Papers - YAMAURA Katsunori

心不全患者のトリプルワーミー回避に関する歯薬連携の新規モデル構築の契機となった1例

前瀬鞠, 近藤慎吾, 林直子, 岩田紘樹, 小林典子, 岡本侑子, 榎木裕紀, 漆畑俊哉, 山浦克典

薬局薬学 (日本コミュニティファーマシー協会)   2026

Last author, Accepted

Loneliness and analgesic overuse among low-dose estrogen-progestin users in Japan

Takuma Fujimoto, Hiroki Iwata, Noriko Kobayashi, Shingo Kondo, Katsunori Yamaura

BMC Women’s Health (BMC)  25 ( 422 )  2025.09

Research paper (scientific journal), Single Work, Last author, Corresponding author, Accepted

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Purpose Loneliness is related to menstrual disorders and medication use. Loneliness and pain are related and may
be associated with analgesic use. The aim of this study was to investigate the prevalence of concomitant analgesic
use and overuse, and to clarify factors associated with loneliness and analgesic overuse among women who are low
dose estrogen-progestin (LEP) users.
Methods Women in their 20s and 30s were randomly selected from a research company’s web panel (Macromill,
Inc.) and LEP users were screened. The survey included analgesic concomitant use days per month and the Three
Item Loneliness Scale (TIL). Logistic regression analysis was performed with high TIL score (≥ 6) and analgesic use ≥ 10
days per month as the objective variables.
Results A total of 516 valid responses from LEP users were analyzed. Among them, 64.1% reported concomitant
analgesic use on ≥ 1 day per month, 11.2% on ≥ 10 days per month, and 45.7% had high TIL score. High TIL score was
significantly associated with concomitant analgesic use on ≥ 1 day per month (odds ratio [OR] 1.76, 95% confidence
interval [95%CI] 1.18–2.63, p = 0.006). Concomitant analgesic use on ≥ 10 days per month was significantly associated
with endometriosis (OR 5.25, 95%CI 2.15–12.81, p < 0.001) and concomitant analgesic use for low back pain (OR 4.67,
95%CI 1.65–13.18, p = 0.04).
Conclusions To our knowledge, this is the first detailed study to investigate concomitant analgesic use and overuse
among LEP users. Loneliness was found to be prevalent in this population and was associated with concomitant
analgesic use, potentially reflecting underlying patterns of frequent or habitual analgesic intake. Furthermore,
concomitant analgesic overuse was linked to conditions such as endometriosis and low back pain, underscoring the
importance of medication monitoring that takes into account both loneliness and the self-recording of menstrual
symptoms. Greater attention by healthcare professionals to the psychosocial context of concomitant analgesic
overuse and loneliness may facilitate more meaningful patient dialogue and contribute to improved quality of life.

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A Simulated Interprofessional Team Conference Using Cross-Training for Junior Healthcare Students in Interprofessional Education: a Qualitative Content Analysis

Etsuko Tomisaki, Junji Haruta, Takashi Horiguchi, Tomoko Arahata, Rika Fukui, Shunsuke Uno, Takayuki Ando, Tetsuhiro Yoshino, Satoko Ishikawa, Sayo Suzuki, Katsunori Yamaura, Toshiaki Monkawa

Advances in Medical Education and Practice (Dovepress)  16   583 - 594 2025.04

Research paper (scientific journal), Joint Work, Accepted

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Purpose: In 2021, we introduced a new simulation-based learning program focusing on a roleplay conference before patient discharge.
This study aimed to evaluate the program’s effectiveness and highlight the significance of cross-training in interprofessional education (IPE).
Methods: In September 2023, the program included 346 students (98 medical, 110 nursing, and 138 pharmacy students). The
students’ reflective writing was analyzed using inductive content analysis to describe their learning and perspectives. The original
items, subcategories, and main categories were extracted. The simulation involved the students role-playing various healthcare
professionals during a discharge-planning conference for a stroke patient. This allowed them to experience the challenges and
dynamics of interprofessional collaboration.
Results: Student feedback emphasized the importance of understanding what constitutes a good healthcare team. A total of 203 items
were grouped into eight main categories and 17 subcategories, including patient-centered care (related to the importance of patient-
centered care, supporting patient decision-making, communicating with patients during conferences, and facilitating decision-making
processes), contrasts in patient and interprofessional communication, conference communication (challenge of building consensus, the
way to proceed conferences, importance of conference preparation, and process of information aggregation and realization of
outcomes), mutual recognition and role contribution, building relationships (importance of daily interprofessional communication),
understanding one’s profession (reflection on one’s own profession, understanding the roles of different professions, and communica
tion within one’s own professional context), recursion into learning (motivation for continuous learning and improvement), and
understanding other professions (understanding the role and perspectives of other professions and recognizing professional differ
ences). Specific feedback highlighted improved empathy and communication skills. Students recognized the value of each profession’s
contribution to patient care. Moreover, students reported a deeper appreciation of patient-centered approaches and the complexities of
coordinating care across different healthcare roles.
Conclusion: Simulated interprofessional team conferences using cross-training effectively taught junior students to understand the
essence of a good healthcare team and the importance of a patient-centered approach. Cross-training significantly enhanced students’
interprofessional competencies, communication skills, and empathy toward other professions. This case underscores the necessity of
incorporating cross-training into IPE to prepare healthcare professionals for collaborative practice and improve patient outcomes.
Future research should consider expanding the scope to include more diverse scenarios and longitudinal assessments to measure long-
term impacts on professional practice.

Community Pharmacists’ Attitudes and Experiences Regarding the Promotion of Vaccinations in Japan

Iwata H, Kirihara T, Kobayashi N, Nakamura Y, Koike T, Yamaura K

The Keio Journal of Medicine (Keio University School of Medicine)   2025

Research paper (scientific journal), Last author, Accepted

Analysis of Drug-Induced Xerostomia using the Japanese Adverse Drug Event Report Database

Kondo S, Maese M, Ito N, Okamoto Y, Iwata H, Kobayashi N, Yamaura K

BPB Reports (The Pharmaceutical Society of Japan)  8 ( 5 ) 133 - 137 2025

Research paper (scientific journal), Last author, Accepted

Analysis of Factors Affecting Oral Bacterial Counts and Oral Frailty Among Community Pharmacy Users in Japan

Kondo S, Maki K, Hayashi N, Okamoto Y, Iwata H, Kobayashi N, Yamaura K

International Journal of Oral Care (Japanese Society of Oral Care)  25 ( 1 ) 422 2025

Research paper (scientific journal), Last author, Accepted

Use of Dysphagia-Inducing Drugs and Risk of Aspiration Pneumonia: A Cross-Sectional Analysis Using a Japanese Claims Database

Hayashi N, Yoshida M, Maida N, Kondo S, Ogawa M, Iwata H, Kobayashi N, Yamaura K

Drugs Real World Outcomes (Springer Nature)  12 ( 4 ) 607 - 614 2025

Research paper (scientific journal), Last author, Accepted

Sex Differences in Electrolyte Disturbances Among Diuretic Users According to Renal Function and Age

Maida N, Kondo S, Hayashi N, Iwata H, Kobayashi N, Yamaura K

Drug Safety (Springer Nature)  48 ( 10 ) 1149 - 1159 2025

Research paper (scientific journal), Last author, Accepted

Community pharmacist’s perceptions and needs regarding oral health care advice in Japan

Iwata H, Yoshida R, Hayashi N, Kobayashi N, Fujimoto K, Yamaura K

The Keio Journal of Medicine (Keio University School of Medicine)  74 ( 4 ) 205 - 213 2025

Research paper (scientific journal), Last author, Accepted

Practical training reduces aspiration-linked gaps in pressure ulcer education for pharmacy students

Kondo S, Mima R, Okui R, Iwata H, Kawamoto Y, Kobayashi N, Furuta K, Yamaura K

Drug Discoveries & Therapeutics (International Advancement Center for Medicine & Health Research)  19 ( 2 ) 90 - 95 2025

Research paper (scientific journal), Last author, Accepted

口腔乾燥を誘発する薬剤の高齢患者に対する処方実態と要因.

近藤慎吾, 佐野邦大, 林直子, 藤島清太郎, 岩田紘樹, 小林典子, 山浦克典

Drug Discoveries & Therapeutics (International Advancement Center for Medicine & Health Research)  51 ( 6 ) 355 - 365 2025

Research paper (scientific journal), Last author, Accepted

Identification of Issues Related to Enteral Nutrients Using a Database of Near-miss Events from Community Pharmacies

Kondo S, Maese M, Iwata H, Kobayashi N, Yamaura K

The Keio Journal of Medicine (Keio University School of Medicine)  74 ( 2 ) 86 - 95 2025

Research paper (scientific journal), Last author, Accepted

学習成果基盤型の薬学教育モデル・コア・カリキュラムに基づく実務実習の先行導入から実装後の取り組み評価

川添　仁，岩田紘樹，石川春樹，近藤慎吾，地引　綾，横山雄太，小林典子，鈴木小夜，山浦克典，中村智徳

医療薬学 (日本医療薬学会)  50 ( 9 ) 455 - 464 2024.09

Research paper (scientific journal), Accepted

Sex-related differences regarding headache triggered by low barometric pressure in Japan.

Takumi Fujimoto, Hiroki Iwata, Noriko Kobayashi, Shingo Kondo, Katsunori Yamaura

BMC Research Notes (Springer Nature)  17 ( 203 )  2024.07

Research paper (scientific journal), Last author, Accepted

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Purpose: The prevalence of migraine headache is higher in women. Low barometric pressure is a factor in headache triggering, but sex-related differences have not been identified. The purpose of this study was to examine sex-related differences in headache triggered by low barometric pressure. Methods: Study subjects aged 20–49 years were randomly selected from a research company’s (Macromill, Inc.) web panel. Those with chronic migraine or tension-type headache invited to complete a web-based self-administered questionnaire. Logistic regression analysis was performed with the objective variable as the Headache Impact Test-6 (HIT-6) high scores (56 or more) or headache triggered by low barometric pressure. Results: Participants were 332 women and 337 men in the headache population. HIT-6 high scores were associated with age at headache occurrence 20 years or younger (OR: odds ratio 1.85, 95% CI: confidence interval 1.15–2.99, p = 0.012) and headache triggered by low barometric pressure (OR 2.11, 95%CI 1.51–2.94, p < 0.001). Headache triggered by low barometric pressure was significantly associated with women (OR 2.92, 95%CI 2.12–4.02, p < 0.001). Conclusions: Headache triggered by low barometric pressure were related to sex-related differences. It was suggested that a sex-specific treatment approach for headache triggering is needed.

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Changing Role of Pharmacists in Japan and the Utilization of Gender Medicine Leadership Certification

山浦克典

Journal of Gender Medicine (日本性差医学会・医療学会)  1 ( 1 ) 44 - 49 2024.01

Research paper (scientific journal), Single Work, Lead author,  ISSN  2759-2499

腎機能の低下者に対して注意が必要なOTC医薬品の解析

近藤慎吾, 前瀬鞠, 古堅彩子, 岩田紘樹, 小林典子, 山浦克典

薬局薬学 (日本薬局学会)  17 ( 1 ) 126 - 135 2024

Research paper (scientific journal), Last author, Accepted

Lack of information on gender differences in the package inserts of prescription drugs in Japan.

Narumi Maida, Shingo Kondo, Masanori Ogawa, Naoko Hayashi, Hiroki Iwata, Noriko Kobayashi, Katsunori Yamaura

Drug Discoveries & Therapeutics 17 ( 6 ) 396 - 403 2023.12

Research paper (scientific journal), Last author, Accepted

Inhibition of the dorsomedial striatal direct pathway is essential for the execution of action sequences

Anna Kono, Yu Shikano, Kenji F. Tanaka, Katsunori Yamaura, Iku Tsutsui-Kimura

Neuropsychopharmacology Reports  43 ( 3 ) 414 - 424 2023.09

Joint Work, Accepted

実務実習を修了した上級生が関わるセルフメディケーション実習の学修効果

筒井和斗、小林典子、中村友紀、岩田紘樹、山浦克典

薬学教育 (日本薬学教育学会)  7   1 - 7 2023.07

Research paper (scientific journal), Joint Work, Last author, Accepted

実務実習終了時における到達度評価を向上させる要因は何か？

石川春樹、川添　仁、岩田紘樹、中村友紀、地引　綾、横山雄太、小林典子、鈴木小夜、山浦克典、中村智徳

医療薬学 (日本医療薬学会)  49 ( 4 ) 173 - 182 2023.04

Research paper (scientific journal), Joint Work, Accepted