Chida, Noritaka

写真a

Affiliation

Faculty of Science and Technology, Department of Applied Chemistry (Yagami)

Position

Professor

Related Websites

External Links

Career 【 Display / hide

  • 1984.04
    -
    1987.03

    三楽株式会社 中央研究所探索研究部 ,研究員

  • 1987.04
    -
    1992.03

    慶應義塾大学(理工学部) 助手

  • 1988.09
    -
    1989.08

    アメリカ合衆国ペンシルバニア大学化学科博士研究員

  • 1992.04
    -
    1995.03

    慶應義塾大学(理工学部) 専任講師

  • 1995.04
    -
    1997.03

    慶應義塾大学理工学部(応用化学科), 教室幹事

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Academic Background 【 Display / hide

  • 1979.03

    Keio University, Faculty of Engineering, 応用化学科

    University, Graduated

  • 1981.03

    Keio University, Graduate School, Division of Engineering, 応用化学専攻

    Graduate School, Completed, Master's course

  • 1984.03

    Tohoku University, Graduate School, Division of Natural Science, 化学専攻

    Graduate School, Completed, Doctoral course

Academic Degrees 【 Display / hide

  • 理学 , Tohoku University, 1984.03

 
 

Books 【 Display / hide

  • アルカロイドの科学

    CHIDA NORITAKA, 化学同人, 2017.08

    Scope: 第12章 ヒガンバナ科アルカロイドならびにモルヒネの合成

  • ブルース有機化学概説第3版

    CHIDA NORITAKA, 化学同人, 2016.12

    Scope: 16章,17章

  • Molecular Rearrangements in Organic Synthesis

    CHIDA NORITAKA, John Wiley & Sons, Inc., 2015.10

    Scope: Chapter 12, Ferrier Carbocyclization Reaction

  • ブルース有機化学第7版

    CHIDA NORITAKA, 化学同人, 2015.02

    Scope: 21章,22章

  • Comprehensive Chirality

    CHIDA NORITAKA, SATO TAKAAKI, Elsevier, 2012.10

    Scope: 207-239

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Papers 【 Display / hide

  • Copper-Catalyzed Electrophilic Amidation of Organotrifluoroborates with Use of N-Methoxyamides

    Banjo S., Nakasuji E., Meguro T., Sato T., Chida N.

    Chemistry - A European Journal (Chemistry - A European Journal)  25 ( 33 ) 7941 - 7947 2019.06

    ISSN  09476539

     View Summary

    © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim A copper-catalyzed electrophilic amidation of aryltrifluoroborates with use of N-methoxyamides is reported. The reaction shows high functional group compatibility derived from two distinct features: 1) the high stability of the N-methoxyamides and 2) the nonbasic mild conditions in the presence of LiCl. The developed method can also be applied to the synthesis of enamides, which are widely distributed in natural products. Preliminary mechanistic studies suggest that the initial step is the transmetalation of the aryltrifluoroborate by the assistance of LiCl, and the resulting aryl copper intermediate provides the anilide through non-SN2 oxidative addition to the N-methoxyamide and subsequent reductive elimination.

  • Approach to Fully Substituted Cyclic Nitrones from N-Hydroxylactam Derivatives: Development and Application to the Total Synthesis of Cylindricine C

    Hiraoka S., Matsumoto T., Matsuzaka K., Sato T., Chida N.

    Angewandte Chemie - International Edition (Angewandte Chemie - International Edition)  58 ( 13 ) 4381 - 4385 2019.03

    ISSN  14337851

     View Summary

    © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim An approach to cyclic nitrones from N-hydroxylactam derivatives is documented. The nucleophilic addition of an organolithium reagent to an N-OSEM [SEM=2-(trimethylsilyl)ethoxymethyl] lactam forms a five-membered chelated intermediate, which undergoes both elimination and deprotection to give a fully substituted nitrone in a one-pot process. When combined with the N-oxidation of easily available chiral lactams, this method becomes especially useful for the quick synthesis of chiral nitrones in enantio-pure form, enabling the concise total synthesis of cylindricine C.

  • Asymmetric Total Synthesis of Fasicularin by Chiral N-Alkoxyamide Strategy

    Yamamoto S., Komiya Y., Kobayashi A., Minamikawa R., Oishi T., Sato T., Chida N.

    Organic Letters (Organic Letters)  21 ( 6 ) 1868 - 1871 2019.03

    ISSN  15237060

     View Summary

    © 2019 American Chemical Society. The asymmetric total synthesis of fasicularin is reported. The key to success is the use of a chiral N-alkoxyamide to control both reactivity and stereoselectivity. This functional group enables the aza-spirocyclization and the reductive Strecker reaction, which cannot be realized with an ordinary amide. In addition, use of the chiral alkoxy group establishes two consecutive stereocenters in the aza-spirocyclization through remote stereocontrol.

  • Unified Total Synthesis of Madangamine Alkaloids

    Suto T., Yanagita Y., Nagashima Y., Takikawa S., Kurosu Y., Matsuo N., Miura K., Simizu S., Sato T., Chida N.

    Bulletin of the Chemical Society of Japan (Bulletin of the Chemical Society of Japan)  92 ( 3 ) 545 - 571 2019

    ISSN  00092673

     View Summary

    © 2019 The Chemical Society of Japan. All rights reserved. The full details of a unified total synthesis of madangamine alkaloids are disclosed. Our central strategy is based on the construction of a common ABCE-tetracyclic system, followed by the late-stage installation of various D-rings. The common intermediate is assembled through N-acyliminium cyclization of a propargylsilane, and formation of the (Z,Z)-skipped diene. Stereoselective synthesis of the (Z,Z)-skipped diene is especially challenging, and is accomplished by the combination of Z-selective hydroboration of the 1,1-disubstituted allene and subsequent Migita-Kosugi-Stille coupling. Macrocyclic alkylation enables the late-stage variation of the D-rings on the common tetracyclic intermediate, resulting in the collective total syntheses of madangamines AE. The synthetic madangamine alkaloids exhibited inhibitory activities against a variety of human cancer cell lines.

  • Total synthesis of (–)-zephyranthine

    Ishii K., Seki-Yoritate Y., Ishibashi M., Liaw M., Oishi T., Sato T., Chida N.

    Heterocycles (Heterocycles)  99 ( 1 ) 111 - 117 2019

    ISSN  03855414

     View Summary

    © 2019 The Japan Institute of Heterocyclic Chemistry – Stereoselective total synthesis of (–)-zephyranthine 1 based on the chiral pool approach starting from D-arabinose is described. The three consecutive chiral centers in (–)-zephyranthine were effectively constructed by the sequential [3,3] sigmatropic rearrangements (Claisen, Overman, and Claisen rearrangements) with chirality transfer of the hydroxy groups in D-arabinose.

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Papers, etc., Registered in KOARA 【 Display / hide

Presentations 【 Display / hide

  • Reductive Approach to Nitrones from N-Siloxyamides and N-Hydroxyamides

    Seiya Katahara, Kanami Fujita, Shoichiro Kobayashi, Tsutomu Matsumoto, Takaaki Sato, Noritaka Chida

    日本化学会第98春季年会(日本大学理工学部船橋キャンパス,千葉県船橋市, 2018.03, Oral Presentation(general)

  • ロバタミド類の合成研究

    CHIDA NORITAKA

    日本化学会第98春季年会(日本大学理工学部船橋キャンパス,千葉県船橋市), 2018.03, Oral Presentation(general)

  • カリシフィリン B 二環性骨格の構築

    CHIDA NORITAKA

    日本化学会第98春季年会(日本大学理工学部船橋キャンパス,千葉県船橋市), 2018.03, Oral Presentation(general)

  • Unified Total Synthesis of Stemoamide-type Alkaloids Featuring Chemoselective Assembly of Five-membered Building Blocks

    Makoto Yoritate, Yoshito Takahashi, Hayato Tajima, Chisato Ogihara, Yasuki Soda, Takashi Yokoyama, Takeshi Oishi, Takaaki Sato, Noritaka Chida

    日本化学会第98春季年会(日本大学理工学部船橋キャンパス,千葉県船橋市), 2018.03, Oral Presentation(general)

  • イリジウム触媒を用いた二級アミド基の還元的求核付加反応

    CHIDA NORITAKA

    日本化学会第98春季年会(日本大学理工学部船橋キャンパス,千葉県船橋市), 2018.03, Oral Presentation(general)

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Research Projects of Competitive Funds, etc. 【 Display / hide

  • 全窒素糖の合成と機能探索

    2019.06
    -
    2022.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 千田 憲孝, Grant-in-Aid for Challenging Research (Exploratory) , Principal Investigator

  • Development of the efficient synthetic methods of multi-cyclic biologically active natural products

    2018.04
    -
    2021.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 千田 憲孝, Grant-in-Aid for Scientific Research (B), Principal Investigator

  • Synthetic Study of Biologically Active Natural Products Based on the Novel Chiral Pool Approach

    2014.04
    -
    2018.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 千田 憲孝, Grant-in-Aid for Scientific Research (B), Principal Investigator

Awards 【 Display / hide

  • BCSJ Award Article

    2015.04, The Chemical Society of Japan, Total Synthesis of (+/-)-Gephyrotoxin and (+/-)-Perhydrogephyrotoxin

  • BCSJ Award Article

    CHIDA NORITAKA, 2002.09, The Chemical Society of Japan, Total Synthesis of (+)-Myriocin and (-)-Sphingofungin E from Aldohexoses Using Overman Rearrangement as the Key Reaction

 

Courses Taught 【 Display / hide

  • ADVANCED ORGANIC CHEMISTRY

    2019

  • BACHELOR'S THESIS

    2019

  • BASIC ORGANIC CHEMISTRY

    2019

  • GRADUATE RESEARCH ON FUNDAMENTAL SCIENCE AND TECHNOLOGY 1

    2019

  • GRADUATE RESEARCH ON FUNDAMENTAL SCIENCE AND TECHNOLOGY 2

    2019

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Social Activities 【 Display / hide

  • Sato Yo International Scholarship Foundation

    2005.10
    -
    Present

Memberships in Academic Societies 【 Display / hide

  • 天然有機化合物討論会, 

    2012.10
    -
    Present
  • 天然物化学談話会, 

    1997.10
    -
    2009.09
  • 天然物化学談話会, 

    1995.03
    -
    1995.08
  • 天然物化学談話会, 

    1991.10
    -
    1997.09
  • American Chemical Society, 

    1982.04
    -
    Present

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Committee Experiences 【 Display / hide

  • 2020.03
    -
    Present

    天然物化学・生命科学ディビジョン主査 , 公益社団法人日本化学会

  • 2016.07
    -
    2017.03

    学会賞選考委員会委員, 公益社団法人日本化学会

  • 2016.05
    -
    2017.03

    第97春季年会 会場・総務小委員会委員長, 公益社団法人日本化学会

  • 2016.05
    -
    2017.03

    第97春季年会実行委員会委員, 公益社団法人日本化学会

  • 2016.03
    -
    2020.02

    天然物化学・生命科学ディビジョン副主査, 公益社団法人 日本化学会

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