KEIO RESEARCHERS INFORMATION SYSTEM

Academic Degrees 【 Display / hide 】

Academic Degrees 【 Display / hide 】

• 博士（医学）, Keio University, Dissertation, 2006.02

Licenses and Qualifications 【 Display / hide 】

Licenses and Qualifications 【 Display / hide 】

• 医師国家試験合格, 1990.06

• 日本泌尿器科学会専門医, 1995.04

• 日本泌尿器科学会指導医, 2000.04

• 日本小児泌尿器科学会認定医, 2007.04

• 日本臨床腎移植学会認定医, 2008.02

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Papers, etc., Registered in KOARA 【 Display / hide 】

Papers, etc., Registered in KOARA 【 Display / hide 】

• Development of novel therapeutic modality by integrated analysis of immune environment of renal cell carcinoma and remodeling after inhibition of angiogenesis

  Asanuma, Hiroshi

  科学研究費補助金研究成果報告書 2020

• Utility of liquid biopsy for metastatic renal cell carcinoma

  Asanuma, Hiroshi

  科学研究費補助金研究成果報告書 2019

• Elucidation of refractory mechanism to the molecular targeted therapy for renal cell carcinoma

  Asanuma, Hiroshi

  科学研究費補助金研究成果報告書 2017

• New treatment strategy with mesenchymal stem cells for obstructive uropathy

  Asanuma, Hiroshi

  科学研究費補助金研究成果報告書 2016

• Resistance to mTOR inhibitor in metastatic dialysis-related renal cell carcinoma

  Asanuma, Hiroshi

  科学研究費補助金研究成果報告書 2014

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Research Projects of Competitive Funds, etc. 【 Display / hide 】

Research Projects of Competitive Funds, etc. 【 Display / hide 】

• 膀胱尿管逆流に対するカラードプラ法超音波検査を用いた新たな非侵襲的診断法の確立

  2018.04

  -

  2021.03

  MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Principal investigator

• New treatment strategy with mesenchymal stem cells for obstructive uropathy

  2014.04

  -

  2017.03

  MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Principal investigator

  　View Summary

  The effect of mesenchymal stem cells (MSCs) therapy on chronic obstruction-induced renal fibrosis has not previously been evaluated. Rats with partial ureteral obstruction underwent injection of fluorescent-labeled human and rat MSCs. From 3 days to 4 weeks later, the kidneys were harvested and the renal cortex analyzed for evidence of stem cell infiltration, epithelial-mesenchymal transition (EMT), renal fibrosis, and cytokine and growth factor activity.
  MSCs were detected in the interstitium of the kidney more than 4 weeks post-obstruction. MSCs provided protection against obstruction-induced EMT and chronic renal fibrosis. While the mechanism of MSCs-induced renal protection during obstruction remains unclear, exogenous MSCs reduced obstruction-induced TNF-alpha levels, but did not alter TGF-beta1, VEGF, IL-10, FGF, HGF expression.

Awards 【 Display / hide 】

Awards 【 Display / hide 】

• Best Poster Award (the 108th American Urological Association Annual Meeting)

  2013.05

• Best Poster Award (the 107th American Urological Association Annual Meeting)

  2012.05

• 学会会長賞（第18回日本小児泌尿器科学会総会）

  2009.10

• 学会会長賞（第11回日本小児泌尿器科学会総会）

  2002.07

• IPTA Award（the 1st Congress of the International Pediatric Transplant Association）

  2000.08

Courses Taught 【 Display / hide 】

Courses Taught 【 Display / hide 】

• LECTURE SERIES, UROLOGY

  2024

• CLINICAL CLERKSHIP IN UROLOGY

  2024

• LECTURE SERIES, UROLOGY

  2023

• CLINICAL CLERKSHIP IN UROLOGY

  2023

• LECTURE SERIES, UROLOGY

  2022

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