飛彈 麻里子 (ヒダ マリコ)

Hida, Mariko

写真a

所属(所属キャンパス)

医学部 小児科学教室 (信濃町)

職名

准教授

 

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  • Tubular dysfunction in extremely low birth weight survivors

    Matsumura K., Matsuzaki Y., Hida M., Ikeda K., Awazu M.

    Clinical and Experimental Nephrology (Clinical and Experimental Nephrology)  23 ( 3 ) 395 - 401 2019年03月

    ISSN  13421751

     概要を見る

    © 2018, Japanese Society of Nephrology. Background: Extremely low birth weight (ELBW) survivors may develop glomerulosclerosis due to low nephron number, whereas their tubular function remains unknown except for hypercalciuria and phosphaturia. Methods: Fifty-three subjects (30 boys and 23 girls, aged 7 months-19 years, median 36 months) were studied retrospectively. The median gestational age and birth weight were 26 weeks (range 22–32) and 745 g (range 316–999), respectively. Urine calcium-to-creatinine ratio (Ca/Cr), N-acetyl-β-d-glucosaminidase-to-creatinine ratio (NAG/Cr), β2 microglobulin-to-creatinine ratio (β2m/Cr), uric acid-to-creatinine ratio (UA/Cr), glucose-to-creatinine ratio (glu/Cr), and microalbumin-to-creatinine ratio (malb/Cr) were examined. We also assessed the association between urine parameters and current age, gestational age, birth weight, and predictors of renal injury. Follow-up data were analyzed in 43 subjects 4–6 years later. Results: Ninety percent of subjects had at least one tubular dysfunction. Frequency of elevated values was NAG/Cr 77.5%, UA/Cr 54.1%, β2m/Cr 38.2%, malb/Cr 30.4%, Ca/Cr 21.5%, and glu/Cr 20.5%. There were significant negative correlations between the current age and Ca/Cr, NAG/Cr, glu/Cr, and UA/Cr, suggesting tubular function maturation. Urine β2M/Cr and glu/Cr were negatively correlated with the gestational age. There were significant associations between elevated glu/Cr and asphyxia or neonatal acute kidney injury, and elevated NAG/Cr and indomethacin use, although these were not confirmed by multivariate analysis. At follow-up, the frequency of elevated NAG/Cr, glu/Cr, UA/Cr, and malb/Cr was reduced but that of elevated Ca/Cr, IgG/Cr, and β2m/Cr remained similar or increased. Conclusion: Tubular dysfunction is common in ELBW survivors. Some abnormalities resolved with age while some remained persistent or even increased.

  • 培養尿細管細胞周期的伸展刺激によるp38MAPキナーゼの活性化

    藤田尚代,長田道夫,金本勝義,福田恵一,大森さゆ,飛弾麻里子,粟津緑

    日本小児腎臓病学会雑誌 16 ( 1 ) 29-33 2003年01月

    研究論文(学術雑誌), 共著

  • 培養尿管芽細胞周期的伸展刺激によるp38 MAPキナーゼの活性化

    藤田尚代,長田道夫,金本勝義,福田恵一,大森さゆ,飛彈麻里子,粟津緑

    小児腎臓病学会誌 16   29-34 2003年

    研究論文(学術雑誌), 共著

  • MAP kinase in renal development

    Awazu Midori, Omori Sayu, Hida Mariko

    Nephrology dialysis transplantation 17 ( [Suppl9] ) 5-7 2002年09月

    研究論文(学術雑誌), 共著

  • The herbal medicine Sairei to inhibits proliferation of rat mesangial cells

    Awazu Midori, Fujita Hisayo, Omori Sayu, Hida Mariko

    Nephron 92 ( 3 ) 652-659 2002年07月

    研究論文(学術雑誌), 共著

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研究発表 【 表示 / 非表示

  • 妊娠前から出産後まで継続的に関わりをもった思春期妊娠の1症例

    関口進一郎,飛彈麻里子,渡辺久子,高橋孝雄

    第507回日本小児科学会東京都地方会講話会, 

    2002年12月

    口頭発表(一般)

  • Cyclic stretch stimulates proliferation and Pax2 expression via p38 mitogen-activated protein kinase in a ureteric bud cell line

    Fujita Hisayo, Nagata Michio, Kanemoto Katsuyoshi, Fukuda Keiichi, Omori Sayu, Hida Mariko, Awazu Midori

    Annual Meeting, 

    2002年11月

    ポスター発表

  • Gene expression profiling in rat model of tubulointerstitial fibrosis

    Awazu Midori, Fujita Hisayo, Hida Mariko, Omori Sayu

    Annual Meeting, 

    2002年11月

    ポスター発表

  • Expression and role of RhoA/ROCK in renal development

    Hida Mariko, Fujita Hisayo, Omori Sayu, Awazu Midori

    Annual Meeting, 

    2002年11月

    ポスター発表

  • Expression of mitogen-activated protein kinases in obstructed uropathy in fetal lambs

    Omori Sayu, Kitagawa Hiroaki, Koike Junki, Fujita Hisayo, Hida Mariko, Pringle Kevin C, Awazu Midori

    American Society of Nephrology, 

    2002年11月

    ポスター発表

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競争的研究費の研究課題 【 表示 / 非表示

  • 早産によるネフロン形成早期終止におけるHIFの役割解明と治療の試み

    2015年04月
    -
    2018年03月

    文部科学省・日本学術振興会, 科学研究費助成事業, 飛彈 麻里子, 基盤研究(C), 補助金,  研究代表者

 

担当授業科目 【 表示 / 非表示

  • 助産実践

    2024年度

  • 助産ケア学Ⅱ(ハイリスクマタニティケア)

    2024年度

  • 小児科学講義

    2024年度

  • クリニカルエンジニアリングと医療安全管理

    2024年度

  • 小児科学講義

    2023年度

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