Miki, Norihisa

写真a

Affiliation

Faculty of Science and Technology, Department of Mechanical Engineering (Yagami)

Position

Professor

Profile Summary 【 Display / hide

  • '''''''MEMS (MicroElectroMechanical Systems) Technology has enabled manufacturing of micro/nanoscale structures. A wide variety of sensors, actuators, and chemical/bio chips have been developed by exploiting the virtues of their small sizes and scale effects. Our laboratory focuses on innovative micro/nano-fabrication technologies, human-interface devices, micro-fluidic devices utilized for bio/medical applications, and power MEMS devices.'''''''

Career 【 Display / hide

  • 2001.04
    -
    2003.03

    Postdoctoral Associate, Dept. of Aeronautics and Astronautics, Massachusetts Institute of Technology, USA

  • 2003.04
    -
    2004.03

    Research Engineer, Dept. of Aeronautics and Astronautics, Massachusetts Institute of Technology, USA

  • 2006.12
    -
    2009.03

    神奈川科学技術アカデミー非常勤研究員

  • 2008.07
    -
    2010.03

    大学院FD委員会委員

  • 2008.07
    -
    2013.03

    LifeBEANS Center, BEANS Laboratory

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Academic Background 【 Display / hide

  • 1996.03

    The University of Tokyo, Faculty of Engineering, Department of Mechanical Engineering

    University, Graduated

  • 2001.03

    The University of Tokyo, Graduate School, Division of Engineering, Mechano-Informatics

    Graduate School, Completed, Doctoral course

Academic Degrees 【 Display / hide

  • 博士(工学), The University of Tokyo, Coursework, 2001.03

 

Research Areas 【 Display / hide

  • Informatics / Mechanics and mechatronics (Intelligent Mechanics/Mechanical System)

  • Informatics / Robotics and intelligent system (Intelligent Mechanics/Mechanical System)

Research Keywords 【 Display / hide

  • MEMS

  • Interaction

  • Human Interface

  • Healthcare

  • Micro/Nano

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Books 【 Display / hide

  • 透過式ウェアラブル視線検出システムを用いたヒトモニタリング

    三木則尚, 2018.02

    Scope: VR/AR技術の開発動向と最新応用事例 第6章第4節 pp.251-260

  • 色素増感素子を用いた透過式ウェアラブル視線検出システム、ウェアラブル・エレクトロニクス

    三木則尚, 株式会社エヌ・ティー・エス, 2014.06

  • ナノテクノロジーを用いたマイクロダイアライザーの開発, 全人力・科学力・透析力 for the people 透析医学

    菅野義彦, 三木則尚, 医薬ジャーナル社, 2014.06

    Scope: pp. 202-204

  • Advances in Micro/Nano Electromechanical Systems and Fabrication Technologies

    Norihisa Miki, INTECH, 2013

  • Advanced Bio/Medical Devices and Equipments for Health Care

    MIKI NORIHISA, シーエムシー出版, 2009.05

    Scope: 37-52

     View Summary

    患者のQOLを向上する医療に貢献するマイクロデバイスとして、カプセル型内視鏡の電源となる胃酸発電池、携帯できる人工透析デバイスを紹介した。

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Papers 【 Display / hide

  • Machine-Learning-Based Fine Tuning of Input Signals for Mechano-Tactile Display

    Shuto Yamanaka,Tatsuho Nagatomo,Takefumi Hiraki,Hiroki Ishizuka, Norihisa Miki

    Sensors (MDPI)  22 ( 14 ) 5299 2022.07

    Research paper (scientific journal), Joint Work, Last author, Corresponding author, Accepted

  • Pressure-controlled ultrasound probe for reliable imaging in breast cancer diagnosis

    Yukina Matsumoto, Ayu Katsumura and Norihisa Miki

    Japanese Journal of Applied Physics (IOP)  61   SD1035 2022.05

    Research paper (scientific journal), Joint Work, Last author, Accepted

  • Study Effect of nAg Particle Size on the Properties and Antibacterial Characteristics of Polysulfone Membranes

    Prihandana G.S., Sriani T., Muthi’ah A.D., Machmudah A., Mahardika M., Miki N.

    Nanomaterials (MDPI)  12 ( 3 ) 388 2022.01

    Research paper (international conference proceedings), Joint Work, Last author, Accepted

     View Summary

    Polysulfone ultrafiltration membranes were fabricated using various sizes (20, 40, and 90–210 nm) of silver nanoparticles (nAg) blended in a dope solution. To characterize the performance and properties of the prepared membranes, scanning electron microscopy (SEM), water contact angle, protein separation, water flux, and antibacterial tests were conducted. The characterization results revealed that when nAg particles (20 nm) were blended into the base polymer PSF, the PSF/nAg blended membrane had the lowest contact angle (58.5◦ ) and surface energy (110.7 mN/m). When experimenting with ultrafiltration using protein solutions, bare PSF and PSF/nAg-20 blended membranes gave similar values of protein rejection: 93% of bovine serum albumin (BSA) and 70% of lysozyme rejection. Furthermore, SEM studies showed that the surface pore size was reduced by adding 20 nm nAg particles in the casting solution. Most importantly, the introduction of 40 nm nAg particles reduced the growth of bacterial colonies on the membrane surface by up to 72%. These findings revealed that nAg particles are expected to be a potential modifier for the fabrication of an ultrafiltration membrane.

  • Direct Wiring of Liquid Metal on an Ultrasoft Substrate Using a Polyvinyl Alcohol Lift-off Method

    Murakami K., Tochinai R., Tachibana D., Isano Y., Matsuda R., Nakamura F., Kurotaki Y., Isoda Y., Yamane M., Sugita Y., Fukuda J., Ueno K., Miki N., Fuchiwaki O., Ota H.

    ACS Applied Materials and Interfaces (ACS Applied Materials and Interfaces)  14 ( 5 ) 7241 - 7251 2022.02

    Research paper (scientific journal), Accepted,  ISSN  19448244

     View Summary

    In recent years, wiring and system construction on ultrasoft materials such as biological tissues and hydrogels have been proposed for advanced wearable devices, implantable devices, and soft robotics. Among the soft conductive materials, Ga-based liquid metals (LMs) are both biocompatible and ultrasoft, making them a good match for electrodes on the ultrasoft substrates. However, gels and tissues are softer and less wettable to the LMs than conventional soft substrates such as Ecoflex and polydimethylsiloxane. In this study, we demonstrated the transfer of LM paste composed of Ga-based LM and Ni nanoparticles onto ultrasoft substrates such as biological tissue and gels using sacrificial polyvinyl alcohol (PVA) films. The LM paste pattern fabricated on the PVA film adhered to the ultrasoft substrate along surface irregularities and was transferred without being destroyed by the PVA film before the PVA's dissolution in water. The minimum line width that could be wired was approximately 165 μm. Three-dimensional wiring, such as the helical structure on the gel fiber surface, is also possible. Application of this transfer method to tissues using LM paste wiring allowed the successful stimulation of the vagus nerve in rats. In addition, we succeeded in transferring a temperature measurement system fabricated on a PVA film onto the gel. The connection between the solid-state electrical element and the LM paste was stable and maintained the functionality of the temperature-sensing system. This fundamental study of wiring fabrication and system integration can contribute to the development of advanced electric devices based on ultrasoft substrates.

  • Pump‐Free Microfluidic Hemofiltration Device

    Takahiro Ito, Takashi Ota, Rei Kono, Yoshitaka Miyaoka, Hidetoshi Ishibashi, Masaki Komori, Akio Yasukawa, Yoshihiko Kanno, and Norihisa Miki

    Micromachines (MDPI)  12   992 2021.08

    Research paper (scientific journal), Joint Work, Accepted

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Papers, etc., Registered in KOARA 【 Display / hide

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Reviews, Commentaries, etc. 【 Display / hide

  • ソルトチップでおいしく減塩

    三木則尚

    臨床栄養 (医歯薬出版株式会社)  132 ( 2 ) 138 - 139 2018.02

    Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media), Single Work

  • 体内植込み式人工腎臓の現況と未来

    三木 則尚、菅野義彦

    腎臓内科・泌尿器科 (科学評論社)  5 ( 5 ) 482 - 487 2017.05

    Article, review, commentary, editorial, etc. (scientific journal), Joint Work

  • マイクロ・ナノ医療デバイス実用化への課題─インプラント人工透析システムを例に─

    三木 則尚

    エレクトロニクス実装学会誌 20 ( 2 ) 109 - 112 2017.03

    Article, review, commentary, editorial, etc. (scientific journal), Single Work

  • Electrospray formation of ring-shaped silica nanoparticles

    Kazuhiro Uchida, Kazuhiko Higashi, Koichi Hishida, Atsushi Hotta,Norihisa Miki

    Japanese Journal of Applied Physics Rapid Communications 54   020302 2015.01

    Rapid communication, short report, research note, etc. (scientific journal), Joint Work

  • MEMS-based Tactile Displays

    H. Ishizuka & N. Miki

    Displays (Elsevier)  37   25 - 32 2015

    Article, review, commentary, editorial, etc. (scientific journal), Joint Work

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Presentations 【 Display / hide

  • Electroencephalogram Measurement in Adapting Process to Inverse Vision

    T.Onomoto, Y. Yoshida, N. Miki

    International Conference on Electronics Packaging(ICEP2019) (Niigata, Japan) , 

    2019.04

    Oral presentation (general)

  • Long-term in vivo Experiment Protocol Using SD Rats

    T.Ito, Y.Koya, N.Miki

    International Conference on Electronics Packaging(ICEP2019) (Niigata, Japan) , 

    2019.04

    Oral presentation (general)

  • Azinzo Project

    A.Watanabe, N.Miki

    Hellow Tomorrow Global Summit (Paris, France) , 

    2019.03

    Oral presentation (general)

  • A Precise Sampling Strip with Microstructures

    H.Kamiya, T.Ohta, H.Yasuga, N.Miki

    40th International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC2018), 

    2018.07

    Oral presentation (general)

  • Microbes culture systems using cellulose tubes and photocatalyst-coated glass balls

    K.Saito, K.Fujimoto, K.Higashi, N.Miki

    40th International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC2018), 

    2018.07

    Oral presentation (general)

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Research Projects of Competitive Funds, etc. 【 Display / hide

  • Objective and Quantitative Assessment of Reproduction of Tactile Feeling

    2020.04
    -
    2024.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Principal investigator

  • 同期する脳を用いた協働場の評価と創成 双方向脳神経科学の開拓研究

    2019.06
    -
    2021.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Challenging Research (Exploratory) , Principal investigator

  • Approach to inverse problems of tactile display using tactile samples

    2018.04
    -
    2020.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas, Principal investigator

  • Jisso Technologies for Micro-Nano Medical Devices

    2015.04
    -
    2018.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Principal investigator

  • 単結晶ダイヤモンドのパラレルプロセッシングによる超微細工具開発研究

    2008.04
    -
    2010.03

    厚生労働科学研究費補助金 財団法人みずほ学術振興財団研究助成, Research grant, No Setting

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Works 【 Display / hide

  • 第105回マイクロ接合研究委員会「医療用マイクロ・ナノデバイスのための加工・表面処理技術 - マイクロ透析システムを例をとって –」

    三木 則尚

    2013.11
    -
    Present

    Other, Single

  • MEMS実装パッケージング・フォーラム,ナノ・マイクロビジネス展「医療用MEMSの人工透析システムへの応用」

    三木 則尚

    2013.07
    -
    Present

    Other, Single

  • 新川崎創造のもりキャンパス オープンセミナー 「人に関わるMEMS :医療からICTまで」

    三木 則尚

    2012.03
    -
    Present

    Other, Single

  • 第90回慶應医学会総会・シンポジウム「マイクロ流体システムを用いた超小型透析装置の開発」

    MIKI NORIHISA

    2010.11
    -
    Present

    Other, Single

  • 第19回MEMSPCカフェ「ポリマー材料の特性を生かした高機能マイクロデバイス」

    MIKI NORIHISA

    2010.10
    -
    Present

    Other, Single

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Intellectual Property Rights, etc. 【 Display / hide

  • 瞳検出方法、瞳位置検出装置及び透過型視線検出装置

    Date applied: 特願2006-018591  2006.01 

    Date announced: 特開2007-195775  2007.08 

    Patent, Joint

  • 表面増強ラマン分光分析用基板の作成方法及び表面増強ラマン分光分析用基板

    Date applied: 特願2006-018555  2006.01 

    Date announced: 特開2007-198933  2007.08 

    Patent, Joint

  • 体内飲み込み型発電池

    Date applied: 特願2006-018571  2006.01 

    Date announced: 特開2007-200739  2007.08 

    Patent, Joint

  • 血液濾過装置

    Date applied: 特願2016-046355  2016.03 

    Patent, Joint

  • 液滴アレイ形成用のマイクロウェルプレート及び液滴アレイの製造方法

    Date applied: 2016-127183  2016 

    Patent, Joint

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Awards 【 Display / hide

  • 日本機械学会マイクロ・ナノ工学部門優秀講演論文表彰

    2022.02, 日本機械学会マイクロ・ナノ工学部門

    Type of Award: Award from Japanese society, conference, symposium, etc.

  • 次世代リーダービジネスプランコンテスト 特別賞

    2020.08

    Type of Award: Award from Japanese society, conference, symposium, etc.

  • 日本機械学会マイクロ・ナノ工学部門貢献表彰

    2019.11, 日本機械学会マイクロ・ナノ工学部門

    Type of Award: Award from Japanese society, conference, symposium, etc.

  • SI2016優秀講演賞

    石塚裕己、畑田龍平、三木則尚, 2016.12, 第17回公益社団法人計測自動制御学会 システムインテグレーション部門講演会

    Type of Award: Award from Japanese society, conference, symposium, etc.

  • 日本機械学会マイクロ・ナノ工学部門優秀講演論文表彰

    荒井都子、工藤優汰、三木則尚, 2016.12, 日本機械学会マイクロ・ナノ工学部門

    Type of Award: Award from Japanese society, conference, symposium, etc.

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Other 【 Display / hide

  • 2017年10月

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    日経新聞 人工腎臓

  • 2017年10月

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    NHKテキスト きょうの健康 2017年11月号
    研究室訪問

  • 2017年09月

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    朝日新聞 人工腎臓

  • 2017年08月

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    朝日新聞夕刊 塩チップおいしく減塩

  • 2017年08月

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    日経夕刊1面 「十分な塩味演出 歯の裏にチップ」

 

Courses Taught 【 Display / hide

  • SPECIAL LECTURE SERIES ON MULTIDISCIPLINARY AND DESIGN SCIENCE

    2022

  • PROJECT LABORATORY IN MECHANICAL ENGINEERING

    2022

  • PRECISION MACHINING

    2022

  • MEMS: DESIGN AND FABRICATION

    2022

  • INTRODUCTION TO INTERDISCIPLINARY SCIENCE AND TECHNOLOGY

    2022

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Social Activities 【 Display / hide

  • NEDO技術委員

    2015.07
    -
    2017.03
  • ナノテクノロジー・材料技術分野の技術ロードマップ策定に関する調査 ヘルスケア材料ワーキンググループ委員

    2015.01
    -
    2015.03
  • 独立行政法人科学技術振興機構研究開発戦略センター「電子情報通信分野俯瞰プロジェクトⅤ」未来研究開発検討委員会

    2011.08
    -
    Present
  • 「異分野融合型次世代デバイス製造技術開発プロジェクト」に関するシミュレーション委員会・財団法人マイクロマシンセンターBEANSプロジェクト

    2008.07
    -
    2013.03
  • NEDO MEMSの技術戦略等検討委員会

    2007.11
    -
    2008.03

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Memberships in Academic Societies 【 Display / hide

  • Micro Nano Processing Conference (MNC2013), 

    2012.10
    -
    Present
  • MEMS 2014, 

    2013.04
    -
    Present
  • Transducers 2013, 

    2012.10
    -
    Present
  • 日本機械学会ロボメカ部門, 

    2013.03
    -
    2013.04
  • 日本機械学会, 

    2012.04
    -
    2013.03

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Committee Experiences 【 Display / hide

  • 2022.04
    -
    2023.03

    副部門長, 日本機械学会マイクロ・ナノ工学部門

  • 2020.04
    -
    2021.03

    アセアン工学系高等教育ネットワークプロジェクト・フェーズ4分野幹事大学委員会委員, 独立行政法人 国際協力機構

  • 2018.04
    -
    2019.12

    実行委員長, 日本機械学会マイクロ・ナノ工学部門 第9回マイクロ・ナノ工学シンポジウム

  • 2018.01
    -
    Present

    評議員, 日本医工ものづくりコモンズ

  • 2017.11
    -
    2018.09

    幹事, 平成30年度E部門総合研究会論文委員会

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