論文 - 多胡 めぐみ
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STAT5 activation is critical for the transformation mediated by myeloproliferative disorder-associated JAK2 V617F mutant.
Funakoshi-Tago M, Tago K, Abe M, Sonoda Y, Kasahara T.
J Biol Chem. 285 ( 8 ) 5296-5307 2010年02月
研究論文(学術雑誌), 共著, 査読有り
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Proteolipid protein 2 is associated with melanoma metastasis.
Sonoda Y*,Warita M, Suzuki T, Ozawa H, Fukuda Y, Funakoshi-Tago M, Kasahara T.
Oncol Rep 23 (2) 371-376 2010年02月
研究論文(学術雑誌), 共著, 査読有り
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Pyrrolidinium-type fullerene derivative-induced apoptosis by the generation of reactive oxygen species in HL-60 cells.
Nishizawa C, Hashimoto N, Yokoo S, Funakoshi-Tago M, Kasahara T, Takahashi K, Nakamura S, Mashino T*.
Free Radical Res 43(12) 1240-1247 2009年12月
研究論文(学術雑誌), 共著, 査読有り
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Licochalcone A potently inhibits tumor necrosis factor alpha-induced nuclear factor-kappaB activation through the direct inhibition of IkappaB kinase complex activation.
Funakoshi-Tago M, Tanabe S, Tago K, Itoh H, Mashino T, Sonoda Y, Kasahara T.
Mol Pharmacol. 76 ( 4 ) 745-753 2009年10月
研究論文(学術雑誌), 共著, 査読有り
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The polycythemia vera-associated Jak2 V617F mutant induces tumorigenesis in nude mice.
Abe M, Funakoshi-Tago M*, Tago K, Kamishimoto J, Aizu-Yokota E, Sonoda Y, Kasahara T.
Int Immunopharmacol 9(7-8) 870-877 2009年07月
研究論文(学術雑誌), 共著, 査読有り
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The acute lymphoblastic leukemia-associated Jak2 L611S mutant induces tumorigenesis in nude mice.
Funakoshi-Tago M*, Tago K, Sumi K, Abe M, Aizu-Yokota E, Oshio T, Sonoda Y, Kasahara T.
J Biol Chem 284(19) 12680-12690 2009年05月
研究論文(学術雑誌), 共著, 査読有り
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Licochalcone A significantly suppresses LPS signaling pathway through the inhibition of NF-kappaB p65 phosphorylation at serine 276.
Furusawa J, Funakoshi-Tago M, Tago K, Mashino T, Inoue H, Sonoda Y, Kasahara T.
Cell Signal. 21 ( 5 ) 778-785 2009年05月
研究論文(学術雑誌), 共著, 査読有り
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Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway.
Furusawa J, Funakoshi-Tago M*, Mashino T, Tago K, Inoue H, Sonoda Y, Kasahara T.
Int Immunopharmacol. 9(4) 499-507 2009年04月
研究論文(学術雑誌), 共著, 査読有り
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Dermatophagoides farinae extract induces severe atopic dermatitis in NC/Nga mice, which is effectively suppressed by the administration of tacrolimus ointment.
Oshio T, Sasaki Y, Funakoshi-Tago M, Aizu-Yokota E, Sonoda Y, Matsuoka H, Kasahara T.
Int Immunopharmacol. 9 ( 4 ) 403-411 2009年04月
研究論文(学術雑誌), 共著, 査読有り
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TRAF6 negatively regulates TNFalpha-induced NF-kappaB activation.
Funakoshi-Tago M, Kamada N, Shimizu T, Hashiguchi Y, Tago K, Sonoda Y, Kasahara T.
Cytokine. 45 ( 2 ) 72-79 2009年02月
研究論文(学術雑誌), 共著, 査読有り
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Licochalcone A significantly suppresses LPS signaling pathway through the inhibition of NF-kappaB p65 phosphorylation at serine 276.
Furusawa JI, Funakoshi-Tago M*, Tago K, Mashino T, Inoue H, Sonoda Y, Kasahara T.
Cell Signal 21(5) 778-785 2009年01月
研究論文(学術雑誌), 共著, 査読有り
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Licochalcone A is a potent inhibitor of TEL-Jak2-mediated transformation through the specific inhibition of Stat3 activation.
Funakoshi-Tago M*, Tago K, Nishizawa C, Takahashi K, Mashino T, Iwata S, Inoue H, Sonoda Y, Kasahara T.
Biochem Pharmacol 76(12) 1681-1693 2008年12月
研究論文(学術雑誌), 共著, 査読有り
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Negative regulation of Jak2 by its auto-phosphorylation at tyrosine 913 via the Epo signaling pathway.
Funakoshi-Tago M*, Tago K, Kasahara T, Parganas E, Ihle JN.
Cell Signal 20(11) 1995-2001 2008年11月
研究論文(学術雑誌), 共著, 査読有り
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Mutation of Y925F in focal adhesion kinase (FAK) suppresses melanoma cell proliferation and metastasis.
Kaneda T, Sonoda Y, Ando K, Suzuki T, Sasaki Y, Oshio T, tago M, Kasahara T.
Cancer lett 270 p354-61 2008年11月
研究論文(学術雑誌), 共著, 査読有り
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TRAF6 is a critical signal transducer in IL-33 signaling pathway.
Funakoshi-Tago M*, Tago K, Hayakawa M, Tominaga S-I, Ohshio T, Sonoda Y, Kasahara T.
Cell Signal 20(9) 1679-1686 2008年09月
研究論文(学術雑誌), 共著, 査読有り
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Celecoxib potently inhibits TNFalpha-induced nuclear translocation and activation of NF-kappaB.
Funakoshi-Tago M,Shimizu T,Tago K,Nakamura M,Itoh H,Sonoda Y,kasahara T.
Biochem Pharmacol 76(5) p662-71 2008年09月
研究論文(学術雑誌), 共著, 査読有り
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Jak2 FERM domain interaction with the erythropoietin receptor regulates Jak2 kinase activity.
Funakoshi-Tago M, Pelletier S, Moritake H, Parganas E, Ihle JN*.
Mol Cell Biol. 28(5) 1792-1801 2008年03月
研究論文(学術雑誌), 単著, 査読有り
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TNF-receptor associated factor 6-deficient fibroblast is sensitive to the TNF-α-induced cell death:Involvement of reactive oxygen species.
Ichikawa D,Funakoshi-Tago M,Aizu-Yokota E,Sonoda Y,Inoue J-I,Kasahara T.
Biochem Biophys Res Commun 351 93-98 2006年12月
研究論文(学術雑誌), 共著, 査読有り
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Two domains of the erythropoietin receptor are sufficient for Jak2 binding/activation and function.
Pelletier S, Gingras S, Funakoshi-Tago M, Howell S, Ihle JN*.
Mol Cell Biol. 26(22) 8527-38 2006年11月
研究論文(学術雑誌), 単著, 査読有り
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Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2.
Funakoshi-Tago M, Pelletier S, Matsuda T, Parganas E, Ihle JN*.
EMBO J. 25(20) 4763-72 2006年10月
研究論文(学術雑誌), 単著, 査読有り