Arimitsu, Takeshi

写真a

Affiliation

School of Medicine, Department of Pediatrics (Shinanomachi)

Position

Assistant Professor/Senior Assistant Professor
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Career 【 Display / hide 】

  • 2002.05
    -
    Present

    慶應義塾大学　医学部　小児科学教室, 研修医

  • 2004.05
    -
    Present

    慶應義塾大学　医学部　小児科学教室, 専修医

  • 2010.04
    -
    Present

    慶應義塾大学　医学部　小児科学教室, 助教

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Academic Background 【 Display / hide 】

  • 2002.03

    Keio University, School of Medicine

    University, Graduated

  • 2006.04
    -
    2010.03

    Keio University, 医学研究科

    Graduate School, Completed, Doctoral course

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Academic Degrees 【 Display / hide 】

  • 博士(医学), Keio University, Coursework, 2010.03

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Licenses and Qualifications 【 Display / hide 】

  • 医師免許証

  • 周産期（新生児）専門医

  • 小児科専門医

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Research Areas 【 Display / hide 】

  • Humanities & Social Sciences / Childhood and nursery/pre-school education

  • Life Science / Neuroscience-general

  • Life Science / Basic brain sciences

  • Life Science / Embryonic medicine and pediatrics

  • Humanities & Social Sciences / Cognitive science

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Research Keywords 【 Display / hide 】

  • 新生児

  • 早産児

  • 母子愛着

  • 発達

  • 近赤外分光法

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Books 【 Display / hide 】

  • 改訂2版　標準ディベロップメンタルケア

    ARIMITSU Takeshi, 株式会社 メディカ出版, 2018.09

    Scope: NICUの環境デザイン

  • 日本小児科学会新生児委員会編　新生児のプライマリ・ケア

    ARIMITSU Takeshi, 診断と治療社, 2016.05

    Scope: 発熱，体温低下

  • CARLS Series of Advanced Study of Logic and Sensibility

    ARIMITSU Takeshi, Keio University Press, 2011

    Scope: 137-148

  • CARLS Series of Advanced Study of Logic and Sensibility

    ARIMITSU Takeshi, Keio University Press, 2010

    Scope: 165-175

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Papers 【 Display / hide 】

  • Discordant responses of bone formation and absorption markers in Japanese infants with vitamin D deficiency: a comprehensive matched case–control study

    Takahashi K., Ikeda K., Hara-Isono K., Nitta A., Nagano N., Arimitsu T.

    JBMR Plus 8 ( 5 )  2024.05

    　View Summary

    Vitamin D deficiency during infancy has been associated with increased bone turnover rate and bone mineral loss. However, few studies have examined bone turnover markers (BTMs) for both bone formation and resorption in infants with vitamin D deficiency. Here, we analyzed serum concentrations of 25OHD, intact parathormone (iPTH), and BTMs including total alkaline phosphatase (ALP), tartrate-resistant acid phosphatase isoform 5b (TRACP-5b), and serum type I collagen N-telopeptide (NTx) as well as basic clinical characteristics of 456 infants (626 samples) aged less than 12 mo born at Saitama City Hospital, Japan (latitude 35.9? North) between January 2021 and December 2022. One hundred sixteen infants (147 samples) were classified as having vitamin D deficiency (25OHD < 12.0 ng/mL), and 340 infants (479 samples) had sufficient vitamin D levels (25OHD = 12.0 ng/mL). In addition to 25OHD and ALP, both TRACP-5b and sNTx were measured in 331 infants (418 samples), while 90 infants (105 samples) had only TRACP-5b measured and 101 infants (103 samples) had only sNTx measured. Statistical comparison of 104 subjects each in the vitamin D deficiency and sufficiency groups after matching for the background characteristics revealed that the vitamin D deficiency group had significantly higher levels of ALP and iPTH compared with the sufficiency group (P = <.0001, .0012, respectively). However, no significant differences were found in TRACP-5b and NTx levels between the 2 groups (P = .19, .08, respectively). Our findings suggest discordant responses between bone formation and resorption markers in subclinical vitamin D deficiency during infancy.

  • Usefulness of a mobile airwayscope with a monitor in examination of the external genitalia of a 483 g female neonate

    Hiraizumi T., Sato T., Kobayashi H., Arimitsu T., Narumi S., Ishii T., Hasegawa T.

    Pediatrics International 66 ( 1 )  2024.01

    ISSN  13288067

  • Use of access port covers in transport incubators to improve thermoregulation during neonatal transport

    Fukuyama T., Arimitsu T.

    Scientific Reports 13 ( 1 )  2023.12

    　View Summary

    Hypothermia in newborns increases the risk of health complications and mortality. This study aimed to evaluate the effectiveness of using covers over snap-open access ports of a transport incubator to maintain the temperature within. The change in temperature inside the transport incubator was evaluated over a 15-min period at three ambient room temperatures (20 °C, 24 °C, and 28 °C), as well as for three snap-open access port conditions: closed, where ports are closed; open, where the two ports on one side are open; and covered, where the two ports on one side are open but a cover is used. The automatic temperature control of the incubator was set to 37 °C for all conditions. We repeated the same experiments three times. The temperature decrease inside the incubator was greater for the open than for the closed or covered access port conditions at all three 4 °C-increasing room temperatures (p < 0.05). The incubator temperature decreased as a function of decreasing room temperature only for the open condition, with no significant difference between the closed and covered conditions. Therefore, snap-open access port covers provide an option to maintain a constant temperature within the transport incubator, which may lower the risk of neonatal hypothermia.

  • Efficacy and safety of a telemedicine system in subjects with gestational diabetes mellitus (TELEGLAM): Study protocol for a randomized controlled trial

    Aoyama K., Nakajima Y., Meguro S., Sato Y., Goto R., Hida M., Arimitsu T., Kasuga Y., Tanaka M., Itoh H.

    Heliyon 9 ( 11 )  2023.11

    ISSN  24058440

    　View Summary

    Background: Strict glycemic control is important to prevent perinatal complications in patients with gestational diabetes mellitus (GDM). Patients often require insulin injection, and frequent hospital visits are necessary to adjust the dose of insulin, which is considered burdensome for pregnant patients. Telemedicine may reduce the burden of hospital visits, and previous studies have reported its safety in GDM patients. This study aimed to evaluate the efficacy of telemedicine in GDM patients, focusing on patient satisfaction and health economic indicators. Methods: This is a single-center, two-arm, randomized, open-label parallel-group study. Subjects will be selected from the patient population attending the Department of Endocrinology, Metabolism, and Nephrology, Keio University School of Medicine, Japan. Patients diagnosed with GDM by an oral glucose tolerance test (OGTT) by 29 weeks and 6 days of gestation who have undergone self-monitoring of blood glucose (SMBG) and insulin injection are eligible for inclusion. In the intervention group, telemedicine will be administered using the MeDaCa telemedicine system developed by the Medical Data Card, Inc., Tokyo, Japan. Subjects in the control group will be examined face-to-face every 2–3 weeks, as usual. We set health economic indicators and patient satisfaction as the primary endpoints, and will perform a cost-consequence analysis. Glycemic control indicators and perinatal outcomes will be evaluated as secondary endpoints. Conclusions: Eligible patients are currently being recruited. Recruitment will be completed when the expected number of patients are enrolled.

  • Consensus core outcome rating for the Japanese neonatal pain guidelines

    Arimitsu T., Ozawa M., Gaughwin K.

    Frontiers in Pediatrics 11 2023.07

    　View Summary

    Introduction: The Japanese Neonatal Pain Guidelines Committee, led by the Japan Academy of Neonatal Nursing, uses the Grading of Recommendations, Assessment, Development, and Evaluation Working Group method to evaluate the quality of evidence and the strength of treatment recommendations. Ratings on the importance of outcomes related to neonatal pain have not been reported. This study aimed to reach a consensus on the importance of outcomes through a guideline panel composed of doctors, nurses, a nurse practitioner, a physical therapist, and families to ensure consistency in systematic reviews of neonatal pain and future revisions to the guidelines. Methods: A total of 26 professionals, including 21 medical personnel from clinical settings and academia and 5 parents from five family associations, participated in 3-stage eDelphi rounds. Results: The literature review and discussion identified 75 outcomes that were included in round one. The participants proposed three additional outcomes: 78 outcomes were scored in rounds two and three. Round three scores showed different stakeholder groups in terms of priority outcomes. Seventeen outcomes were included in the final core outcome and were considered critical for decision-making. Conclusion: Core outcomes of the development of neonatal pain guidelines in Japan were identified. The assessment process of importance from this study highlights the difference in the perspectives of medical providers and parents on neonatal pain, thus, involving parents in the assessment and as the spokesperson for the infant admitted to the neonatal intensive care unit is important for a more inclusive evaluation of pain prevention and management.

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Papers, etc., Registered in KOARA 【 Display / hide 】

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Reviews, Commentaries, etc. 【 Display / hide 】

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Presentations 【 Display / hide 】

  • 早産児の音声言語処理の脳機能発達

    ARIMITSU Takeshi

    第21回日本光脳機能イメージング学会 (星陵会館（東京都千代田区）) , 

    2018.07
    , 

    Oral presentation (invited, special)

  • 在胎週数によって生後日齢が睡眠時の脳領域の結合に及ぼす影響は異なる

    ARIMITSU Takeshi

    日本周産期・新生児医学会 (東京国際フォーラム（東京都千代田区）) , 

    2018.07
    , 

    Oral presentation (general)

  • 早産児の脳を育むNICUの音環境デザイン

    ARIMITSU Takeshi

    神奈川こども　第4回新生児発達支援セミナー (神奈川県立こども医療センター（神奈川県横浜市）) , 

    2018.05
    , 

    Oral presentation (invited, special)

  • 近赤外分光法を用いた新生児の脳機能発達の検討

    ARIMITSU Takeshi

    第一回新生児基礎TR研究会, 

    2018.02
    , 

    Oral presentation (general)

  • 音環境で赤ちゃんを育む

    ARIMITSU Takeshi

    第20回新生児呼吸療法モニタリングフォーラム (大町市文化会館（長野県大町市）) , 

    2018.02
    , 

    Oral presentation (invited, special)

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Research Projects of Competitive Funds, etc. 【 Display / hide 】

  • 親と環境が早産児の高次脳機能発達を促す機序の近赤外分光法と行動指標による研究

    2019.04
    -
    2023.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Principal investigator

  • 近赤外分光法と視線計測を用いた脳室周囲白質軟化症の高次脳機能障害の解明

    2015.04
    -
    Present

    Grant-in-Aid for Scientific Research, Principal investigator

  • 非侵襲的脳機能測定法を用いた脳室周囲白質軟化症における認知・発達メカニズムの解明

    2013.04
    -
    2015.03

    Grant-in-Aid for Scientific Research, Principal investigator

  • The regulation of voltage-gated ion channels expressed on neuronal dendrites in hypoxic-ischemic encephalopathy

    2009.04
    -
    2013.03

    Grant-in-Aid for Scientific Research, ARIMITSU, Takeshi, Principal investigator

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Courses Taught 【 Display / hide 】

  • LECTURE SERIES, PEDIATRICS

    2024

  • LECTURE SERIES, PEDIATRICS

    2023

  • LECTURE SERIES, PEDIATRICS

    2022

  • LECTURE SERIES, PEDIATRICS

    2021

  • LECTURE SERIES, PEDIATRICS

    2020

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Courses Previously Taught 【 Display / hide 】

  • 診断学実習

    慶應義塾大学医学部

    2018.04
    -
    2019.03

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Educational Activities and Special Notes 【 Display / hide 】

  • 第19回慶應義塾大学病院臨床研修指導医養成ワークショップ修了

    2014.06
    -
    Present

    , Special Affairs

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Memberships in Academic Societies 【 Display / hide 】

  • 公益社団法人　日本小児科学会

    　

  • 一般社団法人　日本新生児成育医学会

    　

  • 一般社団法人　日本周産期・新生児医学会

    　
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Committee Experiences 【 Display / hide 】

  • 2018.06
    -
    Present

    社会保険委員会委員, 日本新生児成育医学会

  • 2018.06
    -
    Present

    社会保険委員会幹事, 日本周産期・新生児医学会

  • 2016.06
    -
    2018.05

    社会保険委員会委員, 日本新生児成育医学会

  • 2016.06
    -
    2018.05

    社会保険委員会幹事, 日本周産期・新生児医学会

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