Toda, Masahiro

写真a

Affiliation

School of Medicine, Department of Neurosurgery （Shinanomachi）

Position

Professor
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Academic Degrees 【 Display / hide 】

  • 博士（医学）, 慶應義塾大学

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Books 【 Display / hide 】

  • （脳腫瘍の治療） 神経鞘腫の治療戦略

    田村亮太,戸田正博, 日本臨牀社, 2023.12,  Page： 9

    , Accepted

  • 総論:悪性脳腫瘍の診断・治療の現状と展望

    戸田正博, ニューサイエンス社, 2023.03,  Page： 2

  • ゲノム編集iPS細胞を用いた薬剤・遺伝子デリバリーシステムの開発－グリオーマに対するトランスレーショナルリサーチ

    田村亮太, 戸田正博, ニューサイエンス社, 2023.03,  Page： 4

    , Accepted

  • Stem cell research for the treatment of malignant glioma.

    Tamura R and Toda M, Brain Tumor, InTech, Croatia, 2017

  • Glioma Antigen Glioma: Immunotherapeutic approaches

    Toda M, R Yamanaka (Ed.), In Landes Bioscience, 2012

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Papers 【 Display / hide 】

  • Optimizing perampanel monotherapy for surgically resected brain tumors.

    Hino U, Tamura R, Kosugi K, Ezaki T, Karatsu K, Yamamoto K, Azuna T, Toda M

    Molecular and Clinical Oncology 20 （ 6 ）  2024.04

    Research paper (scientific journal), Joint Work, Accepted,  ISSN  2049-9450

  • Status of alternative angiogenic pathways in glioblastoma resected under and after bevacizumab treatment

    Ezaki1 T, Tanaka T, Tamura R, Ohara K, Yamamoto Y, Takei J, Morimoto Y, Imai R, Kuranai Y, Akasaki Y, Toda M, Murayama Y, Miyake K, Sasaki H

    Brain Tumor Patho 41 （ 2 ） 61 - 72 2024.04

    Research paper (scientific journal), Joint Work, Accepted

  • The role of genetic analysis in distinguishing multifocal and multicentric glioblastomas: An illustrative case.

    Karatsu K, Tamura R, Yo M, Nogawa H, Hino U, Kitamura Y, Ueda R, Toda M

    Case Rep Oncol　2024 （Karger)  17 （ 1 ） 113 - 121 2024.01

    Research paper (scientific journal), Joint Work, Accepted

  • Aneurysmal subarachnoid hemorrhage occurring during sleep: Clinical characteristics and risk factors.

    Inamasu J, Akiyama T, Akaji K, Inaba M, Nishimoto M, Kojima A, Terao S, Hayashi T, Mizutani K, Toda M

    J Stroke Cerebrovasc Dis （Elsevier)  33 （ 4 ） 107591 2024.01

    Joint Work, Accepted

  • Natural history of hearing and tumor growth in vestibular schwannoma in neurofbromatosis type 2‑related schwannomatosis.

    Wakabayashi T, Tamura R, Karatsu K, Hosoya M, Nishiyama T, Inoue Y, Ogawa K, Kanzaki J, Toda M, Ozawa H, Oishi N

    European Archives of Oto-Rhino-Laryngology  2024

    Research paper (scientific journal), Joint Work, Accepted

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Papers, etc., Registered in KOARA 【 Display / hide 】

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Reviews, Commentaries, etc. 【 Display / hide 】

  • Oligodendroglioma, IDH‐mutant and 1p/19q‐codeleted‐prognostic factors, standard of care and chemotherapy, and future perspectives with neoadjuvant strategy.

    Sasaki H, Kitamura Y, Toda M, Hirose Y, Yoshida K

    Brain Tumor Pathology 41 ( 2 ) 43 - 49 2024.04

    Rapid communication, short report, research note, etc. (scientific journal), Joint Work

  • 下垂体腫瘍の分子病理学的メカニズム

    植田　良、戸田正博

    脳神経外科 (医学書院)  51 ( 4 ) 615 - 623 2023.07

    Joint Work

  • グリオーマに対する遺伝子細胞療法・ウィルス療法

    田村亮太、戸田正博

    週刊医学のあゆみ (医歯薬出版株式会社)  285 ( 5 ) 469 - 475 2023.04

    Joint Work,  ISSN  0039-2359

  • Author Correction: A VEGF receptor vaccine demonstrates preliminary efficacy in neurofibromatosis type 2 (Nature Communications, (2019), 10, 1, (5758), 10.1038/s41467-019-13640-1)

    Tamura R., Fujioka M., Morimoto Y., Ohara K., Kosugi K., Oishi Y., Sato M., Ueda R., Fujiwara H., Hikichi T., Noji S., Oishi N., Ogawa K., Kawakami Y., Ohira T., Yoshida K., Toda M.

    Nature Communications (Nature Communications)  11 ( 1 )  2020.12

    　View Summary

    The original version of this Article omitted from the author list the 10th author Tetsuro Hikichi, who is from OncoTherapy Science, Inc., 3-2-1, Sakado, Takatsu-ku, Kawasaki City, Kanagawa, 213-0012, Japan. This author has been added to the article. Consequently, the 5th sentence in the Authors Contributions has been modified to read “RT, MF, YM, KO, KK, YO, MS, NO, HF, TH, and SN collected the data”. Additionally, the following was added to the Competing Interests: TH is an employee of OncoTherapy Science, Inc. This has been corrected in both the PDF and HTML versions of the Article.

  • Erratum: Clinical and histopathological analyses of VEGF receptors peptide vaccine in patients with primary glioblastoma-a case series (BMC Cancer (2020) 20 (196) DOI: 10.1186/s12885-020-6589-x)

    Tamura R., Morimoto Y., Kosugi K., Sato M., Oishi Y., Ueda R., Kikuchi R., Nagashima H., Hikichi T., Noji S., Kawakami Y., Sasaki H., Yoshida K., Toda M.

    BMC Cancer (BMC Cancer)  20 ( 1 )  2020.04

    　View Summary

    Following publication of the original article [1], the authors reported an error in the author group. It was reported that Tetsuro Hikichi was missing and the corrected author group is as follows: Ryota Tamura1, Yukina Morimoto1, Kenzo Kosugi1, Mizuto Sato1, Yumiko Oishi1, Ryo Ueda1, Ryogo Kikuchi2, Hideaki Nagashima1, Tetsuro Hikichi4, Shinobu Noji3, Yutaka Kawakami3, Hikaru Sasaki1, Kazunari Yoshida1 and Masahiro Toda1*The competing interests statement has been updated to: TH is an employee of OncoTherapy Science, Inc. The original article [1] has been corrected.

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Presentations 【 Display / hide 】

  • Phase I/II study of a VEGF receptor vaccine in patients with NF2 related schwannomatosis

    Toda M

    2024 Global NF Conference (Brussels, Belgium) , 

    2024.06
    , 

    Oral presentation (invited, special)

  • 原点　医療模型 KEZLEX と頭蓋矯正ヘルメット

    大野秀晃,戸田正博,三輪点,鰐渕彦,亀田雅博,五味玲,西山健一,竹内和人

    第52回 日本小児神経外科学会 (富山県富山市) , 

    2024.06
    , 

    Oral presentation (invited, special)

  • 頭蓋底手術の進歩と将来

    戸田正博

    第17回杉田記念フォーラム (新潟県五泉市) , 

    2024.05
    -
    2024.06
    , 

    Oral presentation (invited, special), NPO法人脳神経外科手術機器センター

  • Frontline of Gene and Cell Therapy Research in Japan (Organized by the Japanese Society of Gene and Cell Therapy)

    Toda M

    ASGCT 27th Annual Meeting (Baltimore, USA) , 

    2024.05
    , 

    Oral presentation (invited, special)

  • 脳腫瘍治療の将来展望

    戸田正博

    第6回機能脳神経外科懇話会 (埼玉県越谷市) , 

    2024.03
    , 

    Oral presentation (invited, special)

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Research Projects of Competitive Funds, etc. 【 Display / hide 】

  • 遺伝性疾患・神経線維腫症2型に対する革新的治療法（新規免疫療法）の開発

    2024.04
    -
    2026.03

    日本医療研究開発機構, 難治性疾患実用化研究事業, Principal investigator

  • 悪性脳腫瘍に対するウイルス搭載iPS細胞を用いた新規治療の開発

    2024.04
    -
    2026.03

    MEXT,JSPS , Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research（B）, Principal investigator

  • ゲノム編集iPS細胞由来神経幹細胞を用いた悪性神経膠腫に対する遺伝子幹細胞療法の実用化開発

    2023.04
    -
    2025.03

    日本医療研究開発機構, 革新的がん医療実用化研究事業, Principal investigator

  • 悪性脳腫瘍に対するウイルス搭載iPS細胞を用いた新規治療の開発

    2021.04
    -
    2024.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Principal investigator

  • 遺伝性疾患・神経線維腫症2型に対する革新的治療法（新規免疫療法）の開発

    2021.04
    -
    2023.03

    日本医療研究開発機構, 革新的がん医療実用化研究事業, Principal investigator

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Intellectual Property Rights, etc. 【 Display / hide 】

  • THERAPEUTIC AGENT USING GENOME-EDITED PLURIPOTENT STEM CELL

    Date applied： 2020-063477  2021.03 

    Date announced： WO 2021/201100 A1  2021.10 

    Patent

  • 脳腫瘍幹細胞を用いた治療薬スクリーニング法

    Date applied： 特願2019-052704  2019.03 

    Patent, Joint

  • 多能性幹細胞を用いた自殺遺伝子脳腫瘍治療薬

    Date applied： 2019-554440  2018.11 

    Date issued： 7150233 

    Date registered： 2022.09

  • Peptide vaccine and peptide vaccine composition for cranial nerve disease

    Date applied： 2019-518906  2018.05 

    Date issued： 7168228 

    Date registered： 2022.10

  • 脳腫瘍治療用細胞製剤

    Date applied： 特願2019－517657  2018.05 

    Date issued： 特許第7051060 

    Date registered： 2022.04

    Patent

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Courses Taught 【 Display / hide 】

  • NEUROSURGERY: SEMINAR

    2024

  • NEUROSURGERY: PRACTICE

    2024

  • NEUROSURGERY

    2024

  • LECTURE SERIES, NEUROSURGERY

    2024

  • CLINICAL CLERKSHIP IN NEUROSURGERY

    2024

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Courses Previously Taught 【 Display / hide 】

  • Surgical simulation in Neurosurgery

    Keio University

    2015.04
    -
    2016.03

  • pituitary tumor

    Keio University

    2015.04
    -
    2016.03
    , 

    Lecture

  • Topics in Neurosurgery

    Keio University

    2015.04
    -
    2016.03
    , 

    Full academic year, Lecture

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Media Coverage 【 Display / hide 】

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