Hida, Mariko

写真a

Affiliation

School of Medicine, Department of Pediatrics (Shinanomachi)

Position

Associate Professor

 

Papers 【 Display / hide

  • Tubular dysfunction in extremely low birth weight survivors

    Matsumura K., Matsuzaki Y., Hida M., Ikeda K., Awazu M.

    Clinical and Experimental Nephrology (Clinical and Experimental Nephrology)  23 ( 3 ) 395 - 401 2019.03

    ISSN  13421751

     View Summary

    © 2018, Japanese Society of Nephrology. Background: Extremely low birth weight (ELBW) survivors may develop glomerulosclerosis due to low nephron number, whereas their tubular function remains unknown except for hypercalciuria and phosphaturia. Methods: Fifty-three subjects (30 boys and 23 girls, aged 7 months-19 years, median 36 months) were studied retrospectively. The median gestational age and birth weight were 26 weeks (range 22–32) and 745 g (range 316–999), respectively. Urine calcium-to-creatinine ratio (Ca/Cr), N-acetyl-β-d-glucosaminidase-to-creatinine ratio (NAG/Cr), β2 microglobulin-to-creatinine ratio (β2m/Cr), uric acid-to-creatinine ratio (UA/Cr), glucose-to-creatinine ratio (glu/Cr), and microalbumin-to-creatinine ratio (malb/Cr) were examined. We also assessed the association between urine parameters and current age, gestational age, birth weight, and predictors of renal injury. Follow-up data were analyzed in 43 subjects 4–6 years later. Results: Ninety percent of subjects had at least one tubular dysfunction. Frequency of elevated values was NAG/Cr 77.5%, UA/Cr 54.1%, β2m/Cr 38.2%, malb/Cr 30.4%, Ca/Cr 21.5%, and glu/Cr 20.5%. There were significant negative correlations between the current age and Ca/Cr, NAG/Cr, glu/Cr, and UA/Cr, suggesting tubular function maturation. Urine β2M/Cr and glu/Cr were negatively correlated with the gestational age. There were significant associations between elevated glu/Cr and asphyxia or neonatal acute kidney injury, and elevated NAG/Cr and indomethacin use, although these were not confirmed by multivariate analysis. At follow-up, the frequency of elevated NAG/Cr, glu/Cr, UA/Cr, and malb/Cr was reduced but that of elevated Ca/Cr, IgG/Cr, and β2m/Cr remained similar or increased. Conclusion: Tubular dysfunction is common in ELBW survivors. Some abnormalities resolved with age while some remained persistent or even increased.

  • 培養尿細管細胞周期的伸展刺激によるp38MAPキナーゼの活性化

    Fujita Naoyo, Osada Michio, Kanamoto Katsuyoshi, Fukuda Keiichi, Oomori Sayu, Hida Mariko, Awazu Midori

    日本小児腎臓病学会雑誌 16 ( 1 ) 29-33 2003.01

    Research paper (scientific journal), Joint Work

  • 培養尿管芽細胞周期的伸展刺激によるp38 MAPキナーゼの活性化

    Fujita Hisayo, Nagata Michio, Kanemoto Katsuyoshi, Fukuda Keiichi, Oomori Sayu, Hida Mariko, Awazu Midori

    小児腎臓病学会誌 16   29-34 2003

    Research paper (scientific journal), Joint Work

  • MAP kinase in renal development

    Awazu Midori, Omori Sayu, Hida Mariko

    Nephrology dialysis transplantation 17 ( [Suppl9] ) 5-7 2002.09

    Research paper (scientific journal), Joint Work

  • The herbal medicine Sairei to inhibits proliferation of rat mesangial cells

    Awazu Midori, Fujita Hisayo, Omori Sayu, Hida Mariko

    Nephron 92 ( 3 ) 652-659 2002.07

    Research paper (scientific journal), Joint Work

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Papers, etc., Registered in KOARA 【 Display / hide

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Presentations 【 Display / hide

  • 妊娠前から出産後まで継続的に関わりをもった思春期妊娠の1症例

    Sekiguchi Shinichirou, Hida Mariko, Watanabe Hisako, Takahashi Takao

    第507回日本小児科学会東京都地方会講話会, 

    2002.12

    Oral presentation (general)

  • Cyclic stretch stimulates proliferation and Pax2 expression via p38 mitogen-activated protein kinase in a ureteric bud cell line

    Fujita Hisayo, Nagata Michio, Kanemoto Katsuyoshi, Fukuda Keiichi, Omori Sayu, Hida Mariko, Awazu Midori

    Annual Meeting, 

    2002.11

    Poster presentation

  • Gene expression profiling in rat model of tubulointerstitial fibrosis

    Awazu Midori, Fujita Hisayo, Hida Mariko, Omori Sayu

    Annual Meeting, 

    2002.11

    Poster presentation

  • Expression and role of RhoA/ROCK in renal development

    Hida Mariko, Fujita Hisayo, Omori Sayu, Awazu Midori

    Annual Meeting, 

    2002.11

    Poster presentation

  • Expression of mitogen-activated protein kinases in obstructed uropathy in fetal lambs

    Omori Sayu, Kitagawa Hiroaki, Koike Junki, Fujita Hisayo, Hida Mariko, Pringle Kevin C, Awazu Midori

    American Society of Nephrology, 

    2002.11

    Poster presentation

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Research Projects of Competitive Funds, etc. 【 Display / hide

  • Analysis of the role of HIF in early termination of nephrogenesis due to prematurity and development of treatment.

    2015.04
    -
    2018.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Principal investigator

 

Courses Taught 【 Display / hide

  • NURSE-MIDWIFERY PRACTICUM

    2022

  • MIDWIFERY CARE2(HIGH RISK MATERNITY CARE)

    2022

  • LECTURE SERIES, PEDIATRICS

    2022

  • CLINICAL ENGINEERING AND SAFETY CONTROL IN HEALTH CARE

    2022

  • NURSE-MIDWIFERY PRACTICUM

    2021

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