Papers - Mashino, Tadahiko
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Fullerene derivatives as dual inhibitors of HIV-1 reverse transcriptase and protease
Yasuno T., Ohe T., Kataoka H., Hashimoto K., Ishikawa Y., Furukawa K., Tateishi Y., Kobayashi T., Takahashi K., Nakamura S., Mashino T.
Bioorganic and Medicinal Chemistry Letters (Bioorganic and Medicinal Chemistry Letters) 31 2021.01
ISSN 0960894X
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Tateishi Y., Ohe T., Ogawa M., Takahashi K., Nakamura S., Mashino T.
ACS Omega (ACS Omega) 5 ( 50 ) 32608 - 32616 2020.12
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Synthesis and evaluation of nevirapine analogs to study the metabolic activation of nevirapine
Tateishi Y., Ohe T., Yasuda D., Takahashi K., Nakamura S., Kazuki Y., Mashino T.
Drug Metabolism and Pharmacokinetics (Drug Metabolism and Pharmacokinetics) 35 ( 2 ) 238 - 243 2020.04
ISSN 13474367
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Yasuda D., Ohe T., Takahashi K., Imamura R., Kojima H., Okabe T., Ichimura Y., Komatsu M., Yamamoto M., Nagano T., Mashino T.
Free Radical Research (Free Radical Research) 2020
ISSN 10715762
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Uchihara Y., Ohe T., Mashino T., Kidokoro T., Tago K., Tamura H., Funakoshi-Tago M.
Pharmacological Reports (Pharmacological Reports) 71 ( 6 ) 1067 - 1078 2019.12
ISSN 17341140
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Synthesis and antitumor activity of novel pyridinium fullerene derivatives
Yasuno T., Ohe T., Ikeda H., Takahashi K., Nakamura S., Mashino T.
International Journal of Nanomedicine (International Journal of Nanomedicine) 14 6325 - 6337 2019
ISSN 11769114
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Synthesis of novel benzbromarone derivatives designed to avoid metabolic activation
Tomoyuki Ohe, Ryutaro Umezawa, Yumina Kitagawara, Daisuke Yasuda, Kyoko Takahashi, Shigeo Nakamura, Akiko Abe, Shuichi Sekine, Kousei Ito, Kentaro Okunushi, Hanae Morio, Tomomi Furihata, Naohiko Anzai, and Tadahiko Mashino*
Bioorg Med Chem Lett 28 3708 - 3711 2018.12
Research paper (scientific journal), Joint Work, Accepted
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A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis
Niino Tomomi, Tago Kenji, Yasuda Daisuke, Takahashi Kyoko, Mashino Tadahiko, Tamura Hiroomi, Funakoshi-Tago Megumi
Biochemical Pharmacology 155 182 - 197 2018.09
Research paper (scientific journal), Joint Work, Accepted
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Uchihara Y., Kidokoro T., Tago K., Mashino T., Tamura H., Funakoshi-Tago M.
European Journal of Pharmacology (European Journal of Pharmacology) 825 1 - 9 2018.04
ISSN 00142999
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Hit-to-lead in academia: Discovery of a protein-protein interaction inhibitor of Keap1-Nrf2
Yasuda D., Obata R., Takahashi K., Ohe T., Mashino T.
Yakugaku Zasshi (Yakugaku Zasshi) 138 ( 8 ) 1059 - 1065 2018
ISSN 00316903
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Discovery of benzo[g]indoles as a novel class of non-covalent Keap1-Nrf2 protein-protein interaction inhibitor
Yasuda, D., Yuasa, A., Obata, R., Nakajima M., Takahashi, K., Ohe, T., Ichimura, Y., Komatsu, M., Yamamoto, M., Imamura, R., Kojima, H., Okabe, T., Nagano, T., and Mashino, T.
Bioorg Med Chem Lett 27 ( 22 ) 5006 - 5009 2017.11
Research paper (scientific journal), Joint Work, Accepted
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alpha-Tocopherol attenuates the anti-tumor activity of crizotinib against cells transformed by NPM-ALK
Funakoshi-Tago, M., Uchihara, Y., Ueda, F., Tago, K., Nakazawa, Y., Ohe, T., Mashino, T., Yokota, S., Kasahara, T., and Tamura, H.
PLOS ONE 12 ( 8 ) e0183003 2017.08
Research paper (scientific journal), Joint Work, Accepted
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Synthesis of Keap1-phosphorylated p62 and Keap1-Nrf2 protein-protein interaction inhibitors and their inhibitory activity
MASHINO Tadahiko
Bioorg Med Chem Lett 26 ( 24 ) 5956 - 5959 2016.12
Research paper (scientific journal), Joint Work, Accepted
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Potential suppressive effects of two C60 fullerene derivatives on acquired immunity
MASHINO Tadahiko
Nanoscale Res Lett 11 449 2016.11
Research paper (scientific journal), Joint Work, Accepted
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Novel fullerene derivatives as dual inhibitors of Hepatitis C virus NS5B polymerase and NS3/4A protease
MASHINO Tadahiko
Bioorg Med Chem Lett, 26 4565 - 4567 2016.10
Research paper (scientific journal), Joint Work, Accepted
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p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming
MASHINO Tadahiko
Nat Commun 7 1 - 16 2016
Research paper (scientific journal), Joint Work, Accepted
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Preparation and antioxidant/pro-oxidant activities of 3-monosubstituted 5-hydroxyoxindole derivatives
MASHINO Tadahiko
J Clin Biochem Nutr 59 165 - 173 2016
Research paper (scientific journal), Joint Work, Accepted
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A proline-type fullerene derivative inhibits adipogenesis by preventing PPARgamma activation
MASHINO Tadahiko
Biochemistry and Biophysics Reports 20 258 - 263 2016
Research paper (scientific journal), Joint Work, Accepted
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Novel bioactivation pathway of benzbromarone mediated by cytochrome P450
Kitagawara Yumina, Ohe Tomoyuki, Tachibana Kumiko, Takahashi Kyoko, Nakamura Shigeo, Mashino Tadahiko
Drug Metabolism and Disposition 43 ( 9 ) 1303 - 1306 2015.09
Research paper (scientific journal), ISSN 0090-9556
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The human immunodeficiency virus-reverse transcriptase inhibition activity of novel pyridine/pyridinium-type fullerene derivatives
Yasuno Takumi, Ohe Tomoyuki, Takahashi Kyoko, Nakamura Shigeo, Mashino Tadahiko
Bioorganic and Medicinal Chemistry Letters 25 ( 16 ) 3226 - 3229 2015.07
Research paper (scientific journal), ISSN 0960-894X
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Pyrrolidinium fullerene induces apoptosis by activation of procaspase-9 via suppression of Akt in primary effusion lymphoma
Watanabe Tadashi, Nakamura Shigeo, Ono Toshiya, Ui Sadaharu, Yagi Syota, Kagawa Hiroki, Watanabe Hisami, Ohe Tomoyuki, Mashino Tadahiko, Fujimuro Masahiro
Biochemical and Biophysical Research Communications 451 ( 1 ) 93 - 100 2014.08
Research paper (scientific journal), ISSN 0006-291X
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Effect of chemical modification on the ability of pyrrolidinium fullerene to induce apoptosis of cells transformed by JAK2 V617F mutant
Funakoshi-Tago, Megumi, Tsukada, Masaki, Watanabe, Toshiro, Mameda, Yuka, Tago, Kenji, Ohe, Tomoyuki, Nakamura, Shigeo, Mashino, Tadahiko, Kasahara, Tadashi
INTERNATIONAL IMMUNOPHARMACOLOGY 20 ( 1 ) 258 - 263 2014.05
Research paper (scientific journal), ISSN 1567-5769
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Antioxidant activities of 5-hydroxyoxindole and its 3-hydroxy-3-phenacyl derivatives: The suppression of lipid peroxidation and intracellular oxidative stress.
Yasuda D, Takahashi K, Ohe T, Nakamura S, Mashino T.
Bioorg Med Chem 21 7709-7714 2013.12
Research paper (scientific journal), Joint Work, Accepted
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Anti-influenza activity of c60 fullerene derivatives.
Shoji M, Takahashi E, Hatakeyama D, Iwai Y, Morita Y, Shirayama R, Echigo N, Kido H, Nakamura S, Mashino T, Okutani T, Kuzuhara T.
PLoS One 8 1-10 2013.06
Research paper (scientific journal), Joint Work, Accepted
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Synthesis, radical scavenging activity and structure-activity relationship of uric acid analogs
Yasuda Daisuke, Takahashi Kyoko, Kakinoki Tomohiro, Tanaka Yoko, Ohe Tomoyuki, Nakamura Shigeo, Mashino Tadahiko
MedChemComm 4 ( 3 ) 527 - 529 2013.03
Research paper (scientific journal), ISSN 2040-2503
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Fullerene derivative prevents cellular transformation induced by JAK2 V617F mutant through inhibiting c-Jun N-terminal kinase pathway
Funakoshi-Tago Megumi, Nagata Tatsuaki, Tago Kenji, Tsukada Masaki, Tanaka Kazuyuki, Nakamura Shigeo, Mashino Tadahiko, Kasahara Tadashi
Cellular Signalling 24 ( 11 ) 2024 - 2034 2012.11
Research paper (scientific journal), ISSN 0898-6568
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Water-soluble fullerene derivatives for drug discovery
Shigeo Nakamura; Tadahiko Mashino
Journal of Nippon Medical School 79 ( 4 ) 248 - 254 2012.08
Research paper (scientific journal)
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Impairment of heme biosynthesis induces short circadian period in body temperature rhythms in mice
Reiko Iwadate; Yoko Satoh; Yukino Watanabe; Hiroshi Kawai; Naomi Kudo; Yoichi Kawashima; Tadahiko Mashino; Atsushi Mitsumoto
American Journal of Physiology - Regulatory Integrative and Comparative Physiology 303 ( 1 ) R8 - R18 2012.07
Research paper (scientific journal)
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Isolation and structural identification of a direct-acting mutagen derived from N-nitroso-N-methylpentylamine and Fenton's reagent with copper ion
Miura Motofumi, Inami Keiko, Yoshida Masafumi, Yamaguchi Kentaro, Mashino Tadahiko, Mochizuki Masataka
Bioorganic and Medicinal Chemistry 19 ( 18 ) 5693 - 5697 2011.09
Research paper (scientific journal), ISSN 0968-0896
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Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin.
Funakoshi-Tago M*, Nakamura K, Tago K, Mashino T, Kasahara T.
Int Immunopharmacol 11(9) 1150-1159 2011.09
Research paper (scientific journal), Joint Work, Accepted
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Ipso Substitution of bisphenol A catalyzed by microsomal cytochrome P450 and Enhancement of estrogenic activity.
Nakamura S, Tezuka Y, Ushiyama A, Kawashima C, Kitagawara Yumina Takahashi K, Ohto S, Mashino T.
Toxicology Letters 203 92-95 2011.05
Research paper (scientific journal), Joint Work, Accepted
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The fixed structure of Licochalcone A by α, β-unsaturated ketone is necessary for anti-inflammatory activity through the inhibition of NF-κB activation
Funakoshi-Tago Megumi, Nakamura Kei, Tsuruya Rina, Hatanaka Masashi, Mashino Tadahiko, Sonoda Yoshiko, Kasahara Tadashi
International Immunopharmacology 10 ( 5 ) 562 - 571 2010.05
Research paper (scientific journal), ISSN 1567-5769
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Biological safety of water-soluble fullerenes evaluated using tests for genotoxicity, phototoxicity, and pro-oxidant activity
Aoshima Hisae, Yamana Shuichi, Nakamura Shigeo, Mashino Tadahiko
Journal of Toxicological Sciences 35 ( 3 ) 401 - 409 2010
Research paper (scientific journal), ISSN 0388-1350
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Pyrrolidinium-type fullerene derivative-induced apoptosis by the generation of reactive oxygen species in HL-60 cells.
Nishizawa C, Hashimoto N, Yokoo S, Funakoshi-Tago M, Kasahara T, Takahashi K, Nakamura S, Mashino T*.
Free Radical Res 43(12) 1240-1247 2009.12
Research paper (scientific journal), Joint Work, Accepted
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Licochalcone A potently inhibits tumor necrosis factor alpha-induced nuclear factor-kappaB activation through the direct inhibition of IkappaB kinase complex activation.
Funakoshi-Tago M*, Tanabe S, Tago K, Itoh H, Mashino T, Sonoda Y, Kasahara T.
Molecular Pharmacology 76(4) 745-753 2009.10
Research paper (scientific journal), Joint Work, Accepted
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Licochalcone A significantly suppresses LPS signaling pathway through the inhibition of NF-κB p65 phosphorylation at serine 276
Furusawa Jun ichi, Funakoshi-Tago Megumi, Tago Kenji, Mashino Tadahiko, Inoue Hideo, Sonoda Yoshiko, Kasahara Tadashi
Cellular Signalling 21 ( 5 ) 778 - 785 2009.05
Research paper (scientific journal), ISSN 0898-6568
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Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-κB p65 in LPS signaling pathway
Furusawa Jun ichi, Funakoshi-Tago Megumi, Mashino Tadahiko, Tago Kenji, Inoue Hideo, Sonoda Yoshiko, Kasahara Tadashi
International Immunopharmacology 9 ( 4 ) 499 - 507 2009.04
Research paper (scientific journal), ISSN 1567-5769
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Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway.
Furusawa J, Funakoshi-Tago M*, Mashino T, Tago K, Inoue H, Sonoda Y, Kasahara T.
International Immunopharmacology 9(4) 499-507 2009.04
Research paper (scientific journal), Joint Work, Accepted
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Fullerene nanowhiskers and related fullerene nanomaterials.
Miyazawa K*, Kato R, Saito K, Kizuka T, Mashino T, Nakamura S.
J Phys Conf Series 159 012007 2009.04
Research paper (scientific journal), Joint Work, Accepted
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Biological activities of water-soluble fullerene derivatives
S. Nakamura; T. Mashino
Journal of Physics: Conference Series 159 2009.01
Research paper (scientific journal)
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Fullerene nanowhiskers and related fullerene nanomaterials
Miyazawa K., Kato R., Saito K., Kizuka T., Mashino T., Nakamura S.
Journal of Physics: Conference Series 159 2009
Research paper (scientific journal), ISSN 1742-6588
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In vitro free radical scavenging activity of platinum nanoparticles
Watanabe Aki, Kajita Masashi, Kim Juewon, Kanayama Atsuhiro, Takahashi Kyoko, Mashino Tadahiko, Miyamoto Yusei
Nanotechnology 20 ( 45 ) 2009
Research paper (scientific journal), ISSN 0957-4484
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Biological activities of water-soluble fullerene derivatives
Nakamura S., Mashino T.
Journal of Physics: Conference Series 159 2009
Research paper (scientific journal), ISSN 1742-6588
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Pyrrolidinium-type fullerene derivative-induced apoptosis by the generation of reactive oxygen species in HL-60 cells
Nishizawa Chiho, Hashimoto Noriyuki, Yokoo Sachiko, Funakoshi-Tago Megumi, Kasahara Tadashi, Takahashi Kyoko, Nakamura Shigeo, Mashino Tadahiko
Free Radical Research 43 ( 12 ) 1240 - 1247 2009
Research paper (scientific journal), ISSN 1071-5762
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Licochalcone A is a potent inhibitor of TEL-Jak2-mediated transformation through the specific inhibition of Stat3 activation.
Funakoshi-Tago M*, Tago K, Nishizawa C, Takahashi K, Mashino T, Iwata S, Inoue H, Sonoda Y, Kasahara T.
Biochem Pharmacol 76(12) 1681-1693 2008.12
Research paper (scientific journal), Joint Work, Accepted
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2,2′-Pyridoin derivatives protect HL-60 cells against oxidative stress
Hatanaka Masashi, Nishizawa Chiho, Kakinoki Tomohiro, Takahashi Kyoko, Nakamura Shigeo, Mashino Tadahiko
Bioorganic and Medicinal Chemistry Letters 18 ( 19 ) 5290 - 5293 2008.10
Research paper (scientific journal), ISSN 0960-894X
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C60 nanowhisker field-effect-transistor application for nano-electronics
Ogawa Ken Ichi, Aoki Nobuyuki, Miyazawa Kun'ichi, Nakamura Shigeo, Mashino Tadahiko, Bird Jonathan P., Ochiai Yuichi
Japanese Journal of Applied Physics 47 ( 1 PART 2 ) 501 - 504 2008.01
Research paper (scientific journal), ISSN 0021-4922
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Novel metabolic pathways of p-n-nonylphenol catalyzed by cytochrome P450 and estrogen receptor binding activity of new metabolites
Tezuka Yoshito, Takahashi Kyoko, Suzuki Tomoharu, Kitamura Shigeyuki, Ohta Shigeru, Nakamura Shigeo, Mashino Tadahiko
Journal of Health Science 53 ( 5 ) 552 - 561 2007.10
Research paper (scientific journal), ISSN 1344-9702
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Solubilization of dipropofol, an antibacterial agent, using saccharide and ascorbic acid
Masahiro Ogata; K. Oka; Masako Seki; Midori Hoshi; Hirokatsu Takatsu; Tadahiko Mashino; Shiro Urano; Toyoshige Endo
Biological and Pharmaceutical Bulletin 30 ( 8 ) 1565 - 1568 2007.08
Research paper (scientific journal)
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Iron-chelating agents never suppress Fenton reaction but participate in quenching spin-trapped radicals.
Li L, Abe Y, Kanagawa K, Shoji T, Mashino T, Mochizuki M, Tanaka M, Miyata N.
Analytica Chimica Acta 599 315-319 2007.08
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Novel Metabolic Pathways of p-n-Nonylphenol Catalyzed by Cytochrome P450 and Estrogen Receptor Binding Activity of New Metabolites.
Tezuka Y, Takahashi K, Suzuki T, Kitamura S, Ohta S, Nakamura S, Mashino T*.
J Health Sci 53(5) 552-561 2007.07
Research paper (conference, symposium, etc.), Joint Work, Accepted
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DMPO-OH Radical Formation form 5,5-Dimethyl-1-pyrroline N-Oxide (DMPO) in Hot Water.
Shoji T, Li L, Abe Y*, Ogata M, Ishimoto Y, Gonda R, Mashino T, Mochizuki M, Uemoto M, Miyata N.
Analytical Sciences 23 219-221 2007.02
Research paper (conference, symposium, etc.), Joint Work, Accepted
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TEM and Raman spectroscopy analyses of fullerene nanowhiskers and nanotubes
Miyazawa K., Ringor C., Nakamura K., Tachibana M., Mashino T., Nakamura S.
124 - 127 2007
Research paper (international conference proceedings), Joint Work
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Structural characterization of room-temperature synthesized fullerene nanowhiskers.
Miyazawa K*, Minato J, Mashino T, Nakamura S, Fujino M, Suga T.
NUKLEONIKA 51 S41−48 2006.06
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Synthesis of novel amino acid-type fullerenes and their inhibition activity of HIV reverse transcriptase and HCV RNA polymerase.
Nakamura S, Ikegami N, Harada M, Shimotohno K, Takahashi K, Mashino T*.
J Kyoritsu Univ Pharm 1 77-84 2006.03
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Metabolic conversion of 24-methyl-D25-cholesterol to 24-methylcholesterol in higher plants.
Takahashi K*, Nasu K, Mashino T, Morisaki M, Hara N, Fujimoto Y.
Bioorg Med Chem 14 732-738 2006.01
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Structural characterization of room-temperature synthesized fullerene nanowhiskers
Miyazawa Kun'ichi, Minato Jun Ichi, Mashino Tadahiko, Nakamura Shigeo, Fujino Masahisa, Suga Tadatomo
Nukleonika 51 ( SUPPL. 1 ) 2006
Research paper (scientific journal), ISSN 0029-5922
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Preparation and antioxidant activity of α-pyridoin and its derivatives
Hatanaka Masashi, Takahashi Kyoko, Nakamura Shigeo, Mashino Tadahiko
Bioorganic and Medicinal Chemistry 13 ( 24 ) 6763 - 6770 2005.12
Research paper (scientific journal), ISSN 0968-0896
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Biodegradable polymers in chondrogenesis of human articular chondrocytes
Banu Nasreen, Banu Yasmin, Sakai Masamune, Mashino Tadahiko, Tsuchiya Toshie
Journal of Artificial Organs 8 ( 3 ) 184 - 191 2005.09
Research paper (scientific journal), ISSN 1434-7229
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Human immunodeficiency virus-reverse transcriptase inhibition and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of fullerene derivatives.
Mashino T*, Shimotohno K, Ikegami N, Nishikawa D, Okuda K, Takahashi K, Nakamura S, Mochizuki M.
Bioorg Med Chem Lett 15 1107-1109 2005.01
Research paper (conference, symposium, etc.), Joint Work, Accepted
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An HPLC assay of hydroxyl radicals by the hydroxylation reaction of terephthalic acid.
Li L, Abe Y*, Nagasawa Y, Kudo R, Usui N, Imai K, Mashino T, Mochizuki M, Miyata N.
Biomedical Chromatography 18 470-474 2004.09
Research paper (conference, symposium, etc.), Single Work, Accepted
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Distinguishing the 5,5-dimethyl-1-pyrroline N-oxide (DMPO)-OH radical quenching effect from the hydroxyl radical scavenging effect in the ESR spin-trapping method.
Li L, Abe Y*, Kanagawa K, Usui N, Imai K, Mashino T, Mochizuki M, Miyata N.
Analytica Chimica Acta 512 121-124 2004.05
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Antibacterial and antiproliferative activity of cationic fullerene derivatives.
Mashino T, Nishikawa D, Takahashi K, Usui N, Yamori T, Seki M, Endo T, Mochizuki M.
Bioorg Med Chem Lett 13 4395-4397 2003.12
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Structural characterization of the C60[C(COOC2H5)2] wiskers prepared by the liquid-liquid interfacial precipitation method.
Miyazawa K, Mashino T, and Suga T.
J Mater Res 18(11) 2730-2735 2003.11
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Structural characterization of the C60[C(COOC2H 5)2] whiskers prepared by the liquid-liquid interfacial precipitation method
Miyazawa Kun'ichi, Mashino Tadahiko, Suga Tadatomo
Journal of Materials Research 18 ( 11 ) 2730 - 2735 2003.11
Research paper (scientific journal), ISSN 0884-2914
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Signal enhancement in ESR spin-trapping for hydroxyl radicals.
Li L, Abe Y*, Mashino T, Mochizuki M, Miyata N.
Analytical Sciences 19 1083-1084 2003.07
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Respiratory chain inhibition by fullerene derivatives: Hydrogen peroxide production caused by fullerene derivatives and respiratory chain system.
Mashino T, Usui N, Okuda K, Hirota T, Mochizuki M.
Bioorg Med Chem 11 1433-1438 2003.04
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Synthesis of water-soluble C60-porphyrin hybrid compounds.
Okuda K, Abeta C, Hirota T, Mochizuki M, Mashino T*.
Chemical Pharmaceutical Bullitein 50 985-987 2002.07
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Effect of hexasulfobutylated C60 on the isolated aortic ring of Guinea pig.
Huang SS, Mashino T, Mochizuki M, Chiang LY, Chih LH, Hsieh HM, Teng CM, Okuda K, Hirota T, Tsai MC*.
Pharmacology 64 91-97 2002.02
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Effect of hexasulfobutylated C60 on the isolated aortic ring of guinea pig
Huang Shiang Suo, Mashino Tadahiko, Mochizuki Masataka, Chiang Long Y., Chih Lan Hui, Hsieh Hung Ming, Teng Chen Ming, Okuda Kensuke, Hirota Takasi, Tsai Ming Cheng
Pharmacology 64 ( 2 ) 91 - 97 2002
Research paper (scientific journal), ISSN 0031-7012
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Effects of hexasulfobutylated C60 on the gastric circular muscle of Gunia pig.
Huang SS, Chih LH, Lin CH, Chiang LY, Mashino T, Mochizuki M, Okuda K, Hirota T, Tsai MC*.
Fullerene Sci Tech 9(3) 375-395 2001.09
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Inhibitory effects of fullerene C60 derivatives on endothelium-derived relaxation in rabbit thoracic aorta.
Satoh M*, Mashino T, Nagano T, Hirobe M, Takayanagi I, and Koike K.
Fullerene Sci Tech 9 141-151 2001.04
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Inhibitory effect of fullerene derivatives on glutathione reductase.
Mashino T*, Okuda K, Hirota T, Hirobe M, Nagano T, Mochizuki M.
Fullerene Sci Tech 9 191-196 2001.04
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Inhibitory effect of fullerene derivatives on glutathione reductase
Mashino T., Okuda K., Hirota T., Hirobe M., Nagano T., Mochizuki M.
Fullerene Science and Technology 9 ( 2 ) 191 - 196 2001
Research paper (scientific journal), Joint Work, ISSN 1064-122X
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Inhibitory effects of fullerene C60 derivatives on endothelium-derived relaxation in rabbit thoracic aorta
Satoh M., Mashino T., Nagano T., Hirobe M., Takayanagi I., Koike K.
Fullerene Science and Technology 9 ( 2 ) 141 - 151 2001
Research paper (scientific journal), Joint Work, ISSN 1064-122X
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Antioxidant Activity and Xanthine Oxidase Inhibition Activity of Reductic Acid; Ascorbic Acid Analog.
Mashino T, Takigawa Y, Saito N, Wong L Q, Mochizuki M.
Bioorg Med Chem Lett 10 2783-2785 2000.12
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Synthesis of various water-soluble C60 derivatives and their superoxide-quenching activity.
Okuda K, Hirota T, Hirobe M, Nagano T, Mochizuki M, Mashino T.
Fullerene Sci Tech 8 89-104 2000.09
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Novel metabolic pathway of estrone and 17b-estradiol catalyzed by cytochrome P450.
Ohe T, Hirobe M, Mashino T.
Drug Metab Dispos 28 110-112 2000.01
Research paper (scientific journal), Joint Work, Accepted
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Novel metabolic pathway of estrone and 17β-estradiol catalyzed by cytochrome P-450
Mashino Tadahiko, Ohe Tomoyuki, Hirobe Masaaki
Drug Metabolism and Disposition 28 ( 2 ) 110 - 112 2000
Research paper (scientific journal), Joint Work, ISSN 0090-9556
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Inhibition of E. coli growth by fullerene derivatives and inhibition mechanism.
Mashino T, Okuda K, Hirota T, Hirobe M, Nagano T, and Mochizuki M.
Bioorg Med Chem Lett 9 2959-2962 1999.07
Research paper (conference, symposium, etc.), Joint Work, Accepted
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Inhibitory effect of a fullerene derivative, monomalonic acid C60, on nitric oxide-dependent relaxation of aortic smooth muscle
Satoh Mitsutoshi, Matsuo Kazuhiro, Kiriya Hitoshi, Mashino Tadahiko, Hirobe Masaaki, Takayanagi Issei
General Pharmacology 29 ( 3 ) 345 - 351 1997.09
Research paper (scientific journal), Joint Work, ISSN 0306-3623
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Inhibitory effects of a fullerene derivative, dimalonic acid C60, on nitric oxide-induced relaxation of rabbit aorta.
Satoh M., Matsuo K., Kiriya H., Mashino T., Nagano T., Hirobe M., Takayanagi I.
European Journal of Pharmacology 327 ( 2-3 ) 175 - 181 1997.05
Research paper (scientific journal), Joint Work, ISSN 0014-2999
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Substituent elimination from p-substituted phenols by cytochrome P450 ipso-substitution by the oxygen atom of the active species
Ohe Tomoyuki, Mashino Tadahiko, Hirobe Masaaki
Drug Metabolism and Disposition 25 ( 1 ) 116 - 122 1997.01
Research paper (scientific journal), Joint Work, ISSN 0090-9556
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Singlet oxygen production from fullerene derivatives
Hamano Takeshi, Okuda Kensuke, Mashino Tadahiko, Hirobe Masaaki, Arakane Kumi, Ryu Akemi, Mashiko Shinrou, Nagano Tetsuo
Chemical Communications ( 1 ) 21 - 22 1997
Research paper (scientific journal), Joint Work, ISSN 1359-7345
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Superoxide radical quenching and cytochrome C peroxidase-like activity of C60-dimalonic acid, C62(COOH)4
Okuda Kensuke, Mashino Tadahiko, Hirobe Masaaki
Bioorganic and Medicinal Chemistry Letters 6 ( 5 ) 539 - 542 1996.03
Research paper (scientific journal), Joint Work, ISSN 0960-894X
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Novel oxidative pathway of para-substituted phenols in cytochrome P450 chemical model
Ohe Tomoyuki, Mashino Tadahiko, Hirobe Masaaki
Tetrahedron Letters 36 ( 42 ) 7681 - 7684 1995.10
Research paper (scientific journal), Joint Work, ISSN 0040-4039
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Hydroxylation of benzene by horseradish peroxidase and immobilized horseradish peroxidase in an organic solvent
Akasaka Reiko, Mashino Tadahiko, Hirobe Masaaki
Bioorganic and Medicinal Chemistry Letters 5 ( 16 ) 1861 - 1864 1995.08
Research paper (scientific journal), Joint Work, ISSN 0960-894X
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Oxidation of [60]fullerene by cytochrome P450 chemical models
Hamano Takeshi, Mashino Tadahiko, Hirobe Masaaki
Journal of the Chemical Society, Chemical Communications ( 15 ) 1537 - 1538 1995
Research paper (scientific journal), Joint Work, ISSN 0022-4936
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Novel Metabolic Pathway of Arylethers by Cytochrome P450
Ohe T., Mashino T., Hirobe M.
Archives of Biochemistry and Biophysics 310 ( 2 ) 402 - 409 1994.05
Research paper (scientific journal), Joint Work, ISSN 0003-9861
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Hydroxylation of benzene by immobilized cytochrome c in an organic solvent
Akasaka Reiko, Mashino Tadahiko, Hirobe Masaaki
Journal of the Chemical Society, Perkin Transactions 1 ( 13 ) 1817 - 1821 1994
Research paper (scientific journal), Joint Work, ISSN 1472-7781
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Application of Chemical Cytochrome P450 Model Systems to Studies on Drug Metabolism .VI
Doi T., Mori T., Mashino T., Hirobe M.
Biochemical and Biophysical Research Communications 191 ( 2 ) 737 - 743 1993.03
Research paper (scientific journal), Joint Work, ISSN 0006-291X
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Cytochrome P450-like Substrate Oxidation Catalyzed by Cytochrome c and Immobilized Cytochrome c
Akasaka R., Mashino T., Hirobe M.
Archives of Biochemistry and Biophysics 301 ( 2 ) 355 - 360 1993.03
Research paper (scientific journal), Joint Work, ISSN 0003-9861
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Oxygen activation by iron(III)-porphyrin/NaBH4/Me4N·OH system as cytochrome P-450 model. Oxygenation of olefin, N-dealkylation of tertiary amine, oxidation of sulfide, and oxidative cleavage of ether bond
Mori T., Santa T., Higuchi T., Mashino T., Hirobe M.
Chemical and Pharmaceutical Bulletin 41 ( 2 ) 292 - 295 1993
Research paper (scientific journal), Joint Work, ISSN 0009-2363
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18O incorporation from H2 18O2 in the oxidation of N-methylcarbazole and sulfides catalyzed by microperoxidase-11
Nakamura Shigeo, Mashino Tadahiko, Hirobe Masaaki
Tetrahedron Letters 33 ( 37 ) 5409 - 5412 1992.09
Research paper (scientific journal), Joint Work, ISSN 0040-4039
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Substrate oxidation catalyzed by heme-undecapeptide, microperoxidase-11 in the presence of iodosylbenzene and cumene hydroperoxide
Nakamura S., Mashino T., Hirobe M.
Journal of Pharmacobio-Dynamics 14 ( 11 ) 1991
Research paper (scientific journal), Joint Work, ISSN 0386-846X
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Metabolism and penetration through blood-brain barrier of parkinsonism-related compounds. 1,2,3,4-Tetrahydroisoquinoline and 1-methyl-1,2,3,4-tetrahydroisoquinoline
Kikuchi K., Nagatsu Y., Makino Y., Mashino T., Ohta S., Hirobe M.
Drug Metabolism and Disposition 19 ( 1 ) 257 - 262 1991
Research paper (scientific journal), Joint Work, ISSN 0090-9556
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Sulfide oxidation, amine N-demethylation, and olefin oxidation by heme-undecapeptide, microperoxidase-11, in the presence of hydrogen peroxide
Mashino Tadahiko, Nakamura Shigeo, Hirobe Masaaki
Tetrahedron Letters 31 ( 22 ) 3163 - 3166 1990
Research paper (scientific journal), Joint Work, ISSN 0040-4039
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Metabolism and blood-brain barrier permeability of tiqs
Ohta S., Tachikawa O., Makino Y., Kikuchi K., Mashino T., Hirobe M.
Journal of Pharmacobio-Dynamics 12 ( 3 ) 1989
Research paper (scientific journal), Joint Work, ISSN 0386-846X
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The reactivity of superoxide
Yamamoto Hiroshi, Mashino Tadahiko, Nagano Tetsuo, Hirobe Masaaki
Tetrahedron Letters 30 ( 31 ) 4133 - 4136 1989
Research paper (scientific journal), Joint Work, ISSN 0040-4039
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Reactions of hypochlorite with catalase
Mashino Tadahiko, Fridovich Irwin
Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular 956 ( 1 ) 63 - 69 1988.08
Research paper (scientific journal), Joint Work, ISSN 0167-4838
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NADPH mediates the inactivation of bovine liver catalase by monochloroamine
Maskino Tadahiko, Fridovich Irwin
Archives of Biochemistry and Biophysics 265 ( 2 ) 279 - 285 1988
Research paper (scientific journal), Joint Work, ISSN 0003-9861
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Effects of urea and trimethylamine-N-oxide on enzyme activity and stability
Mashino Tadahiko, Fridovich Irwin
Archives of Biochemistry and Biophysics 258 ( 2 ) 356 - 360 1987.11
Research paper (scientific journal), Joint Work, ISSN 0003-9861
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Superoxide radical initiates the autoxidation of dihydroxyacetone
Mashino Tadahiko, Fridovich Irwin
Archives of Biochemistry and Biophysics 254 ( 2 ) 547 - 551 1987.05
Research paper (scientific journal), Joint Work, ISSN 0003-9861
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Base liberation from nucleotides by superoxide and intramolecular enhancement effect of phosphate group
Yamane Hiroshi, Yada Nobuhisa, Katori Etsu, Mashino Tadahiko, Nagano Tetsuo, Hirobe Masaaki
Biochemical and Biophysical Research Communications 142 ( 3 ) 1104 - 1110 1987.02
Research paper (scientific journal), Joint Work, ISSN 0006-291X
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Mechanism of the cyanide-catalyzed oxidation of α-ketoaldehydes and α-ketoalcohols
Mashino Tadahiko, Fridovich Irwin
Archives of Biochemistry and Biophysics 252 ( 1 ) 163 - 170 1987
Research paper (scientific journal), Joint Work, ISSN 0003-9861
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α,β-Dihydroxyisovalerate dehydratase. A superoxide-sensitive enzyme
Kuo C. F., Mashino T., Fridovich I.
Journal of Biological Chemistry 262 ( 10 ) 4724 - 4727 1987
Research paper (scientific journal), Joint Work, ISSN 0021-9258
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Epoxidations of olefins by peroxy intermediate generated in situ from CCl4 and superoxide
Yamamoto Hiroshi, Mashino Tadahiko, Nagano Tetsuo, Hirobe Masaaki
Journal of the American Chemical Society 108 ( 3 ) 539 - 541 1986
Research paper (scientific journal), Joint Work, ISSN 0002-7863
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Reduction of imines by cluster [Fe4S4(SR)4]3-
Mashino Tadahiko, Nagano Tetsuo, Hirobe Masaaki
Tetrahedron Letters 24 ( 46 ) 5113 - 5116 1983
Research paper (scientific journal), Joint Work, ISSN 0040-4039