Okamura, Tomonori



School of Medicine, Department of Preventive Medicine and Public Health (Shinanomachi)



E-mail Address

E-mail address

External Links

Career 【 Display / hide

  • 1988.04

    Ministry of Health and Welfare, Japan

  • 1988.04

    Kochi Prefectural Tosayamada Health Center

  • 1993.04

    Osaka Medical Center for Cancer and Cardiovascular Diseases

  • 2000.03

    Associate Professor, Department of Health Science, Shiga University of Medical Science

  • 2002.10

    Department of Epidemiology and Public Health, Imperial College

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Academic Background 【 Display / hide

  • 1988.03

    University of Tsukuba, School of Medicine

    University, Graduated

Academic Degrees 【 Display / hide

  • MD,PhD, University of Tsukuba, Dissertation, 1996.02

Licenses and Qualifications 【 Display / hide

  • 医師免許, 1988.05

  • 日本医師会認定産業医, 1998.09

  • 介護支援専門員, 2001.03

  • 日本公衆衛生学会認定専門家, 2011.03

  • 社会医学系指導医, 2017.03


Research Areas 【 Display / hide

  • Epidemiology and preventive medicine

  • Public Hygiene Studies/Health Science

Research Keywords 【 Display / hide

  • Preventive Medicine

  • Epidemiology and Public health

  • Dyslipidemia

  • Health Promotion

  • cardiovascular disease

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Books 【 Display / hide

  • In: Vasan R., Sawyer, D.(eds.) The Encyclopedia of Cardiovascular Research and Medicine, vol.[3]

    Okamura T, Sugiyama D, Hirata T, Kuwabara K and Hirata A., Elsevier, 2018,  Page: .

    Scope: Lipids and Cardiovascular Diseases: Epidemiologic Perspectives.,  Contact page: 221-229

  • 第三期特定健診・特定保健指導ガイド(門脇 孝、津下一代 編)

    Okamura Tomonori, 南山堂、東京, 2018.09

    Scope: 冠動脈疾患(虚血性心疾患)発症予防からみた脂質管理.pp119-127

  • 動脈硬化性疾患予防のための脂質異常症治療ガイド2018年版

    Okamura Tomonori, (社)日本動脈硬化学会、東京, 2018

  • 岸玲子監修、小泉昭夫、馬場園明、今中雄一、武林亨編.NEW予防医学・公衆衛生学.

    Okamura Tomonori, 南江堂、東京, 2018

    Scope: 第2章.疫学と方法, pp64-80

  • 寺本民生、木庭新治、本田佳子、朝倉比都美編:脂質異常症の最新食事療法のなぜに答える. 栄養指導・管理のためのスキルアップシリーズ Vol 5(臨床栄養別冊)

    岡村智教. , 医歯薬出版株式会社, 2017

    Scope: これはどのような意味をもちますか?.脂質異常症の有病者数の推移について教えてください.,  Contact page: 7-11

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Papers 【 Display / hide

  • Higher serum uric acid level is inversely associated with renal function assessed by cystatin C in a Japanese general population without chronic kidney disease: The KOBE study

    Kubo S., Nishida Y., Kubota Y., Higashiyama A., Sugiyama D., Hirata T., Miyamatsu N., Tanabe A., Hirata A., Tatsumi Y., Kadota A., Kuwabara K., Nishikawa T., Miyamoto Y., Okamura T.

    BMC Nephrology (BMC Nephrology)  20 ( 1 )  2019.04

     View Summary

    © 2019 The Author(s). Background: Although several epidemiological studies have suggested that high serum uric acid (SUA) levels are related to a decline in kidney function, only a few studies have investigated using cystatin C to calculate estimated glomerular filtration rate (eGFR). We aimed to clarify the relationship between SUA levels and kidney function assessed by cystatin C in a Japanese general community population without chronic kidney disease (CKD). Methods: We conducted a community-based cross-sectional study that included 1086 healthy participants, aged 40-74 years, without CKD and not undergoing treatment of hyperuricemia, who had participated in the baseline survey of the Kobe Orthopedic and Biomedical Epidemiological (KOBE) study. The preconditions for participation in this study were no past histories of cardiovascular disease or cancer, and not undergoing treatment for diabetes, hypertension, or dyslipidemia. We classified the participants into quartiles stratified by sex according to their SUA level and then examined the relationship with eGFR. The odds ratios for having a low eGFR, defined as the lowest quartile of eGFR (i.e., ≤78.4 mL/min/1. 73m 2 ) was estimated according to SUA quartiles (men, Q1 ≤ 5.0, Q2 5.1-5.9, Q3 6.0-6.6, and Q4 ≥ 6.7; women, Q1 ≤ 3.8, Q2 3.9-4.3, Q3 4.4-4.9, and Q4 ≥ 5.0 mg/dL) after adjustment for age, body mass index, systolic blood pressure, HbA1c, high and low density lipoprotein cholesterol, and smoking and drinking habits. The adjusted mean of each quartile was also calculated. Results: Multivariable-adjusted means of eGFR showed a graded decrease in higher SUA quartiles (men, Q1 90.5, Q2 88.0, Q3 83.5, and Q4 82.0; women, Q1 95.7, Q2 91.3, Q3 89.2, and Q4 86.7). In addition, the multivariable-adjusted odds ratios for having a lower eGFR (95% confidence interval) for each SUA quartile compared with Q1 was Q2 2.29 (0.98, 5.35), Q3 4.94 (2.04, 11.97), and Q4 8.01 (3.20, 20.04) for men, and was Q2 2.20 (1.12, 4.32), Q3 2.68 (1.39, 5.20), and Q4 4.96 (2.62, 9.41) for women. Conclusions: There was a graded inverse relationship between mild elevations in SUA levels and eGFR assessed by cystatin C in an apparently healthy Japanese population without CKD. This association was similar in both men and women.

  • Associations of Overweight, Obesity, and Underweight With High Serum Total Cholesterol Level Over 30 Years Among the Japanese Elderly: NIPPON DATA 80, 90, and 2010

    Shibata Yosuke, Ojima Toshiyuki, Nakamura Mieko, Kuwabara Kazuyo, Miyagawa Naoko, Saito Yoshino, Nakamura Yasuyuki, Kiyohara Yutaka, Nakagawa Hideaki, Fujiyoshi Akira, Kadota Aya, Ohkubo Takayoshi, Okamura Tomonori, Ueshima Hirotsugu, Okayama Akira, Miura Katsuyuki, Ueshima Hirotsugu, Miura Katsuyuki, Okayama Akira, Okamura Tomonori, Okayama Akira, Okamura Tomonori, Ueshima Hirotsugu, Okayama Akira, Okamura Tomonori, Saitoh Shigeyuki, Sakata Kiyomi, Hozawa Atsushi, Hayakawa Takehito, Nakamura Yosikazu, Nishi Nobuo, Okuda Nagako, Okamura Tomonori, Murakami Yoshitaka, Ohkubo Takayoshi, Kasagi Fumiyoshi, Izumi Toru, Matsumura Yasuhiro, Ojima Toshiyuki, Tamakoshi Koji, Nakagawa Hideaki, Kita Yoshikuni, Miura Katsuyuki, Kadota Aya, Miyamatsu Naomi, Nakamura Yasuyuki, Yoshita Katsushi, Miyamoto Yoshihiro, Kodama Kazunori, Kiyohara Yutaka

    JOURNAL OF EPIDEMIOLOGY 29 ( 4 ) 133 - 138 2019.04

    Research paper (scientific journal),  ISSN  0917-5040

  • One-year weight loss maintenance outcomes following a worksite-based weight reduction program among Japanese men with cardiovascular risk factors

    Tsukinoki R., Okamura T., Okuda N., Kadota A., Murakami Y., Yanagita M., Miyamatsu N., Miura K., Ueshima H.

    Journal of Occupational Health (Journal of Occupational Health)  61 ( 2 ) 189 - 196 2019.03

    Research paper (scientific journal),  ISSN  13419145

     View Summary

    © 2019 Japan Society for Occupational Health. Objectives: Worksite-based programs present a simple and effective approach to facilitate weight reduction in employees. Despite the importance of 1-year weight loss maintenance, studies have generally focused on the short-term effects of weight reduction programs. In addition, little is known about the long-term weight maintenance outcomes in Asian populations. We examined the long-term maintenance effects of a worksite-based weight reduction program among Japanese men with cardiovascular risk factors. Methods: The study sample comprised 58 overweight men with cardiovascular risk factors who had voluntarily participated in a randomized crossover trial involving a 3-month weight reduction program. Participants were followed up for 1 year after the trial concluded, and both groups were merged for the analysis. We compared the changes in body weight before the post-trial follow-up and after 12 months to examine the long-term maintenance effects of the program. Changes in other cardiovascular risk factors (eg, waist circumference, blood pressure, lipid measures, and diabetes-related measures) were also examined. Results: Both groups of study participants achieved weight loss during the weight reduction program. Total 53 participants (91.4%) completed the 12-month post-trial follow-up. There were no significant changes in mean body weight (mean: -0.11, 95% confidence interval: -0.7-0.49 kg) and other cardiovascular risk factors between the beginning and end of the follow-up period. Conclusions: This study showed that the worksite-based weight reduction program not only enabled short-term weight loss, but that the participants were able to successfully maintain their weight for 1 year after the program without any supplementary interventions.

  • Association of blood pressure with estimates of 24-h urinary sodium and potassium excretion from repeated single-spot urine samples

    Trang Thi Minh Nguyen, Miura Katsuyuki, Tanaka-Mizuno Sachiko, Tanaka Taichiro, Nakamura Yasuyuki, Fujiyoshi Akira, Kadota Aya, Tamaki Junko, Takebayashi Toru, Okamura Tomonori, Ueshima Hirotsugu

    HYPERTENSION RESEARCH 42 ( 3 ) 411 - 418 2019.03

    Research paper (scientific journal),  ISSN  0916-9636

  • Impact of Hypertension on Hospitalizations for Cardiovascular Diseases in a Worksite Population: An Epidemiologic Study Using Claims Data for Workers

    Fukushima Ayako, Khabtheni Wafa, Guelfucci Florent, Onishi Yoshie, Sugiyama Daisuke, Okamura Tomonori, Toumi Mondher

    AMERICAN JOURNAL OF HYPERTENSION 32 ( 3 ) 298 - 307 2019.03

    Research paper (scientific journal),  ISSN  0895-7061

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Papers, etc., Registered in KOARA 【 Display / hide

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Reviews, Commentaries, etc. 【 Display / hide

  • 日本における脂質と動脈硬化性疾患の関連-疫学研究のエビデンス-.


    Medical Practice  36 ( 1 ) 40 - 44 2019

    Introduction and explanation (scientific journal), Joint Work

  • 脂質異常症のスクリーニングとリスク評価.


    臨床と研究 96 ( 1 ) 6 - 11 2019

    Introduction and explanation (scientific journal), Joint Work

  • 高HDL血症と心血管イベントに関する疫学研究からの知見-日常診療で高HDL血症をみつけたらどうするか.


    医学のあゆみ  268 ( 5 ) 415 - 419 2019

    Introduction and explanation (scientific journal), Single Work

  • 塩味味覚感度の低さは仮面高血圧に関連する:神戸研究


    血圧 26 ( 5 ) 248 - 249 2019

    Introduction and explanation (scientific journal), Joint Work

  • 糖尿病と腎臓病の重症化予防事業-循環器疾患との関連を中心に-


    日本栄養士会雑誌 62 ( 3 ) 14 - 17 2019

    Introduction and explanation (scientific journal), Single Work

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Presentations 【 Display / hide

  • 循環器疾患の絶対リスクの予測とその臨床応用


    第55回循環器病予防学会/第8回臨床高血圧フォーラム, 2019.05, Symposium, Workshop, Panelist (nomination)

  • 脳卒中と循環器疾患克服5カ年計画は達成可能か:0次予防から3次予防まで. Prevention Strategies for Cardiovascular Diseases in Japanese Population


    第83回日本循環器学会学術集会, 2019.03, Symposium, Workshop, Panelist (nomination)

  • 動脈硬化性疾患予防のための包括的な危険因子の管理


    第19回動脈硬化教育フォーラム, 2019.02, Public discourse, seminar, tutorial, course, lecture and others

  • 診療ガイドラインへの疫学研究の活用-JASガイドライン2012と2017から


    第29回日本疫学会学術総会 , 2019.02, Symposium, Workshop, Panelist (nomination)

  • EPOCH-JAPAN研究:健康日本21や診療ガイドラインへのエビデンス提供を目指した共同プロジェクト


    学会連携ワークショップ「出生コホート研究連携ワークショップ」 (東京) , 2019.01, Oral Presentation(guest/special),  日本DOHaD学会

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Research Projects of Competitive Funds, etc. 【 Display / hide

  • 厚生労働科学研究費補助金(循環器疾患・糖尿病等生活習慣病対策政策研究事業生涯にわたる循環器疾患の個人リスクおよび集団のリスク評価ツールの開発を目的とした大規模コホート統合研究(H29-循環器等-一般-003):


    厚生労働省, 岡村 智教, Research grant

  • 脂質異常症の質的な評価と動脈硬化性疾患の関連についての地域疫学研究(研究代表者 岡村智教:基盤研究B 16H05249)


    Research grant, Principal Investigator

  • 循環器疾患における集団間の健康格差の実態把握とその対策を目的とした大規模コホート共同研究(研究代表者 岡村智教:厚生労働科学研究 H26-循環器等(生習)-一般​-001)


    岡村 智教, Research grant

  • 酸化LDLコレステロールと潜在性動脈硬化症、生活機能の関連についての地域疫学研究(研究代表者 岡村智教:基盤研究B 23390178)


    岡村 智教, Research grant

  • 大規模コホート共同研究の発展による危険因子管理の優先順位の把握と個人リスク評価に関するエピデンスの構築(研究代表者 岡村智教:厚生労働科学研究 H23-循環器等(生習)-一般-005)


    岡村 智教, Research grant

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Works 【 Display / hide

  • 生活習慣病予防のエビデンス(全24回)

    Okamura Tomonori


    Other, Single

Awards 【 Display / hide

  • 日本動脈硬化学会五島雄一郎賞

    Okamura Tomonori, 2013.07, 日本動脈硬化学会, A series of community-based cohort studies concerning the relationship between dyslipidemia and cardiovascular disease in Japanese populations

    Type of Award: Awards of National Conference, Council and Symposium

  • 日本疫学会奨励賞

    Okamura Tomonori, 2009.01, 日本疫学会, 日本人を対象とした脂質異常症の疫学研究

    Type of Award: Awards of National Conference, Council and Symposium

  • 日本公衆衛生学会奨励賞

    Okamura Tomonori, 2002.10, 日本公衆衛生学会, 老人保健事業を中心とした地域保健対策の評価と推進に関する研究

    Type of Award: Awards of National Conference, Council and Symposium

  • 厚生統計研究奨励賞

    Okamura Tomonori, 1998.12, 厚生統計協会, 循環器検診所見と高齢者(65~74歳)の生命予後、活動能力の関連についての追跡研究

    Type of Award: Awards of Publisher, Newspaper Company and Foundation

Other 【 Display / hide

  •  View Details

    先端医療センターコホート研究チーム チームリーダー

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    国立循環器病研究センター 客員部長

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    滋賀医科大学 客員教授


Courses Taught 【 Display / hide











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Courses Previously Taught 【 Display / hide

  • Public Health

    Keio University, 2018, Autumn Semester, Major subject, Lecture, Within own faculty, 110people

  • 公衆衛生学

    Keio University, 2015, Autumn Semester, Major subject, Lecture, Within own faculty

  • 公衆衛生学

    Keio University, 2014, Autumn Semester, Major subject, Lecture, Within own faculty

  • 公衆衛生学

    Keio University, 2013, Autumn Semester, Major subject, Lecture, Within own faculty

  • 公衆衛生学

    Keio University, 2012, Autumn Semester, Major subject, Lecture, Within own faculty

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Social Activities 【 Display / hide

  • 全国健康保険協会 理事(保健担当)

  • 健康保険組合連合会 データヘルス計画推進会議委員


Memberships in Academic Societies 【 Display / hide

  • Japan Atherosclerosis Society

  • Japan Epidemiological Association

  • Japanese Medical Society of Alcohol and Drug Studies

  • The Japanese Association for Cerebro-cardiovascular Disease Control(JACD)

  • Japanese Society of Public Health


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Committee Experiences 【 Display / hide

  • 2011.05

    医師試験委員, 厚生労働省

  • 2011.11

    厚生科学審議会専門委員(次期国民健康づくり運動プラン策定専門委員会), 厚生労働省

  • 2013.04

    国民健康・栄養調査企画解析検討会 構成員, 厚生労働省

  • 2013.06

    日本人の長寿を支える「健康な食事」のあり方に関する検討会 構成員, 厚生労働省

  • 2014.07

    厚生科学審議会専門委員(健康日本21(第二次)推進専門委員会), 厚生労働省

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