Yamada, Yoshitake

写真a

Affiliation

School of Medicine, Department of Radiology (Diagnostic Radiology) (Shinanomachi)

Position

Assistant Professor/Senior Assistant Professor

External Links

Profile 【 Display / hide

  • Sep 2005-present: Board Certified Membership of the Japanese Society of Internal Medicine
    Sep 2010-present: Board Certified Diagnostic Radiologist of the Japan Radiological Society
    Aug 2013-present: Specialist in Positron Emission Tomography in the Japanese Board of Nuclear Medicine
    July 2015-present: Specialist in the Japanese Board of Nuclear Medicine
    October 2018-present: Board Certified Fellow of the Japan Society of Ultrasonics in Medicine

Career 【 Display / hide

  • 2017.01
    -
    Present

    Department of Radiology, Keio University School of Medicine

  • 2016.01
    -
    2016.12

    Harvard Medical School, Brigham and Women’s Hospital , Radiology

  • 2010.04
    -
    2015.12

    Department of Radiology, Keio University School of Medicine

  • 2008.04
    -
    2010.03

    Department of Radiology, Nippon Koukan Hosptal

  • 2006.04
    -
    2008.03

    Department of Radiology, Keio University School of Medicine

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Academic Background 【 Display / hide

  • 1996.04
    -
    2002.03

    Keio University, School of Medicine

    Japan, University, Graduated

  • 2010.04
    -
    2013.03

    Keio University, 医学研究科

    Japan, Graduate School, Graduated, Doctoral course

Academic Degrees 【 Display / hide

  • 博士(医学), Keio University, Coursework, 2013.03

Licenses and Qualifications 【 Display / hide

  • Board certified diagnostic radiologist of the Japan Radiological Society, 2010.09

  • Specialist in the Japanese Board of Nuclear Medicine, 2015.07

  • Specialist in Positron Emission Tomography in the Japanese Board of Nuclear Medicine, 2013.08

  • Board Certified Fellow of the Japan Society of Ultrasonics in Medicine, 2018.10

  • 日本乳がん検診精度管理中央機構 検診マンモグラフィ読影認定医, 2008.10

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Research Areas 【 Display / hide

  • Radiation science

Research Keywords 【 Display / hide

  • Diagnostic Radiology

  • CT

  • Chest imaging

  • Cardiovascular imaging

  • Abdominal imaging

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Research Themes 【 Display / hide

  • Multidetector computed tomography, 

    2010.04
    -
    Present

  • Chest imaging, 

    2010.04
    -
    Present

  • Cardiovascular imaging, 

    2010.04
    -
    Present

  • Abdominal imaging, 

    2010.04
    -
    Present

  • Dual-energy CT, 

    2010.04
    -
    Present

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Books 【 Display / hide

  • ここから始める循環器疾患のCT・MRI

    Yoshitake YAMADA, 学研メディカル秀潤社, 2020.04

    Scope: fractional flow reserve computed from CT (FFRCT),  Contact page: p.102-103

  • 救急疾患の鑑別診断のポイント

    Yasuhiro Minami, Yoshitake Yamada, Hiroaki Sugiura, Masahiro Jinzaki, 学研メディカル秀潤社, 2019.09

    Scope: 肺野空洞性病変の鑑別,  Contact page: p.204-209

  • 救急疾患の鑑別診断のポイント

    Hiroaki Sugiura, Yasuhiro Minami, Yoshitake Yamada, Masahiro Jinzaki, 学研メディカル秀潤社, 2019.09

    Scope: 肺間質影の鑑別,  Contact page: p.210-215

  • Abdominal CT

    Yoshitake YAMADA, メディカルサイエンスインターナショナル, 2017.04

    Scope: XII. 腹部大動脈・下大静脈,  Contact page: p591-612

  • Abdominal CT

    Yoshitake YAMADA, メディカルサイエンスインターナショナル, 2017.04

    Scope: II.検査法,  Contact page: p37-44

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Papers 【 Display / hide

  • Difference in the airway luminal area between the standing and supine positions using upright and conventional computed tomography.

    Matsumoto S, Yamada Y, Yamada M, Chubachi S, Yokoyama Y, Matsuoka S, Tanabe A, Niijima Y, Murata M, Fukunaga K, Jinzaki M

    Clinical anatomy (New York, N.Y.) (Clinical Anatomy)  34 ( 8 ) 1150 - 1156 2021.07

    ISSN  0897-3806

     View Summary

    No clinical studies to date have compared the airway luminal area between supine and standing positions. Our aim was therefore to compare the airway luminal area between these two positions on computed tomography (CT) and to determine its correlation with forced expiratory volume in 1 s (FEV1). Thirty-two asymptomatic volunteers underwent both conventional (supine position) and upright (standing position) CT during deep inspiration breath-holding. Pulmonary function tests were conducted on the same day. We measured the airway luminal area on CT in each position. Paired t-tests and Pearson's correlation coefficients were used for statistical analysis. The average luminal areas of the trachea, right and left main bronchi, and average third-generation airway were greater in the standing than the supine position by 3.4%, 6.1%, 5.5%, and 5.2%, respectively. The correlation coefficients between airway luminal areas and FEV1 tended to be higher in the standing than the supine position; this correlation was highest for the average third-generation airway (r = 0.70, P < 0.0001). The airway luminal areas of the trachea, bilateral main bronchi, and average third-generation airway were greater in the standing than the supine position. The average third-generation airway area in the standing position had the highest correlation with FEV1.

  • Quantification of Adipose Tissue Around the Aortic Aneurysm - At the Dawn of a New Era.

    Okuda S, Yamada Y, Nakahara T, Jinzaki M

    Circulation journal : official journal of the Japanese Circulation Society (一般社団法人 日本循環器学会)   2021.06

    ISSN  1346-9843

  • A rare case of COVID-19 infection with laryngeal involvement.

    Asaoka M, Chubachi S, Yamada Y, Fukunaga K

    BMJ case reports (BMJ Case Reports)  14 ( 6 )  2021.06

  • Saphenous vein valve assessment utilizing upright CT to potentially improve graft assessment for bypass surgery.

    Nakahara T, Yamada M, Yokoyama Y, Yamada Y, Narita K, Imanishi N, Yamazaki M, Shimizu H, Narula J, Jinzaki M

    Scientific reports (Scientific Reports)  11 ( 1 ) 11602 2021.06

     View Summary

    Saphenous veins (SVs) are frequently employed as bypass grafts. The SV graft failure is predominantly seen at the valve site. Avoiding valves during vein harvest would help reduce graft failure. We endeavored to detect SV valves, tributaries, and vessel size employing upright computed tomography (CT) for the raw cadaver venous samples and in healthy volunteers. Five cadaver legs were scanned. Anatomical analysis showed 3.0 (IQR: 2.0–3.0) valves and 13.50 (IQR: 10.00–16.25) tributaries. The upright CT completely detected, compared to 2.0 (IQR: 1.5–2.5, p = 0.06) valves and 9.5 (IQR: 7.5–13.0, p = 0.13) tributaries by supine CT. From a total of 190 volunteers, 138 (men:75, women:63) were included. The number of valves from the SF junction to 35 cm were significantly higher in upright CT than in supine CT bilaterally [upright vs. supine, Right: 4 (IQR: 3–5) vs. 2 (IQR:1–2), p < 0.0001, Left: 4 (IQR: 3–5) vs. 2 (IQR: 1–2), p < 0.0001]. The number of tributaries and vessel areas per leg were also higher for upright compared with supine CT. Upright CT enables non-invasive detection of SV valves, tributaries, and vessel size. Although not tested here, it is expected that upright CT may potentially improve graft assessment for bypass surgery.

  • Anatomic and diagnostic considerations of facial mobility for understanding the effectiveness of facial massage: A pilot study.

    Okuda I, Yamada M, Yamada Y, Yokoyama Y, Kampan N, Akita K, Jinzaki M

    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (Skin Research and Technology)   2021.05

    ISSN  0909-752X

     View Summary

    Background: The effectiveness of facial massage is often explained by the resulting increases in the blood and lymphatic flow. However, it is difficult to explain the lifting effect on the cheeks. The aim of this study was to analyze facial mobility to further current understanding of the effectiveness of facial massage. Materials and Methods: Two kinds of analytical methods were designed using a cadaveric head as well as advanced computed tomography (CT). The cadaveric face was divided into three sections, and three different colors of ink were injected into each section. It was kept in a supine position for 24 hours, and the ink distribution was observed. Upright and supine CT examinations were performed on six healthy adult volunteers. The images of both were superimposed by a three-dimensional image analysis system, and changes in facial contours were analyzed. Results: The three colors of ink spread craniocaudally and were distributed differently from the gravitational vector. When both CT images were superimposed, two distinct lines were formed, which represented overlapping of the facial contours due to the two different CT images. These lines were found to correspond to the border of each color of the ink. Conclusion: Focusing on the mobility of the face, the soft tissue of the face had vertical mobility, and it was speculated that this mobility is involved in the effectiveness of facial massage. Our results could provide useful information for cosmetic treatment and contribute to the collection of scientific knowledge for anti-aging medicine.

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Reviews, Commentaries, etc. 【 Display / hide

  • A case of Ehlers-Danlos syndrome in which lung CT findings contributed to the diagnosis

    松本 晋作, 杉浦 弘明, 南 康大, 山田 祥岳, 渡辺 理沙, 福永 興壱, 陣崎 雅弘

    臨床放射線 (金原出版(株))  65 ( 1 ) 67 - 70 2020.01

    Other article, Joint Work,  ISSN  0009-9252

  • 【胸部の最新画像情報2020】肺野の画像所見が診断の契機となったEhlers-Danlos症候群の1例

    松本 晋作, 杉浦 弘明, 南 康大, 山田 祥岳, 渡辺 理沙, 福永 興壱, 陣崎 雅弘

    臨床放射線 (金原出版(株))  65 ( 1 ) 67 - 70 2020.01

    Other article, Joint Work,  ISSN  0009-9252

     View Summary

    症例は40歳代女性で、胸痛を主訴に近医を受診し、胸部単純X線で左気胸を指摘され当院へ紹介入院となった。胸部単純CTにて左気胸を認めた。両肺底部に複数の不整な嚢胞、両下葉に浸潤影、小葉中心性陰影および気管支拡張を認めた。なお、約1年前の肺炎時のCTでは嚢胞は認められなかった。胸腔ドレーンを留置するも気胸およびリークの改善を認めなかったため、胸腔鏡下左肺下葉嚢胞切除術を施行した。術後経過は良好で、術後約1週間で退院した。比較的若年者に繰り返す肺炎後に不整な嚢胞が散見され、難治性の気胸を発症したことから肺組織の脆弱性が示唆され、基礎疾患としてEhlers-Danlos症候群の可能性が疑われた。遺伝子検査ではCOL5A2遺伝子変異が陽性(ミスセンス変異)であり、古典型Ehlers-Danlos症候群と診断された。また、COL3A1遺伝子変異は陰性であったことから、血管型Ehlers-Danlos症候群は否定された。

  • DAT SPECTにおけるCSFマスク補正のSBR値の診断能への影響

    岩渕 雄, 中原 理紀, 亀山 征史, 松坂 陽至, 南 康大, 伊東 大介, 田渕 肇, 山田 祥岳, 陣崎 雅弘

    核医学 ((一社)日本核医学会)  56 ( Suppl. ) S175 - S175 2019.10

    Other article, Joint Work,  ISSN  0022-7854

  • 肺野異常陰影 3 肺間質影の鑑別

    杉浦弘明, 南康大, 山田祥岳, 陣崎雅弘

    画像診断 39 ( 11 ) A210‐215 2019.09

    Other article, Joint Work,  ISSN  0285-0524

  • 肺野異常陰影 2 肺野空洞性病変の鑑別

    南康大, 山田祥岳, 杉浦弘明, 陣崎雅弘

    画像診断 39 ( 11 ) A204‐A209 2019.09

    Other article, Joint Work,  ISSN  0285-0524

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Presentations 【 Display / hide

  • 【CT再入門-新技術で何がわかる?-】面検出器CTの活用 関節動態

    山田 稔, 山田 祥岳, 横山 陽一, 石井 和典, 名倉 武雄, 陣崎 雅弘

    画像診断, 2021.07, (株)学研メディカル秀潤社

  • 【CT再入門-新技術で何がわかる?-】Dual energy CTの活用 肺塞栓症

    田村 全, 山田 祥岳, 陣崎 雅弘

    画像診断, 2021.07, (株)学研メディカル秀潤社

  • 【CT再入門-新技術で何がわかる?-】立位CTの活用 脊椎すべり症

    山田 祥岳, 山田 稔, 横山 陽一, 名倉 武雄, 陣崎 雅弘

    画像診断, 2021.07, (株)学研メディカル秀潤社

  • 【CT再入門-新技術で何がわかる?-】立位CTの活用 骨盤臓器脱

    横山 陽一, 山田 祥岳, 山田 稔, 陣崎 雅弘

    画像診断, 2021.07, (株)学研メディカル秀潤社

  • 【CT再入門-新技術で何がわかる?-】立位CTの活用 鼠径ヘルニア

    山田 祥岳, 山田 稔, 横山 陽一, 陣崎 雅弘

    画像診断, 2021.07, (株)学研メディカル秀潤社

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Research Projects of Competitive Funds, etc. 【 Display / hide

  • Elucidation of human body function using upright CT ~Looking at the era of healthy longevity~

    2021.04
    -
    2024.03

    Keio University, 陣崎 雅弘, 秋田 大宇, 山田 稔, 山田 祥岳, 稲本 陽子, 秋田 恵一, 大竹 義人, 橋本 正弘, Grant-in-Aid for Scientific Research (B)

     View Summary

    これまでのCTは患者さんが仰向けに寝た臥位の静止撮影で、器質的疾患の定量・定性評価を担ってきた。それにより、生命予後の改善に貢献してきたが、動態である機能の定量・定性評価はほとんどできていなかった。現在は、超高齢化社会であり、生命予後と同時に健康長寿であることもとても重要である。
    我々は、立位や座位での4次元画像が可能なCT(立位/座位CT)を開発した。これを用いて、健康長寿に必須である嚥下機能・排尿機能・歩行機能を健常人および患者さんにおいて3次元・4次元的に解明し、機能障害の機序と重症度分類、機能改善の指標になる所見を明らかにしていきたい。

  • 力学解析向け個別人体相同モデル生成手法の開発

    2021.04
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    2024.03

    National Institute of Advanced Industrial Science and Technology, 遠藤 維, 多田 充徳, 鮎澤 光, 丸山 翼, 栗田 雄一, 名倉 武雄, 山田 祥岳, Grant-in-Aid for Scientific Research (B)

     View Summary

    本研究は、以下の3つの研究題目からなる。1) 個人別人体ボリュームモデル構築手法の開発:ボディスキャナから得られた個人の人体表皮形状から、CT画像テンプレートを使用して個人の人体ボリュームモデルを構築する。2) 個人別人体力学特性の同定手法の開発:1)より得られた個人の人体ボリュームモデルにもとづき、標準動作の計測データを入力として、個人の人体力学特性を同定する。3) 筋活性度に基づく力知覚量推定手法の開発:自身が発揮する接触力の大きさについて、どのように知覚しているかを、筋活性度を用いてモデル化する。

  • Diagnosis and treatment of lymphatic diseases using MR lymphangiography, photoacoustic imaging, and upright CT

    2021.04
    -
    2024.03

    Keio University, 曽我 茂義, 奥田 茂男, 井上 政則, 貴志 和生, 鈴木 悠史, 山田 稔, 山田 祥岳, Grant-in-Aid for Scientific Research (C)

     View Summary

    リンパ疾患はリンパ浮腫だけでも世界に1.7億人の患者がおり、癌患者の増加、手術の高度化などを背景に増加している。しかしリンパ系は殆どの疾患で診断も治療も十分に確立されていない。この主な原因はリンパ管の簡便な画像診断がなく、現在でも可視化が容易ではない事にある。従って、画像診断の進歩によるリンパ管の可視化と動態の解明が、これらの診療と研究を導くキーである。本研究では、先進的MRイメージングと独自のマルチモダリティアプローチにより、リンパ系の新規画像診断法の確立を目指す。リンパ管画像診断のレベルを押し上げ、より低侵襲で精密な治療へ展開する事で、リンパ管疾患に苦しむ多くの患者に福音をもたらしたい。

  • 逐次近似法再構成冠動脈CTが臨床転帰に与える影響に関する多施設無作為化比較試験

    2020.04
    -
    2024.03

    Tohoku University, 大田 英揮, 後岡 広太郎, 河野 淳, 西井 達矢, 北川 覚也, 城戸 輝仁, 山田 祥岳, 富澤 信夫, 真鍋 徳子, 尾田 済太郎, 立神 史稔, 堀井 陽祐, Grant-in-Aid for Scientific Research (C)

     View Summary

    近年,CT装置の発展に伴い,従来法の冠動脈CT撮影法と比較して,より低被曝で撮像できる,逐次近似法を用いた冠動脈CT検査が臨床に導入されてきた.しかし,新たなCT検査法が,従来の方法と比較して,患者の診療に同等の価値を与えているかどうか,明確なエビデンスが不足している.
    本研究では,従来の冠動脈CT検査法と新たな検査法を比較して,その後の患者の診療の流れ,および臨床的な転帰を比較検討する.本研究は国内多施設が参加する無作為化比較試験である.

  • Elucidation of undetermined pathological mechanism and quantification of the diseases that demonstrate more relevant symptoms in the standing position than in the supine position by using upright CT

    2020.04
    -
    2023.03

    Keio University, 山田 祥岳, 山田 稔, 橋本 正弘, 鈴木 達也, 成田 啓一, Grant-in-Aid for Scientific Research (C)

     View Summary

    現在の画像診断学において、CTは単純X線写真よりも基本的に診断能が高い。ただし、単純X線写真は立位で撮影可能であるが、CTは立位で撮影できない、という決定的な違いがあった。現在の通常のCTは臥位で撮影されるため、ヒトの日常生活の状態(立位/座位)を反映しておらず、立位で増悪する病態を3次元的に画像化できていなかった。そこで我々は、国内メーカーと共同で320列立位CTを開発し、慶應義塾大学病院に世界第1号機を導入した(座位撮影も可能)。本研究では、新たな診断機器である立位CTを用いて、立位で症状が増悪する疾患の病態を画像的に明らかにし、立位/座位での新たな画像診断法の確立と病態の定量化を目指す。

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Awards 【 Display / hide

  • Magna Cum Laude award at the 102nd Scientific Assembly and Annual Meeting of the Radiological Society of North America

    2016.11, Radiological Society of North America, Dynamic Chest Radiography Using Flat Panel Detector System: Technique and Applications

    Type of Award: Awards of International Conference, Council and Symposium.  Country: U.S.A.

  • Platinum Medal (the Best Presentation Award), the 79rd Annual Meeting of the Japan Radiological Society

    Yoshitake Yamada, Minoru Yamada, Yoichi Yokoyama, Akiko Tanabe, Shiho Matsuoka, Yuki Niijima, Mitsuru Murata, Koichi Fukunaga, Shotaro Chubachi, Masahiro Jinzaki, 2020.06, Japan Radiological Society, Comparison of Inspiratory and Expiratory Lung/Lobe Volumes Among Supine, Standing and Sitting Positions scanned with Conventional and 320-Detector-Row Upright CT

    Type of Award: Awards of National Conference, Council and Symposium.  Country: Japan

  • Certificate of Merit Award at the 103rd Scientific Assembly and Annual Meeting of the Radiological Society of North America

    2017.11, Radiological Society of North America, Four-dimensional (4D) Computed Tomography (CT) with Non-rigid Registration Between Adjacent Phases Before and After Transcatheter Aortic Valve Implantation (TAVI): One Step Forward Into the Future

    Type of Award: Awards of International Conference, Council and Symposium.  Country: U.S.A.

  • Silver Medal, the 80th Annual Meeting of the Japan Radiological Society

    Yoshitake Yamada, Shotaro Chubachi, Minoru Yamada, Yoichi Yokoyama, Akiko Tanabe, Shiho Matsuoka, Yuki Niijima, Mitsuru Murata, Koichi Fukunaga, Masahiro Jinzaki, 2021.04, Japan Radiological Society, Correlation between lung volumes on upright CT and measurements on pulmonary function test in COPD patients: comparison with supine CT

    Type of Award: Awards of National Conference, Council and Symposium.  Country: Japan

  • Bronze Medal, the 73rd Annual Meeting of the Japan Radiological Society

    2014.04, Japan Radiological Society, Renal cyst pseudoenhancement: Intra-individual comparison between virtual monochromatic spectral and conventional polychromatic 120-kVp images obtained during the same CT examination

    Type of Award: Awards of National Conference, Council and Symposium.  Country: Japan

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Other 【 Display / hide

  • JCS 2018 Guideline on Diagnosis of Chronic Coronary Heart Diseases: Cooperator

    2019年03月

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    JCS 2018 Guideline on Diagnosis of Chronic Coronary Heart Diseases: Cooperator

  • 2016年01月

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    The Uehara Memorial Foundation, Overseas research fellowships

 

Courses Taught 【 Display / hide

  • Diagnostic imaging of the chest

    2020, Full academic year, Major subject, Laboratory work/practical work/exercise, Within own faculty, 110people

  • Medical interview

    2020, Major subject, Laboratory work/practical work/exercise, 110people

  • Diagnostic imaging: Chest (Respiratory System)

    2020, Full academic year, Major subject, Laboratory work/practical work/exercise, Within own faculty, 110people

Courses Previously Taught 【 Display / hide

  • 肝・胆・膵の画像診断

    慶應義塾大学医学部, 2018

  • 骨盤腔の画像診断

    慶應義塾大学医学部, 2018

  • 肝・胆・膵の画像診断

    Keio University, 2017, Full academic year

  • 女性骨盤臓器の画像診断

    Keio University, 2015, Full academic year, Major subject, Laboratory work/practical work/exercise

  • 肝・胆・膵の画像診断

    Keio University, 2015, Full academic year, Major subject, Laboratory work/practical work/exercise

Educational Activities and Special Notes 【 Display / hide

  • The person in charge of Objective Structured Clinical Examination

    2019.04
    -
    Present

    , Special Affairs

 

Memberships in Academic Societies 【 Display / hide

  • Japan Radiological Society, 

    2006
    -
    Present
  • The Japan Society of Ultrasonics in Medicine, 

    2014
    -
    Present
  • The Japanese Society of Nuclear Medicine, 

    2013
    -
    Present
  • Radiological Society of North America, 

    2010
    -
    Present
  • The Japanese Circulation Society, 

    2014
    -
    Present

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