TERASAWA Yuri

写真a

Affiliation

Faculty of Letters Department of Psychology ( Hiyoshi )

Position

Professor

Related Websites

External Links

Career 【 Display / hide 】

  • 2011.04
    -
    2014.03

    National Center of Neurology and Psychiatry, Department of Psychophysiology, 研究員

  • 2014.04
    -
    2019.03

    Keio University, Department of Psychology, Faculty of Literature, Assistant Professore

  • 2019.04
    -
    2026.03

    Keio University, Department of Psychology, Associate Professor

  • 2026.04
    -
    Present

    Keio University, Department of Psychology, Professor

Academic Background 【 Display / hide 】

  • 2001.04
    -
    2005.03

    Keio University, Faculty of Literature, Department of Psychology

    University, Graduated

  • 2005.04
    -
    2007.03

    Keio University, Graduate School of Human Relations, Department of Psychology

    Graduate School, Completed, Master's course

  • 2007.04
    -
    2010.03

    Keio University, Graduate School of Human Relations, Department of Psychology

    Graduate School, Withdrawal after completion of doctoral course requirements, Doctoral course

Academic Degrees 【 Display / hide 】

  • 博士(心理学), 慶應義塾大学, Coursework, 2013.02

 

Research Areas 【 Display / hide 】

  • Humanities & Social Sciences / Experimental psychology

  • Life Science / Basic brain sciences

Research Keywords 【 Display / hide 】

  • Interoception

  • Affective neuroscience

  • emotion

  • Neuropsychology

  • Cognitive neuroscience

 

Books 【 Display / hide 】

  • The Neural Basis of Interoception

    Terasawa Y., Brewer R., Interoception A Comprehensive Guide, 2024.01

     View Summary

    The underlying neural substrates of interoception have been a topic of research interest from the conceptualisation of interoception. In fact, many of the (multiple) definitions of interoception have drawn upon our understanding of neural pathways and brain regions in order to distinguish interoception from other forms of perception, and discriminate between separate facets of interoception. In this chapter, we review early and contemporary research on the neural substrates of interoception. We describe the neural and humoral pathways from peripheral sensors in the body (chemoreceptors, humoral receptors, specialised mechanoreceptors and free nerve endings) to the brain, for example via cranial nerves and spinal visceral afferents projecting to the brainstem. We then summarise the limbic and cortical regions involved in interoception, such as the thalamus, anterior insula and anterior cingulate cortex. We also discuss recent evidence regarding the integration of interoeptive information, and interactions between afferent and efferent signals at different points throughout the interoceptive neural networks. We end the chapter with a discussion of outstanding questions and priorities for future research.

  • Neurocognitive mechanisms of social anxiety and interoception

    Terasawa Y., Umeda S., Island of Reil (Insula) in the Human Brain: Anatomical, Functional, Clinical and Surgical Aspects, 2018.07

  • Island of Reil (Insula) in the Human Brain

    TERASAWA Yuri, UMEDA Satoshi, Springer, 2018.01

    Scope: Neurocognitive Mechanisms of Social Anxiety and Interoception

  • Memory in a Social Context

    Terasawa Yuri, Umeda Satoshi, Springer, 2017.12

    Scope: The impact of interoception on memory

     View Summary

    <p>Using interoception as a keyword, this chapter has summarized how changes in the internal physical state are encoded and how the processing of interoceptive information affects the memory of episodes and events. Interoceptive information processing is discussed frequently in the context of emotion in psychology. On the other hand, research studies and literature that have examined its relation to episodic memory are rare. However, changes in the internal physical state exist at the foundation of various concepts that have examined its relationship with memory. To understand the relationship more precisely, we focused on the following issues in this chapter: emotional arousal and bodily responses; effects of bodily responses on memory encoding; judgment related to memories and bodily response; and insular cortex and memory consolidation. Throughout the chapter, we presented the possibility that change in the physical state itself plays a role in latently supporting the encoding and recollection process.</p>

Papers 【 Display / hide 】

  • Paradoxical somatic information processing for interoception and anxiety in alexithymia

    Yuri Terasawa, Kentaro Oba, Yuki Motomura, Ruri Katsunuma, Hiroki Murakami, Yoshiya Moriguchi

    European Journal of Neuroscience (Wiley)  54 ( 11 ) 8052 - 8068 2021.11

    Research paper (scientific journal), Joint Work, Accepted,  ISSN  0953816X

     View Summary

    The concept of alexithymia has garnered much attention in an attempt to understand the psychological mechanisms underlying the experience of feeling an emotion. In this study, we aimed to understand how the interoceptive processing in an emotional context relates to problems of alexithymia in recognizing self-emotions. Therefore, we prepared experimental conditions to induce emotional awareness based on interoceptive information. As such, we asked participants to be aware of interoception under an anxiety-generating situation anticipating pain, having them evaluate their subjective anxiety levels in this context. High alexithymia participants showed attenuated functional connectivity within their ‘interoception network’, particularly between the insula and the somatosensory areas when they focused on interoception. In contrast, they had enhanced functional connectivity between these regions when they focused on their anxiety about pain. Although access to somatic information is supposed to be more strongly activated while attending to interoception in the context of primary sensory processing, high alexithymia individuals were biased as this process was activated when they felt emotions, suggesting they recognize primitive and unprocessed bodily sensations as emotions. The paradoxical somatic information processing may reflect their brain function pathology for feeling emotions and their difficulty with context-dependent emotional control.

  • Effects of insular resection on interactions between cardiac interoception and emotion recognition

    Terasawa Y., Motomura K., Natsume A., Iijima K., Chalise L., Sugiura J., Yamamoto H., Koyama K., Wakabayashi T., Umeda S.

    Cortex (Cortex)  137   271 - 281 2021.04

    Accepted,  ISSN  00109452

     View Summary

    The insular cortex is considered an important region for feeling emotions through interoception. Most studies that report the role of the insula in integrating interoception and emotion have used neuroimaging techniques such as functional magnetic resonance imaging (fMRI); however, there are limited neuropsychological studies. The effects of insular lesions on emotion and interoception have not been suitably investigated. In this study, we examined the role of the insular cortex in cardiac interoception and recognizing emotions from facial expressions by comparing them pre- and post-operatively in patients with glial tumors or brain metastases associated with the insular lobe. Although no significant difference in interoceptive accuracy was observed between the two phases, there were significant associations between the changes in interoceptive accuracy and sensitivity to expressions of anger and happiness. An increased error rate in the heartbeat counting task in the post-operation phase was associated with a decreased accuracy in recognizing anger and happiness. Since most patients had left insula lesions, generalizability of the findings to patients with right lesions is a future subject. To the best of our knowledge, this is the first study to examine the change in interoception and emotion after insular resection in humans. The study results indicate that removal of the insula affects the recognition of emotions such as anger and happiness through interoceptive processing.

  • Altered interoceptive beliefs in alexithymia: Dissociating bias and precision using the heart rate discrimination task

    Suzuki N., Umeda S., Terasawa Y.

    Acta Psychologica 270   107672 2026.10

    ISSN  00016918

     View Summary

    Alexithymia has been widely associated with altered interoception, yet empirical findings remain inconsistent, partly because prior research has insufficiently examined the multidimensional components of interoception. This study aimed to provide a more comprehensive understanding of the relationship between alexithymia and interoception by independently examining the associations on interoceptive sensibility and interoceptive belief with alexithymia, while controlling for depression and trait anxiety. 86 undergraduate and graduate students completed questionnaires assessing alexithymia, interoceptive sensibility, depression, anxiety, and autistic traits. Interoceptive belief was measured using the Heart Rate Discrimination task, which provides psychophysical estimates of bias and precision in cardiac interoceptive judgements, alongside an exteroceptive condition. Results showed that alexithymia was selectively related to altered interoceptive belief. Difficulty describing feelings was associated with biased overestimation of cardiac activity, whereas externally oriented thinking was associated with reduced precision, indicating greater uncertainty in interoceptive belief. Path analysis further showed that reduced precision in interoceptive belief uniquely predicted externally oriented thinking, independent of depressive and anxiety symptoms. Interoceptive sensibility was evaluated using the Japanese version of the Multidimensional Assessment on Interoceptive Awareness. Results indicated that higher levels of alexithymia were associated with reduced adaptive interoceptive sensibility across multiple dimensions of bodily awareness. These findings suggest that while diminished interoceptive sensibility characterizes the subjective experience of alexithymia, altered interoceptive belief plays a more proximal role in its cognitive core, highlighting the importance of belief-based mechanisms in emotional inference.

  • The role of interoception in menstrual-related affective variability

    Terasawa Yuri

    The Journal of The Japan Society for Menopause and Women's Health (The Japan Society for Menopause and Women's Health)  33 ( 3 ) 393 - 396 2026.07

    ISSN  21858861

     View Summary

    <p>本稿は,女性の月経周期に伴う感情変動のメカニズムを,身体内部の情報を知覚する「内受容感覚」という視点から検討することを目的とした.従来,月経前の黄体期における不安や抑うつ,易怒性といった精神症状は,性ホルモンの変動に伴う中枢および末梢の神経活動の変化と関連付けて考えられることが多かった.しかし,同一の生理的変化が生じていても症状の現れ方には著しい個人差がある.この個人差の要因として,身体の状態を知覚する内受容感覚の処理プロセスに着目した.女性50名を対象に,卵胞期と黄体期の2回にわたり,自律神経活動の測定,心拍カウント課題による内受容感覚の正確さの評価,および心理尺度(MAIA,STAI,PMDD評価尺度)を用いた調査を実施した.分析の結果,安静時の心拍数には周期による差は見られなかったものの,自身の身体に注意を向ける心拍カウント課題時において,黄体期は卵胞期よりも交感神経活動が有意に高まることが示された.心理的側面では,黄体期における状態不安の増大は,身体感覚と感情の関連性に敏感な傾向(MAIA―因子5:感情への気づき」)と強い正の相関を示した.さらに,卵胞期において心拍を正確に知覚できる個人ほど,PMDD症状を強く自覚していることが明らかとなった.以上の結果から,内受容感覚を通じた身体状態の受容・解釈プロセスが,月経に伴うネガティブ感情の変動の個人差に関与している可能性が示唆された.内受容感覚という視点の導入により,個々の女性が自身の身体信号をどのように受け止め,感情や思考と統合しているかを解明する鍵となることが期待される.</p>

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Papers, etc., Registered in KOARA 【 Display / hide 】

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Reviews, Commentaries, etc. 【 Display / hide 】

  • 内受容感覚を媒介とするアロスタシスと感情

    寺澤 悠理, 是木 明宏

    BRAIN and NERVE (医学書院)  75 ( 11 ) 1251 - 1257 2023.11

    Article, review, commentary, editorial, etc. (scientific journal), Joint Work, Lead author

  • 内受容感覚とアロスタシスからみた精神疾患

    是木 明宏, 寺澤 悠理

    BRAIN and NERVE (医学書院)  75 ( 11 ) 1245 - 1250 2023.11

    Article, review, commentary, editorial, etc. (scientific journal), Joint Work

  • Effects of insular resection on interactions between cardiac interoception and emotion recognition

    Yuri Terasawa and Kazuya Motomura and Atsushi Natsume and Kentaro Iijima and Lushun Chalise and Junko Sugiura and Hiroyasu Yamamoto and Kyohei Koyama and Toshihiko Wakabayashi and Satoshi Umeda

    Cortex (Elsevier {BV})  137   271 - 281 2021.02

    Article, review, commentary, editorial, etc. (scientific journal)

  • Interoception and Mental Health: A Roadmap

    Khalsa, S.S. and Adolphs, R. and Cameron, O.G. and Critchley, H.D. and Davenport, P.W. and Feinstein, J.S. and Feusner, J.D. and Garfinkel, S.N. and Lane, R.D. and Mehling, W.E. and Meuret, A.E. and Nemeroff, C.B. and Oppenheimer, S. and Petzschner, F.H. and Pollatos, O. and Rhudy, J.L. and Schramm, L.P. and Simmons, W.K. and Stein, M.B. and Stephan, K.E. and Van den Bergh, O. and Van Diest, I. and von Leupoldt, A. and Paulus, M.P. and Ainley, V. and Al Zoubi, O. and Aupperle, R. and Avery, J. and Baxter, L. and Benke, C. and Berner, L. and Bodurka, J. and Breese, E. and Brown, T. and Burrows, K. and Cha, Y.-H. and Clausen, A. and Cosgrove, K. and Deville, D. and Duncan, L. and Duquette, P. and Ekhtiari, H. and Fine, T. and Ford, B. and Garcia Cordero, I. and Gleghorn, D. and Guereca, Y. and Harrison, N.A. and Hassanpour, M. and Hechler, T. and Heller, A. and Hellman, N. and Herbert, B. and Jarrahi, B. and Kerr, K. and Kirlic, N. and Klabunde, M. and Kraynak, T. and Kriegsman, M. and Kroll, J. and Kuplicki, R. and Lapidus, R. and Le, T. and Hagen, K.L. and Mayeli, A. and Morris, A. and Naqvi, N. and Oldroyd, K. and Pan{\'e}-Farr{\'e}, C. and Phillips, R. and Poppa, T. and Potter, W. and Puhl, M. and Safron, A. and Sala, M. and Savitz, J. and Saxon, H. and Schoenhals, W. and Stanwell-Smith, C. and Teed, A. and Terasawa, Y. and Thompson, K. and Toups, M. and Umeda, S. and Upshaw, V. and Victor, T. and Wierenga, C. and Wohlrab, C. and Yeh, H.-W. and Yoris, A. and Zeidan, F. and Zotev, V. and Zucker, N.

    Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 3 ( 6 ) 501 - 513 2018

    ISSN  24519030 24519022

  • 感情認識における島皮質の機能

    TERASAWA Yuri

    神経心理学 30 ( 1 ) 61 - 68 2014.03

    Article, review, commentary, editorial, etc. (scientific journal)

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Presentations 【 Display / hide 】

  • TEMPORAL AND AFFECTIVE ORIENTATION OF THOUGHT IN DEPRESSION AND ANXIETY: AN ERP AND HEP STUDY

    Ito, Yuichi, Shibata, Midori, Tanaka, Yuto, Terasawa, Yuri, Umeda, Satoshi

    [International presentation]  PSYCHOPHYSIOLOGY, 

    2017.12
    , 

    Poster presentation

  • FEELING CHANGES OF INTERNAL BODILY STATE DURING EMOTIONAL RECOGNITION: AN ERP AND HEP STUDY

    Tanaka, Yuto, Ito, Yuichi, Shibata, Midori, Terasawa, Yuri, Umeda, Satoshi

    [International presentation]  PSYCHOPHYSIOLOGY, 

    2017.12
    , 

    Poster presentation

Research Projects of Competitive Funds, etc. 【 Display / hide 】

  • Intervention for Menstruation-Related Difficulties in Emotion Regulation Through Interoception and Emotion Labeling

    2026.06
    -
    2029.03

    Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Research (Exploratory), Principal investigator

     View Summary

    月経随伴症とは月経のおよそ2週間前から始まる黄体期に繰り返し出現する倦怠感や痛み、
    制御が困難な抑うつや怒りといった心身の不快な症状で心身症の一つとされる。本研究では、心身症の心理的要因の一つであるアレキシサイミア傾向に注目し、その構成で重要な(1)感情の言語化と(2)内受容感覚に着目した介入研究を実施する。(1)にはジャーナリングを、(2)には申請者が開発したスマートフォンアプリを利用する。2か月間の介入前後に月経に伴う気分変動の程度、月経随伴症、心身症状、アレキシサイミア、内受容感覚などを調査し、介入が月経に伴う気分変動の大きさや感情制御の困難さの軽減に効果をもたらすかを検討する。

  • The influence of interoceptive abilities on emotion recognition

    2024.04
    -
    2028.03

    Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), No Setting

     View Summary

    本研究では不安傾向やアレキシサイミア(失感情語症)傾向に着目し、感情の認識に内受容感覚(身体内部状態の知覚)の諸側面が及ぼす影響を検討し、因果関係の解明と効果的な介入方法の確立を目指す。感情認識と内受容感覚の関連性は、広く研究者の興味をひいてきた一方、内受容感覚の測定方法の信頼性・妥当性の問題や、複数の測定方法のそれぞれが何を測定対象にしているのか、という議論がないがしろにされた状況にある。不安やアレキシサイミアなどの感情認識傾向との関係性を把握した後に、それぞれの傾向と特に強く関連した内受容感覚の側面を変化させるトレーニングを実施し、その変化が感情認識に及ぼす影響を明らかにする。

  • 眼窩前頭皮質の自律神経機能解明:脳神経外科学・認知神経機能学からの統合的理解

    2024.04
    -
    2027.03

    Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), No Setting

     View Summary

    この研究において、自律神経機能の同定と機能温存、経時的な機能回復を目的とした次世代型覚醒下手術法の確立を目標とする。また、自律神経系ネットワークの早期回復を目指し、脳腫瘍患者の術後の生命予後の改善のみならず、機能予後改善を図ることを主眼に置いた治療を行う。
    眼窩前頭皮質が自律神経と密接に関わることをヒトで検討できる脳神経外科学と、ヒトの感情や自律神経機能を多角的に捉えることができる認知神経科学が、分野融合型の共同研究を行うことは大変意義深いと考える。

  • 気圧変化に伴う自律神経の応答と気分の揺らぎに関する認知神経科学研究

    2022.06
    -
    2026.03

    Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Research (Pioneering), No Setting

     View Summary

    我が国では気分障害の患者数が非常に多く,その原因となるメカニズム解明が求められている.実際,さまざまな療法では症状の改善が見られない「ノンリスポンダー」も一定数含まれる.その背景には,自律神経の応答性に個人差がある点,および自らの心臓の動きなどの自律神経活動の変化をどれだけ正確に感じ取ることができるかを示す指標である「内受容感覚」にも個人差がある点が関与している.また生活環境内には,気圧の変化など,自律神経活動を大きく作用する要因がある.そこで本研究では,気圧変化が気分変化とどのような関係にあるかについて,「心ー脳ー身体ー環境」の4者関係の複雑なメカニズム解明を通して明らかにする予定である.
    本研究は,精神疾患における気分のゆらぎと身体化の原因について,生活環境要因と心理的要因の効果を統合的に分析することを目的としている.気分の揺らぎはさまざまな原因によって起こる上に,身体化の背景には非常に複雑な要因が関わるため,身体生理機能・中枢神経機能に加え,主観的指標・客観的指標の両者を用いた心理的機能に着目する必要がある.今年度は,気圧の変化およびそれに対する内受容感覚に着目した実験を実施した.具体的には,身体化のなかでも慢性疼痛に深く関与されると考えられる気圧変化の影響について,健常者および身体症状症の症例を対象とした研究を実施した.特に,さまざまな部位に痛みが生じている患者に対して,複数の質問紙による主観報告を確認し,意思決定や感情処理のバイアスかあるか,痛み閾値に特殊性が見出されるか,痛みの感じ方に違いはあるか,などの側面について徹底的な解析を行い,さらに気圧変化時の自律神経動態について詳しく調べた.また自律神経に変化が生じていない状態および生じている状態における内受容感覚を詳細に調べ,主観・客観の両側面から多角的な実験データが取得できた.正確な感知が困難である気圧の変化に対する予測的反応性に着目し,自律神経の反応性をパターン別に分析し,それらの違いがどのような要因によって説明できるかを統合的に解析した.今後も,この実験と解析を継続し,総合的な観点から気分のゆらぎや痛みが生起されるメカニズムについて調べる.
    身体症状症研究については,当初,倫理審査審査に時間を要していたが,今年度は順調にリクルートが進み,順調なデータの取得ができている.臨床研究はさまざまな要因によって実験が計画通りに進まないことが多いが,本研究はその点では非常に順調に実験が進められており,データ解析も計画通りに進行している.このペースで次年度の研究も進める予定である.今後は対照となる健常者の実験も同時並行で進めることで,研究の遅れが出ないように工夫する.
    上述のとおり,本研究の遂行は順調であり,今後は患者群に加え,健常群対象の実験も同時並行で進める予定である.データが安定している部分については,積極的に学会での発表などを行い,専門家の意見を広く取り入れ,データの解釈に活かしていく予定である.

  • Investigating the autonomic nervous system function associated with the insular cortex using awake brain mapping

    2021.04
    -
    2024.03

    Nagoya University, Grants-in-Aid for Scientific Research, MOTOMURA KAZUYA, Grant-in-Aid for Scientific Research (C), No Setting

     View Summary

    In this study, we analyzed how autonomic function is altered by insular gyrus removal. Furthermore, by directly stimulating the insular cortex during awake surgery, measuring ECG, heart rate and blood pressure changes, and performing a heartbeat detection task, the aim of this study was to elucidate the neural basis of autonomic functional activity in the insular cortex and establish a next-generation awake brain surgery method to identify autonomic function, preserve function and restore function over time.
    The performance of direct stimulation and heartbeat detection tasks, as well as their relationship to the surgical site, was investigated in a statistical analysis. Analysis is currently underway in 13 patients who were able to be enrolled, and it has been found that cardiac output tends to decrease as a result of the decrease in systolic blood pressure and increase in peripheral vascular resistance caused by insular stimulation.

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Courses Taught 【 Display / hide 】

  • INTENSIVE SEMINAR: PSYCHOLOGY 2

    2026

  • EXPERIMENT : SPECIAL STUDY OF PSYCHOLOGY 1

    2026

  • PSYCHOLOGY 2

    2026

  • PSYCHOLOGY 1

    2026

  • GRADUATION THESIS

    2026

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