Toda, Masahiro

写真a

Affiliation

School of Medicine, Department of Neurosurgery (Shinanomachi)

Position

Professor
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Academic Degrees 【 Display / hide 】

  • 博士（医学）, 慶應義塾大学

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Books 【 Display / hide 】

  • （脳腫瘍の治療） 神経鞘腫の治療戦略

    田村亮太,戸田正博, 日本臨牀社, 2023.12,  Page： 9

    , Accepted

  • 総論:悪性脳腫瘍の診断・治療の現状と展望

    戸田正博, ニューサイエンス社, 2023.03,  Page： 2

  • ゲノム編集iPS細胞を用いた薬剤・遺伝子デリバリーシステムの開発－グリオーマに対するトランスレーショナルリサーチ

    田村亮太, 戸田正博, ニューサイエンス社, 2023.03,  Page： 4

    , Accepted

  • Stem cell research for the treatment of malignant glioma.

    Tamura R and Toda M, Brain Tumor, InTech, Croatia, 2017

  • Glioma Antigen Glioma: Immunotherapeutic approaches

    Toda M, R Yamanaka (Ed.), In Landes Bioscience, 2012

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Papers 【 Display / hide 】

  • Variable anatomical features of acromegaly in the nasal cavity and paranasal sinuses: implications for endoscopic endonasal transsphenoidal surgery

    Takahara K,Tamura R, Isomura E, Kitamura Y, Ueda R, Toda M

    Acta Neurochir (Wien) (Wien, Springer)  166 ( 1 ) 408 2024.10

    Research paper (scientific journal), Joint Work, Accepted

  • Risk factors of postoperative trigeminal neuropathy in surgical treatment of trigeminal schwannomas

    Shibao S, Ueda R, Toda M, Yoshida K

    Acta Neurochir (Wien) (Wien, Springer)  166 ( 1 ) 387 2024.09

    Research paper (scientific journal), Joint Work, Accepted

  • Development of microsurgical forceps equipped with haptic technology for in situ differentiation of brain tumors during microsurgery

    Ezaki T, Kishima K, Shibao S, Matsunaga T, Pareira S E , Kitamura Y, Nakayama Y, Tsuda N, Takahara K, Iwama T, Sampetrean O, Toda M, Ohnishi K, Shimono T, Sasaki H

    Sci Rep (Springer Nature)  14 ( 1 ) 21430 2024.09

    Research paper (scientific journal), Joint Work, Accepted

  • Upright CT-based evaluation of the effects of posture on skull-base reconstruction after endoscopic endonasal surgery

    Takahara K, Mizutani K,Yamada Y, Yamada M, Yokoyama Y, Yoshida K, Kosugi K, Ueda R, Toda M, Jinzaki M

    Sci Rep (Springer Nature)  14 ( 1 ) 20303 2024.09

    Accepted

  • Natural history of hearing and tumor growth in vestibular schwannoma in neurofbromatosis type 2‑related schwannomatosis.

    Wakabayashi T, Tamura R, Karatsu K, Hosoya M, Nishiyama T, Inoue Y, Ogawa K, Kanzaki J, Toda M, Ozawa H, Oishi N

    Eur Arch Otorhinolaryngol 281 ( 6 ) 4175 - 4182 2024.08

    Research paper (scientific journal), Joint Work, Accepted

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Papers, etc., Registered in KOARA 【 Display / hide 】

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Reviews, Commentaries, etc. 【 Display / hide 】

  • Oligodendroglioma, IDH‐mutant and 1p/19q‐codeleted‐prognostic factors, standard of care and chemotherapy, and future perspectives with neoadjuvant strategy.

    Sasaki H, Kitamura Y, Toda M, Hirose Y, Yoshida K

    Brain Tumor Pathology 41 ( 2 ) 43 - 49 2024.04

    Rapid communication, short report, research note, etc. (scientific journal), Joint Work

  • 下垂体腫瘍の分子病理学的メカニズム

    植田　良、戸田正博

    脳神経外科 (医学書院)  51 ( 4 ) 615 - 623 2023.07

    Joint Work

  • グリオーマに対する遺伝子細胞療法・ウィルス療法

    田村亮太、戸田正博

    週刊医学のあゆみ (医歯薬出版株式会社)  285 ( 5 ) 469 - 475 2023.04

    Joint Work,  ISSN  0039-2359

  • Author Correction: A VEGF receptor vaccine demonstrates preliminary efficacy in neurofibromatosis type 2 (Nature Communications, (2019), 10, 1, (5758), 10.1038/s41467-019-13640-1)

    Tamura R., Fujioka M., Morimoto Y., Ohara K., Kosugi K., Oishi Y., Sato M., Ueda R., Fujiwara H., Hikichi T., Noji S., Oishi N., Ogawa K., Kawakami Y., Ohira T., Yoshida K., Toda M.

    Nature Communications (Nature Communications)  11 ( 1 )  2020.12

    　View Summary

    The original version of this Article omitted from the author list the 10th author Tetsuro Hikichi, who is from OncoTherapy Science, Inc., 3-2-1, Sakado, Takatsu-ku, Kawasaki City, Kanagawa, 213-0012, Japan. This author has been added to the article. Consequently, the 5th sentence in the Authors Contributions has been modified to read “RT, MF, YM, KO, KK, YO, MS, NO, HF, TH, and SN collected the data”. Additionally, the following was added to the Competing Interests: TH is an employee of OncoTherapy Science, Inc. This has been corrected in both the PDF and HTML versions of the Article.

  • Erratum: Clinical and histopathological analyses of VEGF receptors peptide vaccine in patients with primary glioblastoma-a case series (BMC Cancer (2020) 20 (196) DOI: 10.1186/s12885-020-6589-x)

    Tamura R., Morimoto Y., Kosugi K., Sato M., Oishi Y., Ueda R., Kikuchi R., Nagashima H., Hikichi T., Noji S., Kawakami Y., Sasaki H., Yoshida K., Toda M.

    BMC Cancer (BMC Cancer)  20 ( 1 )  2020.04

    　View Summary

    Following publication of the original article [1], the authors reported an error in the author group. It was reported that Tetsuro Hikichi was missing and the corrected author group is as follows: Ryota Tamura1, Yukina Morimoto1, Kenzo Kosugi1, Mizuto Sato1, Yumiko Oishi1, Ryo Ueda1, Ryogo Kikuchi2, Hideaki Nagashima1, Tetsuro Hikichi4, Shinobu Noji3, Yutaka Kawakami3, Hikaru Sasaki1, Kazunari Yoshida1 and Masahiro Toda1*The competing interests statement has been updated to: TH is an employee of OncoTherapy Science, Inc. The original article [1] has been corrected.

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Presentations 【 Display / hide 】

  • Phase I/II study of a VEGF receptor vaccine in patients with NF2 related schwannomatosis

    Toda M

    2024 Global NF Conference (Brussels, Belgium) , 

    2024.06
    , 

    Oral presentation (invited, special)

  • Prognostic Significance of Preoperative Neutrophil-to-Lymphocyte Ratio in Surgically Resected Schwannomas.

    2024 Global NF Conference (Brussels, Belgium) , 

    2024.06
    , 

    Oral presentation (invited, special)

  • 原点　医療模型 KEZLEX と頭蓋矯正ヘルメット

    大野秀晃,戸田正博,三輪点,鰐渕彦,亀田雅博,五味玲,西山健一,竹内和人

    第52回 日本小児神経外科学会 (富山県富山市) , 

    2024.06
    , 

    Oral presentation (invited, special)

  • 頭蓋底手術の進歩と将来

    戸田正博

    第17回杉田記念フォーラム (新潟県五泉市) , 

    2024.05
    -
    2024.06
    , 

    Oral presentation (invited, special), NPO法人脳神経外科手術機器センター

  • Gene therapy for brain tumors using genome-edited iPS cells.

    M.Toda

    ASGCT 27th Annual Meeting (Baltimore) , 

    2024.05
    , 

    Oral presentation (invited, special)

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Research Projects of Competitive Funds, etc. 【 Display / hide 】

  • 悪性脳腫瘍に対する新規ゲノム編集技術を用いた個別化遺伝子細胞治療の開発

    2024.04
    -
    2027.03

    基盤研究(B), Principal investigator

  • 遺伝性疾患・神経線維腫症2型に対する革新的治療法（新規免疫療法）の開発

    2024.04
    -
    2026.03

    日本医療研究開発機構, 難治性疾患実用化研究事業, Principal investigator

  • 悪性脳腫瘍に対するウイルス搭載iPS細胞を用いた新規治療の開発

    2024.04
    -
    2026.03

    MEXT,JSPS , Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research（B）, Principal investigator

  • ゲノム編集iPS細胞由来神経幹細胞を用いた悪性神経膠腫に対する遺伝子幹細胞療法の実用化開発

    2023.04
    -
    2025.03

    日本医療研究開発機構, 革新的がん医療実用化研究事業, Principal investigator

  • 悪性脳腫瘍に対するウイルス搭載iPS細胞を用いた新規治療の開発

    2021.04
    -
    2024.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Principal investigator

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Intellectual Property Rights, etc. 【 Display / hide 】

  • THERAPEUTIC AGENT USING GENOME-EDITED PLURIPOTENT STEM CELL

    Date applied： 2020-063477  2021.03 

    Date announced： WO 2021/201100 A1  2021.10 

    Patent

  • 脳腫瘍幹細胞を用いた治療薬スクリーニング法

    Date applied： 特願2019-052704  2019.03 

    Patent, Joint

  • 多能性幹細胞を用いた自殺遺伝子脳腫瘍治療薬

    Date applied： 2019-554440  2018.11 

    Date issued： 7150233 

    Date registered： 2022.09

  • Suicide gene therapeutic agent for brain tumors using pluripotent stem cell

    Date applied： 16/765257  2018.11 

    Date announced： US20210369785A1  2021.12 

    Date issued： US12090172B2 

    Date registered： 2024.09

    Patent

  • Peptide vaccine and peptide vaccine composition for cranial nerve disease

    Date applied： 2019-518906  2018.05 

    Date issued： 7168228 

    Date registered： 2022.10

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Courses Taught 【 Display / hide 】

  • NEUROSURGERY: SEMINAR

    2024

  • NEUROSURGERY: PRACTICE

    2024

  • NEUROSURGERY

    2024

  • LECTURE SERIES, NEUROSURGERY

    2024

  • CLINICAL CLERKSHIP IN NEUROSURGERY

    2024

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Courses Previously Taught 【 Display / hide 】

  • Topics in Neurosurgery

    Keio University

    2015.04
    -
    2016.03
    , 

    Full academic year, Lecture

  • Surgical simulation in Neurosurgery

    Keio University

    2015.04
    -
    2016.03

  • pituitary tumor

    Keio University

    2015.04
    -
    2016.03
    , 

    Lecture

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Media Coverage 【 Display / hide 】

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