KEIO RESEARCHERS INFORMATION SYSTEM

Academic Degrees 【 Display / hide 】

Academic Degrees 【 Display / hide 】

• 博士（医学）, 慶應義塾大学

Books 【 Display / hide 】

Books 【 Display / hide 】

• Stem cell research for the treatment of malignant glioma.

  Tamura R and Toda M, Brain Tumor, InTech, Croatia, 2017

• Glioma Antigen Glioma: Immunotherapeutic approaches

  Toda M, R Yamanaka (Ed.), In Landes Bioscience, 2012

• Brain tumor stem cells and anti-angiogenetic therapy

  Saito K, Yoshida K, Toda M, Cancer Stem Cells, The Cutting　Edge Stanley Shostak (Ed.), InTech, Croatia, 2011

  Contact page： 229-246

• Immunotherapy targeted at brain cancer stem cells

  Toda M, Brain Tumor Immunotherapy, The Open Cancer Immunology Journal Terry Lichtor (Ed.), Bentham open,, 2010

  Contact page： 48-50

• Treatment of metastatic brain tumors with a replication-competent multi-mutated herpes simplex virus-1.

  Toda M, Uyemura K, Kawase T, Rabkin SD, Martuza RL, Neural Development, Springer-Verlag, 1999

  Contact page： 521-525

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Papers 【 Display / hide 】

Papers 【 Display / hide 】

• Difference in the hypoxic immunosuppressive microenvironment of patients with neurofibromatosis type 2 schwannomas and sporadic schwannomas.

  Tamura R, Morimoto Y, Sato M, Kuranari Y, Oishi Y, Kosugi K, Yoshida K, Toda M

  J Neurooncol 146 （ 2 ） 265 - 273 2020

  Research paper (scientific journal), Joint Work

• Prediction of postoperative recurrence of chronic subdural hematoma using quantitative volumetric analysis in conjunction with computed tomography texture analysis.

  Kanazawa T, Takahashi S, Minami Y, Jinzaki M, Toda M, Yoshida K

  J Clin Neurosci 72   270 - 276 2020

  Research paper (scientific journal), Joint Work

• Efficacy of a topical gelatin-thrombin hemostatic matrix, FLOSEAL®, in intracranial tumor resection.

  Kamamoto D, Kanazawa T, Ishihara E, Yanagisawa K, Tomita H, Ueda R, Jinzaki M, Yoshida K, Toda M

  72   270 - 276 2020

  Research paper (scientific journal), Joint Work

• Surgical outcomes of anterior cerebellopontine angle meningiomas using the anterior transpetrosal approach compared with the lateral suboccipital approach.

  Hassaan SA, Tamura R, Morimoto Y, Kosugi K, Mahmoud M, Abokerasha A, Moussa A, Toda M, Yoshida K

  Acta Neurochir (Wien)   2020

  Research paper (scientific journal), Joint Work

• Quantitative assessment and clinical relevance of VEGFRs-positive tumor cells in refractory brain tumors.

  Tamura R, Sato M, Morimoto Y, Ohara K, Kosugi K, Oishi Y, Kuranari Y, Murase M, Yoshida K, Toda M

  Exp Mol Pathol   2020

  Research paper (scientific journal), Joint Work

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Papers, etc., Registered in KOARA 【 Display / hide 】

Papers, etc., Registered in KOARA 【 Display / hide 】

• Investigation of immunovirotherapy for malignant brain tumors using neural stem cells and oncolytic viruses

  Toda, Masahiro

  科学研究費補助金研究成果報告書 2018

• Gene-cell therapy using iPS cells for the treatment of brain tumor

  Toda, Masahiro

  科学研究費補助金研究成果報告書 2017

• Biomarkers for evaluation of clinical activity of VEGFR-targeted vaccines against malignant glioma patients

  Toda, Masahiro

  科学研究費補助金研究成果報告書 2017

• Cell therapy by human iPSC-transplantation for functional repair of stroke-damaged neural circuitry and malignant brain tumor

  Toda, Masahiro

  科学研究費補助金研究成果報告書 2016

• Identification of glioma oncoantigens for the development of the vaccine

  Toda, Masahiro

  科学研究費補助金研究成果報告書 2015

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Reviews, Commentaries, etc. 【 Display / hide 】

Reviews, Commentaries, etc. 【 Display / hide 】

• Current Understanding of Lymphatic Vessels in the Central Nervous System

  Tamura R, Yoshida K, Toda M.

  Neurosurg Rev　  2019

  Introduction and explanation (scientific journal), Joint Work

  • Access to Document (DOI)

• Recent progress in the research of suicide gene therapy for malignant glioma.

  Tamura R, Miyoshi H, Yoshida K, Okano H, Toda M

  Neurosurg Rev  2019

  Introduction and explanation (scientific journal), Joint Work

  • Access to Document (DOI)

• Stem cell-based therapies for neurological disorders.

  Tamura R , Toda M

  Cell and Tissue Engineering 2   24 - 47 2018

  Introduction and explanation (scientific journal), Joint Work

• Glioma Stem Cells and Immunotherapy for the Treatment of Malignant Gliomas

  Toda M

  ISRN Oncology 2013   1 - 13 2013

  Introduction and explanation (scientific journal), Single Work

• Glioma Antigen

  Toda M

  Journal of Cancer Research Updates  1 ( 1 ) 28 - 38 2012

  Introduction and explanation (scientific journal), Single Work

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Presentations 【 Display / hide 】

Presentations 【 Display / hide 】

• Suicide gene cell therapy for malignant glioma using genome-edited human induced pluripotent stem cells

  Toda M,Tamura R,Miyoshi H,MorimotoY,Sampetrean O,Saya H,Okano H,Yoshida K

  The 25th Annual Meeting of Japan Society of Gene and Cell Therapy (東京) , 2019.07, Oral Presentation(general)

• 側頭骨内顔面神経腫瘍に対する手術法の検討

  大石直樹、戸田正博、矢澤真樹、小川　郁

  第31回日本頭蓋底外科学会 (神戸) , 2019.07, Symposium, Workshop, Panelist (public offering)

• 脊索腫におけるVEGF受容体発現解析とペプチドワクチンの臨床試験

  森本佑紀奈、戸田正博、田村亮太、尾原健太郎、大石裕美子、吉田一成

  第31回日本頭蓋底外科学会 (神戸) , 2019.07, Symposium, Workshop, Panelist (public offering)

• 再手術症例における経鼻内視鏡下頭蓋底手術時の頭蓋底再建について

  小澤宏之、関水真理子、中原奈々、齋藤　真、中村伸太郎、戸田正博、小川　郁

  第31回日本頭蓋底外科学会 (神戸) , 2019.07, Symposium, Workshop, Panelist (public offering)

• 再発頭蓋底髄膜腫に対する手術成績の解析と経鼻内視鏡手術の役割について

  蔵成勇紀、戸田正博、吉田一成

  第31回日本頭蓋底外科学会 (神戸) , 2019.07, Symposium, Workshop, Panelist (public offering)

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Research Projects of Competitive Funds, etc. 【 Display / hide 】

Research Projects of Competitive Funds, etc. 【 Display / hide 】

• 遺伝性疾患・神経線維腫症２型に対する革新的治療法（新規免疫療法）の開発

  2019.04

  -

  2021.03

  橋渡し研究戦略的推進プログラム・シーズB

• 自殺遺伝子CD-UPRTゲノム編集iPS細胞を用いた遺伝子治療

  2018.06

  -

  2021.03

  MEXT,JSPS, Grant-in-Aid for Scientific Research, 戸田　正博, Grant-in-Aid for Challenging Research (Exploratory) , Principal Investigator

• 脳腫瘍に対するゲノム編集iPS細胞を用いた遺伝子治療

  2018.04

  -

  2019.03

  AMED橋渡し研究戦略的推進プログラム, 戸田正博, No Setting, Principal Investigator

• 悪性神経膠腫に対するゲノム編集iPS細胞を用いた遺伝子細胞治療

  2018.04

  -

  2019.03

  慶應義塾大学, 坂口光洋記念慶應義塾医学振興基金平成30年度慶應義塾大学医学研究助成, 田村亮太, Research grant, Co-investigator

• 悪性神経膠腫に対する革新的ワクチン療法の開発

  2017.04

  -

  2020.03

  MEXT,JSPS, Grant-in-Aid for Scientific Research, 戸田　正博, Grant-in-Aid for Scientific Research (B), Principal Investigator

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Intellectual Property Rights, etc. 【 Display / hide 】

Intellectual Property Rights, etc. 【 Display / hide 】

• 脳腫瘍幹細胞を用いた治療薬スクリーニング法

  Application No.： 特願2019-052704  2019.03 

  Patent, Joint, National application

• 多能性幹細胞を用いた自殺遺伝子脳腫瘍治療薬

  Application No.： 特願２０１７－２２３２０２  2017.11 

  Patent, Joint, PCT international application

• 脳神経疾患に対するペプチドワクチン及びペプチドワクチン組成物

  Application No.： 特願２０１７－１００３６１  2017.05 

  Patent, Single, PCT international application

• 神経幹細胞の分離方法及び増殖促進方法

  Application No.： 特願2008-014243  2008.01 

  Patent, Joint, National application

• 神経損傷の治療薬

  Application No.： 特願2003-128508  2003.05 

  Registration No.： 特許第3607271号  2004.10

  Patent, Joint, PCT international application

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Courses Taught 【 Display / hide 】

Courses Taught 【 Display / hide 】

• LECTURE SERIES, NEUROSURGERY

  2020

• CLINICAL CLERKSHIP IN NEUROSURGERY

  2020

• CLINICAL CLERKSHIP IN NEUROSURGERY

  2019

• LECTURE SERIES, NEUROSURGERY

  2019

Courses Previously Taught 【 Display / hide 】

Courses Previously Taught 【 Display / hide 】

• Surgical simulation in Neurosurgery

  Keio University, 2015

• pituitary tumor

  Keio University, 2015, Lecture

• Topics in Neurosurgery

  Keio University, 2015, Full academic year, Lecture