Hori, Yutaka

写真a

Affiliation

Faculty of Science and Technology, Department of Applied Physics and Physico-Informatics (Yagami)

Position

Associate Professor

Related Websites

Career 【 Display / hide

  • 2013.04
    -
    2013.08

    東京大学大学院, 情報理工学系研究科 システム情報学専攻, 特任研究員

  • 2013.09
    -
    2016.03

    California Institute of Technology, Department of Computing and Mathematical Sciences, Postdoctoral Scholar

  • 2017.04
    -
    2019.03

    Institute of Physical and Chemical Research, 統合生命医科学研究センター統合ゲノミクス研究グループ, 客員研究員

Academic Background 【 Display / hide

  • 2008.03

    The University of Tokyo, 工学部, 計数工学科

    University, Graduated

  • 2010.03

    The University of Tokyo, 情報理工学系研究科, システム情報学専攻

    Graduate School, Completed, Master's course

  • 2013.03

    The University of Tokyo, 情報理工学系研究科, システム情報学専攻

    Graduate School, Completed

Academic Degrees 【 Display / hide

  • 学士(工学), The University of Tokyo, 2008.03

  • 修士(情報理工学), The University of Tokyo, 2010.03

  • 博士 (情報理工学), The University of Tokyo, 2013.03

 

Research Areas 【 Display / hide

  • Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Control and system engineering

Research Keywords 【 Display / hide

  • molecular systems

  • molecular robotics

  • 制御工学

  • 制御理論

  • 合成生物学

 

Papers 【 Display / hide

  • A parametric logistic equation with light flux and medium concentration for cultivation planning of microalgae

    Kazuki Kambe, Yasutaka Hirokawa, Asuka Koshi, Yutaka Hori

    Journal of the Royal Society Interface 19 ( 19 )  2022.06

    Research paper (scientific journal), Joint Work, Last author, Corresponding author, Accepted

  • Instability margin analysis for parametrized LTI systems with application to repressilator

    Hara S., Iwasaki T., Hori Y.

    Automatica (Automatica)  136 2022.02

    ISSN  00051098

     View Summary

    This paper is concerned with a robust instability analysis for the single-input-single-output unstable linear time-invariant (LTI) system under dynamic perturbations. The nominal system itself is possibly perturbed by the static gain of the uncertainty, which would be the case when a nonlinear uncertain system is linearized around an equilibrium point. We define the robust instability radius as the smallest H∞ norm of the stable linear perturbation that stabilizes the nominal system. There are two main theoretical results: one is on a partial characterization of unperturbed nominal systems for which the robust instability radius can be calculated exactly, and the other is a numerically tractable procedure for calculating the exact robust instability radius for nominal systems parametrized by a perturbation parameter. The results are applied to the repressilator in synthetic biology, where hyperbolic instability of a unique equilibrium guarantees the persistence of oscillation phenomena in the global sense, and the effectiveness of our linear robust instability analysis is confirmed by numerical simulations.

  • Finite-Time Stability Analysis for Resource Limited Chemical Reactions

    Matsunaga T., Uemura R., Hori Y.

    IEEE Control Systems Letters (IEEE Control Systems Letters)  5 ( 3 ) 815 - 820 2021.07

     View Summary

    © 2017 IEEE. We consider chemical reaction systems that operate in a resource limited situation such as in a closed test tube. These systems can operate only for a finite interval of time before the system variables deviate from the normal operating region. Thus, in order to characterize the performance of the systems, it is important to analyze the duration of the normal operation, which is closely related to the notion of finite-time stability. In this letter, we propose an algebraic optimization approach to analyze finite-time stability of resource limited chemical reactions. Specifically, we present semidefinite programs that compute guaranteed lower and upper bounds of the duration of the normal operation, which we call survival time, for a given set of uncertain initial concentrations. The proposed semidefinite programs provide progressively tighter bounds of survival time by increasing the variables and constraints, allowing for the tuning of the balance between the computational time and the conservativeness of the bounds. We demonstrate the proposed method using the regenerator circuit of DNA strand displacement reactions.

  • Robust Instability Radius for Multi-agent Dynamical Systems with Cyclic Structure

    Shinji Hara, Tetsuya Iwasaki, Yutaka Hori

     2021.03

    Research paper (international conference proceedings), Joint Work, Accepted

  • Report on BIOMOD JAPAN OPEN 2020

    HORI Yutaka

    Journal of The Society of Instrument and Control Engineers (The Society of Instrument and Control Engineers)  60 ( 1 ) 77 - 77 2021.01

    ISSN  04534662

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Papers, etc., Registered in KOARA 【 Display / hide

Reviews, Commentaries, etc. 【 Display / hide

  • 生体分子を材料とする人工システムの設計と制御 〜生物と人工物をつなぐためのフレームワーク〜

    堀 豊

    計測と制御 60 ( 7 )  2021.07

    Article, review, commentary, editorial, etc. (scientific journal)

  • 確率ゆらぎを利用した生体分子システムの設計

    堀 豊

    計測と制御 60 ( 5 ) 345 - 350 2021.05

    Article, review, commentary, editorial, etc. (scientific journal)

  • Modeling and Analysis of Stochastic Reaction Kinetics in Biomolecular Systems

    Yutaka Hori

    New Generation Computing 38 ( 1 )  2020.05

    Article, review, commentary, editorial, etc. (scientific journal)

  • Control and Biology: Going Beyond the Boundary, and Fusing

    Yutaka Hori

    計測と制御 58 ( 5 ) 323 - 324 2019.05

    Other, Single Work

  • Modeling and Analysis of Stochastic Fluctuations in Biomolecular Systems

    Yutaka Hori

    計測と制御 58 ( 4 ) 253 - 257 2019.04

    Article, review, commentary, editorial, etc. (scientific journal), Single Work

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Presentations 【 Display / hide

  • 双方向型分子通信路のモデル化および周波数応答解析

    小塚太資,堀豊

    第66回システム制御情報学会, 

    2022.05

  • 円形断面マイクロ流路の作製と On-Off バルブへの応用

    上原花織, 堀豊, 石榑崇明

    化学とマイクロ・ナノシステム学会第45回研究会, 

    2022.05

  • 生化学反応系の動的制御のためのケミカルアクチュエータおよび可変容量リアクタ

    白石駿, 茶谷智仁, 宮廻裕樹, 尾上弘晃, 堀豊

    第66回システム制御情報学会, 

    2022.05

  • 離散時間系の学習則を用いたモデルフリー二段階制御器設計法の過渡学習性能の向上

    南芽衣,大川佳寛,佐々木智丈,堀豊

    第9回計測自動制御学会制御部門マルチシンポジウム, 

    2022.03

  • 分子通信の設計のための到達時刻分布を用いた拡散動態シミュレーション法

    原星周, 堀豊

    第34回自律分散システム・シンポジウム, 

    2022.01

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Research Projects of Competitive Funds, etc. 【 Display / hide

  • Distribution-based design of stochastic response in biomolecular systems

    2021.04
    -
    2025.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Principal investigator

  • 再帰性と可塑性を有する分子学習モジュールのシステム設計理論

    2021
    -
    2022

    文部科学省・日本学術振興会, 科学研究費助成事業, Principal investigator

  • 第一原理モデルとデータ駆動型モデルの融合による遺伝子回路のロバスト動態予測

    2018.04
    -
    2022.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Principal investigator

  • Theory and Experimental Setup for Set based Model Identification of Genetic Circuits using Frequency Response

    2016.08
    -
    2018.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Research Activity Start-up , Principal investigator

Intellectual Property Rights, etc. 【 Display / hide

  • 線形予測係数算出装置、線形予測係数算出方法、線形予測係数算出プログラム、および記憶媒体

    Date applied: 2008-051149  2008.02 

    Date announced: 2009-210644  2009.09 

    Date issued: 5057334  2012.08

    Patent, Joint

  • 符号化装置、復号化装置、符号化方法、復号化方法、プログラム、記録媒体

    Date applied: 2008-051150  2008.02 

    Date announced: 2009-210645  2009.09 

    Date issued: 5010293  2012.06

    Patent, Joint

 

Courses Taught 【 Display / hide

  • PRESENTATION TECHNIQUE

    2022

  • MATHEMATICS FOR APPLIED PHYSICS (B)

    2022

  • MATHEMATICAL THEORY IN BIOMOLECULAR SYSTEMS

    2022

  • LABORATORY IN SCIENCE

    2022

  • INDEPENDENT STUDY ON FUNDAMENTAL SCIENCE AND TECHNOLOGY

    2022

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Memberships in Academic Societies 【 Display / hide

  • 計測自動制御学会

     
  • システム制御情報学会

     
  • IEEE

     

Committee Experiences 【 Display / hide

  • 2020.05
    -
    Present

    委員, 計測自動制御学会 ポストコロナ未来社会ワーキンググループ

  • 2020.04
    -
    Present

    専門調査員, 文部科学省 科学技術・学術政策研究所

  • 2020.04
    -
    Present

    委員, 計測自動制御学会 制御部門 理論部会

  • 2020.04
    -
    2021.03

    主査, 計測自動制御学会 知能分子ロボティクス 調査研究会

  • 2019.09
    -
    Present

    Associate Editor, Conference Editorial Board, IEEE Control Systems Society

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