Papers - Nakamura, Masaya

頚椎椎間板ヘルニアによる頚髄症に対する保存療法の有用性と限界―手術例との比較検討―

Matsumoto Morio，Chiba Kazuhiro，Nishizawa Takashi，Nakamura Masaya，Maruiwa Hirofumi，Fujimura Yoshikazu，Toyama Yoshiaki

臨床整形外科 37 ( 2 ) 129-133 2002.02

Research paper (scientific journal), Joint Work

経静脈的patient controlled analgesiaによる脊椎術後疼痛管理

Matsumoto Morio, Chiba Kazuhiro, Nishizawa Takashi, Nakamura Masaya, Toyama Yoshihiro, Hashiguchi Saori

臨床整形外科 37 ( 2 ) 159-162 2002.02

Research paper (scientific journal), Joint Work

頸椎椎間板ヘルニアによる頸髄症に対する保存療法の有用性と限界―手術例との比較検討

Matsumoto Morio, Chiba Kazuhiro, Nishizawa Takashi, Nakamura Masaya, Maruiwa Hirofumi, Fujimura Yoshikazu, Toyama Yoshiaki

臨床整形外科 37 ( 2 ) 129-133 2002.02

Research paper (scientific journal), Joint Work

経静脈的patient controlled analgesiaによる脊椎術後疼痛管理

Matsumoto Morio，Chiba Kazuhiro，Nishizawa Takashi，Nakamura Masaya，Maruiwa Hirofumi，Fujimura Yoshikazu，Toyama Yoshiaki，Hashiguchi Saori

臨床整形外科 37 ( 2 ) 159-162 2002.02

Research paper (scientific journal), Joint Work

特集―中枢神経系の再生に挑む；損傷脊髄への神経幹細胞移植

Nakamura Masaya, Toyama Yoshiaki, Okano Hiroyuki

実験医学 20 ( 9 ) 1301-1306 2002

Research paper (scientific journal), Joint Work

損傷脊髄内サイトカイン・神経栄養因子mRNAの発現の変化

Nakamura Masaya, Okano Hiroyuki, Chiba Kazuhiro, Bregman Bs, Toyama Yoshiaki

日本パラプレジア医学会誌 15 ( 1 ) 126-127 2002

Research paper (scientific journal), Joint Work

成功する胸椎手術―脊髄腫瘍（硬膜内髄外腫瘍）

Nakamura Masaya, Chiba Kazuhiro, Toyama Yoshiaki

整形災害外科 45   651-657 2002

Research paper (scientific journal), Joint Work

特集―再生医療：脊髄損傷に対する神経幹細胞移植

Nakamura Masaya, Toyama Yoshiaki

日本臨床 61 ( 3 ) 463-468 2002

Research paper (scientific journal), Joint Work

脊髄円錐高位の椎間板ヘルニア

Inami Shuuji，Nakamura Masaya，Chiba Kazuhiro，Toyama Yoshiaki

脊椎脊髄ジャーナル 15 ( 4 ) 273-278 2002

Research paper (scientific journal), Joint Work

仙骨全摘後2期的再建を行った脊索腫の2例

Matsumoto Morio, Chiba Kazuhiro, Maruiwa Hirofumi, Nakamura Masaya, Nishizawa Takashi, Toyama Yoshiaki

脊椎・脊髄神経手術手技 4 ( 1 ) 104-106 2002

Research paper (scientific journal), Joint Work

A simple and reliable behavioral analysis of locomotor function after spinal cord injury in mice

Mikami Yuji, Toda Masahiro, Watanabe Masahiko, Nakamura Masaya, Toyama Yoshiaki, Kawakami Yutaka

Journal of Neurosurgery 97 ( 1 SUPPL. ) 142 - 147 2002

ISSN  0022-3085

　View Summary

<p>To establish a simple and reliable method to assess the behavioral function after spinal cord injury (SCI) in mice, the authors used an automated animal movement analysis system, SCANET. Two different SCI lesions were created in adult female BALB/c and C57BL/6 mice by transecting both the posterior columns and the left lateral and anterior funiculi or only the left lateral and anterior funiculi at T-8. Control mice underwent laminectomy only. The SCANET system consists of a cage equipped with two crossing sensor frames arranged at different heights, by which small (MI) and large (M2) horizontal movements and the vertical movement involved in rearing (RG) can be monitored. The authors assessed locomotor function by determining the M1, M2, and RG scores; to this end, they used the SCANET system and a previously established behavior test, the 21-point open-field Basso-Beattie-Bresnahan (BBB) Locomotor Rating Scale. The results indicated that the RG scores were significantly and consistently different between the spinal cord-injured and control mice, irrespective of the mouse strain or injury model, but that MI and M2 scores were not. Moreover, there was a statistically positive correlation between the RG score and the BBB Scale score. For the assessment of locomotor function after SCI, use of the SCANET sytem in behavioral analysis is simple and the method is highly reproducible. The analysis of vertical movement is useful for assessing the recovery of limb function in mice following thoracic hemisection.</p>

L5椎体下縁の骨棘により生じたfar-out syndromeの1例

Okushima Yuuichirou，Chiba Kazuhiro，Matsumoto Morio，Maruiwa Hirofumi，Nakamura Masaya，Nishizawa Takashi，Toyama Yoshiaki

関東整形災害外科学会雑誌 32 ( 5 ) 262-265 2001.10

Research paper (scientific journal), Joint Work

Increase of oligodendrocyte progenitor cells after spinal cord injury

Ishii Ken, Toda Masahiro, Nakai Yoko, Asou Hiroaki, Watanabe Masahiko, Nakamura Masaya, Yato Yoshiyuki, Fujimura Yoshikazu, Kawakami Yutaka, Toyama Yoshiaki, Uyemura Keiichi

Journal of Neuroscience Research 65 ( 6 ) 500 - 507 2001.09

ISSN  0360-4012

　View Summary

<p>The reaction of oligodendrocyte progenitor cells (OPCs) after spinal cord injury (SCI) is poorly understood. In this study, we examined oligodendroglial reactions after contusion SCI in adult rats by immunohistochemistry. OPCs were identified by staining with monoclonal antibodies (mAbs) A2B5 and O4. Each of the A2B5-, O4-positive OPCs and galactocerebroside-positive oligodendrocytes dramatically increased in the lesion of the dorsal posterior funiculus. Bromodeoxyuridine (BrdU) incorporation studies showed that most O4-positive cells in the lesion were labeled with BrdU, suggesting that these OPCs were proliferative. In contrast, the expression of myelin basic protein was decreased in the lesion compared with controls that received laminectomy only. From the injured cord, OPCs were isolated by immunopanning with mAb A2B5. We observed an increased number of OPCs from the injured spinal cords compared with those isolated from controls and unoperated animals. After several days in culture, the OPCs from the lesion expressed galactocerebroside. These results suggest that OPCs are induced and can differentiate following SCI in the adult rat. © 2001 Wiley-Liss, Inc.</p>

• Access to Document (DOI)

Increase of oligodendrocyte progentior cells after spinal cord injury

Ishii Ken, Toda Masahiro, Nakai Yoko, Asou Hiroaki, Watanabe Masahiko, Nakamura Masaya, Yato Yoshiyuki, Fujimura Yoshikazu, Kawakami Yutaka, Toyama Yoshiaki, Uyemura Keiichi

Journal of Neuroscience Research 65 ( 6 ) 500-507 2001.09

Research paper (scientific journal), Joint Work

脊柱管狭窄を伴う頚椎椎間板ヘルニアの手術療法―前後合併手術と後方除圧術との比較―

Maruiwa Hirofumi，Chiba Kazuhiro，Nishizawa Takashi，Nakamura Masaya，Matsumoto Morio，Toyama Yoshiaki

脊椎脊髄ジャーナル 14 ( 9 ) 799-803 2001.09

Research paper (scientific journal), Joint Work

Increase of oligodendrocyte progenitor cells after spinal cord injury

Ishii Ken, Toda Masahiro, Nakai Yoko, Asou Hiroaki, Watanabe Masahiko, Nakamura Masaya, Yato Yoshiyuki, Fujimura Yoshikazu, Kawakami Yutaka, Toyama Yoshiaki, Uyemura Keiichi

Journal of Neuroscience Research 65 ( 6 ) 500-507 2001.09

Research paper (scientific journal), Joint Work

第5腰椎椎体骨棘による第5腰神経根障害に対して腹腔鏡視下骨棘切除を行った1例

Matsumoto Morio，Chiba Kazuhiro，Nishizawa Takashi，Nakamura Masaya，Maruiwa Hirofumi，Toyama Yoshiaki

脊椎脊髄ジャーナル 14 ( 8 ) 112-115 2001.08

Research paper (scientific journal), Joint Work

頚椎症性脊髄症（ヘルニアを含む）に対する腸骨inlay graftによる前方固定術

Maruiwa Hirofumi，Chiba Kazuhiro，Matsumoto Morio，Nakamura Masaya，Nishizawa Takashi，Toyama Yoshiaki

Monthly Book Orthopedics 14 ( 8 ) 1-8 2001.08

Research paper (scientific journal), Joint Work

高齢者の歯突起骨折―その臨床像と治療成績について

Matsumoto Morio，Chiba Kazuhiro，Nishizawa Takashi，Nakamura Masaya，Maruiwa Hirofumi，Fujimura Yoshikazu，Toyama Yoshiaki，Watanabe Kouzou

臨床整形外科 36 ( 7 ) 881-884 2001.07

Research paper (scientific journal), Joint Work

特集／腰椎椎間板ヘルニアの治療―最近の動向；ヘルニアの自然縮小―単純MRIによる観察

Okushima Yuuichirou，Chiba Kazuhiro，Matsumoto Morio，Maruiwa Hirofumi，Nakamura Masaya，Nishizawa Takashi，Nishikawa Yuuji，Toyama Yoshiaki

骨・関節・靭帯 14 ( 7 ) 655-658 2001.07

Research paper (scientific journal), Joint Work