, and -1048.
Yuki R, Tatewaki T, Yamaguchi N, Aoyama K, Honda T, Kubota S, Morii M, Manabe I, Kuga T, Tomonaga T, Yamaguchi N
Oncogene 38 ( 5 ) 637 - 655 2019年01月
研究論文(学術雑誌), 査読有り, ISSN 0950-9232
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Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome.
Tara S, Isshiki Y, Nakajima-Takagi Y, Oshima M, Aoyama K, Tanaka T, Shinoda D, Koide S, Saraya A, Miyagi S, Manabe I, Matsui H, Koseki H, Bardwell VJ, Iwama A
Blood 132 ( 23 ) 2470 - 2483 2018年12月
研究論文(学術雑誌), 査読有り, ISSN 0006-4971
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Ezh1 Targets Bivalent Genes to Maintain Self-Renewing Stem Cells in Ezh2-Insufficient Myelodysplastic Syndrome
Aoyama, K., Oshima, M., Koide, S., Suzuki, E., Mochizuki-Kashio, M., Kato, Y., Tara, S., Shinoda, D., Hiura, N., Nakajima-Takagi, Y., Sashida, G. and Iwama, A.
iScience 9 161 - 174 2018年10月
研究論文(学術雑誌), 筆頭著者, 責任著者, 査読有り, ISSN 2589-0042