Imaoka, Ayuko

写真a

Affiliation

Faculty of Pharmacy, Department of Pharmacy 臨床薬物動態学講座 (Shiba-Kyoritsu)

Position

Research Associate/Assistant Professor/Instructor

 

Papers 【 Display / hide

  • The influence of temperature on the metabolic activity of CYP2C9, CYP2C19, and CYP3A4 genetic variants in vitro.

    Kojima M, Machida K, Cho S, Watanabe D, Seki H, Shimoji M, Imaoka A, Yamazaki H, Guengerich FP, Nakamura K, Yamamoto K, Akiyoshi T, Ohtani H.

    Xenobiotica. 53 ( 5 ) 357 - 365 2023

    Research paper (scientific journal), Joint Work, Accepted

  • Determination of single-molecule transport activity of OATP2B1 by measuring the number of transporter molecules using electrophysiological approach.

    Yajima K, Akiyoshi T, Sakamoto K, Suzuki Y, Oka T, Imaoka A, Yamamura H, Kurokawa J, Ohtani H.

    J Pharmacol Sci. 153 ( 3 ) 153 - 160 2023

    Research paper (scientific journal), Joint Work, Accepted

  • The effects of jabara juice on the intestinal permeation of fexofenadine.

    Han H, Akiyoshi T, Morita T, Tsuchitani T, Nabeta M, Yajima K, Imaoka A, Ohtani H.

    Biol Pharm Bull. 46 ( 12 ) 1745 - 1752 2023

    Research paper (scientific journal), Joint Work, Accepted

  • Irinotecan-induced gastrointestinal damage alters the expression of peptide transporter 1 and absorption of cephalexin in rats.

    Imaoka A, Hattori T, Akiyoshi T, Ohtani H.

    Biopharm Drug Dispos. 44 ( 5 ) 372 - 379 2023

    Research paper (scientific journal), Joint Work, Lead author, Accepted

  • Comparison of the transport kinetics of fexofenadine and its pH dependency among OATP1A2 genetic variants.

    Han H, Akiyoshi T, Morita T, Kataoka H, Katayama K, Yajima K, Imaoka A, Ohtani H.

    Drug Metab Pharmacokinet.  46 2022

    Research paper (scientific journal), Joint Work, Accepted

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Papers, etc., Registered in KOARA 【 Display / hide

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Presentations 【 Display / hide

  • OATP1A2およびOATP2B1による4',5'-dibromofluorescein輸送特性の比較

    杉村 直紀, 佐々木 希海, 辻井 一成, 今岡 鮎子, 秋好 健志, 大谷 壽一

    日本薬学会第 144 年会, 

    2024.03

    Poster presentation

  • OATP1B1各種遺伝的変異型の単分子輸送特性の比較

    辻井 一成, 矢島 広大, 秋好 健志, 坂本 多穗, 鈴木 良明, 岡 貴之, 今岡 鮎子, 山村 寿男, 黒川 洵子, 大谷 壽一

    日本薬学会第 144 年会, 

    2024.03

    Oral presentation (general)

  • 10種の柑橘果汁の各種フラバノン配糖体含量とOATP1A2/2B1阻害特性に基づく薬物相互作用リスクの評価

    荒井 智貴, 諏訪 円佳, 今岡 鮎子, 秋好 健志, 大谷 壽一

    日本薬学会第 144 年会, 

    2024.03

    Oral presentation (general)

  • OATP2B1遺伝的バリアントの輸送特性に対する温度の影響

    河合 さくら, 荒木 尚哉, 片岡 寛樹, 今岡 鮎子, 秋好 健志, 大谷 壽一

    日本薬学会第 144 年会, 

    2024.03

    Poster presentation

  • Inhibition kinetics of Citrus jabara juice on CYP3A4 and identification of its inhibitory components.

    Koinuma K, Noto K, Morita T, Uekusa Y, F. Peter Guengerich, Nakamura K, Yamamoto K, Imaoka A, Akiyoshi T, Ohtani H

    第33回日本医療薬学会年会, 

    2023.11

    Poster presentation

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Research Projects of Competitive Funds, etc. 【 Display / hide

  • 抗菌薬併用によるアルミニウム吸収亢進の全身曝露評価およびメカニズムの解明

    2020.04
    -
    2023.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Early-Career Scientists , Principal investigator

  • キレート形成による薬物相互作用に関する新規機序の解明と金属吸収亢進のリスクの検討

    2018.04
    -
    2020.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Early-Career Scientists , Principal investigator

Awards 【 Display / hide

  • 優秀発表賞

    2023.06, 柑橘系果物に含有される CYPs 阻害成分の含量とその果実間差の網羅的解析

    Type of Award: Award from Japanese society, conference, symposium, etc.

  • 優秀発表賞

    2022.06, 5-FU 誘発性消化管障害時のマグネシウムの体内動態評価

    Type of Award: Award from Japanese society, conference, symposium, etc.

  • 優秀発表賞

    2021.06, 難溶性薬物の過飽和溶液の安定性に対するウルトラファインバブルの影響

    Type of Award: Award from Japanese society, conference, symposium, etc.

  • 優秀発表賞

    2021.06, クランベリージュースによる消化管 OATPs 阻害活性の検討とその阻害成分の探索

    Type of Award: Award from Japanese society, conference, symposium, etc.

  • 優秀発表賞

    2021.06, CYP2C9 各種遺伝的 variants の代謝活性に対する pH の影響

    Type of Award: Award from Japanese society, conference, symposium, etc.

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Courses Taught 【 Display / hide

  • RESEARCH FOR BACHELOR'S THESIS 1

    2023

  • PRIOR LEARNING FOR CLINICAL PRACTICE 2

    2023

  • PRE-CLINICAL TRAINING FOR HOSPITAL & COMMUNITY PHARMACY

    2023

  • PHARMACEUTICAL-ENGLISH SEMINAR

    2023

  • ENGLISH EXERCISES FOR PHARMACEUTICAL SCIENCES

    2023

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