Mitani, Ryosuke



Graduate School of Science and Technology (Yagami)


Project Assistant Professor (Non-tenured)/Project Research Associate (Non-tenured)/Project Instructor (Non-tenured)

Career 【 Display / hide

  • 2021.04

    大阪府立大学 日本学術振興会 特別研究員(DC2)

Academic Background 【 Display / hide

  • 2014.04

    大阪府立大学, 工学域, 物質化学系学類 化学工学課程

  • 2018.04

    Osaka Prefecture University, Graduate School of Engineering, Department of Chemical Engineering


Research Areas 【 Display / hide

  • Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Transport phenomena and unit operations

Research Keywords 【 Display / hide

  • Aerosol

  • Chemical Engineering

  • Powder Technology

  • 製剤学


Papers 【 Display / hide

  • Numerical study on deposition of non-spherical shaped particles in cascade impactor

    Ryosuke Mitani, Shuji Ohsaki, Hideya Nakamura, Satoru Watano

    Advanced Powder Technology (Elsevier BV)  34 ( 6 ) 104045 - 104045 2023.06

    Accepted,  ISSN  0921-8831

  • Analysis of Adhesion Mechanism of DPIs in Oral Cavity

    Ryosuke Mitani, Shuji Ohsaki, Hideya Nakamura, Satoru Watano

    Journal of the Society of Powder Technology, Japan (The Society of Powder Technology, Japan)  58 ( 3 ) 127 - 137 2021.03

    Lead author, Accepted,  ISSN  1883-7239

  • Numerical Study on Particle Adhesion in Dry Powder Inhaler Device

    Ryosuke Mitani, Shuji Ohsaki, Hideya Nakamura, Satoru Watano

    Chemical and Pharmaceutical Bulletin (Pharmaceutical Society of Japan)  68 ( 8 ) 726 - 736 2020.08

    Lead author, Accepted,  ISSN  0009-2363

     View Summary

    © 2020 The Pharmaceutical Society of Japan This study investigated the particle adhesion mechanism in a capsule of dry powder inhaler (DPI) based on a combined computational fluid dynamics and discrete element method (CFD–DEM) approach. In this study, the Johnson–Kendall–Roberts (JKR) theory was selected as the adhesion force model. The simulation results corroborated the experimental results—numerous particles remained on the outlet side of the capsule, while a few particles remained on the inlet side. In the computer simulation, the modeled particles were placed in a capsule. They were quickly dispersed to both sides of the capsule, by air fed from one side of the capsule, and delivered from the air inlet side to the outlet side of the capsule. It was confirmed that vortex flows were seen at the outlet side of the capsule, which, however, were not seen at the inlet side. Numerous collisions were observed at the outlet side, while very few collisions were observed at the inlet side. These results suggested that the vortex flows were crucial to reduce the amount of residual particles in the capsule. The original capsule was then modified to enhance the vortex flow in the area, where many particles were found remaining. The modified capsule reduced the number of residual particles compared to the original capsule. This investigation suggests that the CFD–DEM approach can be a great tool for understanding the particle adhesion mechanism and improving the delivery efficiency of DPIs.

  • Effect of Particle–Wall Interaction and Particle Shape on Particle Deposition Behavior in Human Respiratory System

    Shuji Ohsaki, Ryosuke Mitani, Saki Fujiwara, Hideya Nakamura, Satoru Watano

    Chemical and Pharmaceutical Bulletin (Pharmaceutical Society of Japan)  67 ( 12 ) 1328 - 1336 2019.12

    Accepted,  ISSN  0009-2363

Reviews, Commentaries, etc. 【 Display / hide

  • Analysis of Non-spherical Particles Behavior in Gas Phase

    三谷亮介, 綿野哲

    ホソカワ粉体工学振興財団年報(Web) 29 2022

    ISSN  2189-4663

Research Projects of Competitive Funds, etc. 【 Display / hide

  • Development of a Health Effect Evaluation System for Particulate Matter Characteristics for the Central Asian Region


    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Fund for the Promotion of Joint International Research (International Collaborative Research), No Setting

  • 異形粒子の気相中ダイナミクスと粒子の肺内挙動の解析への応用


    日本学術振興会, 科学研究費助成事業, 特別研究員奨励費, No Setting

     View Summary


Awards 【 Display / hide

  • PARTEC 2019 International Congress on Particle Technology Poster Award


  • 製剤機械技術学会第28回大会 優秀賞


  • 化学工学会第83年会 優秀学生賞

    2018.03, 化学工学会