Kanazawa, Hideko

写真a

Affiliation

Faculty of Pharmacy, Department of Pharmaceutical Sciences 創薬物理化学講座 (Shiba-Kyoritsu)

Position

Project Professor (Non-tenured)

Related Websites

External Links

 

Research Areas 【 Display / hide

  • Physical pharmacy

Research Keywords 【 Display / hide

  • Functional Polymer, HPLC, DDS

 

Books 【 Display / hide

  • 刺激応答性高分子ハンドブック

    長瀬 健一, 金澤 秀子, 株式会社エヌ・ティー・エス, 2018.12

    Scope: 温度応答性クロマトグラフィー

  • ゲルテクノロジーハンドブック、第1篇第3章第3節 機能性ナノ界面を用いた温度応答性クロマトグラフィー

    KANAZAWA Hideko, NTS, 2014.10

    Scope: 80-87

  • 製剤化のサイエンス

    KANAZAWA Hideko, 第6版ネオメディカル, 2014

  • わかりやすい薬剤学計算問題の解き方

    KANAZAWA Hideko, 改訂版ネオメディカル, 2014

  • 図解製剤学

    KANAZAWA Hideko, 南山堂, 2013.04

    Scope: 20-62

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Papers 【 Display / hide

  • Thermoresponsive Cationic Block Copolymer Brushes for Temperature-Modulated Stem Cell Separation

    Kenichi Nagase, Ayumu Ota, Tadashi Hirotani, Sota Yamada, Aya Mizutani Akimoto, Hideko Kanazawa

    Macromolecular Rapid Communications 2000308 2020.08

    Research paper (scientific journal), Joint Work, Accepted

  • Design of two complementary copolymers that work as a glue for cell-laden collagen gels

    Taihei Nishimoto, Ko Matsukawa, Kenichi Nagase, Hideko Kanazawa, Aya Mizutani Akimoto, Ryo Yoshida

    Chemical Communications 46 ( 10565 ) 10548 2020.08

    Research paper (scientific journal), Accepted

  • Antibody drug separation using thermoresponsive anionic polymer brush modified beads with optimised electrostatic and hydrophobic interactions

    Kenichi Nagase, Saki Ishii, Koji Ikeda, Sota Yamada, Daiju Ichikawa, Aya Akimoto, Yutaka Hattori, Hideko Kanazawa

    Scientific Reports 10, 11896, (2020) 10   11896 2020.07

    Research paper (scientific journal), Joint Work, Accepted

  • Simultaneous analysis of multiple oligonucleotides by temperature-responsive chromatography using a poly(N-isopropylacrylamide)-based stationary phase

    Yutaro Maekawa, Kaichi Yamazaki, Miwa Ihara, Kenichi Nagase, Hideko Kanazawa

    Analytical and Bioanalytical Chemistry 412   5341 - 5351 2020.06

    Research paper (scientific journal), Joint Work

  • Green analytical method for the simultaneous analysis of cytochrome P450 probe substrates by poly(N-isopropylacrylamide)-based temperature-responsive chromatography

    Yutaro Maekawa, Naoya Okamoto, Yuji Okada, Kenichi Nagase, Hideko Kanazawa

    Scientific Reports10(1), 8828, (2020) 10 ( 1 ) 8828 2020.06

    Research paper (scientific journal), Joint Work, Accepted

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Papers, etc., Registered in KOARA 【 Display / hide

Reviews, Commentaries, etc. 【 Display / hide

  • 細胞導入を制御可能な刺激応答性高分子を用いたナノキャリアの開発

    山之内 翔, 勝山 直哉, 蛭田 勇樹, 綾野 絵理, 金澤 秀子

    高分子論文集 75 ( 2 ) 116 - 127 2918.03

    Introduction and explanation (scientific journal), Joint Work

  • Temperature-responsive chromatography for bioseparations

    Kenichi Nagase, Hideko Kanazawa

    .Analytica Chimica Acta 1138   191 - 212 2020.11

    Introduction and explanation (scientific journal), Joint Work

  • 効果的な心筋細胞シート移植のためのVEGF徐放ファイバーマットの開発

    長瀬健一, 金澤秀子

    Drug Delivery System (じほう)  34 ( 3 ) 173 - 178 2019.07

    Introduction and explanation (scientific journal), Joint Work,  ISSN  0913-5006

  • 効果的ながん治療を目指したCD44ターゲティングナノキャリア

    山之内 翔, 金澤 秀子

    Drug Delivery System (じほう)  34 ( 1 ) 38 - 45 2019.01

    Introduction and explanation (scientific journal), Joint Work,  ISSN  09135006

  • Comparison of plasma propofol concentration for apnea, response to mechanical ventilation, and airway device between endotracheal tube and supraglottic airway device in beagles

    Iizuka T., Masui K., Kanazawa H., Nishimura R.

    Journal of Veterinary Medical Science (Journal of Veterinary Medical Science)  80 ( 9 ) 1420 - 1423 2018.09

    ISSN  09167250

     View Summary

    © 2018 The Japanese Society of Veterinary Science. The relationships between propofol plasma concentrations and the pharmacodynamic endpoints may differ according to a type of airway device. To clarify these relationships in different airway devices would be useful to avoid the complication such as apnea and intraoperative awareness. The aim of this study was to investigate the influence of difference of airway device on propofol requirement during maintenance of anesthesia in dogs. We compared the influence of airway devices on the plasma propofol concentrations for apnea, response to mechanical ventilation, and response to airway device between endotracheal tube (ETT) and supraglottic airway device (SGAD) in Beagles. The pharmacodynamic effects were repeatedly assessed at varying propofol concentrations. The plasma concentrations (mean ± SD) of propofol in the ETT and SGAD groups were 10.2 ± 1.8 and 10.9 ± 2.4 µg/ml for apnea (P=0.438), 7.9 ± 1.2 and 7.4 ± 1.5 µg/ml for response to mechanical ventilation (P=0.268), and 5.2 ± 0.7 and 5.4 ± 1.5 µg/ml for response to airway device (P=0.580), respectively. Required propofol concentration during maintenance of anesthesia may be similar between ETT and SGAD. Without moderate to strong stimuli such as airway device insertion or painful stimulation during surgery, the type of airway device may have little impact on required propofol concentration during maintenance of anesthesia in dogs.

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Presentations 【 Display / hide

  • 温度応答性培養基材を用いたラベルフリー肝細胞分離法の開発

    小島直人,長瀬健一,赤池敏宏,後藤光昭,金澤秀子

    第64回 日本薬学会 関東支部, 2020.09, Poster (general)

  • 機能性高分子を用いた温度制御型タンパク質分離法の開発

    北澤 早紀子, 山田 創太, 長瀬 健一, 金澤 秀子

    日本分析化学会 第69年会, 2020.09, Poster (general)

  • 正電荷を有する温度応答性充填剤を用いたラベルフリー細胞分離法の開発

    枝常 吾郎, 山田 創太, 長瀬 健一, 金澤 秀子

    日本分析化学会 第69年会, 2020.09, Poster (general)

  • オリゴヌクレオチド分離のための温度応答性アニオン交換クロマトグラフィーの開発

    山崎 開智, 前川 祐太朗, 井原 美和, 長瀬 健一, 金澤 秀子

    日本分析化学会 第69年会, 2020.09, Poster (general)

  • 温度応答性-カチオン性高分子ブラシとタンパク質・細胞との相互作用制御

    長瀬健一,金澤 秀子

    第69回高分子討論会, 2020.09, Oral Presentation(general)

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Research Projects of Competitive Funds, etc. 【 Display / hide

  • 再生医療を革新的に効率化する機能性バイオ界面の創製

    2019.04
    -
    2023.03

    文部科学省・日本学術振興会, 科学研究費助成事業, 長瀬健一, 基盤研究(B), Co-investigator

  • 酸素産生ナノ粒子を用いた革新的細胞組織移植法の確立

    2018.04
    -
    2021.03

    文部科学省・日本学術振興会, 科学研究費助成事業, 長瀬健一, 挑戦的研究(萌芽), Co-investigator

  • Development of high performance separation and purification technology for cell therapy and biopharmaceuticals

    2016.04
    -
    2019.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 金澤 秀子, Grant-in-Aid for Scientific Research (B), Principal Investigator

  • 疾患バイオマーカー探索のための機能的RNA-タンパク複合体分離精製法の構築

    2013.04
    -
    2015.03

    文部科学省・日本学術振興会, 科学研究費助成事業, 金澤秀子, 基盤研究(B), Principal Investigator

  • 生体内動態の時空間制御による機能的核酸デリバリーシステムの創製

    2013.04
    -
    2014.03

    文部科学省・日本学術振興会, 科学研究費助成事業, 金澤秀子, 挑戦的萌芽研究, Principal Investigator

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Awards 【 Display / hide

  • 日本分析化学会 学会賞

    金澤 秀子, 2017.09, 日本分析化学会, 温度応答性クロマトグラフィーを用いた分離・分析システムの創製とその応用

    Type of Award: Awards of National Conference, Council and Symposium.  Country: 日本

  • クロマトグラフィー科学会学会賞

    金澤秀子., 2008.12, クロマトグラフィー科学会, 機能性高分子を用いた温度制御型新規分離システムの開発.

  • HPLC 2005 Best Poster Paper Award First Prize.

    Hideko Kanazawa, 2005.07, 29th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2005)

    Type of Award: International Academic Awards

  • 日本分析化学会関東支部新世紀賞

    金澤秀子., 2002.03, 日本分析化学会関東支部

    Type of Award: Awards of National Conference, Council and Symposium

  • 生命科学啓明賞

    金澤秀子., 2002.03, 財団法人 啓明会

    Type of Award: Awards of Publisher, Newspaper Company and Foundation

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Courses Taught 【 Display / hide

  • DOCTORAL LECTURE ON CHEMICAL PHARMACY 1

    2021

  • ADVANCED DRUG DELIVERY AND PHARMACOKINETICS

    2021

  • STUDY OF MAJOR FIELD: (PHARMACEUTICAL PHYSICAL CHEMISTRY)

    2020

  • SEMINAR: (PHARMACEUTICAL PHYSICAL CHEMISTRY)

    2020

  • RESEARCH FOR BACHELOR'S THESIS 1

    2020

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