論文 - 南宮　湖

肺非結核性抗酸菌症の薬物療法

南宮湖， 長谷川直樹

呼吸器内科= Respiratory medicine/呼吸器内科編集委員会 編 27 (1), 37-42 2015年

Comparison of the immunogenicity and safety of polysaccharide and protein-conjugated pneumococcal vaccines among the elderly aged 80 years or older in Japan: an open-labeled …

H Namkoong, Y Funatsu, K Oishi, Y Akeda, R Hiraoka, K Takeshita, ...

Vaccine 33 (2), 327-332 2015年

Clarithromycin Expands CD11b+ Gr-1+ Cells To Ameliorate Post-Influenza Pneumococcal Pneumonia

H Namkoong, M Ishii, H Fujii, K Yagi, T Asakura, S Suzuki, T Kamo, ...

B106. HOST PATHOGEN INTERACTIONS I, A3800-A3800 2015年

Cerebrospinal fluid dynamics at the lumbosacral level in patients with spinal stenosis

K Kim, DJ Kim, KD Kim, HJ Lee, CH Sohn, SG Chung, SW Chun, ...

Fluids and Barriers of the CNS 12 (1), 1-2 2015年

C105 NONTUBERCULOUS MYCOBACTERIA EPIDEMIOLOGY: Nationwide Survey On The Epidemiology Of Pulmonary Nontuberculous Mycobacterial In Japan

H Namkoong, A Kurashima, K Morimoto, Y Hoshino, N Hasegawa, ...

American Journal of Respiratory and Critical Care Medicine 191, 1 2015年

B106 HOST PATHOGEN INTERACTIONS I: Clarithromycin Expands Cd11b+ gr-1+ cells To Ameliorate Post-Influenza Pneumococcal Pneumonia

H Namkoong, M Ishii, H Fujii, K Yagi, T Asakura, S Suzuki, T Kamo, ...

American Journal of Respiratory and Critical Care Medicine 191, 1 2015年

A56 (PATHO)-PHYSIOLOGY OF THE ALVEOLUS: Levels Of Soluble Receptor For Advanced Glycation End Products (srage) In Bronchoalveolar Lavage Fluid In Patients With Various Lung …

T Kamo, S Tasaka, Y Tokuda, T Asakura, S Suzuki, K Yagi, H Namkoong, ...

American Journal of Respiratory and Critical Care Medicine 191, 1 2015年

A32 MICROBIAL INTERACTIONS AND HOST DEFENSE: The Critical Roles Of Tumor Necrosis Factor [alpha]-Converting Enzyme During Influenza Virus And Streptococcus Pneumoniae Infection …

S Suzuki, M Ishii, H Namkoong, K Yagi, T Asakura, S Tasaka, T Kamo, ...

American Journal of Respiratory and Critical Care Medicine 191, 1 2015年

A21 GENETIC REGULATION OF CHRONIC AIRWAY INFLAMMATION: Role Of Histone Acetylation In Mice Coinfected With Influenza Virus And Streptococcus Pneumoniae

K Yagi, M Ishii, H Namkoong, T Asami, T Asakura, S Suzuki, H Fujiwara, ...

American Journal of Respiratory and Critical Care Medicine 191, 1 2015年

A case of disseminated cryptococcal infection and concurrent lung tuberculosis in a patient under steroid therapy for interstitial pneumonia

A Kuroda, S Tasaka, K Yagi, T Mochimaru, T Tani, H Namkoong, ...

Case Reports in Pulmonology 2015 2015   358926 - 358926 2015年

査読有り

　概要を見る

Both disseminated cryptococcal infection and tuberculosis occur in hosts with impaired cell-mediated immunity, but there have been few reports about the concurrent infections in patients without human immunodeficiency virus infection. A 64-year-old man, who had been taking corticosteroids for interstitial pneumonia, was diagnosed with disseminated cryptococcal infection. While the patient was receiving anticryptococcal therapy, pulmonary tuberculosis also emerged. The patient developed acute exacerbation of interstitial pneumonia and passed away. Based on the patient's clinical course, serial computed tomography images, and autopsy results, we believe that the preceding several months of corticosteroid treatment might have contributed to these coinfections in the lungs already vulnerable due to underlying fibrosis.

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D108 DIAGNOSIS AND MANAGEMENT OF NONTUBERCULOUS MYCOBACTERIA INFECTIONS: Health-Related Quality Of Life In 235 Patients With Mycobacterium Avium Complex Lung Disease In Japan

T Asakura, M Ishii, Y Funatsu, K Yagi, H Namkoong, S Suzuki, T Kamo, ...

American Journal of Respiratory and Critical Care Medicine 191, 1 2015年

Levels of soluble receptor for advanced glycation end products in bronchoalveolar lavage fluid in patients with various inflammatory lung diseases

T Kamo, S Tasaka, Y Tokuda, S Suzuki, T Asakura, K Yagi, H Namkoong, ...

Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine … 9 （ Suppl 1 ） 147 - 54 2015年

査読有り

　概要を見る

Receptor for advanced glycation end products (RAGE) is a multiligand receptor of S100/calgranulins, high-mobility group box 1, and others, and it is associated with the pathogenesis of various inflammatory and circulatory diseases. The soluble form of RAGE (sRAGE) is a decoy receptor and competitively inhibits membrane-bound RAGE activation. In this study, we measured sRAGE levels in bronchoalveolar lavage fluid (BALF) of 78 patients, including 41 with interstitial pneumonia, 11 with sarcoidosis, 9 with respiratory infection, 7 with ARDS, 5 with lung cancer, and 5 with vasculitis. Among them, sRAGE was detectable in BALF of 73 patients (94%). In patients with ARDS and vasculitis, the sRAGE levels were significantly higher than in the control subjects and those with interstitial pneumonia. The sRAGE levels were positively correlated with total cell counts in BALF and serum levels of surfactant protein-D, lactate dehydrogenase, and C-reactive protein. There was an inverse correlation between PaO2/FIO2 ratio and sRAGE levels. These results indicate that sRAGE in BALF might be considered as a biomarker of lung inflammatory disorders, especially ARDS and vasculitis.

• Access to Document (DOI)

Levels Of Soluble Receptor For Advanced Glycation End Products (srage) In Bronchoalveolar Lavage Fluid In Patients With Various Lung Diseases

T Kamo, S Tasaka, Y Tokuda, T Asakura, S Suzuki, K Yagi, H Namkoong, ...

A56.(PATHO)-PHYSIOLOGY OF THE ALVEOLUS, A2051-A2051 2015年

Immune reconstitution inflammatory syndrome due to Mycobacterium. 18F-fluorodeoxyglucose positron emission tomography-computed tomography in a patient …

H Namkoong, H Fujiwara, M Ishii, K Yagi, M Haraguchi, M Matsusaka, ...

BMC Medical Imaging 15 (1) 2015年

Immune reconstitution inflammatory syndrome due to Mycobacterium avium complex successfully followed up using 18 F-fluorodeoxyglucose positron emission tomography-computed …

H Namkoong, H Fujiwara, M Ishii, K Yagi, M Haraguchi, M Matsusaka, ...

BMC medical imaging 15 (1), 1-6 2015年

Health-Related Quality Of Life In 235 Patients With Mycobacterium Avium Complex Lung Disease In Japan

T Asakura, M Ishii, Y Funatsu, K Yagi, H Namkoong, S Suzuki, T Kamo, ...

D108. DIAGNOSIS AND MANAGEMENT OF NONTUBERCULOUS MYCOBACTERIA INFECTIONS … 2015年

Drug therapy for pulmonary nontuberculous mycobacterial disease

H Namkoong, N Hasegawa

Japanese Journal of Chest Diseases 74 (10), 1084-1094 2015年

Nationwide Survey on the Epidemiology of Pulmonary Nontuberculous Mycobacterial in Japan

H Namkoong, A Kurashima, K Morimoto, Y Hoshino, N Hasegawa, ...

C105. NONTUBERCULOUS MYCOBACTERIA EPIDEMIOLOGY, A5268-A5268 2015年

綜説 高齢者に対する肺炎球菌感染症予防戦略-23 価肺炎球菌多糖体ワクチンと 13 価肺炎球菌結合型ワクチン

南宮湖， 長谷川直樹

呼吸と循環 63 (8), 754-761 2015年

The Critical Roles Of Tumor Necrosis Factor α-Converting Enzyme During Influenza Virus And Streptococcus Pneumoniae Infection In Vivo And In Vitro

S Suzuki, M Ishii, H Namkoong, K Yagi, T Asakura, S Tasaka, T Kamo, ...

A32. MICROBIAL INTERACTIONS AND HOST DEFENSE, A1297-A1297 2015年