Arimitsu, Takeshi

写真a

Affiliation

School of Medicine, Department of Pediatrics （Shinanomachi）

Position

Assistant Professor/Senior Assistant Professor
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Career 【 Display / hide 】

  • 2002.05
    -
    Present

    慶應義塾大学　医学部　小児科学教室, 研修医

  • 2004.05
    -
    Present

    慶應義塾大学　医学部　小児科学教室, 専修医

  • 2010.04
    -
    Present

    慶應義塾大学　医学部　小児科学教室, 助教

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Academic Background 【 Display / hide 】

  • 2002.03

    Keio University, School of Medicine

    University, Graduated

  • 2006.04
    -
    2010.03

    Keio University, 医学研究科

    Graduate School, Completed, Doctoral course

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Academic Degrees 【 Display / hide 】

  • 博士(医学), Keio University, Coursework, 2010.03

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Licenses and Qualifications 【 Display / hide 】

  • 周産期（新生児）専門医

  • 小児科専門医

  • 医師免許証

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Research Areas 【 Display / hide 】

  • Humanities & Social Sciences / Childhood and nursery/pre-school education

  • Life Science / Neuroscience-general

  • Life Science / Basic brain sciences

  • Life Science / Embryonic medicine and pediatrics

  • Humanities & Social Sciences / Cognitive science

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Research Keywords 【 Display / hide 】

  • 新生児

  • 早産児

  • 母子愛着

  • 発達

  • 近赤外分光法

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Books 【 Display / hide 】

  • 改訂2版　標準ディベロップメンタルケア

    ARIMITSU Takeshi, 株式会社 メディカ出版, 2018.09

    Scope: NICUの環境デザイン

  • 日本小児科学会新生児委員会編　新生児のプライマリ・ケア

    ARIMITSU Takeshi, 診断と治療社, 2016.05

    Scope: 発熱，体温低下

  • CARLS Series of Advanced Study of Logic and Sensibility

    ARIMITSU Takeshi, Keio University Press, 2011

    Scope: 137-148

  • CARLS Series of Advanced Study of Logic and Sensibility

    ARIMITSU Takeshi, Keio University Press, 2010

    Scope: 165-175

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Papers 【 Display / hide 】

  • Symbolic time series analysis of fNIRS signals in brain development assessment.

    Liang Z, Minagawa Y, Yang HC, Tian H, Cheng L, Arimitsu T, Takahashi T, Tong Y.

    J Neural Eng. [Epub ahead of print 2018.09

    Research paper (scientific journal), Joint Work, Accepted

  • The cerebral hemodynamic response to phonetic changes of speech in preterm and term infants

    Arimitsu Takeshi, Minagawa Yasuyo, Yagihashi Tatsuhiko, O. Uchida Mariko, Matsuzaki Atsuko, Ikeda Kazushige, Takahashi Takao

    NeuroImage: Clinical 19   599 - 606 2018.05

    Research paper (scientific journal), Joint Work, Accepted,  ISSN  2213-1582

    　View Summary

    <p>Higher brain dysfunction, such as language delay, is a major concern among preterm infants. Cerebral substrates of cognitive development in preterm infants remain elusive, partly because of limited methods. The present study focuses on hemodynamic response patterns for brain function by using near-infrared spectroscopy. Specifically, the study investigates gestational differences in the hemodynamic response pattern evoked in response to phonetic changes of speech and cerebral hemispheric specialization of the auditory area in preterm infants (n = 60) and term infants (n = 20). Eighty neonates born between 26 and 41 weeks of gestational age (GA) were tested from 33 to 41 weeks of postmenstrual age (PMA). We analyzed the hemodynamic response pattern to phonemic and prosodic contrasts for multiple channels on temporal regions and the laterality index of the auditory area. Preterm infants younger than 39 weeks of PMA showed significantly atypical hemodynamic patterns, with an inverted response shape. Partial correlation analysis of the typicality score of hemodynamic response revealed a significant positive correlation with PMA. The laterality index of preterm infants from 39 weeks of PMA demonstrated a tendency rightward dominance for prosodic changes similar to term infants. We provide new evidence that alterations in hemodynamic regulation and the functional system for phonemic and prosodic processing in preterm infants catch up by their projected due dates.</p>

  • Effect of mother’s voice on neonatal respiratory activity and EEG delta amplitude

    Mariko Uchida-Ota, Takeshi Arimitsu, Kiyomi Yatabe, Kazushige Ikeda, Takao Takahashi, and Yasuyo Minagawa

    Developmental Psychobiology 60   140 - 149 2018.03

    Research paper (scientific journal), Joint Work, Accepted

  • 供血児に頭蓋内出血および腎機能障害を発症し新生児死亡に至ったacute peripartum TTTSの1例

    ARIMITSU Takeshi

    日本周産期・新生児医学会雑誌 （日本周産期・新生児医学会)  53 （ 1 ） 244 - 248 2017.05

    Research paper (scientific journal), Joint Work, Accepted

  • Assessment of developing speech perception in preterm infants using near-infrared spectroscopy

    Arimitsu Takeshi, Minagawa Yasuyo, Takahashi Takao, Ikeda Kazushige

    NeoReviews 16 （ 8 ） e481 - e489 2015.08

    ISSN  1526-9906

    　View Summary

    <p>Despite improved survival rates of infants, higher brain dysfunction in surviving infants remains a considerable problem. Most infants with higher brain dysfunctions are born preterm. Magnetic resonance imaging (MRI) is a useful tool to detect structural brain damage and provides important information to evaluate the neurologic sequelae of such preterm infants. AlthoughMRI can reveal detailed brain structure, it is not the best option to assess brain function in preterm infants because of various restrictions. To overcome this difficulty, a new imaging technique, called functional near infrared spectroscopy (fNIRS), can be used to evaluate brain function in preterm infants. fNIRS is a suitable method to examine infants because, unlikeMRI, it is not necessary to restrict movement and it is silent. In this review, we focus on language function, an important higher human brain function and one of the most prominent difficulties among grown preterm infants. We describe the development of speech perception in infants from preterm to age 1 year. First, we discuss the development of the brain hemodynamic response to speech stimulation in full-term infants, imaged using fNIRS. Second, we discuss the functional specialization in full-term infants for speech processing in the cerebral cortex as revealed by fNIRS. Third, we discuss potential interpretations of developmental changes in brain activation during speech perception in preterm infants. We present data that reveal the development of speech processing in full-term and preterm infants. We conclude that fNIRS can aid in the anticipation of language delay in preterm infants and may facilitate early intervention and treatment of such dysfunctions.</p>

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Papers, etc., Registered in KOARA 【 Display / hide 】

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Reviews, Commentaries, etc. 【 Display / hide 】

  • 2018108461 【光環境と睡眠・概日リズム】 胎児・新生児・乳児の睡眠発達と光環境

    ARIMITSU Takeshi

    睡眠医療 (株式会社ライフ・サイエンス)  11 ( 4 ) 507 - 515 2017.12

    Article, review, commentary, editorial, etc. (scientific journal)

  • 【母と子の診断羅針盤】 【新生児編】体温　低体温

    ARIMITSU Takeshi

    周産期医学 (東京医学社)  47   477 - 482 2017.12

    Article, review, commentary, editorial, etc. (scientific journal), Single Work

  • 【小児科エコー活用術】 体幹・表在　脳

    ARIMITSU Takeshi

    小児科診療 (診断と治療社)  80 ( 11 ) 1401 - 1410 2017.11

    Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media), Single Work

  • 【子どもの眠り】 疾患と睡眠障害　胎児・新生児・乳児の睡眠発達プロセス

    ARIMITSU Takeshi

    小児内科 (東京医学社)  49 ( 8 ) 1180 - 1187 2017.08

    Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media), Joint Work

  • 【周産期におけるファミリーセンタードケア】 施設　NICU環境

    ARIMITSU Takeshi

    周産期医学 (東京医学社)  47 ( 1 ) 49 - 53 2017.01

    Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)

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Presentations 【 Display / hide 】

  • 早産児の音声言語処理の脳機能発達

    ARIMITSU Takeshi

    第21回日本光脳機能イメージング学会 (星陵会館（東京都千代田区）) , 

    2018.07
    , 

    Oral presentation (invited, special)

  • 在胎週数によって生後日齢が睡眠時の脳領域の結合に及ぼす影響は異なる

    ARIMITSU Takeshi

    日本周産期・新生児医学会 (東京国際フォーラム（東京都千代田区）) , 

    2018.07
    , 

    Oral presentation (general)

  • 早産児の脳を育むNICUの音環境デザイン

    ARIMITSU Takeshi

    神奈川こども　第4回新生児発達支援セミナー (神奈川県立こども医療センター（神奈川県横浜市）) , 

    2018.05
    , 

    Oral presentation (invited, special)

  • 近赤外分光法を用いた新生児の脳機能発達の検討

    ARIMITSU Takeshi

    第一回新生児基礎TR研究会, 

    2018.02
    , 

    Oral presentation (general)

  • 音環境で赤ちゃんを育む

    ARIMITSU Takeshi

    第20回新生児呼吸療法モニタリングフォーラム (大町市文化会館（長野県大町市）) , 

    2018.02
    , 

    Oral presentation (invited, special)

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Research Projects of Competitive Funds, etc. 【 Display / hide 】

  • 親と環境が早産児の高次脳機能発達を促す機序の近赤外分光法と行動指標による研究

    2019.04
    -
    2023.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Principal investigator

  • 近赤外分光法と視線計測を用いた脳室周囲白質軟化症の高次脳機能障害の解明

    2015.04
    -
    Present

    Grant-in-Aid for Scientific Research, Principal investigator

  • 非侵襲的脳機能測定法を用いた脳室周囲白質軟化症における認知・発達メカニズムの解明

    2013.04
    -
    2015.03

    Grant-in-Aid for Scientific Research, Principal investigator

  • The regulation of voltage-gated ion channels expressed on neuronal dendrites in hypoxic-ischemic encephalopathy

    2009.04
    -
    2013.03

    Grant-in-Aid for Scientific Research, ARIMITSU, Takeshi, Principal investigator

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Courses Taught 【 Display / hide 】

  • LECTURE SERIES, PEDIATRICS

    2024

  • LECTURE SERIES, PEDIATRICS

    2023

  • LECTURE SERIES, PEDIATRICS

    2022

  • LECTURE SERIES, PEDIATRICS

    2021

  • LECTURE SERIES, PEDIATRICS

    2020

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Courses Previously Taught 【 Display / hide 】

  • 診断学実習

    慶應義塾大学医学部

    2018.04
    -
    2019.03

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Educational Activities and Special Notes 【 Display / hide 】

  • 第19回慶應義塾大学病院臨床研修指導医養成ワークショップ修了

    2014.06
    -
    Present

    , Special Affairs

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Memberships in Academic Societies 【 Display / hide 】

  • 公益社団法人　日本小児科学会

    　

  • 一般社団法人　日本新生児成育医学会

    　

  • 一般社団法人　日本周産期・新生児医学会

    　
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Committee Experiences 【 Display / hide 】

  • 2018.06
    -
    Present

    社会保険委員会委員, 日本新生児成育医学会

  • 2018.06
    -
    Present

    社会保険委員会幹事, 日本周産期・新生児医学会

  • 2016.06
    -
    2018.05

    社会保険委員会委員, 日本新生児成育医学会

  • 2016.06
    -
    2018.05

    社会保険委員会幹事, 日本周産期・新生児医学会

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