Toda, Masahiro

写真a

Affiliation

School of Medicine, Department of Neurosurgery (Shinanomachi)

Position

Professor
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Academic Degrees 【 Display / hide 】

  • 博士（医学）, 慶應義塾大学

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Books 【 Display / hide 】

  • （脳腫瘍の治療） 神経鞘腫の治療戦略

    田村亮太,戸田正博, 日本臨牀社, 2023.12,  Page： 9

    , Accepted

  • 総論:悪性脳腫瘍の診断・治療の現状と展望

    戸田正博, ニューサイエンス社, 2023.03,  Page： 2

  • ゲノム編集iPS細胞を用いた薬剤・遺伝子デリバリーシステムの開発－グリオーマに対するトランスレーショナルリサーチ

    田村亮太, 戸田正博, ニューサイエンス社, 2023.03,  Page： 4

    , Accepted

  • Stem cell research for the treatment of malignant glioma.

    Tamura R and Toda M, Brain Tumor, InTech, Croatia, 2017

  • Glioma Antigen Glioma: Immunotherapeutic approaches

    Toda M, R Yamanaka (Ed.), In Landes Bioscience, 2012

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Papers 【 Display / hide 】

  • Gene therapy and genome-editing for schwannoma in NF2-related schwannomatosis: current understanding and future directions

    Tamura R, Yo M, Toda M

    J Neurooncol (Boston : M. Nijhoff)   2025.03

    Accepted

  • Angiographical Investigation of Vagal and Carotid Body Paragangliomas

    Yamamoto K, Akiyama T, Mizutani K, Ozawa H, Toda M

    J Neuroendovasc Ther (Nihon Nō Shinkei Kekkannai Chiryō Gakkai)  19 ( 1 )  2025.03

  • Anterior transpetrosal approach

    田村亮太、戸田正博

    脳神経外科速報 (メディカ出版)  35 ( 2 ) 192 - 203 2025.02

    Research paper (scientific journal)

  • Optimal Delivery of Pain Management in Schwannomatosis: A Literature Review

    Hino U, Tamura R, Toda M

    Ther Clin Risk Manag (Albany, Auckland : Dove Medical Press)  2025 ( 21 ) 61 - 68 2025.01

    Research paper (scientific journal), Joint Work, Accepted

  • A Cautionary Note on the Indication for Deep Brain Stimulation in Parkinsonism Patients with SLC9A6 Gene Mutations

    Okusa S,Toda M

    J Mov Di (ML Communications)   2025

    Research paper (scientific journal)

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Papers, etc., Registered in KOARA 【 Display / hide 】

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Reviews, Commentaries, etc. 【 Display / hide 】

  • Oligodendroglioma, IDH‐mutant and 1p/19q‐codeleted‐prognostic factors, standard of care and chemotherapy, and future perspectives with neoadjuvant strategy.

    Sasaki H, Kitamura Y, Toda M, Hirose Y, Yoshida K

    Brain Tumor Pathology 41 ( 2 ) 43 - 49 2024.04

    Rapid communication, short report, research note, etc. (scientific journal), Joint Work

  • 下垂体腫瘍の分子病理学的メカニズム

    植田　良、戸田正博

    脳神経外科 (医学書院)  51 ( 4 ) 615 - 623 2023.07

    Joint Work

  • グリオーマに対する遺伝子細胞療法・ウィルス療法

    田村亮太、戸田正博

    週刊医学のあゆみ (医歯薬出版株式会社)  285 ( 5 ) 469 - 475 2023.04

    Joint Work,  ISSN  0039-2359

  • Author Correction: A VEGF receptor vaccine demonstrates preliminary efficacy in neurofibromatosis type 2 (Nature Communications, (2019), 10, 1, (5758), 10.1038/s41467-019-13640-1)

    Tamura R., Fujioka M., Morimoto Y., Ohara K., Kosugi K., Oishi Y., Sato M., Ueda R., Fujiwara H., Hikichi T., Noji S., Oishi N., Ogawa K., Kawakami Y., Ohira T., Yoshida K., Toda M.

    Nature Communications (Nature Communications)  11 ( 1 )  2020.12

    　View Summary

    The original version of this Article omitted from the author list the 10th author Tetsuro Hikichi, who is from OncoTherapy Science, Inc., 3-2-1, Sakado, Takatsu-ku, Kawasaki City, Kanagawa, 213-0012, Japan. This author has been added to the article. Consequently, the 5th sentence in the Authors Contributions has been modified to read “RT, MF, YM, KO, KK, YO, MS, NO, HF, TH, and SN collected the data”. Additionally, the following was added to the Competing Interests: TH is an employee of OncoTherapy Science, Inc. This has been corrected in both the PDF and HTML versions of the Article.

  • Erratum: Clinical and histopathological analyses of VEGF receptors peptide vaccine in patients with primary glioblastoma-a case series (BMC Cancer (2020) 20 (196) DOI: 10.1186/s12885-020-6589-x)

    Tamura R., Morimoto Y., Kosugi K., Sato M., Oishi Y., Ueda R., Kikuchi R., Nagashima H., Hikichi T., Noji S., Kawakami Y., Sasaki H., Yoshida K., Toda M.

    BMC Cancer (BMC Cancer)  20 ( 1 )  2020.04

    　View Summary

    Following publication of the original article [1], the authors reported an error in the author group. It was reported that Tetsuro Hikichi was missing and the corrected author group is as follows: Ryota Tamura1, Yukina Morimoto1, Kenzo Kosugi1, Mizuto Sato1, Yumiko Oishi1, Ryo Ueda1, Ryogo Kikuchi2, Hideaki Nagashima1, Tetsuro Hikichi4, Shinobu Noji3, Yutaka Kawakami3, Hikaru Sasaki1, Kazunari Yoshida1 and Masahiro Toda1*The competing interests statement has been updated to: TH is an employee of OncoTherapy Science, Inc. The original article [1] has been corrected.

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Presentations 【 Display / hide 】

  • Stem cell gene therapy for malignant brain tumors using neural stem cells derivedfrom genome-edited iPS cells

    戸田正博

    第24回日本再生医療学会総会, 

    2025.03
    , 

    Oral presentation (invited, special)

  • 臨床と研究のすゝめ

    戸田正博

    2025 Neurosurgery Conference Collaboration between Tokyo and Yokohama (神奈川県横浜市) , 

    2025.03
    , 

    Oral presentation (invited, special), バクスター・ジャパン株式会社

  • 脳腫瘍手術の今後の展望と新たな治療法の開発

    戸田正博

    令和7年鹿児島大学大学院脳神経外科学同門会総会 (鹿児島県鹿児島市) , 

    2025.01
    , 

    Oral presentation (invited, special), 鹿児島大学大学院脳神経外科学

  • 脳腫瘍治療の将来展望

    戸田正博

    第38回大橋ニューロカンファレンス (東京都新宿区) , 

    2024.12
    , 

    Oral presentation (invited, special), 大橋ニューロカンファレンス/エーザイ株式会社

  • Gene therapy for brain tumors using neural stem cells derived from genome-edited iPS cells

    Toda M

    ESGCT 2024 31st Annual Congress (Rome, Italy) , 

    2024.10
    , 

    Oral presentation (invited, special), European Society of Gene and Cell Therapy

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Research Projects of Competitive Funds, etc. 【 Display / hide 】

  • 悪性脳腫瘍に対する新規ゲノム編集技術を用いた個別化遺伝子細胞治療の開発

    2024.04
    -
    2027.03

    基盤研究(B), Principal investigator

  • 遺伝性疾患・神経線維腫症2型に対する革新的治療法（新規免疫療法）の開発

    2024.04
    -
    2026.03

    日本医療研究開発機構, 難治性疾患実用化研究事業, Principal investigator

  • 悪性脳腫瘍に対するウイルス搭載iPS細胞を用いた新規治療の開発

    2024.04
    -
    2026.03

    MEXT,JSPS , Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research（B）, Principal investigator

  • ゲノム編集iPS細胞由来神経幹細胞を用いた悪性神経膠腫に対する遺伝子幹細胞療法の実用化開発

    2023.04
    -
    2025.03

    日本医療研究開発機構, 革新的がん医療実用化研究事業, Principal investigator

  • 悪性脳腫瘍に対するウイルス搭載iPS細胞を用いた新規治療の開発

    2021.04
    -
    2024.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Principal investigator

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Intellectual Property Rights, etc. 【 Display / hide 】

  • THERAPEUTIC AGENT USING GENOME-EDITED PLURIPOTENT STEM CELL

    Date applied： 2020-063477  2021.03 

    Date announced： WO 2021/201100 A1  2021.10 

    Patent

  • 脳腫瘍幹細胞を用いた治療薬スクリーニング法

    Date applied： 特願2019-052704  2019.03 

    Patent, Joint

  • 多能性幹細胞を用いた自殺遺伝子脳腫瘍治療薬

    Date applied： 2019-554440  2018.11 

    Date issued： 7150233 

    Date registered： 2022.09

  • Suicide gene therapeutic agent for brain tumors using pluripotent stem cell

    Date applied： 16/765257  2018.11 

    Date announced： US20210369785A1  2021.12 

    Date issued： US12090172B2 

    Date registered： 2024.09

    Patent

  • Peptide vaccine and peptide vaccine composition for cranial nerve disease

    Date applied： 2019-518906  2018.05 

    Date issued： 7168228 

    Date registered： 2022.10

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Courses Taught 【 Display / hide 】

  • NEUROSURGERY: SEMINAR

    2025

  • NEUROSURGERY: PRACTICE

    2025

  • NEUROSURGERY

    2025

  • LECTURE SERIES, NEUROSURGERY

    2025

  • ADVANCED NEUROSURGERY

    2025

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Courses Previously Taught 【 Display / hide 】

  • Topics in Neurosurgery

    Keio University

    2015.04
    -
    2016.03
    , 

    Full academic year, Lecture

  • Surgical simulation in Neurosurgery

    Keio University

    2015.04
    -
    2016.03

  • pituitary tumor

    Keio University

    2015.04
    -
    2016.03
    , 

    Lecture

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Media Coverage 【 Display / hide 】

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