KEIO RESEARCHERS INFORMATION SYSTEM

Papers, etc., Registered in KOARA 【 Display / hide 】

Papers, etc., Registered in KOARA 【 Display / hide 】

• Deep learning-based automated prediction system for pluripotent stem cell-derived cardiomyocytes

  Kusumoto, Dai

  学事振興資金研究成果実績報告書 （慶應義塾大学)  2021

• Deep learning-based automated prediction system for pluripotent stem cell-derived cardiomyocytes

  Kusumoto, Dai

  学事振興資金研究成果実績報告書 （慶應義塾大学)  2020

• 深層学習を用いたiPS細胞由来血管内皮細胞自動認識システム

  Kusumoto, Dai

  （慶應義塾大学大学院医学研究科)  2018

• The exploratory research to investigate the novel anti-atherosclerotic factor using iPS cells

  Kusumoto, Dai

  科学研究費補助金研究成果報告書 2016

• Disease modeling for mitochondrial disease using MELAS specific induced pluripotent stem cells

  Kusumoto, Dai

  科学研究費補助金研究成果報告書 2014

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Research Projects of Competitive Funds, etc. 【 Display / hide 】

Research Projects of Competitive Funds, etc. 【 Display / hide 】

• Development of anti- atherosclerotic drugs using deep learning- based image analysis

  2019.04

  -

  2022.03

  MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Principal investigator

• The exploratory research to investigate the novel anti-atherosclerotic factor using iPS cells

  2014.04

  -

  2017.03

  MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B), Principal investigator

  　View Summary

  Throughout our lives, we are exposed to cellular stress, which causes age-related diseases, such as metabolic syndromes, atherosclerosis, and cancer. Although we have evolved several innate protective mechanisms from cellular stress, the damage is often cumulative and irreversible. However, in rare cases, patients with strong chronic stress such as uncontrolled diabetes, exhibit minimal organ damage, suggesting that they would have strong innate protective mechanisms. Although there are several methods of genetic analysis, including genome-wide association study and exome sequencing, the vascular protective mechanisms are still unknown.
  In this study, we used the endothelial cells (ECs) derived from induced pluripotent stem cells (iPSCs) of severe diabetic patients with mild atherosclerosis to examine these innate protective mechanisms and explore a molecular target, to propose a novel vascular protective mechanism against cellular stresses.

Courses Taught 【 Display / hide 】

Courses Taught 【 Display / hide 】

• RESEARCH FRONTIERS IN BIOMEDICAL SCIENCE

  2024

• RESEARCH FRONTIERS IN BIOMEDICAL SCIENCE

  2023

• RESEARCH FRONTIERS IN BIOMEDICAL SCIENCE

  2022