論文 - 長谷 耕二
-
Visualization of the entire differentiation process of murine M cells: suppression of their maturation in cecal patches.
Kimura S, Yamakami-Kimura M, Obata Y, Hase K, Kitamura H, Ohno H, Iwanaga T.
Mucosal Immunol 8 650 - 660 2014年10月
研究論文(学術雑誌), 共著, 査読有り
-
Pitfalls in global normalization of ChIP-seq data in CD4(+) T cells treated with butyrate: A possible solution strategy.
Furusawa Y, Endo TA, Obata Y, Ohara O, Ohno H and Hase K.
Genome Data 2 176 - 180 2014年07月
研究論文(学術雑誌), 共著, 査読有り
-
Epigenetic regulator Uhrf1 is critical for functional expansion of colonic regulatory T cells.
#Obata Y, #Furusawa Y, Endo TA, Sharif J, Takahashi D, Atarashi K, Onawa S, Fujimura Y, Takahashi M, Ikawa T, Otsubo T, Kawamura YI, Dohi T, Tajima S, Ohara O, Honda K, Hori S, Ohno H, Koseki H and *Hase K.
Nat Immunol 15 571-579 2014年05月
研究論文(学術雑誌), 共著, 査読有り
-
Gut microbiota-generated metabolites in animal health and disease.
*Lee WJ and *Hase K.
Nat. Chem. Biol. 10 416-424 2014年05月
研究論文(学術雑誌), 共著, 査読有り
-
Treg induction by a rationally selected Clostridia cocktail from the human microbiota.
Atarashi K, Tanoue T, Oshima K, Suda W, Nagano Y, Nishikawa H, Fukuda S, Saito T, Narushima S, Hase K, Kim S, Fritz JV, Wilmes P, Ueha S, Matsushima K, Ohno H, Olle B, Sakaguchi S, Taniguchi T, Morita H, *Hattori M, *Honda K.
Nature 500 232-236 2014年03月
研究論文(学術雑誌), 共著, 査読有り
-
Selection of an aptamer against mouse GP2 by SELEX.
Hanazato M, Nakato G, Nishikawa F, Hase K, Nishikawa S and Ohno H.
Cell Struct. Funct. 39 23 - 29 2014年01月
研究論文(学術雑誌), 共著, 査読有り
-
Ubiquitin-specific protease 2-69 in macrophages potentially modulates metainflammation.
Kitamura H, Kimura S, Shimamoto Y, Okabe J, Ito M, Miyamoto T, Naoe Y,Kikuguchi C, Meek B, Toda C, Okamoto S, Kanehira K, Hase K, Watarai H, IshizukaM, El-Osta A, Ohara O, Miyoshi I.
FASEB J. 27 4940 - 4953 2013年12月
研究論文(学術雑誌), 共著, 査読有り
-
AP-1B-mediated protein sorting regulates polarity and proliferation of intestinal epithelial cells in mice.
Hase K, Nakatsu F, Ohmae M, Sugihara K, Shioda N, Takahashi D, Obata Y, Furusawa Y, Fujimura Y, Yamashita T, Fukuda S, Okamoto H, Asano M, Yonemura S and *Ohno H.
Gastroenterology 145 625-635 2013年08月
研究論文(学術雑誌), 共著, 査読有り
-
Distinct Roles for CXCR6+ and CXCR6- CD4+ T Cells in the Pathogenesis of Chronic Colitis.
18 Mandai Y, Takahashi D, *Hase K, Obata Y, Furusawa Y, Ebisawa M, Nakagawa T, Sato T, Katsuno T, Saito Y, Shimaoka T, Yokosuka O, Yokote K, Ohno H.
PLoS One 19 e65488 2013年06月
研究論文(学術雑誌), 共著, 査読有り
-
Commensal microbe-derived butyrate induces colonic regulatory T cells.
Furusawa Y, Obata Y, *Fukuda S, Endo TA, Nakato G, Takahashi D, Nakanishi Y, Uetake C, Kato K, Kato T, Takahashi M, Fukuda NR, Murakami M, Miyauchi E, Hino S, Atarashi K, Onawa S, Fujimura Y, Lockett T, Clarke JM, Topping DL, Tomita M, Hori S, Ohara O, Morita T, Koseki H, Kikuchi J, Honda K, *Hase K and *Ohno H.
Nature 500 232-236 2013年06月
研究論文(学術雑誌), 共著, 査読有り
-
Microbiota-derived lactate accelerates colon epithelial cell turnover in starvation-refed mice.
Okada T, Fukuda S, Hase K, Nishiumi S, Izumi Y, Yoshida M, Hagiwara T, Kawashima R, Yamazaki M, Oshio T, Otsubo T, Inagaki-Ohara K, Kakimoto K, Higuchi K, Kawamura Y,I,, Ohno H and *Dohi H.
Nat Commun 4 1654 2013年03月
研究論文(学術雑誌), 共著, 査読有り
-
The Ets Transcription factor Spi-B is essential for the differentiation of intestinal microfold (M) Cells.
Kanaya T, Hase K, Takahashi D, Fukuda S, Hoshino K, Sasaki I, Hemmi H, Knoop KA, Kumar N, Sato M, Katsuno T, Yokosuka O, Toyooka K, Nakai K, Sakamoto A, Kitahara Y, Jinnohara T, McSorley SJ, *Kaisho T, *Williams IR and *Ohno H.
Nat Immunol 13 729-736 2012年12月
研究論文(学術雑誌), 共著, 査読有り
-
Critical role of the IgM Fc receptor in IgM homeostasis, B-cell survival, and humoral immune responses.
Ouchida R, Mori H, Hase K, Takatsu H, Kurosaki T, Tokuhisa T, *Ohno H and *Wang J-Y.
Proc Natl Acad Sci USA 109 E2699-E2706 2012年11月
研究論文(学術雑誌), 共著, 査読有り
-
Cutting Edge: Brucella abortus exploits a cellular prion protein on intestinal M cells as an invasive receptor.
20 Nakato G, Hase K, Suzuki M, Kimura M, Ato M, Hanazato M, Tobiume M, Horiuchi M, Atarashi R, Nishida N, Watarai M, Imaoka K and Ohno H.
J. Immunol. 189 1540 - 1544 2012年08月
研究論文(学術雑誌), 査読有り
-
AP1B plays an important role in intestinal tumorigenesis with the truncating mutation of an APC gene.
25 Mimura M, Masuda A, Nishiumi S, Kawakami K, Fujishima Y, Yoshie T, Mizuno S, Miki I, Ohno H, Hase K, Minamoto T, Azuma T and Yoshida M.
Int. J. Cancer 130 1011 - 1020 2012年04月
研究論文(学術雑誌), 共著
-
Epithelial cell-intrinsic Notch signaling plays an essential role in the maintenance of gut immune homeostasis.
Obata Y, Takahashi D, Ebisawa M, Kakiguchi M, Yonemura S, Jinnohara T, Kanaya T, Fujimura Y, Ohmae M, Hase K and Ohno H
J. Immunol. 188 2427 - 2436 2012年01月
共著, 査読有り
-
The Epithelia-specific membrane trafficking factor AP-1B controls gut immune homeostasis in mice.
Takahashi D, *Hase K , Kimura S, Nakatsu F, Ohmae M, Mandai Y, Sato T, Date Y, Ebisawa M, Kato T, Obata Y, Fukuda S, Kawamura Y, I, Dohi T, Katsuno T, Yokosuka O, Waguri S and Ohno H.
Gastroenterology 141 621-632 2011年12月
研究論文(学術雑誌), 共著, 査読有り
-
Bifidobacteria protect host from enteropathogenic infection through production of acetate.
Fukuda S, Toh H, Hase K, Oshima K, Nakanishi Y, Yoshimura K, Tobe T, Clarke JM, Topping DM, Suzuki T, Taylor TD, Itoh K, Kikuchi J, Morita H, *Hattori M, *Ohno H.
Nature 469 543-547 2011年12月
研究論文(学術雑誌), 共著, 査読有り
-
Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response.
Hase K, Kawano K, Nochi T, Pontes GS, Fukuda S, Ebisawa M, Kadokura K, Tobe T, Fujimura Y, Kawano S, Yabashi A, Waguri S, Nakato G, Kimura S, Murakami T, Iimura M, Hamura K, Fukuoka S, Lowe AW, Itoh K, Kiyono H, *Ohno H.
Nature 462 226-230 2009年12月
研究論文(学術雑誌), 共著, 査読有り
-
M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex.
Hase K, Kimura S, Takatsu H, Ohmae M, Kawano S, Kitamura H, Ito M, Watarai H, Hazelett CC, Yeaman C and *Ohno H.
Nat Cell Biol 11 1427-1432 2009年12月
研究論文(学術雑誌), 共著, 査読有り