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Affiliation
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Faculty of Science and Technology, Department of Applied Chemistry (Yagami)
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Position
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Professor
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Related Websites
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Simizu, Siro
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My research interests are glycoscience, cancer cell biology and chemical biology.
Keio University, Faculty of Science and Engineering, Department of Applied Chemistry
University, Graduated
Keio University, Graduate School, Division of Science and Engineering
Graduate School, Completed, Doctoral course
Nanotechnology/Materials / Bio chemistry
Life Science / Molecular biology
実験医学
宮崎 功、奥村 英夫、清水 史郎、長田 裕之, 2011
Scope: 79-83
化学と工業
叶 直樹、清水 史郎, 2011
Scope: 37-39
Saegusa J., Osada Y., Miura K., Sasazawa Y., Ogura A., Takao K.i., Simizu S.
Bioorganic and Medicinal Chemistry Letters (Bioorganic and Medicinal Chemistry Letters) 60 2022.03
ISSN 0960894X
Scalable Syntheses and Biological Evaluation of Africane-Type Sesquiterpenoids
Matsuda Y., Koyama T., Kawano S., Miura K., Simizu S., Saikawa Y., Nakata M.
Chemistry and Biodiversity (Chemistry and Biodiversity) 19 ( 3 ) 2022.03
ISSN 16121872
ErbB4-mediated regulation of vasculogenic mimicry capability in breast cancer cells
Kawahara R., Simizu S.
Cancer Science (Cancer Science) 113 ( 3 ) 950 - 959 2022.03
ISSN 13479032
Methionine aminopeptidase-2 is a pivotal regulator of vasculogenic mimicry
Shimizu S., Kawahara R., Simizu S.
Oncology Reports (Oncology Reports) 47 ( 2 ) 2022.02
ISSN 1021335X
Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer
Mizuta H., Okada K., Araki M., Adachi J., Takemoto A., Kutkowska J., Maruyama K., Yanagitani N., Oh-hara T., Watanabe K., Tamai K., Friboulet L., Katayama K., Ma B., Sasakura Y., Sagae Y., Kukimoto-Niino M., Shirouzu M., Takagi S., Simizu S., Nishio M., Okuno Y., Fujita N., Katayama R.
Nature Communications (Nature Communications) 12 ( 1 ) 2021.12
Identification of novel enzymes for C-mannosylation and analysis of its substrate proteins
Simizu, Sirō
科学研究費補助金研究成果報告書 2020
Development of novel drug for bone-related diseases using Pirin inhibitors
Simizu, Siro
科学研究費補助金研究成果報告書 2014
Vasculogenic mimicry: A dynamic event of malignancy
Simizu S.
Biochimica et Biophysica Acta - General Subjects (Biochimica et Biophysica Acta - General Subjects) 1866 ( 3 ) 2022.03
ISSN 03044165
C-Mannosylation: Previous studies and future research perspectives
Niwa Y., Simizu S.
Trends in Glycoscience and Glycotechnology (Trends in Glycoscience and Glycotechnology) 30 ( 177 ) E231 - E238 2018.11
ISSN 09157352
C-Mannosylation: Previous studies and future research perspectives
Niwa Y., Simizu S.
Trends in Glycoscience and Glycotechnology (Trends in Glycoscience and Glycotechnology) 30 ( 177 ) 2018.11
ISSN 09157352
R-spondin1 におけるリン酸化の機能解析
西谷 拓海, 鈴木 健裕, 丹羽 祐貴, 三浦 一輝, 堂前 直, 清水 史郎
日本農芸化学会関東支部会2018年度大会 (千葉) ,
Poster presentation
Vibsanin A誘導体の生物活性評価および標的分子の同定
三浦 一輝、松木 渉、高尾 賢一、清水 史郎
日本農芸化学会関東支部会2018年度大会 (千葉) ,
Poster presentation
ヒトC型糖転移酵素DPY19L3のプロモーター解析
吉本 哲、三浦 一輝、清水 史郎
日本農芸化学会関東支部会2018年度大会 (千葉) ,
Poster presentation
トポロジー解析によるDPY19L1のC-mannosyltransferase活性中心の探索
横山 典弘, 柳原 凌太郎, 三浦 一輝, 丹羽 祐貴, 清水 史郎
日本農芸化学会関東支部会2018年度大会 (千葉) ,
Poster presentation
C-mannosylation-基質と酵素の探索
清水 史郎
日本農芸化学会中部支部 第183回例会 (名古屋) ,
Symposium, workshop panel (nominated)
Role of C-mannosylation in zebrafish and development of inhibitors for C-mannosylation
基盤研究(C), Principal investigator
新たなC型糖修飾責任酵素の同定と基質タンパク質の解析
MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Principal investigator
日本がん転移学会 研究奨励賞
SIMIZU Siro, 2012.07, 日本がん転移学会, ケミカルバイオロジーによる転移関連分子の理解と制御
Type of Award: Award from Japanese society, conference, symposium, etc.
B.B.B.論文賞
MIYAZAKI Isao, SIMIZU Siro, ICHIMIYA Harumi, KAWATANI Makoto, OSADA Hiroyuki, 2009.03, 日本農芸化学会, Robust and systematic drug screening method using chemical arrays and the protein library: identification of novel inhibitors of carbonic anhydrase II
Type of Award: Award from Japanese society, conference, symposium, etc.
日本癌学会奨励賞
SIMIZU Siro, 2004.10, 日本癌学会, 薬剤耐性・転移に関与するがん分子標的の機能解析
Type of Award: Award from Japanese society, conference, symposium, etc.
MICROBIOLOGY
2024
LABORATORIES IN APPLIED CHEMISTRY D
2024
INDEPENDENT STUDY ON FUNDAMENTAL SCIENCE AND TECHNOLOGY
2024
GRADUATE RESEARCH ON FUNDAMENTAL SCIENCE AND TECHNOLOGY 2
2024
GRADUATE RESEARCH ON FUNDAMENTAL SCIENCE AND TECHNOLOGY 1
2024
The Japanese Society of Carbohydrate Research,
日本がん分子標的治療学会,
日本ケミカルバイオロジー学会,
日本がん転移学会,
日本癌学会,
Member, 日本がん転移学会
Board of Councillors, 日本がん分子標的治療学会
Member, 日本ケミカルバイオロジー学会
Member, 日本癌学会