KEIO RESEARCHERS INFORMATION SYSTEM

Career 【 Display / hide 】

Career 【 Display / hide 】

• 2019.04

  -

  2022.03

  Next generation Natural Product Chemistry, Research & Development Dept., Senior Researcher

• 2022.04

  -

  2022.06

  Keio Uninversity, Faculty of Pharmacy, 特任助教

• 2022.07

  -

  Present

  Keio Uninversity, Faculty of Pharmacy, 助教

Academic Background 【 Display / hide 】

Academic Background 【 Display / hide 】

• 2010.04

  -

  2014.03

  Tohoku University, 薬学部, 創薬科学科

  University, Graduated

• 2014.04

  -

  2016.03

  Tohoku University, 薬学研究科

  Graduate School, Completed, Master's course

• 2016.04

  -

  2019.03

  Tohoku University, 薬学研究科

  Graduate School, Completed, Doctoral course

Academic Degrees 【 Display / hide 】

Academic Degrees 【 Display / hide 】

• 博士(薬科学）, Tohoku University, Coursework, 2019.03

  中員環天然化合物の構造を基盤としたアルカロイド型化合物ライブラリーの構築

Research Areas 【 Display / hide 】

Research Areas 【 Display / hide 】

• Life Science / Pharmaceutical chemistry and drug development sciences (Natural Product Chemistry, Medicinal Chemistry, Organic Chemistry)

Papers 【 Display / hide 】

Papers 【 Display / hide 】

• A novel oxazole-containing tetraene compound, JBIR-159, produced by heterologous expression of the cryptic trans-AT type polyketide synthase biosynthetic gene cluster

  The Journal of Antibiotics 74 （ 5 ） 354 - 358 2021

  Research paper (scientific journal), Joint Work, Accepted

  • Access to Document (DOI)

• JBIR-155, a Specific Class D β-Lactamase Inhibitor of Microbial Origin

  Organic Letters 23 （ 11 ） 4415 - 4419 2021

  Research paper (scientific journal), Joint Work, Lead author, Accepted

  • Access to Document (DOI)

• Hemiacetal-less rapamycin derivatives designed and produced by genetic engineering of a type I polyketide synthase

  Scientific Reports 11 （ 1 ） 9944 2021

  Research paper (scientific journal), Joint Work, Accepted

  • Access to Document (DOI)

• In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives

  Nature Communications 11 （ 1 ） 4022 2020

  Research paper (scientific journal), Joint Work, Accepted

  • Access to Document (DOI)

• Removal of the E-Olefin Barrier of Humulene Leading to Unnatural Terpenoid-like Skeletons

  Organic Letters 20 （ 22 ） 7317 - 7320 2018

  Research paper (scientific journal), Joint Work, Lead author, Accepted

  • Access to Document (DOI)

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Research Projects of Competitive Funds, etc. 【 Display / hide 】

Research Projects of Competitive Funds, etc. 【 Display / hide 】

• Construction of Mid-Size Molecule Library based on the Natural Product Re-Construction Strategy

  2022.08

  -

  2024.03

  MEXT,JSPS, Grant-in-Aid for Scientific Research, 研究活動スタート支援, Principal investigator