KEIO RESEARCHERS INFORMATION SYSTEM

Papers 【 Display / hide 】

Papers 【 Display / hide 】

• Incidence and outcomes of pulmonary artery injury during anatomical lung resection for lung cancer: a nationwide database study in Japan.

  Ichimura H, Yamamoto H, Sato Y, Chida M, Yoshino I, Okada Y, Inoue M, Hoshikawa Y, Ito H, Uramoto H, Shintani Y, Sato T, Chen-Yoshikawa TF, Asakura K, Fukui M, Kawamura M, Sakao Y, Toyooka S

  Surgery today  2026.07

  Joint Work,  ISSN  0941-1291

  • Access to Document (DOI)

• Clinical outcomes of percutaneous cryoablation for pulmonary metastases of soft tissue and bone sarcomas under local anesthesia: a single-institution retrospective cohort study.

  Aoki Y, Kaseda K, Nishida R, Okubo Y, Masai K, Hishida T, Tamura M, Inoue M, Yashiro H, Nakatsuka S, Nakayama R, Yamauchi Y, Izumi Y, Kawamura M, Jinzaki M, Asakura K

  BMC cancer  2026.07

  Joint Work

  • Access to Document (DOI)

• Salvage surgery after epidermal growth factor receptor tyrosine kinase inhibitor therapy for non-small cell lung cancer: a focused narrative review.

  Suzuki S, Suzuki T, Okubo Y, Masai K, Kaseda K, Asakura K

  General thoracic and cardiovascular surgery 74 ( 6 ) 565 - 571 2026.06

  Joint Work,  ISSN  1863-6705

  • Access to Document (DOI)

• Surgical Resection of a Metastatic Lung Tumor with Polypoid Extension Into the Left Atrium Using the Bilateral Transseptal Approach.

  Yano K, Ito T, Asakura K, Harada D, Matsumoto Y, Okubo Y, Masai K, Kaseda K, Kurebayashi Y, Shimizu H

  Annals of thoracic surgery short reports 4 ( 2 ) 460 - 463 2026.06

  Joint Work

  • Access to Document (DOI)

• Spontaneous discrete precipitation pattern formation directed by the coupling of solution permeation and solvent evaporation.

  Aizawa A, Banno T, Asakura K

  Journal of colloid and interface science 722   140767 2026.05

  Joint Work,  ISSN  0021-9797

  • Access to Document (DOI)

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Papers, etc., Registered in KOARA 【 Display / hide 】

Papers, etc., Registered in KOARA 【 Display / hide 】

• Construction of a classification system for pectus excavatum morphology based on image data analysis and development of a new surgical support system

  Asakura, Keisuke

  科学研究費補助金研究成果報告書 2023

• The cytostatic effects of zoledronic acid on ACC-MESO-1 cells

  Asakura, Keisuke

  科学研究費補助金研究成果報告書 2016

• Anti-tumor effects of autophagy induction in malignant pleural mesothelioma

  Asakura, Keisuke

  科学研究費補助金研究成果報告書 2011

• Application of hydrogels for adhesion prevention after thoracotomy

  Asakura, Keisuke

  科学研究費補助金研究成果報告書 2009

• 肺腫瘍の凍結療法

  Asakura, Keisuke

  Journal of the Keio Medical Society (慶應医学会)  85 ( 1 ) 5 - 11 2008.04

  ISSN  03685179

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Presentations 【 Display / hide 】

Presentations 【 Display / hide 】

• 針生検で確定できず外科切除で診断確定した肺リンパ腫様肉芽腫症の1例

  青木 優介, 朝倉 啓介, 實方 秀道, 神谷 侑樹, 木村 征海, 寄森 駿, 中井 猛斗, 杉野 功祐, 渡邉 真祥, 鈴木 嵩弘, 大久保 祐, 鈴木 繁紀, 政井 恭兵, 加勢田 馨, 紅林 泰

  肺癌, 

  2026.04

  , 

  (NPO)日本肺癌学会

• 上行大動脈の一時離断により完全切除しえた中縦隔傍神経節細胞腫の1例

  杉野 功祐, 鈴木 繁紀, 橋詰 賢一, 寄森 駿, 鈴木 嵩弘, 大久保 祐, 灰田 周史, 政井 恭兵, 加勢田 馨, 志水 秀行, 朝倉 啓介

  日本胸部外科学会関東甲信越地方会要旨集, 

  2026.03

  , 

  日本胸部外科学会-関東甲信越地方会

• 左房内を占拠する類上皮血管内皮腫に対し、心房の立体的再建を行い完全切除した1例

  矢野 海斗, 朝倉 啓介, 伊藤 努, 中込 貴博, 鈴木 嵩弘, 大久保 祐, 鈴木 繁紀, 政井 恭兵, 加勢田 馨, 紅林 泰, 橋詰 賢一, 志水 秀行

  日本胸部外科学会関東甲信越地方会要旨集, 

  2026.03

  , 

  日本胸部外科学会-関東甲信越地方会

• 根治的サルベージ手術の適応と成績　当施設における薬物療法後のサルベージ手術の治療成績と適応

  鈴木 繁紀, 鈴木 嵩弘, 大久保 祐, 政井 恭兵, 加勢田 馨, 澤藤 誠, 塙 龍太郎, 坂巻 寛之, 朝倉 啓介

  肺癌, 

  2025.11

  , 

  (NPO)日本肺癌学会

• 患者由来肺癌オルガノイドライブラリにより見出したEGFRチロシンキナーゼ阻害薬に対する新たな耐性機序

  浜本 純子, 篠崎 太郎, 高岡 初誉, 茂松 梨咲, 伊藤 史麿, 額賀 重成, 谷 哲夫, 寺井 秀樹, 池村 辰之介, 副島 研造, 菱田 智之, 朝倉 啓介, 淺村 尚生, 福永 興壱, 佐藤 俊朗, 安田 浩之

  肺癌, 

  2025.11

  , 

  (NPO)日本肺癌学会

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Research Projects of Competitive Funds, etc. 【 Display / hide 】

Research Projects of Competitive Funds, etc. 【 Display / hide 】

• 末梢肺悪性腫瘍に対するフレキシブル凍結プローブを用いた凍結融解壊死療法

  2025.04

  -

  2028.03

  Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Research grant, No Setting

  　View Summary

  肺悪性腫瘍に冷却ガスが通じる専用の凍結端子(プローブ)を刺入して凍結させる凍結融解壊死療法があり、現在、CTガイド下に経皮的に施行し良好な局所制御率を得ている。しかしながら胸壁と胸膜を貫いてプローブを刺入するため、血気胸、播種、空気塞栓などの危険性がある。本研究グループは凍結療法を気管支鏡を用い経気管支的に行うことで合併症が回避でき、より低侵襲となることを初めて提唱した。複数の病変に繰り返し治療でき多発病変の治療にも適している。本研究では肺悪性腫瘍に対する気管支鏡を用いた経気管支的凍結融解壊死療法の有効性と安全性を動物モデルで検証すると共に、気管支鏡専用凍結プローブの開発と手技の確立を行う。

• Construction of a classification system for pectus excavatum morphology based on image data analysis and development of a new surgical support system

  2021.04

  -

  2024.03

  Grants-in-Aid for Scientific Research, Kyohei Masai, Grant-in-Aid for Scientific Research (C), Research grant, No Setting

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  The Nuss procedure, which corrects the chest wall using a titanium bar, is commonly utilized for surgical treatment of pectus excavatum. The varied form of pectus excavatum among patients underscores the importance of understanding its characteristics for effective surgical intervention.
  Factors such as the degree and asymmetry of the depression, as well as bone sclerosis associated with age, contribute to the complexity of pectus excavatum surgery. Through objective analysis of pectus excavatum morphology via image analysis, we have identified challenges with the Nuss procedure. As a result, we have developed a new surgical approach, the Combined Ravitch and Nuss Procedure (CRN procedure), which integrates the Nuss and Ravitch procedures as an innovative treatment method ready for clinical practice.

• The cytostatic effects of zoledronic acid on ACC-MESO-1 cells

  2014.04

  -

  2017.03

  MEXT,JSPS, Grant-in-Aid for Scientific Research, Asakura Keisuke, Grant-in-Aid for Scientific Research (C), Research grant, Principal investigator

  　View Summary

  Malignant pleural mesothelioma is widely resistant to therapies, and new treatment starategies are needed. We clarified that zoledronic acid reduces cell viavility and cell migration of human malignant pleural mesothelioma cells in vitro, and that induction of autophagic changes may at least in part be involved in this process.

• Anti-tumor effects of autophagy induction in malignant pleural mesothelioma.

  2010

  -

  2011

  Grants-in-Aid for Scientific Research, ASAKURA Keisuke, Grant-in-Aid for Young Scientists (B), Research grant, No Setting

  　View Summary

  Malignant pleural mesothelioma is widely resistant to therapies, and new treatment starategies are needed. Recent reports have indicated the potential efficacy of statins against malignant pleural mesothelioma cells in vitro. Here we show that lovastatin reduces primary tumor and metastasis in a mouse model of human malignant pleural mesothelioma, and that induction of autophagic changes may at least in part be involved in this process.

• Computed Simulation System for Cryoablation Therapy of Lung Tumor

  2009

  -

  2011

  Grants-in-Aid for Scientific Research, KAWAMURA Masafumi, IZUMI Yotaro, ASAKURA Keisuke, YAMAUTI Yosikane, HASHIMOTO Kohei, Grant-in-Aid for Scientific Research (C), Research grant, No Setting

  　View Summary

  With thermal monitoring of porcine lung treated by cryoablation, sequential spread of low temperature zone around cryoprobe in the porcine lung could be imaged theoretically. Then correlation between CT findings and pathological feature after lung cryoablation and low temperature zone(less than-20℃) during cryoablation was evaluated. These data should make possible to construct computed simulation system for optimal insertion of cryoprobe in the lung.

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Courses Taught 【 Display / hide 】

Courses Taught 【 Display / hide 】

• CLINICAL CLERKSHIP IN THORACIC SURGERY

  2026

• ADVANCED SURGERY

  2026

• CLINICAL ONCOLOGY

  2026

• LECTURE SERIES, SURGERY

  2026

• SURGERY

  2026

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