Yasui, Masato

写真a

Affiliation

School of Medicine, Department of Pharmacology (Shinanomachi)

Position

Professor

E-mail Address

E-mail address

Related Websites

Profile 【 Display / hide

  • ◆Education 1989 Medical License (M.D.), Graduated from School of Medicine, Keio University (Tokyo, Japan) 1997 Doctor of Philosophy (Ph. D.) at the Karolinska Institute (Stockholm, Sweden). Thesis Title: Expression and Regulation of water channels and ion transpoters (Ontogenic Aspects) 1998 Doctor of Medical Science (Ph.D.) at School of Medicine, Keio University (Tokyo, Japan) ◆Clinical Training 1989-1992 Clinical Resident of Pediatrics St. Luke’s International Hospital, Tokyo, Japan 1992 Clinical Fellow of Neonatolgy Tokyo Women’s Medical University, Tokyo, Japan ◆Research Training 1992 Guest Researcher, Dept. of Molecular Neurobiology, University of Tokyo, Tokyo, Japan (Prof. Katsuhiko Mikoshiba) 1993-1997 Postgraduate Student, Dept of Woman and Child Health, Pediatric Unit, Karolinska Institute, Stockholm, Sweden (Prof. Anita Aperia) 1997-2000 Postdoctoral Research Fellow, Dept. of Biological Chemistry Johns Hopkins Univ. School of Medicine, Baltimore, USA (Prof. Peter Agre) ◆Academic Positions 2000-2001 Instructor, Dept. of Biol. Chem., Johns Hopkins School of Medicine, Baltimore, Maryland, USA 2001- Assistant Professor, Depts of Pediatrics and Biological Chemistry, Johns Hopkins School of Medicine, Baltimore, Maryland, USA 2004-2006 Visiting Professor, Tokyo Dental College, Chiba. Japan 2006- Professor and Chair, Department of Pharmacology Keio University School of Medicine, Tokyo Japan Academic Positions 2000-2001 Instructor, Dept. of Biol. Chem., Johns Hopkins School of Medicine, Baltimore, Maryland, USA 2001- Assistant Professor, Depts of Pediatrics and Biological Chemistry, Johns Hopkins School of Medicine, Baltimore, Maryland, USA 2004-2006 Visiting Professor, Tokyo Dental College, Chiba. Japan 2006- Professor and Chair, Department of Pharmacology, Keio University School of Medicine, Tokyo Japan

Other Affiliation 【 Display / hide

  • School of Medicine, Professor

Career 【 Display / hide

  • 1989.04
    -
    1992.03

    St. Luke’s International Hospital, Pediatrics, Clinical Resident

  • 1992.04
    -
    1993.01

    Tokyo Women’s Medical University, Neonatolgy, Clinical Fellow

  • 1992.04
    -
    1993.01

    University of Tokyo, Dept. of Molecular Neurobiology, Guest Researcher

  • 2000
    -
    2001

    Johns Hopkins School of Medicine, Instructor

  • 2001
    -
    2006

    Johns Hopkins School of Medicine, USA, Depts of Pediatrics and Biological Chemistry, Assistant Professor

display all >>

Academic Background 【 Display / hide

  • 1983.04
    -
    1989.03

    Keio University, School of Medicine

    Japan, University, Graduated

  • 1997.04

    the Karolinska Institute (Stockholm, Sweden), Doctor of Philosophy (Ph. D.)

    Sweden, Graduate School, Graduated, Doctoral course

Academic Degrees 【 Display / hide

  • Doctor of Philosophy, スウェーデン王国カロリンスカ医科大学, 1997.04

  • 博士(医学), 慶応義塾大学, 1998

 

Research Areas 【 Display / hide

  • General pharmacology

Research Keywords 【 Display / hide

  • 水・電解質・アクアポリン

Research Themes 【 Display / hide

  • ①アクアポリンの構造機能相関 ②脳のアクアポリンの機能解析 ③アクアフォトミクスの臨床応用, 

    1997.01
    -
    Present

 

Papers 【 Display / hide

  • Characterization of Intra/Extracellular Water States Probed by Ultrabroadband Multiplex Coherent Anti-Stokes Raman Scattering (CARS) Spectroscopic Imaging.

    Nuriya M, Yoneyama H, Takahashi K, Leproux P, Coudrc V, Yasui M, Kano H.

    J. Phys. Chem. A. 123 ( 17 ) 3928 - 3934 2019

  • Adrenergic Receptor Antagonism Induces Neuroprotection and Facilitates Recovery from Acute Ischemic Stroke.

    Monai H, Wang X, Yahagi K, Lou N, Mestre H, Xu Q, Abe Y, Yasui M, Iwai Y, Nedergaard M and Hirase H.

    Proc. Natl. Acad. Sci. USA. (in press)   2019

  • Quantification of anomeric structural changes of glucose solution using near-infrared spectra.

    Tanaka S, Kojic D, Tsenkova R and Yasui M.

    Carbohydr. Res. 463   40 - 46 2018

  • Comparison of diffusion-weighted MRI and anti-Stokes Raman scattering (CARS) measurements of the inter-compartmental exchange-time of water in expression-controlled aquaporin-4 cells.

    Obata T, Kershaw J, Tachibana Y, Miyauchi T, Abe Y, Shibata S, Kawaguchi H, Ikoma Y, Takuwa H, Aoki I, Yasui M.

    Sci Rep. 8 ( 1 ) 17954 2018

  • Aquaporin-4-dependent glymphatic solute transport in the rodent brain.

    Mestre H, Hablitz LM, Xavier AL, Feng W, Zou W, Pu T, Monai H, Murlidharan G, Castellanos Rivera RM, Simon MJ, Pike MM, Plá V, Du T, Kress BT, Wang X, Plog BA, Thrane AS, Lundgaard I, Abe Y, Yasui M, Thomas JH, Xiao M, Hirase H, Asokan A, Iliff JJ, Nedergaard M.

    Elife. 7 2018

display all >>

Presentations 【 Display / hide

  • Roles of aquaporin‐ 4(AQP4)in neurodegenerative diseases

    Third Annual Stanford/Kanagawa Symposium, 2018.11

  • 睡眠研究の最先端―ストレス社会で健康を守るために

    在ベルリン日本大使館慶應義塾大学医学講演会, 2018.10

  • アクアポリン4(AQP4)と神経変性疾患の病態生理

    第30回日本神経免疫学会学術集会, 2018.09

  • New Insight into Aquaporin Function as Drug Targets

    18th World Congress of Basic and Clinical Pharmacology, 2018.07

  • 脳のアクアポリンと神経変性疾患

    第30回臨床MR脳機能研究会学術集会, 2018.04

display all >>

Research Projects of Competitive Funds, etc. 【 Display / hide

  • 脳リンパ流の生理とその破綻による高次脳機能低下メカニズムの解明

    2018.04
    -
    2021.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 安井 正人, Grant-in-Aid for Scientific Research (B), Principal Investigator

  • Development of a new therapy for brain edema: study for regulation of AQP4 as a molecular target

    2015.04
    -
    2018.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 安井 正人, Grant-in-Aid for Scientific Research (B), Principal Investigator

 

Courses Taught 【 Display / hide

  • STRUCTURAL BIOLOGY: SEMINAR

    2021

  • STRUCTURAL BIOLOGY: PRACTICE

    2021

  • PHARMACOLOGY: SEMINAR

    2021

  • PHARMACOLOGY: PRACTICE

    2021

  • PHARMACOLOGY

    2021

display all >>

Courses Previously Taught 【 Display / hide

  • 薬理学総論・薬理学各論・薬理学実習

    Keio University, 2017

  • 薬理学総論・薬理学各論・薬理学実習

    Keio University, 2015, Spring Semester

Educational Activities and Special Notes 【 Display / hide

  • NEW薬理学

    1989.02

    , Development of Textbook and Teaching Material

 

Memberships in Academic Societies 【 Display / hide

  • 日本薬理学会・日本小児科学会・日本臨床薬理学会・日本生物物理学会