Yuzaki, Michisuke

写真a

Affiliation

School of Medicine, Department of Physiology (Shinanomachi)

Position

Professor

E-mail Address

E-mail address

Related Websites

External Links

Profile 【 Display / hide

  • 2003 - Today Professor, School of Medicine, Keio University 2002 - 2003 Associate Professor, St. Jude Children's Research Hospital 1995 - 2002 Assistant Professor, St. Jude Children's Research Hospital 1993 - 1995 HFSP long-term fellow, Roche Institute for Molecular Biology 1989 - 1993 JSPS fellow, Jichi Medical School

Career 【 Display / hide

  • 2003.04
    -
    Present

    Keio University, School of Medicine, Dept Physiology, Professor

Academic Background 【 Display / hide

  • 1985.03

    Jichi Medical University, Faculty of Medicine, 医学科

    University, Graduated

  • 1993.03

    Jichi Medical University, Graduate School, Division of Medicine, Neuroscience

    Graduate School, Completed, Doctoral course

Academic Degrees 【 Display / hide

  • 医学博士, Jichi Medical University, Coursework, 1993.03

 

Research Areas 【 Display / hide

  • Neurophysiology / General neuroscience (General Neuroscience)

Research Keywords 【 Display / hide

  • glutamate receptor

  • synaptic plasticity

  • synapse formation

  • cerebellum

Research Themes 【 Display / hide

  • Functional and morphological synaptic plasticity underlying learning and memory, 

    2003.04
    -
    Present

 

Papers 【 Display / hide

  • The C-terminal juxtamembrane region of the δ2 glutamate receptors controls its export from the endoplasmic reticulum

    'MATSUDA SHINJI, HANNEN ROSALIND, MATSUDA KEIKO, YAMADA NOBUAKI, TUBBS THOMAS, YUZAKI MICHISUKE'

    European Journal of Neuroscience 19   1683-1690 2004.02

    Research paper (scientific journal), Joint Work, Accepted

  • Specific assembly with NR3B subunit controls surface expression and calcium permeability of NMDA receptors.

    'MATSUDA KEIKO, FLETCHER MATT, KAMIYA YOSHINORI, YUZAKI MICHISUKE'

    Journal of Neuroscience  ( 23 ) 10064-10073 2003

    Research paper (scientific journal), Joint Work, Except for reviews

  • Novel role of δ2-glutamate receptors in AMPA receptor trafficking and cerebellar learning

    'HIRAI HIROKAZU, LAUNEY, THOMAS, MIKAWA SUMIKO, TORASHIMA TAKASHI, YANAGIHARA DAY, KASAURA TSUYOSHI, MIYAMOTO AKIHIRO, YUZAKI MICHISUKE'

    Nature Neuroscience  ( 6 ) 869-876 2003

    Research paper (scientific journal), Joint Work, Except for reviews

  • A hot spot for hotfoot mutations in the gene encoding δ2 glutamate receptor.

    'WANG YING, MATSUDA SHINJI, DREWS VALERIE, TORASHIMA TAKASHI, MEISLER MIRIAM H., YUZAKI MICHISUKE'

    European Journal of Neuroscience  ( 17 ) 1581-1590 2003

    Research paper (scientific journal), Joint Work, Except for reviews

  • New insights into the structure and function of glutamate receptors - The orphan receptor δ2 reveals its family’s secrets.

    YUZAKI MICHISUKE

    The Keio Journal of Medicine  ( 52 ) 92-99 2003

    Research paper (scientific journal), Single Work, Except for reviews

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Papers, etc., Registered in KOARA 【 Display / hide

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Reviews, Commentaries, etc. 【 Display / hide

  • La Dolce Vita of Neurexin: Synaptic Partnerships through Glycosaminoglycans

    Suzuki K., Yuzaki M.

    Cell (Cell)  174 ( 6 ) 1337 - 1338 2018.09

    ISSN  00928674

     View Summary

    © 2018 Elsevier Inc. Various neurexin transcripts are thought to serve as presynaptic “hub” molecules by binding to their specific synaptic partners. In this issue, Zhang et al. demonstrate that neurexins are heparan sulfate (HS) proteoglycans and that the HS modification is important for synaptic function in vitro and in vivo. These findings open up the possibility of many more binding partners for the neurexins. Various neurexin transcripts are thought to serve as presynaptic “hub” molecules by binding to their specific synaptic partners. In this issue, Zhang et al. demonstrate that neurexins are heparan sulfate (HS) proteoglycans and that the HS modification is important for synaptic function in vitro and in vivo. These findings open up the possibility of many more binding partners for the neurexins.

Presentations 【 Display / hide

  • Molecules controlling synapse structure and plasticity: Casting new light on two old molecules GluRδ2 and cerebellin

    YUZAKI MICHISUKE

    Neurobiology Seminar Program at UAB ('Birmingham, AL, USA') , 2003.03, Oral Presentation(guest/special)

  • The δ2 glutamate receptor and the Lurcher mutant: what happens when a good receptor goes bad?

    YUZAKI MICHISUKE

    Spring Brain Conference 2004 ('Senoda, AZ, USA') , 2003.03, Oral Presentation(guest/special)

Research Projects of Competitive Funds, etc. 【 Display / hide

  • Dynamic regulation of cerebellar neural circuits by "scrap and build" mechanisms

    2016.06
    -
    2021.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 柚崎 通介, Grant-in-Aid for Scientific Research on Innovative Areas, Principal Investigator

  • 補体ファミリー分子によるシナプス形成・維持・除去と可塑性制御機構の解明

    2016.04
    -
    2021.03

    Grant-in-Aid for Scientific Research, Principal Investigator

  • Bridge over troubled synapses: synthetic extracellular protein scaffolds for neuronal connectivity

    2014.06
    -
    2017.12

    Human Frontier Science Program, Research grant, Principal Investigator

  • シナプス可塑性を支える新しいAMPA受容体輸送制御機構の解明

    2011.04
    -
    2016.03

    Grant-in-Aid for Scientific Research, Research grant

  • 成熟脳におけるシナプス形成機構の解明と制御

    2009.04
    -
    2014.03

    -, Research grant, Principal Investigator

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Works 【 Display / hide

  • 学務委員会委員

    2003.10
    -
    2005.09

    Other

Awards 【 Display / hide

  • Science and Technology Award

    2012

    Type of Award: Other Awards

  • Tokizane Memorial Prize

    2012

    Type of Award: Awards of Publisher, Newspaper Company and Foundation

  • 三四会北里賞

    YUZAKI MICHISUKE, 2005

    Type of Award: Keio commendation etc.

 

Courses Taught 【 Display / hide

  • PHYSIOLOGY: SEMINAR

    2019

  • PHYSIOLOGY: PRACTICE

    2019

  • PHYSIOLOGY 1

    2019

  • PHYSIOLOGY

    2019

  • MCB(MOLECULAR CELL BIOLOGY)

    2019

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Social Activities 【 Display / hide

  • Cerebellum誌

    2006
    -
    Present
  • Frontiers in Molecular Neuroscience誌

    2008
    -
    Present
  • European Journal of Neuroscience誌

    2008
    -
    Present
  • Journal of Physiology

    2015
    -
    Present
  • Neuroscience Research

    2009
    -
    Present

Memberships in Academic Societies 【 Display / hide

  • 日本生理学会, 

    2008
    -
    Present
  • 日本生理学会, 

    2008
    -
    Present
  • 日本神経科学学会, 

    2008
    -
    Present
  • 日本神経科学学会, 

    2006
    -
    Present
  • 日本生理学会, 

    2007
    -
    2008

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Committee Experiences 【 Display / hide

  • 2008
    -
    Present

    常任幹事, 日本生理学会

  • 2008
    -
    Present

    生理学用語委員, 日本生理学会

  • 2008
    -
    Present

    理事, 日本神経科学学会

  • 2008
    -
    Present

    Director, 日本神経科学学会

  • 2006
    -
    Present

    ホームページ編集小委員会委員長, 日本神経科学学会

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