研究者詳細 - 陣崎　雅弘

論文 - 陣崎　雅弘

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画像に基づく病期診断-腎癌-

陣崎雅弘，谷本伸弘，栗林幸夫

画像診断 22 （ 9 ） 974-983 2002年08月

研究論文（学術雑誌）, 共著

末梢動脈の閉塞性病変におけるMultidetector CTを用いた3次元画像の有用性

松本一宏，陣崎雅弘，佐藤浩三，奥田茂男，中塚誠之，谷本伸弘，橋本統，栗林幸夫

脈管学 42 （ 8 ） 505-510 2002年08月

研究論文（学術雑誌）, 共著

Routine MR imaging protocol with breath-hold fast scans

Tanimoto Akihiro, Yuasa Yuji, Jinzaki Masahiro, Nakatsuka Seishi, Takeda Toshiaki, Kurata Tadayoshi, Shinmoto Hiroshi, Kuribayashi Sachio

Radiation Medicine - Medical Imaging and Radiation Oncology 20 （ 4 ） 169 - 179 2002年07月

研究論文（学術雑誌）, 共著, ISSN 0288-2043

Purpose: To qualitatively and quantitatively evaluate the diagnostic efficacy of the breathhold magnetic resonance (MR) imaging sequences in widespread clinical use for detection and characterization of focal hepatic lesions. Materials and Methods: Fifty patients with 143 lesions [57 hepatocellular carcinomas (HCC), 10 borderline lesions, 18 metastatic tumors, 21 hemangiomas, and 37 cysts] underwent single-shot fast spin echo (SSFSE), fast spin echo (FSE), and gadolinium-enhanced dynamic fast spoiled gradient-recalled acquisition in steady state (FSPGR) breath-hold MR imaging of the liver. Alternative free receiver operating characteristic (AFROC) analysis was performed to independently and prospectively assess each sequence. Results: For solid lesions, dynamic FSPGR allowed the most sensitive lesion detection and produced the highest lesion conspicuity and lesion-liver contrast-to-noise ratio (CNR). For non-solid benign lesions, SSFSE and FSE produced better results than dynamic FSPGR. SSFSE allowed the most sensitive detection and produced the best lesion conspicuity and lesion-liver CNR. Conclusion: SSFSE and dynamic FSPGR comprise the optimal imaging protocol for breathhold MR assessment of focal hepatic lesions. This combination of sequences allows acquisition of critical diagnostic information about both inherent T2 and T1 lesion contrast and lesion vascularity.

非侵襲的冠動脈イメージング

陣崎雅弘

Views Radiology 4 （ 2 ） 6-14 2002年05月

研究論文（学術雑誌）, 単著

末梢動脈の閉塞性動脈硬化症におけるMDCTを用いた三次元画像および自動血管計測の有用性－8列MDCTの臨床経験を含めて

松本一宏，陣崎雅弘，佐藤浩三，栗林幸夫，新屋昌恵，新井清忠

Innervision 17 （ 4 ） 24-25 2002年04月

研究論文（学術雑誌）, 共著

Outcome of hepatic nodules less than 10 mm in size detected by ultrasonography in patients with chronic liver disease

Tanami Yutaka, Ogawa Kenji, Tanami Yoshiko, Okada Masahiro, Matsumoto Kazuhiro, Fujiwara Hirokazu, Jinzaki Masahiro, Ohkuma Kiyoshi, Kuribayashi Sachio

Nippon Acta Radiologica 62 （ 1 ） 17 - 22 2002年01月

研究論文（学術雑誌）, 共著, ISSN 0048-0428

The number of hepatic nodules detected by ultrasonography in patients with chronic liver disease has increased. Although it potentially is important to understand the outcome of small solitary hepatic nodules, they have not been fully investigated. In this study, we evaluated retrospectively the outcome of 35 solitary hepatic nodules smaller than 10 mm in 35 patients with chronic liver disease. The follow-up period ranged from 24 to 94 months, and, during follow-up, 8 of 35 nodules (23%) increased in size, 17 nodules (49 %) showed no change, and 10 nodules (29%) disappeared. It took less than 12 months for 5 nodules to increase in size, and less than 24 months for 3 nodules. There was no significant difference between the ultrasonographic findings (echogenicity and size) of the nodules and their outcome. We conclude that follow-up observation of at least 24 months is essential to evaluate the outcome of solitary hepatic nodules.

Superparamagnetic iron oxide-mediated hepatic signal intensity change in patients with and without cirrhosis

Tanimoto Akihiro, Yuasa Yuji, Shinmoto Hiroshi, Jinzaki Masahiro, Imai Yutaka, Okuda Shigeo, Kuribayashi Sachio

Radiology 222 （ 3 ） 661 - 666 2002年

研究論文（学術雑誌）, 共著, ISSN 0033-8419

PURPOSE: To analyze superparamagnetic iron oxide (SPIO)-mediated hepatic signal intensity change in cirrhotic and noncirrhotic liver and to investigate the relationship between pulse sequence effects in SPIO-enhanced magnetic resonance (MR) imaging for hepatic cirrhosis. MATERIALS AND METHODS: Twelve patients with and 12 patients without cirrhosis underwent T2-weighted fast spin-echo, T2*-weighted gradient-echo (GRE), and T1-weighted GRE MR imaging before and twice (early and late phase) after SPIO administration. To assess the effect of SPIO, postcontrast relative signal-to-noise ratio (SNR) changes were statistically analyzed with repeated measurements analysis of variance for each pulse sequence. RESULTS: No interaction was shown between groups and data time points for any pulse sequence. There was no significant difference in mean hepatic relative SNR change on T2-weighted fast spin-echo images between the cirrhotic group and noncirrhotic group (-38.6% and -40.7%, early phase; -42.2% and -49.6%, late phase, respectively). For GRE images, statistically significant differences in mean hepatic relative SNR change were found between the cirrhotic group and noncirrhotic group (-14.2% and -44.5%, early phase; -28.5% and -56.4%, late phase on T2*-weighted GRE images (P < .001); 31.8% and 12.9%, early phase; 23.8% and 2.2%, late phase on T1-weighted GRE images (P < .05), respectively. CONCLUSION: Decreased overall phagocytic activity in cirrhotic liver is more likely due to Kupffer cell dysfunction than to Kupffer cell depletion, since magnetic susceptibility effects on T2*-weighted GRE images depend on intracellular SPIO cluster size. © RSNA, 2002.

冠動脈のマルチスライスCT

陣崎雅弘

Circulation Insights （ 12 ） 14 -16 2001年12月

研究論文（学術雑誌）, 単著

X線CT（マルチスライスCT）における三次元画像診断

佐藤浩三，陣崎雅弘，栗林幸夫，久保敦司，白神伸之，小林成司

RADIOISOTOPES 50 （ 12月） 618-629 2001年12月

研究論文（学術雑誌）, 共著

MDCTの症例報告

佐藤浩三，陣崎雅弘，栗林幸夫

日本放射線技術学会雑誌 57 （ 7 ） 28-29 2001年07月

研究論文（学術雑誌）, 共著

Visualization of tumor vessels in renal tumors. Comparison between power Doppler ultrasonography and angiography

Tamura Yoshiko, Jinzaki Masahiro, Ohkuma Kiyoshi, Hashimoto Subaru, Tanimoto Akihiro, Hiramatsu Kyoichi

Acta Radiologica 42 （ 2 ） 239-243 2001年03月

研究論文（学術雑誌）, 共著

MR imaging-guided prostate biopsy with surgical navigation software

Hata N., Jinzaki M., Kacher D., Cormak R., Gering D., Nabavi A., Silverman S. G., D'Amico A. V., Kikinis R., Jolesz F. A., Tempany C. M C

Radiology 220 （ 1 ） 263 - 268 2001年

研究論文（学術雑誌）, 共著, ISSN 0033-8419

Ｘ線ＣＴ（マルチスライスＣＴ）による三次元画像診断

佐藤浩三, 陣崎雅弘, 栗林幸夫, 久保敦司, 白神伸之, 小林成司

ＲＡＤＩＯＩＳＯＴＯＰＥＳ（公益社団法人日本アイソトープ協会） 50 （ 12 ） 618 - 629 2001年

ISSN 0033-8303

腎血管筋脂肪腫における画像診断の進歩と限界

大家基嗣, 陣崎雅弘, 村井勝

日本泌尿器科学会雑誌（一般社団法人日本泌尿器科学会） 92 （ 2 ） 87 2001年

ISSN 0021-5287

Transperineal magnetic resonance image guided prostate biopsy

D'Amico A. V., Tempany C. M., Cormack R., Hata N., Jinzaki M., Tuncali K., Weinstein M., Richie J. P.

Journal of Urology 164 （ 2 ） 385 - 387 2000年08月

研究論文（学術雑誌）, 共著, ISSN 0022-5347

Purpose: We report the findings of a transperineal magnetic resonance image (MRI) guided biopsy of the prostate in a man with increasing prostate specific antigen who was not a candidate for a transrectal ultrasound guided biopsy. Materials and Methods: Using an open configuration 0.5 Tesla MRI scanner and pelvic coil, a random sextant sample was obtained under real time MRI guidance from the peripheral zone of the prostate gland as well as a single core from each MRI defined lesion. The patient had previously undergone proctocolectomy for ulcerative colitis and, therefore, was not a candidate for transrectal ultrasound guided biopsy. Prior attempts to make the diagnosis of prostate cancer using a transurethral approach were unsuccessful. Results: The random sextant samples contained benign prostatic hyperplasia, whereas Gleason grade 3 + 3 = 6 adenocarcinoma was confirmed in 15% and 25% of the 2 cores obtained from the MRI targeted specimens of 2 defined lesions. The procedure was well tolerated by the patient. Conclusions: Transperineal MRI guided biopsy is a new technique that may be useful in detecting prostate cancer in men with increasing prostate specific antigen who are not candidates for transrectal ultrasound guided biopsy.

内視鏡手技とっておきのコツ　胃静脈瘤の治療　Shunt Occluded Sclerotherapy (SOS)

北川雄光，大森泰，陣崎雅弘，橋本統，熊井浩一郎，日比紀文，岩男泰，小澤壯治，安藤暢敏，北島政樹

消化器内視鏡 12 （ 6 ） 780-781 2000年06月

研究論文（学術雑誌）, 共著

Double-phase helical CT of small renal parenchymal neoplasms: correlation with pathologic findings and tumor angiogenesis

Jinzaki Masahiro, Tanimoto Akihiro, Mukai Makio, Ikeda Eiji, Kobayashi Seiji, Yuasa Yuji, Narimatsu Yoshiaki, Murai Masaru

Journal of Computer Assisted Tomography 24 （ 6 ） 835 - 842 2000年

研究論文（学術雑誌）, 共著, ISSN 0363-8715

Purpose: To correlate the enhancement pattern of double-phase helical computed tomography (CT) of small renal parenchymal neoplasms with pathologic findings and tumor angiogenesis, and evaluate whether the enhancement pattern would be useful in differentiating the histomorphologic types of small renal parenchymal neoplasms. Materials and Methods: Double-phase helical CT (5 mm slice) of the cortico-medullary phase (CMP) and late nephrographic phase (NP) was performed in 40 surgically resected renal neoplasms <3.5 cm. The patterns of CT attenuation value and homogeneity were correlated with the subtypes of neoplasms, microvessel density, and the existence of intratumoral necrosis or hemorrhage. Results: Clear cell renal cell carcinomas (RCC) (n = 29) showed a peak attenuation value in the CMP of >100 HU [Hounsfield units]. Chromophobe cell RCC (n = 2) showed a peak attenuation value in the CMP of <100 HU. Papillary RCC (n = 5) showed a gradual enhancement with the attenuation value in the CMP of <100 HU. However oncocytomas (n = 2) and metanephric adenomas (n = 2) also showed patterns similar to these subtypes of RCC. The degree of enhancement in the CMP correlated with microvessel density (r = 0.87). All tumors with an homogeneous enhancement pattern did not show necrosis or hemorrhage on histologic specimen. Conclusion: The enhancement pattern in double-phase helical CT was different among the subtypes of RCC, and correlated with microvessel density or the existence of intratumoral necrosis or hemorrhage. However it did not differentiate between RCC and other solid tumors.

Access to Document (DOI)

Breast cancer evaluated by contrast harmonic imaging using the pulse inversion method

Matsumoto K., Ohkuma K., Jinzaki M., Hiramatsu H., Kuribayashi S., Ikeda T.

Journal of Medical Ultrasonics 27 （ 11 ） 1427 - 1430 2000年

研究論文（学術雑誌）, 共著, ISSN 1344-1388

A 54-year-old woman was admitted to this institution for further examination and treatment of a mass in the fight breast. The mass was a palpable hard lump that measured approximately 2 cm in diameter. Breast cancer was strongly suspected, and ultrasound examination was performed. The conventional B-mode image showed a well-defined, hypoechoic mass with a lobulated margin in the right mammary gland; the color Doppler image showed a penetrating feeding vessel and intralesional vessels; and the contrast-enhanced color Doppler image showed intense signals from the intralesional vessels. The feeding and intralesional vessels were clearly shown in B-mode contrast harmonic imaging with pulse inversion. It was suggested that B-mode contrast harmonic imaging with pulse inversion is suitable for detection of tumor vessels in a small, superficial organ such as a mammary gland.

パワードプラ法の臨床応用

田波穣，大熊潔，陣崎雅弘，田村良子，布袋伸一，篠原真木子，平松京一

画像診断 19 （ 11 ） 1283-1292 1999年11月

研究論文（学術雑誌）, 共著

Small solid renal lesions: Usefulness of power doppler US

Jinzaki Masahiro, Ohkuma Kiyoshi, Tanimoto Akihiro, Mukai Makio, Hiramatsu Kyoichi, Murai Masaru, Hata Jun Ichi

Radiology 209 （ 2 ） 543 - 550 1998年11月

研究論文（学術雑誌）, 共著, ISSN 0033-8419

PURPOSE: To evaluate whether the vascular pattern at power Doppler ultrasonography (US) improves diagnostic accuracy in small solid renal lesions over that at gray-scale US. MATERIALS AND METHODS: Gray-scale and power Doppler US were performed prospectively in 64 small (1.5-3.0-cm- diameter) solid renal lesions (26 renal cell carcinomas [RCCs], 34 angiomyolipomas, two oncocytomas, two pseudotumors). At gray-scale US, echogenicity and homogeneity of the lesion, an anechoic rim, intratumoral cysts, shadowing, or a central scar were sought. At power Doppler US, the vascular distribution was divided into four patterns. RESULTS: Findings at gray-scale US included an anechoic rim or intratumoral cysts in 20 of 26 RCCs (77%) and the two oncocytomas. Shadowing was seen in seven of 34 angiomyolipomas (21%). Echogenicity, homogeneity, and a central scar were not pathognomonic. At power Doppler US, pattern 3 (peripheral) or 4 (mixed penetrating and peripheral) was seen in all RCCs, seven of 34 angiomyolipomas, and the two oncocytomas. Pattern 1 (intratumoral focal) or 2 (penetrating) was seen in 27 angiomyolipomas. Pattern 1 or 2 was characteristic of angiomyolipomas. The rate of correct diagnosis was significantly increased with combined US (78%) as compared to that with gray- scale (42%) or power Doppler (45%) US alone. CONCLUSION: The vascular distribution at power Doppler US could add important information to gray- scale US findings for differential diagnosis of small solid renal lesions.

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陣崎　雅弘

論文 - 陣崎　雅弘