Asanuma, Hiroshi

写真a

Affiliation

School of Medicine, Department of Urology (Shinanomachi)

Position

Associate Professor

Academic Degrees 【 Display / hide

  • 博士(医学), Keio University, Dissertation, 2006.02

Licenses and Qualifications 【 Display / hide

  • 医師国家試験合格, 1990.06

  • 日本泌尿器科学会専門医, 1995.04

  • 日本泌尿器科学会指導医, 2000.04

  • 日本小児泌尿器科学会認定医, 2007.04

  • 日本臨床腎移植学会認定医, 2008.02

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Papers, etc., Registered in KOARA 【 Display / hide

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Research Projects of Competitive Funds, etc. 【 Display / hide

  • 膀胱尿管逆流に対するカラードプラ法超音波検査を用いた新たな非侵襲的診断法の確立

    2018.04
    -
    2021.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 浅沼 宏, Grant-in-Aid for Scientific Research (C), Principal Investigator

  • New treatment strategy with mesenchymal stem cells for obstructive uropathy

    2014.04
    -
    2017.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 浅沼 宏, Grant-in-Aid for Scientific Research (C), Principal Investigator

     View Summary

    The effect of mesenchymal stem cells (MSCs) therapy on chronic obstruction-induced renal fibrosis has not previously been evaluated. Rats with partial ureteral obstruction underwent injection of fluorescent-labeled human and rat MSCs. From 3 days to 4 weeks later, the kidneys were harvested and the renal cortex analyzed for evidence of stem cell infiltration, epithelial-mesenchymal transition (EMT), renal fibrosis, and cytokine and growth factor activity.
    MSCs were detected in the interstitium of the kidney more than 4 weeks post-obstruction. MSCs provided protection against obstruction-induced EMT and chronic renal fibrosis. While the mechanism of MSCs-induced renal protection during obstruction remains unclear, exogenous MSCs reduced obstruction-induced TNF-alpha levels, but did not alter TGF-beta1, VEGF, IL-10, FGF, HGF expression.

Awards 【 Display / hide

  • Best Poster Award (the 108th American Urological Association Annual Meeting)

    2013.05

  • Best Poster Award (the 107th American Urological Association Annual Meeting)

    2012.05

  • 学会会長賞(第18回日本小児泌尿器科学会総会)

    2009.10

  • 学会会長賞(第11回日本小児泌尿器科学会総会)

    2002.07

  • IPTA Award(the 1st Congress of the International Pediatric Transplant Association)

    2000.08

 

Courses Taught 【 Display / hide

  • LECTURE SERIES, UROLOGY

    2020

  • CLINICAL CLERKSHIP IN UROLOGY

    2020

  • CLINICAL CLERKSHIP IN UROLOGY

    2019

  • LECTURE SERIES, UROLOGY

    2019