Matsumoto, Minako

写真a

Affiliation

School of Medicine, Department of Preventive Medicine and Public Health （Shinanomachi）

Position

Instructor
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Career 【 Display / hide 】

  • 2014.04
    -
    2016.03

    Faculty of pharmacy, 付属薬局, 薬剤師

  • 2018.04
    -
    2019.04

    医学部, 衛生学公衆衛生学教室, 特任助教

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Academic Background 【 Display / hide 】

  • 2008.04
    -
    2014.03

    Keio University, 薬学部, 薬学科

    日本, University, Graduated

  • 2016.04
    -
    2018.03

    Keio University, 健康マネジメント研究科, スポーツマネジメント専修

    日本, Graduate School, Graduated, Master's course

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Academic Degrees 【 Display / hide 】

  • 修士, Keio University, Coursework, 2018.03

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Licenses and Qualifications 【 Display / hide 】

  • 薬剤師免許, 2014.03

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Research Areas 【 Display / hide 】

  • Hygiene and public health

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Research Keywords 【 Display / hide 】

  • メタボロミクス　予防医学　公衆衛生

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Papers 【 Display / hide 】

  • Association between dyslipidemia and plasma levels of branched-chain amino acids in the Japanese population without diabetes mellitus

    Fukushima K., Harada S., Takeuchi A., Kurihara A., Iida M., Fukai K., Kuwabara K., Kato S., Matsumoto M., Hirata A., Akiyama M., Tomita M., Hirayama A., Sato A., Suzuki C., Sugimoto M., Soga T., Sugiyama D., Okamura T., Takebayashi T.

    Journal of Clinical Lipidology （Journal of Clinical Lipidology)   2019

    ISSN  19332874

    　View Summary

    © 2019 National Lipid Association Background: Branched-chain amino acids (BCAAs) play a key role in energy homeostasis. Objective: We aimed to investigate the association between plasma BCAA levels and dyslipidemia in the Japanese population without diabetes mellitus. Methods: This cross-sectional study included 4952 participants without diabetes mellitus, enrolled in the Tsuruoka Metabolomic Cohort Study. Plasma BCAA levels were measured by capillary electrophoresis–mass spectrometry. Correlations between lipid and BCAA profiles were evaluated by sex-stratified multiple linear regression analyses, after adjusting for confounders. Logistic regression was used to identify associations between BCAAs and metabolic dyslipidemia (MD) defined as triglyceride levels ≥150 mg/dL, high-density lipoprotein cholesterol levels ≤40 mg/dL for men and ≤50 mg/dL for women, or low-density lipoprotein cholesterol (LDL-C) levels ≥140 mg/dL. Results: In both sexes, the levels of individual BCAAs and the total BCAA levels correlated positively with triglyceride levels and negatively with high-density lipoprotein cholesterol levels. Valine, leucine, and total BCAA levels were weakly and positively correlated with LDL-C levels. Increased BCAA levels showed positive associations with MD. However, associations between BCAAs and elevated LDL-C levels were unclear. Furthermore, the associations between BCAA levels and MD regardless of fasting blood sugar (FBS) levels (high or low). Although valine, leucine, and total BCAA levels were weakly associated with elevated LDL-C levels in the high-FBS group, no such association was observed in the low-FBS group. Conclusions: BCAAs might be associated with MD independently of the FBS level and might play an important role in lipid metabolism and dyslipidemia.

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Presentations 【 Display / hide 】

  • 脂質異常症治療薬使用の糖尿病発症リスクに関するメタボローム疫学研究　

    2019.01, Poster (general)

  • 男性勤労者におけるストレス対処パターンと血圧値との関連の時間断面研究

    2017.10, Poster (general)

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Research Projects of Competitive Funds, etc. 【 Display / hide 】

  • スタチン使用による糖尿病発症リスクに関するメタボローム疫学研究

    2019.04
    -
    2020.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 松元　美奈子, Grant-in-Aid for Research Activity Start-up , Principal Investigator

  • スタチン使用による糖尿病発症リスクに関するメタボローム疫学研究

    2018.10
    -
    Present

    Research grant, Principal Investigator

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Social Activities 【 Display / hide 】

  • 鶴岡みらい健康づくり活動

    2017
    -
    Present
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Memberships in Academic Societies 【 Display / hide 】

  • 日本産業衛生学会, 

    2018.04
    -
    Present

  • 日本薬剤疫学会, 

    2018
    -
    Present

  • 日本循環器予防学会, 

    2018
    -
    Present

  • 日本動脈硬化学会, 

    2018
    -
    Present

  • 日本疫学会, 

    2018
    -
    Present

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