Kasahara, Tadashi

写真a

Affiliation

Faculty of Pharmacy (Mita)

Position

Professor Emeritus

Profile Summary 【 Display / hide

  • '''''''Role of inflammatory cytokine and chemokine in the regulation of immunity, inflammation and allergic responses. Drugs and agents regulating inflammatory responses are being scrutinized vigorously.'''''''

Career 【 Display / hide

  • 1974.04
    -
    1983.09

    自治医科大学医学部・助手

  • 1983.10
    -
    1986.03

    自治医科大学医学部・講師

  • 1983.10
    -
    1995.03

    自治医科大学医学部・助教授

  • 1995.04
    -
    2008.03

    共立薬科大学・教授

  • 2005.07
    -
    2008.03

    共立薬科大学・常務理事(教育担当)

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Academic Background 【 Display / hide

  • 1972.03

    The University of Tokyo, Faculty of Pharmaceutical Science

    University, Graduated

  • 1974.03

    The University of Tokyo, Graduate School, Division of Pharmaceutical Sciences

    Graduate School, Completed, Master's course

Academic Degrees 【 Display / hide

  • 薬学博士, The University of Tokyo, Dissertation, 1978.02

 

Research Areas 【 Display / hide

  • Life Science / Pharmaceutical hygiene and biochemistry (Biological System Pharmaceutical Science)

Research Keywords 【 Display / hide

  • Immunology

  • Biochemistry

Research Themes 【 Display / hide

  • (1) Role of focal adhesion kinase in the anti-apoptotic signaling and the regulatory role in the metastasis of melanoma cells in vivo. (2) Role of JAK2 mutation in the tumorigenesis and the quest of, 

    2006
    -
    2011

     View Summary

    (1) Role of focal adhesion kinase in the anti-apoptotic signaling and the regulatory role in the metastasis of melanoma cells in vivo. (2) Role of JAK2 mutation in the tumorigenesis and the quest of effective anti-tumorigenic drugs inhibiting JAK2 signaling pathway.

 

Books 【 Display / hide

  • ヒューマニズム薬学入門

    KASAHARA Tadashi, 培風館, 2012.03

    Scope: 1-185

  • スタンダード薬学シリーズ、生物系薬学III.

    笠原 忠., 東京/東京化学同人, 2006.03

    Scope: 77-81

  • スタンダード薬学シリーズ、生物系薬学II.

    日本薬学会編., 東京/東京化学同人, 2005.06

    Scope: 302-315

  • スタンダード免疫学(第2版).

    小林芳郎,笠原 忠,片桐拓也,渡辺直子., 東京/丸善, 2003.08

    Scope: 129-205

  • 臨床免疫39(4) サイトカインー過去,現在,未来.

    Joost J Oppenheim, 笠原 忠(訳)., 東京/科学評論社, 2003.04

    Scope: 434-442

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Papers 【 Display / hide

  • Temporal expression and mitochondrial localization of a Foxp2 isoform lacking the forkhead domain in developing Purkinje cells.

    KASAHARA Tadashi

    J Neurochem. 0 ( 0 ) 0 2011.11

    Research paper (scientific journal), Single Work

  • Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin.

    KASAHARA Tadashi

    Int Immunopharmacol 11 ( 9 ) 1150-1159 2011.09

    Research paper (scientific journal), Single Work

  • Aurora kinase A critically contributes to the resistance to anti-cancer drug cisplatin in JAK2 V617F mutant-induced transformed cells.

    KASAHARA Tadashi

    FEBS letters 585 ( 12 ) 1884-1890 2011.06

    Research paper (scientific journal), Single Work, Accepted

  • Akt activation through the phosphorylation of erythropoietin receptor at tyrosine 479 is required for myeloproliferative disorder-associated JAK2 V617F mutant-induced cellular transformation.

    Kamishimoto J, Tago K, Kasahara T, Funakoshi-Tago M.

    Cell Signaling 23 ( 5 ) 849-856 2011.05

    Research paper (scientific journal), Single Work, Accepted

  • JAK2 is an important signal transducer in IL-33-induced NF-κB activation.

    Funakoshi-Tago M, Tago K, Sato Y, Tominaga S, Kasahara T.

    Cell Signaling 23 ( 2 ) 363-370 2011.02

    Research paper (scientific journal), Single Work, Accepted

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Papers, etc., Registered in KOARA 【 Display / hide

Presentations 【 Display / hide

  • 薬剤師教育における1・2年次体験学習の効果.

    ○小林典子, 木津純子, 笠原忠.

    第18回日本医療薬学会年会 (札幌) , 

    2008.09

    Poster presentation

  • 実務実習事前学習充実に向けた学生による実習評価.

    ○小林典子,木津純子,笠原忠.

    医療薬学フォーラム2008 (東京) , 

    2008.07

    Poster presentation

  • TNFシグナル系におけるTNF Receptor Associated Factor 6の役割.

    ○鎌田智之,橋口雄輔,市川大樹,多胡めぐみ,横田恵理子,園田よし子,井上純一郎,笠原忠.

    日本薬学会第128年会 (横浜市) , 

    2008.03

    Poster presentation

  • 破骨細胞における中間径フィラメントの役割について.

    安達玲子、櫻井智子、笠原忠、鈴木和博、手島玲子.

    日本薬学会第128年会 (横浜市) , 

    2008.03

    Poster presentation

  • 無脊椎動物由来糖脂質の合成研究(33)フトミミズ由来糖脂質の合成とその応用.

    ○信太幸彦, 島村寛, 根岸夏子, 羽田紀康, 園田よし子, 笠原忠, 竹田忠紘.

    日本薬学会第128年会 (横浜) , 

    2008.03

    Poster presentation

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