Yamada, Yoshitake

写真a

Affiliation

School of Medicine, Department of Radiology (Diagnostic Radiology) ( Shinanomachi )

Position

Associate Professor

External Links
Scopus Paper Info  
Paper Count: 224 Citation Count: 3639 h-index: 30

Click to view the Scopus page. The data was downloaded from Scopus API in February 22, 2026, via http://api.elsevier.com and http://www.scopus.com .

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Profile 【 Display / hide 】

  • Sep 2005-present: Board Certified Membership of the Japanese Society of Internal Medicine
    Sep 2010-present: Board Certified Diagnostic Radiologist of the Japan Radiological Society
    Aug 2013-present: Specialist in Positron Emission Tomography in the Japanese Board of Nuclear Medicine
    July 2015-present: Specialist in the Japanese Board of Nuclear Medicine
    October 2018-present: Board Certified Senior Fellow of the Japan Society of Ultrasonics in Medicine

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Career 【 Display / hide 】

  • 2017.01
    -
    Present

    Department of Radiology, Keio University School of Medicine

  • 2016.01
    -
    2016.12

    Harvard Medical School, Brigham and Women’s Hospital , Radiology

  • 2010.04
    -
    2015.12

    Department of Radiology, Keio University School of Medicine

  • 2008.04
    -
    2010.03

    Department of Radiology, Nippon Koukan Hosptal

  • 2006.04
    -
    2008.03

    Department of Radiology, Keio University School of Medicine

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Academic Background 【 Display / hide 】

  • 1996.04
    -
    2002.03

    Keio University, School of Medicine

    University, Graduated

  • 2010.04
    -
    2013.03

    Keio University, 医学研究科

    Graduate School, Graduated, Doctoral course

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Academic Degrees 【 Display / hide 】

  • 博士（医学）, Keio University, Coursework, 2013.03

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Licenses and Qualifications 【 Display / hide 】

  • Board certified diagnostic radiologist of the Japan Radiological Society, 2010.09

  • Specialist in the Japanese Board of Nuclear Medicine, 2015.07

  • Specialist in Positron Emission Tomography in the Japanese Board of Nuclear Medicine, 2013.08

  • Board Certified Fellow of the Japan Society of Ultrasonics in Medicine, 2018.10

  • 日本乳がん検診精度管理中央機構 検診マンモグラフィ読影認定医（指導医認定 AS）, 2008.10

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Research Areas 【 Display / hide 】

  • Life Science / Radiological sciences

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Research Keywords 【 Display / hide 】

  • Diagnostic Radiology

  • CT

  • Chest imaging

  • Cardiovascular imaging

  • Abdominal imaging

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Research Themes 【 Display / hide 】

  • Multidetector computed tomography, 

    2010.04
    -
    Present

  • Chest imaging, 

    2010.04
    -
    Present

  • Cardiovascular imaging, 

    2010.04
    -
    Present

  • Abdominal imaging, 

    2010.04
    -
    Present

  • Dual-energy CT, 

    2010.04
    -
    Present

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Books 【 Display / hide 】

  • ここから始める循環器疾患のCT・MRI

    Yoshitake YAMADA, 学研メディカル秀潤社, 2020.04

    Scope: fractional flow reserve computed from CT (FFRCT),  Contact page： p.102-103

  • 救急疾患の鑑別診断のポイント

    Yasuhiro Minami, Yoshitake Yamada, Hiroaki Sugiura, Masahiro Jinzaki, 学研メディカル秀潤社, 2019.09

    Scope: 肺野空洞性病変の鑑別,  Contact page： p.204-209

  • 救急疾患の鑑別診断のポイント

    Hiroaki Sugiura, Yasuhiro Minami, Yoshitake Yamada, Masahiro Jinzaki, 学研メディカル秀潤社, 2019.09

    Scope: 肺間質影の鑑別,  Contact page： p.210-215

  • Abdominal CT

    Yoshitake YAMADA, メディカルサイエンスインターナショナル, 2017.04

    Scope: XII. 腹部大動脈・下大静脈,  Contact page： p591-612

  • Abdominal CT

    Yoshitake YAMADA, メディカルサイエンスインターナショナル, 2017.04

    Scope: II.検査法,  Contact page： p37-44

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Papers 【 Display / hide 】

  • Free-breathing Three-dimensional MR Cholangiopancreatography Using Centric k-space Encoding Improved Gallbladder Visualization: A Prospective Study

    Junya Tsuzaki, Taiki Nozaki, Daiki Ito, Tetsushi Habe, Sayaka Miyazaki, Manabu Arai, Manabu Hase, Hiroki Sakata, Ryo Tsukada, Yoshitake Yamada, Masahiro Jinzaki

    Magnetic Resonance in Medical Sciences  2026.02

    Accepted,  ISSN  1347-3182

  • Three-dimensional analysis of shoulder hand-behind-back motion in patients with frozen shoulder

    Takafumi Niwa, Noboru Matsumura, Yuki Yoshida, Yoichi Yokoyama, Minoru Yamada, Yoshitake Yamada, Takeo Nagura, Masaya Nakamura, Masahiro Jinzaki

    Journal of Shoulder and Elbow Surgery  2026.02

    Accepted,  ISSN  1058-2746

  • Comparison of supine and upright postures in carbon ion radiotherapy for pancreatic cancer: An in silico planning study.

    Nomura Y, Inaniwa T, Isozaki T, Kurosaki H, Shinoto M, Yamada Y, Yamada M, Yokoyama Y, Mizuno H, Yonai S, Iwata Y, Takeda A, Ishikawa H, Jinzaki M

    Medical physics 53 ( 2 ) e70325 2026.02

    ISSN  0094-2405

    　View Summary

    Background: Conducting carbon ion radiotherapy (CIRT) in upright posture has several technical advantages over that in conventional supine posture for pancreatic cancer treatment. However, few studies have investigated effects of upright positioning on anatomy and CIRT dose distributions. Purpose: This study compared anatomy and dose distributions in CIRT for pancreatic cancer between supine and upright postures. Methods: Fourteen pairs of computed tomography (CT) images obtained from asymptomatic volunteers in these postures were analyzed. Clinical target volume (CTV), organs-at-risk (OARs), and gastrointestinal gas contours were delineated within a planning volume for each CT image, and a CIRT dose distribution was calculated. The anatomical differences between these postures were evaluated by comparing volumes and 3D rendered images of the contours, while the dosimetric differences were assessed with 12 dosimetric metrics. Moreover, a proximal overlap volume of the OARs and possible change in water-equivalent path length due to gastrointestinal gas were calculated for all coplanar beam angles to compare ranges of applicable beam angles and potential range uncertainty between these postures. Results: The bowel contour volumes in the upright posture were more than 46% smaller than those in the supine posture because the bowel was shifted. The upright posture provided a smaller dose to the bowel and higher dose coverage to the CTV than the supine posture. The possible water-equivalent path length changes due to the stomach and duodenum gas decreased at most beam angles in the upright posture. Conclusions: The upright CIRT had several anatomical and dosimetric advantages for pancreatic cancer treatment over conventional supine CIRT. This technique will be useful in applying the patient-specific beam angle arrangement and precise dose delivery with reduced range uncertainty.

  • Three-dimensional in vivo kinematics of the subtalar joint during weight-bearing standing on coronal-wedge surfaces using upright computed tomography.

    Naomichi Ogihara, Hiroyuki Seki, Asahi Sujino, Akimasa Ito, Yuka Matsumoto, Gen Suwa, Takeo Nagura, Yoichi Yokoyama, Minoru Yamada, Yoshitake Yamada, Masahiro Jinzaki

    Gait & posture 123   110021 - 110021 2026.01

    Accepted,  ISSN  0966-6362

    　View Summary

    BACKGROUND: The human subtalar joint is crucial for bipedal posture and locomotion, providing stability, adaptability, and force dissipation. While its kinematics have been studied, most research has been under non-weight-bearing conditions, leaving its function under physiological loading unclear. RESEARCH QUESTION: What is the three-dimensional kinematics of the human subtalar joint during weight-bearing postures, as quantified by the helical axis? METHODS: This study analyzed three-dimensional in vivo subtalar joint kinematics during weight-bearing using upright CT. Fifteen healthy elderly adults (11 females, 4 males; mean age: 64.9 ± 5.0 years) underwent CT scans in neutral, inverted, and everted postures using 10° coronal wedges. Kinematics were quantified via helical axis representation relative to two talar coordinate systems: the foot longitudinal axis and the talus principal axis. RESULTS: The helical axis ran obliquely from anterior-medial-dorsal to posterior-lateral-plantar, with inclination and deviation angles of 22.4° ± 9.6° and 35.2° ± 5.6° in the former system, and 36.5° ± 10.7° and 12.0° ± 7.1° in the latter. Rotation along the axis was 9.9° ± 3.8°, with minimal translation (0.5 ± 0.5 mm). SIGNIFICANCE: These findings suggest subtalar joint movement is more constrained under weight-bearing conditions than in non-weight-bearing studies. This study underscores the importance of weight-bearing analyses for clinical applications and understanding human foot adaptations for bipedalism.

  • Quantitative airway evaluation using supine and upright computed tomography in patients with non-cystic fibrosis bronchiectasis and nontuberculous mycobacterial pulmonary disease.

    Masanori Kaji, Takanori Asakura, Yoshitake Yamada, Hiromu Tanaka, Ho Namkoong, Shotaro Chubachi, Minoru Yamada, Takuya Ozawa, Yoichi Yokoyama, Shin Iizuka, Keiichi Narita, Genta Nagao, Ryoichi Kato, Naoki Fukunaga, Shunsuke Nakamura, Shuhei Azekawa, Sayaka Miyazaki, Kensuke Nakagawara, Hirofumi Kamata, Richard C Boucher, Koichi Fukunaga, Naoki Hasegawa, Masahiro Jinzaki

    European journal of radiology 195   112626 - 112626 2025.12

    Accepted,  ISSN  0720-048X

    　View Summary

    INTRODUCTION: Bronchiectasis, closely associated with nontuberculous mycobacterial pulmonary disease (NTM-PD), exhibits unevenly distributed lesions, yet their spatial features remain unclear. We hypothesized that upright CT, which may better depict distal airways due to gravity-induced lung expansion, might more accurately reflect disease severity and its relationship with pulmonary function tests (PFTs). METHODS: In this prospective study, twenty patients underwent low-dose inspiratory and expiratory CT scans in standing and supine positions. Airways were segmented with Vincent® software and classified as bronchiectatic or non-bronchiectatic. Generation-specific quantitative CT (QCT) parameters, including inspiratory airway total area (ITA), inspiratory airway lumen area (ILA), wall thickness, and wall area percentage (WA%), were measured and correlated with PFTs. RESULTS: Bronchiectatic lesions were primarily identified in the 8th-10th generation airways (anatomically the 7th-9th generations), the transition from distal bronchi to proximal bronchioles. Standing CT detected more distal airways than supine CT. Mixed-effect models revealed significantly larger ITA and higher WA% in bronchiectatic airways (8th-10th generations) on standing CT. In non-bronchiectatic airways (trachea to 6th generation), ITA and ILA were significantly larger in the standing position, except for the main bronchus ITA. ITA, ILA, and WA% were moderate to strongly correlated with %FVC, %FEV1, and FEF25-75%, reflecting airway obstruction, with stronger correlations in the standing position. ITA in bronchiectatic airways was moderately negatively correlated with diffusing capacity of the lungs for carbon monoxide, indicating potential alveolar disease. CONCLUSION: Upright CT offers useful structural biomarkers associated with airflow limitation and possible alveolar impairment in bronchiectasis with NTM-PD. REGISTRATION: University Hospital Medical Information Network (UMIN 000026587). URL: https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000030456.

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Reviews, Commentaries, etc. 【 Display / hide 】

  • 肺非結核性抗酸菌(NTM)症の立位/臥位胸部CTを用いた肺体積の定量評価

    加治 正憲, 朝倉 崇徳, 田中 拓, 飯塚 紳, 小澤 拓矢, 福永 直輝, 長尾 元太, 阿瀬川 周平, 中川原 賢亮, 南宮 湖, 鎌田 浩史, 山田 祥岳, 長谷川 直樹

    結核 ((一社)日本結核・非結核性抗酸菌症学会)  100 ( 3 ) 163 - 163 2025.05

    ISSN  0022-9776

  • 立位CT・床反力計同時計測による下肢荷重線の検討 内外側wedgeの影響

    関 広幸, 荻原 直道, 伊藤 滉真, 筋野 朝陽, 山田 祥岳, 横山 陽一, 中村 雅也, 陣崎 雅弘, 名倉 武雄

    日本整形外科学会雑誌 ((公社)日本整形外科学会)  99 ( 3 ) S676 - S676 2025.03

    ISSN  0021-5325

  • 肺非結核性抗酸菌(NTM)症の立位/臥位胸部CTを用いた肺体積の定量評価

    加治 正憲, 朝倉 崇徳, 田中 拓, 南宮 湖, 中鉢 正太郎, 飯塚 紳, 小澤 拓矢, 福永 直輝, 長尾 元太, 阿瀬川 周平, 中川原 賢亮, 鎌田 浩史, 山田 祥岳, 福永 興壱, 長谷川 直樹

    日本呼吸器学会誌 ((一社)日本呼吸器学会)  14 ( 増刊 ) 281 - 281 2025.03

    ISSN  2186-5876

  • 姿勢変化における脊柱可動域の性差 立位CTを用いた分析

    水越 諒, 八木 満, 山田 祥岳, 渡辺 航太, 名倉 武雄, 中村 雅也, 陣崎 雅弘

    日本整形外科学会雑誌 ((公社)日本整形外科学会)  98 ( 8 ) S1954 - S1954 2024.09

    ISSN  0021-5325

  • 慢性腎臓病患者における腎洞脂肪量と腎血行動態の関連の検証

    金子 賢司, 満野 竜之介, 児島 大輝, 畔上 達彦, 小杉 将太郎, 中村 俊文, 橋口 明典, 山田 祥岳, 陣崎 雅弘, 山口 慎太郎, 伊藤 裕, 吉野 純, 林 香

    日本腎臓学会誌 ((一社)日本腎臓学会)  66 ( 4 ) 586 - 586 2024.06

    ISSN  0385-2385

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Presentations 【 Display / hide 】

  • 体位変化が脳循環に与える影響　座位CTを用いた解析

    水谷 克洋, 山田 祥岳, 山田 稔, 横山 陽一, 小杉 健三, 吉田 啓佑, 高橋 里史, 秋山 武紀, 戸田 正博, 陣崎 雅弘

    日本脳神経血管内治療学会学術集会抄録集, 

    2025.11
    , 

    (一社)日本脳神経血管内治療学会

  • 原発性アルドステロン症患者における脂肪分布の特徴とその臨床的意義の検討

    満野 竜ノ介, 中村 俊文, 中村 健吾, 金子 賢司, 児島 大輝, 水谷 洋佑, 山田 祥岳, 畔上 達彦, 神田 武志, 木内 謙一郎, 吉野 純, 林 香

    肥満研究, 

    2025.10
    , 

    (一社)日本肥満学会

  • 異なる年齢層における脊椎回転の特徴とその影響　立位CTを用いた分析

    水越 諒, 八木 満, 山田 祥岳, 横山 陽一, 山田 稔, 渡辺 航太, 中村 雅也, 名倉 武雄, 陣崎 雅弘

    日本整形外科学会雑誌, 

    2025.09
    , 

    (公社)日本整形外科学会

  • 新手法である立位CTにおける、冠動脈カルシウムスコア(Agatson Score)の妥当性

    山川 裕之, 山田 祥岳, 家田 真樹, 陣崎 雅弘, 高石 官均

    日本人間ドック・予防医療学会誌, 

    2025.08
    , 

    (公社)日本人間ドック・予防医療学会

  • 骨盤臓器脱における術前後における立位CTの有用性　新たな画像診断技術の可能性

    木須 伊織, 横山 陽一, 山田 稔, 山田 祥岳, 岩田 卓, 山上 亘, 陣崎 雅弘

    日本女性骨盤底医学会プログラム・抄録集, 

    2025.07
    , 

    日本女性骨盤底医学会

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Research Projects of Competitive Funds, etc. 【 Display / hide 】

  • Analysis of the Human Body Under Gravity Using Upright CT and Its Application to Future Medicine

    2025.04
    -
    2029.03

    Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), No Setting

    　View Summary

    これまでの医療の主な診断対象は生命寿命を規定する器質的疾患であったが、今後、機能性疾患を対象とした健康寿命の延伸の為の医療が重要になる。立位CTの導入により、姿勢・骨盤底の緩み・筋肉量など身体的フレイルの評価、立位で増悪する腰痛の診断・膝関節異常の早期発見・嚥下機能や排尿機能の評価など機能性障害の病態解明や早期診断が可能になる。また、放射線治療を座位の状態で行えればコストや設置面積を大幅に縮小できる。今回は、立位・座位で評価可能な人体の構造・機能を解明し、それに基づき、①身体的フレイルの評価、②機能性障害の病態解明と早期診断、③座位放射線治療の実現、の新たな診断・治療への有効性を明らかにする。

  • 超高齢社会における健康寿命延伸を目指した新たなCT診断学の構築

    2025.02
    -
    2026.03

    Japan Radiological Society, Research grant from Japan Radiological Society supported by Bayer, Principal investigator

  • Elucidation of age-related changes and pathology and establishment of a method for early detection of diseases using upright CT: Aiming at extending healthy life expectancy

    2023.04
    -
    2026.03

    Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), No Setting

    　View Summary

    現在の通常のCTは臥位で撮影するため、ヒトの日常生活の状態(立位/座位) を反映しておらず、立位/座位での様々な病態を3次元的に画像化できていなかった。そこで我々は産学共同で320列立位CTを開発し、当施設に世界第１号機を導入した。これまでの初期検討により、立位と臥位で解剖学的構造や各種病態はかなり異なる事が分かった。この初期結果をふまえ、本研究では、新たな診断機器である立位CTを用いて、立位荷重下でより顕著となる加齢性変化や各種病態を画像的に解明しつつ、立位/座位での新たな疾患早期検出法の確立を目指す。そして立位CTによる早期診断により、超高齢社会における健康寿命の更なる延伸、生活の質の向上を目指す。

  • Construction of CT Diagnostics in the Near Future: Aiming at Extending Healthy Life Span in the Super-aging Society

    2022.09
    -
    Present

    Takeda Science Foundation, 医学系研究助成 臨床, Principal investigator

  • Diagnosis and treatment of lymphatic diseases using MR lymphangiography, photoacoustic imaging, and upright CT

    2021.04
    -
    2024.03

    Keio University, Grants-in-Aid for Scientific Research, Soga Shigeyoshi, Grant-in-Aid for Scientific Research (C), No Setting

    　View Summary

    This study aimed to establish advanced lymphatic imaging techniques using MR lymphangiography (MRL), photoacoustic imaging (PAI), and upright CT. We developed a novel MRL-based severity classification of lymphedema and published it in an international journal. This system characterizes patterns of dermal backflow and lymphatic visualization based on anatomical region and clinical stage, showing significant correlations with disease severity and duration. It enables a more detailed assessment of individual pathology and supports optimal treatment planning. We also established an improved robust MRL protocol with reduced artifacts and applied MR thoracic ductography to manage refractory lymphatic leakage. Furthermore, comparative analyses of MRL and PAI clarified their complementary roles. Quantitative evaluation of fat tissue changes related to lymphedema was also conducted. These efforts contributed to the standardization of diagnostic approaches in lymphatic disease management.

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Intellectual Property Rights, etc. 【 Display / hide 】

  • X線コンピュータ断層撮影装置

    Date applied： 特願2021-183419  2021.11 

    Date announced： 特開2023-070936  2023.05 

    Patent, Joint

  • 被検体の透明化方法および透明化された被検体の製造方法

    Date applied： 特願2020-082566  2020.05 

    Date announced： 特開2021-177146  2021.11 

    Date issued： 特許第7411223号 

    Date registered： 2023.12

    Patent, Joint

  • 外反母趾の予防方法

    Date applied： 特願2019-091025  2019.05 

    Date announced： 特開2020-185121  2020.11 

    Patent

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Awards 【 Display / hide 】

  • Magna Cum Laude award at the 102nd Scientific Assembly and Annual Meeting of the Radiological Society of North America

    2016.11, Radiological Society of North America, Dynamic Chest Radiography Using Flat Panel Detector System: Technique and Applications

    Type of Award： Award from international society, conference, symposium, etc.,  Country： United States

  • Platinum Medal (the Best Presentation Award) at the 79rd Annual Meeting of the Japan Radiological Society

    Yoshitake Yamada, Minoru Yamada, Yoichi Yokoyama, Akiko Tanabe, Shiho Matsuoka, Yuki Niijima, Mitsuru Murata, Koichi Fukunaga, Shotaro Chubachi, Masahiro Jinzaki, 2020.06, Japan Radiological Society, Comparison of Inspiratory and Expiratory Lung/Lobe Volumes Among Supine, Standing and Sitting Positions scanned with Conventional and 320-Detector-Row Upright CT

    Type of Award： Award from Japanese society, conference, symposium, etc.

  • Certificate of Merit Award at the 103rd Scientific Assembly and Annual Meeting of the Radiological Society of North America

    2017.11, Radiological Society of North America, Four-dimensional (4D) Computed Tomography (CT) with Non-rigid Registration Between Adjacent Phases Before and After Transcatheter Aortic Valve Implantation (TAVI): One Step Forward Into the Future

    Type of Award： Award from international society, conference, symposium, etc.,  Country： United States

  • Achievement Award, Japanese Society of Medical Imaging Technology

    Masahiro Jinzaki, Yoshitake Yamada, Minoru Yamada, Yoichi Yokoyama, Takeo Nagura, Naomichi Ogihara, Yasutaka Shindo, Makoto Nakano, 2022.07, Japanese Society of Medical Imaging Technology, Development of Whole-Body Upright Computed Tomography

    Type of Award： Award from Japanese society, conference, symposium, etc.

  • Silver Medal, the 80th Annual Meeting of the Japan Radiological Society

    Yoshitake Yamada, Shotaro Chubachi, Minoru Yamada, Yoichi Yokoyama, Akiko Tanabe, Shiho Matsuoka, Yuki Niijima, Mitsuru Murata, Koichi Fukunaga, Masahiro Jinzaki, 2021.04, Japan Radiological Society, Correlation between lung volumes on upright CT and measurements on pulmonary function test in COPD patients: comparison with supine CT

    Type of Award： Award from Japanese society, conference, symposium, etc.

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Other 【 Display / hide 】

  • JCS 2018 Guideline on Diagnosis of Chronic Coronary Heart Diseases: Cooperator

    2019年03月

    　View Details

    JCS 2018 Guideline on Diagnosis of Chronic Coronary Heart Diseases: Cooperator

  • 2016年01月

    　View Details

    The Uehara Memorial Foundation, Overseas research fellowships

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Courses Taught 【 Display / hide 】

  • LECTURE SERIES, RADIOLOGY

    2025

  • CLINICAL CLERKSHIP IN RADIOLOGY

    2025

  • LECTURE SERIES, RADIOLOGY

    2024

  • CLINICAL CLERKSHIP IN RADIOLOGY

    2024

  • INTRODUCTION TO CLINICAL CLERKSHIPS

    2023

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Courses Previously Taught 【 Display / hide 】

  • 肝・胆・膵の画像診断

    慶應義塾大学医学部

    2018.04
    -
    2019.03

  • 骨盤腔の画像診断

    慶應義塾大学医学部

    2018.04
    -
    2019.03

  • 肝・胆・膵の画像診断

    Keio University

    2017.04
    -
    2018.03
    , 

    Full academic year

  • 女性骨盤臓器の画像診断

    Keio University

    2015.04
    -
    2016.03
    , 

    Full academic year, Laboratory work/practical work/exercise

  • 肝・胆・膵の画像診断

    Keio University

    2015.04
    -
    2016.03
    , 

    Full academic year, Laboratory work/practical work/exercise

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Educational Activities and Special Notes 【 Display / hide 】

  • The person in charge of Objective Structured Clinical Examination

    2019.04
    -
    Present

    , Special Affairs

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Memberships in Academic Societies 【 Display / hide 】

  • Japan Radiological Society, 

    2006
    -
    Present

  • The Japan Society of Ultrasonics in Medicine, 

    2014
    -
    Present

  • The Japanese Society of Nuclear Medicine, 

    2013
    -
    Present

  • Radiological Society of North America, 

    2010
    -
    Present

  • The Japanese Circulation Society, 

    2014
    -
    Present

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