OHBA Yohsuke

写真a

Affiliation

Faculty of Pharmacy, Department of Pharmacy 代謝生理化学講座 (Shiba-Kyoritsu)

Position

Assistant Professor/Senior Assistant Professor

Contact Address

東京都港区芝公園1-5-30

Career 【 Display / hide

  • 2015.04
    -
    2016.01

    東京大学, 薬学系研究科, 助教

  • 2016.02
    -
    2020.09

    Max Planck Institute for Biology of Ageing, ポストドクトラルフェロー

  • 2020.10
    -
    2022.04

    武田薬品工業, 研究員

  • 2022.05
    -
    Present

    慶應義塾大学, 薬学部, 専任講師

Academic Background 【 Display / hide

  • 2006.04
    -
    2010.03

    The University of Tokyo, Pharmaceutical Sciences, 薬学科

    University, Graduated

  • 2010.04
    -
    2012.03

    The University of Tokyo, 薬学系研究科

    Graduate School, Completed, Master's course

  • 2012.04
    -
    2015.03

    The University of Tokyo, 薬学系研究科

    Graduate School, Completed, Doctoral course

Academic Degrees 【 Display / hide

  • 博士(薬科学), The University of Tokyo, Coursework, 2015.03

    小胞体ストレス応答分子IRE1を介した膜脂肪酸ストレス応答機構の解明

 

Research Areas 【 Display / hide

  • Life Science / Cell biology

Research Keywords 【 Display / hide

  • ミトコンドリア

  • リン脂質

  • 脂質輸送タンパク質

 

Papers 【 Display / hide

  • Regulation of mitochondrial proteostasis by the proton gradient

    M Patron, D Tarasenko, H Nolte, L Kroczek, M Ghosh, Y Ohba, Y Lasarzewski, ZA Ahmadi, A Cabrera-Orefice, A Eyiama, T Kellermann, EI Rugarli, U Brandt, M Meinecke, T Langer

    The EMBO Journal    e110476 2022.08

    Research paper (scientific journal), Joint Work, Accepted

  • Lipid signaling drives proteolytic rewiring of mitochondria by YME1L

    MacVicar, T.*, Ohba, Y.*, Nolte, H., Mayer, F.C., Tatsuta, T., Sprenger, HG., Lindner, B., Zhao, Y., Li, J., Bruns, C., Krüger, M., Habich, M., Riemer, J., Schwarzer, R., Pasparakis, M., Henschke, S., Brüning, J.C., Zamboni, N., and Langer, T.

    Nature  ( 575 ) 361 - 365 2019

    Research paper (scientific journal), Joint Work, Lead author, Accepted

  • PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria

    Saita, S., Tatsuta, T., Lampe, A.P., König, T., Ohba, Y., and Langer, T.

    The EMBO Journal    e97909 2018

    Research paper (scientific journal), Joint Work, Accepted

  • Mitochondria-type GPAT is required for mitochondrial fusion

    Ohba, Y., Sakuragi, T., Kage-Nakadai, E., Tomioka, N.H., Kono, N., Imae, R., Inoue, A., Aoki, J., Ishihara, N., Inoue, T., Mitani, S. and Arai, H.

    The EMBO Journal  ( 32 ) 1265 - 1279 2013

    Research paper (scientific journal), Joint Work, Lead author, Accepted

  • LYCAT, a homologue of C. elegans acl-8, acl-9 and acl-10, determines the fatty acid composition of phosphatidylinositol in mice

    Imae, R., Inoue, T., Nakasaki, Y., Uchida, Y., Ohba, Y., Kono, N., Nakanishi, H., Sasaki, T., Mitani, S. and Arai, H.

    Journal of Lipid Research  ( 53 ) 335 - 357 2012

    Research paper (scientific journal), Joint Work, Accepted

Reviews, Commentaries, etc. 【 Display / hide

  • 酸素欠乏によるミトコンドリアタンパク質のリプログラミング

    大場陽介

    実験医学  ( 38 ) 995 - 998 2020

    Article, review, commentary, editorial, etc. (other), Single Work, Lead author

  • Regulation of mitochondrial plasticity by the i-AAA protease YME1L

    Ohba, Y., MacVicar, T. and and Langer, T.

    Biological Chemistry  ( 401 ) 877 - 890 2020

    Joint Work, Lead author

  • 脂質異常とオルガネラストレス

    大場陽介、河野望

    医学のあゆみ  ( 245 ) 382 - 388 2015

    Joint Work, Lead author

  • リン脂質脂肪酸鎖メタボロームと代謝疾患

    大場陽介、河野望、新井洋由

    内分泌・糖尿病・代謝内科  ( 41 ) 341 - 346 2015

    Joint Work

Research Projects of Competitive Funds, etc. 【 Display / hide

  • 膜脂質環境によるミトコンドリアプロテアーゼ活性制御機構の解明

    2023.04
    -
    2026.03

    基盤研究(C), Principal investigator

 

Courses Taught 【 Display / hide

  • STUDY OF MAJOR FIELD: (PHYSIOLOGICAL CHEMISTRY AND METABOLISM)

    2023

  • SEMINAR: (PHYSIOLOGICAL CHEMISTRY AND METABOLISM)

    2023

  • RESEARCH FOR BACHELOR'S THESIS 1

    2023

  • PHARMACEUTICAL-ENGLISH SEMINAR

    2023

  • HUMAN PHYSIOLOGY 2

    2023

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