Nishimura, Takehiro

写真a

Affiliation

Faculty of Pharmacy, Department of Pharmacy Division of Natural Medicines (Shiba-Kyoritsu)

Position

Research Associate/Assistant Professor/Instructor

Related Websites

Contact Address

1-5-30 Shibakoen, Minato-ku, Tokyo

External Links

Career 【 Display / hide

  • 2019.04
    -
    2022.03

    Next generation Natural Product Chemistry, Research & Development Dept., Senior Researcher

  • 2022.04
    -
    2022.06

    Keio Uninversity, Faculty of Pharmacy, 特任助教

  • 2022.07
    -
    Present

    Keio Uninversity, Faculty of Pharmacy, 助教

Academic Background 【 Display / hide

  • 2010.04
    -
    2014.03

    Tohoku University, 薬学部, 創薬科学科

    University, Graduated

  • 2014.04
    -
    2016.03

    Tohoku University, 薬学研究科

    Graduate School, Completed, Master's course

  • 2016.04
    -
    2019.03

    Tohoku University, 薬学研究科

    Graduate School, Completed, Doctoral course

Academic Degrees 【 Display / hide

  • 博士(薬科学), Tohoku University, Coursework, 2019.03

    中員環天然化合物の構造を基盤としたアルカロイド型化合物ライブラリーの構築

 

Research Areas 【 Display / hide

  • Life Science / Pharmaceutical chemistry and drug development sciences (Natural Product Chemistry, Medicinal Chemistry, Organic Chemistry)

 

Papers 【 Display / hide

  • A novel oxazole-containing tetraene compound, JBIR-159, produced by heterologous expression of the cryptic trans-AT type polyketide synthase biosynthetic gene cluster

    The Journal of Antibiotics 74 ( 5 ) 354 - 358 2021

    Research paper (scientific journal), Joint Work, Accepted

  • JBIR-155, a Specific Class D β-Lactamase Inhibitor of Microbial Origin

    Organic Letters 23 ( 11 ) 4415 - 4419 2021

    Research paper (scientific journal), Joint Work, Lead author, Accepted

  • Hemiacetal-less rapamycin derivatives designed and produced by genetic engineering of a type I polyketide synthase

    Scientific Reports 11 ( 1 ) 9944 2021

    Research paper (scientific journal), Joint Work, Accepted

  • In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives

    Nature Communications 11 ( 1 ) 4022 2020

    Research paper (scientific journal), Joint Work, Accepted

  • Removal of the E-Olefin Barrier of Humulene Leading to Unnatural Terpenoid-like Skeletons

    Organic Letters 20 ( 22 ) 7317 - 7320 2018

    Research paper (scientific journal), Joint Work, Lead author, Accepted

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Research Projects of Competitive Funds, etc. 【 Display / hide

  • 伸長型テルペノイド-ポリケチドハイブリッド型中分子化合物の創出

    2023.04
    -
    2026.03

    若手研究, Principal investigator

  • Construction of Mid-Size Molecule Library based on the Natural Product Re-Construction Strategy

    2022.08
    -
    2024.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 研究活動スタート支援, Principal investigator

 

Courses Taught 【 Display / hide

  • STUDY OF MAJOR FIELD: (NATURAL MEDICINES)

    2023

  • SEMINAR: (NATURAL MEDICINES)

    2023

  • RESEARCH FOR BACHELOR'S THESIS 1

    2023

  • PHARMACOGNOSY LABORATORY COURSE

    2023

  • PHARMACOGNOSY 2

    2023

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