Kobayashi, Noriko

写真a

Affiliation

Faculty of Pharmacy, Department of Pharmacy 医療薬学・社会連携センター　社会薬学部門 ( Shiba-Kyoritsu )

Position

Assistant Professor/Senior Assistant Professor

External Links

Academic Background 【 Display / hide 】

  • 　

    MUSASHINO UNIVERSITY, Correspondance Division Faculty of Human Studies, Department of Human Studies

    University, Graduated

  • 　

    Kyoritsu University of Pharmacy, Faculty of Pharmaceutical Science, 薬学科

    University, Graduated

  • 　

    Graduate School of Musashino University Correspondence Division, Graduate School of Human Studies, Master's Program in Human Studies

    Graduate School, Completed, Master's course

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Academic Degrees 【 Display / hide 】

  • 修士（人間学）, Musashino University, Coursework

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Books 【 Display / hide 】

  • セルフケアとOTC医薬品　改訂2版

    ネオメディカル, 2022.03

    Scope: 99-114

  • セルフケアとOTC医薬品　改訂版

    小林典子　他, ネオメディカル, 2020.03

    Scope: 消化器機能障害に伴う症状　胸やけ・胃もたれ・食欲不振、吐き気・嘔吐,  Contact page： 95-111

  • セルフケアとOTC医薬品

    KOBAYASHI Noriko, ネオメディカル, 2017.03

    Scope: 消化器機能障害に伴う症状　

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Papers 【 Display / hide 】

  • 心不全患者のトリプルワーミー回避に関する歯薬連揆の新規モデル構築の契機となった1例

    前瀬鞠、近藤恒吾、林直子、岩田紘樹、小林典子、岡本侑子、棧木裕紀、漆畑俊哉、山浦克典

     2026

    Research paper (scientific journal), Joint Work, Accepted

  • Use of Dysphagia-Inducing Drugs and Risk of Aspiration Pneumonia: A Cross-Sectional Analysis Using a Japanese Claims Database

    Hayashi N., Yoshida M., Maida N., Kondo S., Ogawa M., Iwata H., Kobayashi N., Yamaura K.

    Drugs Real World Outcomes 12 ( 4 ) 607 - 614 2025.12

    ISSN  21991154

    　View Summary

    Background and Objectives: Oropharyngeal dysphagia (OD), a dysfunction in swallowing food or drink, can result from various diseases and adverse drug reactions. OD is a risk factor for aspiration pneumonia (AP). However, the specific drugs causing OD and their incidence rates are not fully understood. This study aimed to identify drugs associated with OD, their incidence rates, and AP risk factors in patients taking these drugs on the basis of the information provided in package inserts. Methods: This study identified candidate dysphagia-inducing drugs (CDIDs) from Japanese package inserts that listed OD as an adverse reaction. The age, sex, medications, and comorbidities of patients taking CDIDs were analyzed using the JammNet insurance database, purchased from JammNet Co., Ltd. (Tokyo, Japan). Results: Overall, 54 ingredients were identified as CDIDs. Out of 24,276 patients taking CDIDs, 146 (0.6%) were diagnosed with OD and 76 (0.3%) with AP. Among those with AP, 23 patients (30%) also had OD. OD or AP occurred in patients taking 28 (52%) of the 54 target ingredients. In addition, 13 ingredients had an adverse reaction incidence of 1% or greater for either condition. The top five CDIDs with the highest incidence rates for each diagnosis were clobazam, baclofen, zonisamide, tiapride hydrochloride, and topiramate. Incidence rates of OD and AP were significantly higher with multiple CDIDs than with a single drug (p < 0.05). Logistic regression analysis showed that AP occurrence was significantly associated with males, late-stage elderly individuals, a diagnosis of OD, and constipation. Conclusions: The results of this study suggest that careful attention should be given to the risk of AP when prescribing CDIDs, particularly for elderly male patients.

  • Community pharmadsts'attitudes and experiences regarding the p『omotfon of vaccinations in Japan

    Hiroki Iwata, Taiki Kirihara, Noriko Kobayashi, Yuki Nakamura, Tomoko Koike, Katsunori Yamaura

    The Keio Journal of Medicine   2025.11

    Research paper (scientific journal), Joint Work, Accepted

  • Sex Differences in Electrolyte Disturbances Among Diuretic Users According to Renal Function and Age

    Maida N., Kondo S., Hayashi N., Iwata H., Kobayashi N., Yamaura K.

    Drug Safety 48 ( 10 ) 1149 - 1159 2025.10

    ISSN  01145916

    　View Summary

    Introduction: Diuretics are widely used in Japan for the treatment of hypertension and heart failure. Electrolyte disturbance is a common adverse reaction to diuretics and may be life-threatening. Previous studies have shown that diuretic-induced electrolyte disturbance is more common in women. Electrolyte balance is regulated by the kidneys, and renal function tends to decline with advancing age. Objective: The aim of this study was to identify patients at high risk of adverse reactions to diuretics, considering the effects of sex, renal function, and age on susceptibility to diuretic-induced electrolyte disturbance. Methods: Claims data for 67,135 patients on diuretics in Japan were sourced from DeSC Healthcare, Inc. The data covered the period from April 2020 to March 2021. Results: Analysis of patient numbers using the chi-squared test showed that hyperkalemia was more common in men than in women (326 vs. 271; p = 0.003) and that hypokalemia was more common in women than in men (413 vs. 285; p < 0.001). Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated for women considering age and renal function (estimated glomerular filtration rate [eGFR]). In elderly patients aged ≥ 75 years, the odds of developing hypokalemia in women compared to men were 1.47 (95% CI 1.13–1.91) for eGFR 60–30 mL/min/1.73 m<sup>2</sup> and 2.05 (95% CI 1.08–4.10) for eGFR < 30 mL/min/1.73 m<sup>2</sup>. Conclusion: Among women aged ≥ 75 years, those in lower eGFR groups (60–30 and < 30) had higher odds of hypokalemia compared to men. These data highlight the importance of monitoring for adverse reactions to diuretics, particularly hypokalemia, in elderly women with low eGFR.

  • Analysis of drug induced xerostomia using the Japanese Adverse D『ug Event Report Database

    Shingo Kondo、Mari Maese, Nozomi Ito, Yuko Okamoto, Hiroki Iwata, Noriko Kobayashi, Katsunori Yamaura

    BPB Reports 8 ( 5 ) 133 - 137 2025.10

    Research paper (scientific journal), Joint Work, Accepted

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Papers, etc., Registered in KOARA 【 Display / hide 】

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Reviews, Commentaries, etc. 【 Display / hide 】

  • コロナ禍における薬学部の状況

    小林典子

    慶應義塾大学学生部　学生相談室紀要  2021

    Other, Single Work

  • 薬学部における健康つくり教室

    小林典子

    慶應義塾大学学生部　学生相談室紀要  2019

    Other, Single Work

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Presentations 【 Display / hide 】

  • 低栄薔および栄蒼失調診断患者におけるデータペース性羞解析の課題

    前瀬鞠、近藤恨吾、齋藤健、岩田紘樹、小林典子、山浦克典

    [Domestic presentation]  第19回日本性差医学・医狽学会学術集会 (仙台) , 

    2026.01
    , 

    Poster presentation

  • 慶應義塾大学薬学部附属薬局における刻み生薬の逆ざやに関する実態調査

    川本嘉子、小林奏、奥井莉良、演崎冬馬、鶴田奈津子、林直子、近藤慎吾、岩田紘樹、小林 典子、山浦克典

    [Domestic presentation]  第58回日本薬剤師会学術大会, 

    2025.10
    , 

    Poster presentation

  • 薬局来局者における腎機能に注意すぺき薬剤の処方と検査値入手の実態調査

    伊藤希，前瀬鞠，近藤慎吾、岩田紘樹，小林典子、山浦克典

    [Domestic presentation]  第58回日本薬剤師会学術大会（京都）, 

    2025.10
    , 

    Poster presentation

  • 薬局来局者の歯周病スコア及び口腔乾燥とオーラルフレイルの関連性

    近藤慎吾、牧花音、林直子、岩田紘樹、小林典子、松本卓也、山浦克典

    [Domestic presentation]  第34回日本老年学会総会, 

    2025.06
    , 

    Poster presentation

  • 薬局利用者の口腔内細面数に関連する因子の探索

    近藤慎吾、牧花音、林直子、岩田紘樹、小林典子、山浦克典

    [Domestic presentation]  第22回日本口腔ケア学会総会・学術大会, 

    2025.04
    , 

    Poster presentation

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Courses Taught 【 Display / hide 】

  • RESEARCH FOR BACHELOR'S THESIS 1

    2025

  • PRIOR LEARNING FOR CLINICAL PRACTICE 5

    2025

  • PRIOR LEARNING FOR CLINICAL PRACTICE 1

    2025

  • PRE-CLINICAL TRAINING FOR HOSPITAL & COMMUNITY PHARMACY

    2025

  • PRACTICAL LEARNING ON SUPPORTING THE INTELLECTUALLY DISABLED PERSON'S ACTIVITIES

    2025

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