Sakamoto, Yoshiaki

写真a

Affiliation

School of Medicine, Department of Plastic and Reconstructive Surgery （Shinanomachi）

Position

Senior Assistant Professor (Non-tenured)/Assistant Professor (Non-tenured)
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Career 【 Display / hide 】

  • 2005.04
    -
    2006.03

    Tokyo Dental College Ichikawa General Hospital, 初期臨床研修医

  • 2006.04
    -
    2007.03

    Keio University Hospital, 初期臨床研修医

  • 2007.04
    -
    2008.05

    Keio University School of Medicine, Department of Plastic and Reconstructive Surgery, 専修医

  • 2008.06
    -
    2009.05

    Tokyo Metroporitan Kiyose Children's Hospital, Department of Pediatric Surgery, 医員

  • 2009.06
    -
    2010.03

    Keio University School of Medicine, Department of Plastic and Reconstructive Surgery, 専修医

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Academic Background 【 Display / hide 】

  • 2005.03

    Keio University, Faculty of Medicine

    University, Graduated

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Academic Degrees 【 Display / hide 】

  • 博士, Keio University, Dissertation, 2014.12

    頭蓋骨感染動物モデルにおける抗生剤含有リン酸カルシウム骨セメントの有用性の評価

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Licenses and Qualifications 【 Display / hide 】

  • 日本形成外科学会専門医, 2012.04

  • 日本頭蓋顎顔面外科学会専門医, 2015.12

  • 皮膚腫瘍外科指導専門医, 2015.12

  • Asian Pacific Craniofacial Active member, 2016.12

  • Internal Society of Craniofacial Surgery Active member, 2017.09

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Matters concerning Career Achievements 【 Display / hide 】

  • 2016.04
    -
    Present

    日本シミュレーション外科学会　理事

  • 2017.04
    -
    Present

    日本頭蓋顎顔面学会　代議員

  • 2019.10
    -
    Present

    日本形成外科学会 渉外・広報委員会委員

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Research Areas 【 Display / hide 】

  • Life Science / Plastic and reconstructive surgery (Plastic and Reconstructive Surgery)

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Research Keywords 【 Display / hide 】

  • artificial bone

  • Craniomaxillofacial Surgery

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Books 【 Display / hide 】

  • コンパス　顔面骨骨折の治療　ベーシック編

    坂本　好昭　他, 克誠堂出版, 2022.04

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Papers 【 Display / hide 】

  • Influence of Lip Revision Surgery on Facial Growth in Patients with A Cleft Lip

    Kamata M., Sakamoto Y., Ogata H., Sakamoto T., Ishii T., Kishi K.

    Journal of Craniofacial Surgery （Journal of Craniofacial Surgery)  34 （ 4 ） 1203 - 1206 2023.06

    ISSN  10492275

    　View Summary

    Although patients with cleft lip and palate often present with poor maxillary growth because of intrinsic and iatrogenic factors, the surgical influence of lip revision surgery, palatal fistula repair, and pharyngeal flap procedures remains uncertain in contrast to that of primary cleft lip repair and palatoplasty. Therefore, this study aimed to reveal factors inhibiting maxillary growth and inducing later orthognathic surgery. A retrospective analysis was conducted on the data of patients with cleft lip and palate who underwent a series of treatments at Keio University Hospital from 1990 to 2000. We collected data on patient sex, cleft type, number and timing of lip revision surgery, the incidence of palatal fistulae, history of pharyngeal flap procedures, and timing of a repeat bone graft, and reviewed whether these patients underwent orthognathic surgery later in life. Multivariate analysis was conducted using binary logistic regression to extract factors affecting later orthognathic surgery. A total of 52 patients were included in this study. Results showed that revision surgery conducted more than twice was the highest statistically significant predictor of later orthognathic surgery in patients with a cleft lip and palate (P<0.05, odds ratio=43.3), followed by palatal fistula occurrence after cleft palate repair (P<0.05, odds ratio=22.3). Therefore, primary surgical procedure is most important for these patients.

  • An Elderly Patient with Crouzon Syndrome Treated with Monobloc Distraction

    Nakao K., Sakamoto Y., Miwa T., Wakabayashi K., Ishii T., Kishi K.

    Journal of Craniofacial Surgery （Journal of Craniofacial Surgery)  33 （ 8 ） E871 - E874 2022.11

    ISSN  10492275

    　View Summary

    Monobloc advancement by distraction osteogenesis is the treatment of choice in patients with syndromic craniosynostosis. This procedure is usually performed at 18 to 24 months/5 to 10 years of age. Herein, we present the case of a male patient with Crouzon syndrome who underwent monobloc advancement at the age of 62 years. Although the patient lived a normal life (employed, married, and being a father of a daughter), he visited our hospital for surgical improvement in facial esthetics. The patient underwent monobloc advancement by distraction osteogenesis. He was satisfied with the postoperative esthetic improvement and did not experience any major complications. This case highlights the fact that patients with syndromic craniosynostosis desire esthetic improvement and suggests that multidisciplinary treatment involving both the neuro and plastic surgeons is important in such cases.

  • Application of Deep Learning Techniques for Automated Diagnosis of Non-Syndromic Craniosynostosis Using Skull

    Mizutani K., Miwa T., Sakamoto Y., Toda M.

    Journal of Craniofacial Surgery （Journal of Craniofacial Surgery)  33 （ 6 ） 1843 - 1846 2022.09

    ISSN  10492275

    　View Summary

    Abstract Non-syndromic craniosynostosis (NSCS) is a disease, in which a single cranial bone suture is prematurely fused. The early intervention of the disease is associated with a favorable outcome at a later age, so appropriate screening of NSCS is essential for its clinical management. The present study aims to develop a classification and detection system of NSCS using skull X-ray images and a convolutional neural network (CNN) deep learning framework. A total of 56 NSCS cases (scaphocephaly [n = 17], trigonocephaly [n = 28], anterior plagiocephaly [n = 8], and posterior plagiocephaly [n = 3]) and 25 healthy control infants were included in the study. All the cases underwent skull X-rays and computed tomography scan for diagnosis in our institution. The lateral views obtained from the patients were retrospectively examined using a CNN framework. Our CNN model classified the 4 NSCS types and control with high accuracy (100%). All the cases were correctly classified. The proposed CNN model may offer a safe and high-sensitivity screening of NSCS and facilitate early diagnosis of the disease and better neurocognitive outcome for patients.

  • Factors Affecting Optic Nerve Damage in le Fort III Osteotomy: A Retrospective Study

    Noto M., Sakahara D., Sakamoto Y., Imai K.

    Journal of Craniofacial Surgery （Journal of Craniofacial Surgery)  33 （ 6 ） 1865 - 1868 2022.09

    ISSN  10492275

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    The causes of visual impairment following Le Fort osteotomy for syndromic craniosynostosis have not been completely elucidated. The authors investigated the potential causes and means of prevention of optic nerve damage, with particular emphasis on intraoperative blood transfusion volume and operating time. This retrospective study evaluated patients who underwent Le Fort III osteotomy for syndromic craniosynostosis between 2000 and 2020. Data on pupillary reflex, pupil size, operating time, blood transfusion, age at time of surgery, sex, and syndrome type were obtained from medical records. Univariate analysis and multivariate analysis with the level of statistical significance set at P<0.05. For the 86 patients included, the mean values of operating time, amount of blood transfusion based on body weight, amount of blood transfusion per body weight per hour, and age were 6.0 hours (range: 3.5-12.3 h), 30.5 mL/kg (range: 0-322 mL/kg), 5.14 mL/kg/h (range: 0-35.7 mL/kg/h), and 10.0 years (range: 4-38 y), respectively. Crouzon, Apert, and Pfeiffer syndromes were observed in 49, 29, and 8 patients, respectively. Abnormal pupillary findings were observed in 27 patients of whom 25 showed no abnormalities in subsequent visual function and 2 developed blindness. Abnormal pupillary findings correlated with the amount of blood transfused per body weight (P=0.0082) and amount of blood transfused per body weight per hour (P=0.0052). As demonstrated in this study, increased intraoperative bleeding and amount of blood transfused were associated with optic nerve damage, particularly during acute bleeding. Prompt inspection of the pupils following surgery is therefore warranted.

  • The role of surgeon's learning on the outcomes of alveolar bone graft for cleft repair

    Sakamoto Y., Ogata H., Miyamoto J., Kishi K.

    Journal of Plastic, Reconstructive and Aesthetic Surgery （Journal of Plastic, Reconstructive and Aesthetic Surgery)  75 （ 6 ） 1937 - 1941 2022.06

    ISSN  17486815

    　View Summary

    Background and purpose: Teaching cleft repair in the operating room may not sufficiently prepare craniofacial residents to perform the procedure self-reliantly. This study aimed to assess the influence of surgeons’ experience level on the operative time and graft survival ratio after alveolar bone grafts for cleft repair. Subjects and methods: This was a retrospective review of 100 consecutive alveolar bone graft patients treated for unilateral alveolar cleft by one craniofacial surgeon between 2012 and 2019. An alveolar bone graft from the iliac bone was performed using the lateral sliding flap. Sex, age, cleft width, cleft defect volume, and operative time were recorded, and the 1-year postoperative graft survival ratio was calculated. Multiple regression analysis was performed to identify factors that affect the operative time and survival ratio. Results: Factors affecting the operative time were the experience level of the surgeon and the presence of a cleft palate. Factors affecting the graft survival ratio were the cleft defect volume and experience level of the surgeon. In cleft lip and alveolus, the survival ratio was constant, and the operative time stabilised after approximately 20 cases. In cleft lip and palate, more experience was required to master the technique, and the operative time and survival ratio were stabilised only after approximately 40 cases. Conclusion: Surgeons’ experience level influenced the outcomes of alveolar bone grafting. Although surgical training is currently undergoing a paradigm shift from on-the-job training to simulation-based training, clinical experience is critical to be self-sufficient.

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Papers, etc., Registered in KOARA 【 Display / hide 】

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Reviews, Commentaries, etc. 【 Display / hide 】

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Presentations 【 Display / hide 】

  • Plagiocephalyの病態メカニズムの一見解

    Sakamoto Yoshiaki

    第54回日本形成外科学会総会 (徳島) , 

    2011
    , 

    Oral presentation (general)

  • Plagiocephalyの頭蓋変形に蝶形鱗状縫合は関与しているか？：有限要素法を用いたPosterior Coronal Hemiringの検証

    Sakamoto Yoshiaki

    第54回日本形成外科学会総会 (徳島) , 

    2011
    , 

    Oral presentation (general)

  • 新しい内眼角形成術

    Sakamoto Yoshiaki

    第54回日本形成外科学会総会 (徳島) , 

    2011
    , 

    Oral presentation (general)

  • 抗生剤混入リン酸カルシウム骨ペーストの有用性の検討

    Sakamoto Yoshiaki

    第23回慶應形成外科学術同門会 (東京) , 

    2011
    , 

    Oral presentation (general)

  • 症候群性狭頭症に対する中顔面低形成の時期と術式

    Sakamoto Yoshiaki

    第７回　craniosynostosis研究会 (東京) , 

    2011
    , 

    Oral presentation (general)

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Research Projects of Competitive Funds, etc. 【 Display / hide 】

  • ミクロ肉眼解剖による老化に関与する人体アンカリング構造の解明

    2022.04
    -
    2025.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 基盤研究(C), Principal investigator

  • 頭蓋縫合閉鎖に関わるメカノバイオロジーの解明

    2016.04
    -
    2020.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B), Principal investigator

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Awards 【 Display / hide 】

  • 日本頭蓋底外科学会　優秀論文賞

    2018.10, 日本頭蓋底外科学会

    Type of Award： Award from Japanese society, conference, symposium, etc.

  • 日本小児外科学会金賞

    2012.06, 日本小児外科学会, 日本人の臍の成長とその形状変化

  • 日本形成外科学会学術奨励賞

    2012.04, 日本形成外科学会, MoD法　-頭蓋縫合早期癒合症に対する新たな骨延長法-

  • 第46回 日本小児外科学会　金賞

    Sakamoto Yoshiaki, 2009.06, 日本小児外科学会, 臍ヘルニアに対する我々の治療戦略

    Type of Award： Award from Japanese society, conference, symposium, etc.

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Courses Taught 【 Display / hide 】

  • LECTURE SERIES, PLASTIC AND RECONSTRUCTIVE SURGERY

    2023

  • LECTURE SERIES, PLASTIC AND RECONSTRUCTIVE SURGERY

    2022

  • LECTURE SERIES, PLASTIC AND RECONSTRUCTIVE SURGERY

    2021

  • LECTURE SERIES, PLASTIC AND RECONSTRUCTIVE SURGERY

    2020

  • LECTURE SERIES, PLASTIC AND RECONSTRUCTIVE SURGERY

    2019

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Courses Previously Taught 【 Display / hide 】

  • 形成外科

    Keio University

    2015.04
    -
    2016.03
    , 

    Lecture

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Memberships in Academic Societies 【 Display / hide 】

  • 日本形成外科学会, 

    2005.04
    -
    Present

  • 日本頭蓋顎顔面外科学会, 

    2007.04
    -
    Present

  • 日本口蓋裂学会, 

    2007.04
    -
    Present

  • 日本形成外科手術手技学会, 

    2007.04
    -
    Present

  • 日本創傷治癒学会, 

    2012.04
    -
    Present

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Committee Experiences 【 Display / hide 】

  • 2019.10
    -
    Present

    日本形成外科学会 渉外・広報委員会委員, 日本形成外科学会

  • 2019.04
    -
    Present

    日本頭蓋顎顔面外科学会　学術委員, 日本頭蓋顎顔面外科学会

  • 2019.04
    -
    Present

    日本頭蓋顎顔面外科学会　会則検討委員, 日本頭蓋顎顔面外科学会

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