KEIO RESEARCHERS INFORMATION SYSTEM

Books 【 Display / hide 】

Books 【 Display / hide 】

• 「アンサングシンデレラ」・「治療薬マニュアル」コラボ小冊子

  青森達, 医学書院, 2020

• 老年医学（上）-基礎・臨床研究の最新動向-

  青森達, 望月眞弓, 日本臨牀社, 2018

  Contact page： 347-353

• 早期臨床体験テキスト

  AOMORI Tohru, ネオメディカル, 2017

• 精神科領域におけるEBP. Progressive Pharmacist

  AOMORI Tohru, 2010

• 薬剤師による処方支援　ワルファリン投与における処方支援

  AOMORI Tohru, 医薬ジャーナル, 2008

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Papers 【 Display / hide 】

Papers 【 Display / hide 】

• Prognostic model of baseline medications plus neutrophil-to-lymphocyte ratio in patients with advanced non-small-cell lung cancer receiving first-line immune-platinum regimen: A multicenter retrospective study

  Nasu Izumi, Kondo Masahiro, Uozumi Ryuji, Takada Shinya, Nawata Shuichi, Iihara Hirotoshi, Okumura Yohei, Takemoto Masashi, Mino Kozo, Sasaki Tadanori, Hirose Chiemi, Aomori Tohru, Shimano Rena, Maeno Ken, Oizumi Satoshi, Kusumoto Sojiro, Ohno Yasushi, Ikemura Shinnosuke, Takai Daiya, Hara Azusa, Kawazoe Hitoshi, Nakamura Tomonori

  Journal of Cancer 14   676 - 688 2023

  Research paper (scientific journal), Joint Work, Accepted

• Chromatography columns packed with thermoresponsive-cationic-polymer-modified beads for therapeutic drug monitoring

  Nagase K., Takagi H., Nakada H., Ishikawa H., Nagata Y., Aomori T., Kanazawa H.

  Scientific Reports （Scientific Reports)  12 （ 1 ）  2022.12

  　View Summary

  Therapeutic drug monitoring, which is used to determine appropriate drug doses, is critical in pharmacological therapy. In this study, we developed thermoresponsive chromatography columns with various cationic properties for effective therapeutic drug monitoring. Thermoresponsive cationic copolymer poly(N-isopropylacrylamide-co–n-butyl methacrylate-co–N,N-dimethylaminopropyl acrylamide) (P(NIPAAm-co-BMA-co-DMAPAAm))-modified silica beads, which were used as the chromatographic stationary phase, were prepared by modifying the radical initiator of the silica beads, followed by radical polymerization. Characterization of the prepared silica beads demonstrated that thermoresponsive polymers with various cationic properties successfully modified the beads. The elution behavior of several steroids in the prepared bead-packed columns at various temperatures indicated that the optimal column operating temperature was 30 °C. Appropriate measurement conditions for 13 drugs were investigated by varying the cationic properties of the columns and the pH of the mobile phase. Drug concentrations in serum samples were determined using the developed columns and mobile phases with a suitable pH. Voriconazole concentrations in human serum samples were determined using the developed columns with all-aqueous mobile phases. We anticipate that the developed chromatography columns can be used for therapeutic drug monitoring because drug concentrations can be measured using all-aqueous mobile phases that are suitable in clinical settings.

  • Access to Document (DOI)

• 診療科間における情報共有を可能とした妊娠・授乳と薬相談業務の取組み

  鈴木靖奈, 三浦あす美, 滝澤詠美子, 杉谷綾佳, 西木美優, 川島沙織, 櫻井しおり, 潮田佳奈,玉川知鮎, 清宮啓介, 小谷宙, 山吉康子, 村松博, 青森達

  日本病院薬剤師会雑誌 58   408 - 415 2022.03

  Research paper (scientific journal), Joint Work, Last author, Accepted

• Chromatographic columns packed with thermoresponsive-cationic-polymer-modified beads for therapeutic drug monitoring

  Nagase Kenichi, Takagi Hikaru, Nakada Hideo, Ishikawa Haruki, Itoh Yoshiko, Aomori Tohru, Kanazawa Hideko

  Scientific Reports 12   12847 2022

  Research paper (scientific journal), Joint Work, Accepted

• Cancer genomic medicine in Japan and the roles of pharmacists

  Tohru Aomori, Hiroomi Sakurai, Hiroshi Nishihara

  Pharmacogenetics and Genomics （Pharmacogenetics and Genomics)  32 （ 6 ） 242 - 245 2022

  Research paper (scientific journal), Joint Work, Lead author, Last author, Accepted,  ISSN  17446872

  　View Summary

  Cancer genomic medicine (CGM) is a medical service that provides optimized treatment for each patient based on genes, biomarkers, environment, and lifestyle. In Japan, the approval of designed core hospitals for CGM started in 2017. In June 2019, two types of cancer gene panel tests became available in the national health insurance system, and CGM was socially implemented. While CGM is still in its infancy and there are some issues that need to be resolved, there are cases where the treatment has shown dramatic results. The present review highlights the CGM system in Japan, the issues it faces, and the role of pharmacists in this system. Pharmacogenetics and Genomics 32: 242–245 Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.

  • Access to Document (DOI)

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Papers, etc., Registered in KOARA 【 Display / hide 】

Papers, etc., Registered in KOARA 【 Display / hide 】

• A study of individual variation in the placebo effect : gene polymorphisms of chemical mediator in the brain and personality

  Aomori, Tōru

  科学研究費補助金研究成果報告書 2020

• Construction of a database of unapproved, contraindicated, and off-label use of pharmaceuticals using AI and its application to medical safety

  Aomori, Tohru

  学事振興資金研究成果実績報告書 （慶應義塾大学)  2019

• Effect of genetic polymorphisms of azathioprine-metabolizing enzymes on response to rheumatoid arthritis treatment

  Aomori, Toru

  科学研究費補助金研究成果報告書 2017

• Relationship between therapeutic effect/side effect of azathioprine in SLE patients and NUDT15 gene mutation

  Aomori, Toru

  学事振興資金研究成果実績報告書 （慶應義塾大学)  2017

• Clinical pharmacological study for proper use in combination with Japanese traditional medicine and western medicine

  Aomori, Toru

  科学研究費補助金研究成果報告書 2016

Reviews, Commentaries, etc. 【 Display / hide 】

Reviews, Commentaries, etc. 【 Display / hide 】

• Cancer genomic medicine in Japan and the roles of pharmacists

  Aomori Tohru, Sakurai Hiroomi, Nishihara Hiroshi

  Pharmacogenetics and Genomics  2022

  Article, review, commentary, editorial, etc. (scientific journal), Joint Work, Lead author, Corresponding author

• Genomic medicine from a team approach and the role of pharmacists

  Aomori T., Mochizuki M.

  Yakugaku Zasshi (Yakugaku Zasshi)  140 ( 5 ) 649 - 650 2020.05

  ISSN  00316903

  • Access to Document (DOI)

Presentations 【 Display / hide 】

Presentations 【 Display / hide 】

• リツキシマブ治療の運用変更による安全性の検証と外来投与時の点滴時間に与える影響

  櫻井洋臣, 奥村洋平, 笠井雄佑, 野々宮菜彌, 吉田加奈, 津田壮一郎, 村松博, 青森達, 大谷壽一

  日本薬学会第143年会, 

  2023.03

  , 

  Poster presentation

• 倒・転落と新規作用機序睡眠薬の関連性についてのシステマティックレビュー

  桑原里佳, 石川春樹, 鈴川真由, 井澤美苗, 望月眞弓, 青森達

  日本薬学会第143年会, 

  2023.03

  , 

  Poster presentation

• LM1010高速液体クロマトグラフとLC-MS/MS法によるボリコナゾール濃度測定値の比較検討

  木村枝里香, 石川春樹, 中田英夫, 木村元範, 袴田潤, 津田壮一郎, 早川智久, 井澤美苗, 望月眞弓, 青森達

  日本薬学会第143年会, 

  2023.03

  , 

  Poster presentation

• 抗ヒスタミン薬の鎮静作用に関する系統的レビューとメタ解析

  鈴川真由, 泉谷優佳, 藤井愛梨, 本間遥香, 山内乃衣, 石川春樹, 望月眞弓, 青森達

  日本薬学会第143年会, 

  2023.03

  , 

  Poster presentation

• 入院患者の転倒・転落のリスクに対する各種睡眠薬・抗不安薬の比較

  髙野有紀, 石川春樹, 井澤美苗, 望月眞弓, 藤澤大介, 青森達

  日本薬学会第143年会, 

  2023.03

  , 

  Poster presentation

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Research Projects of Competitive Funds, etc. 【 Display / hide 】

Research Projects of Competitive Funds, etc. 【 Display / hide 】

• AI を用いた医薬品の未承認・禁忌・適応外使用データベースの構築と医療安全への応用

  2019

  2019年度慶應義塾学事振興資金（個人研究）, 青森達, Research grant, Principal investigator

• 慢性呼吸器疾患治療の高度化と標準化に向けた吸入動作評価技術の開発研究

  2019

  日本医療研究開発機構研究費, 橋渡し研究戦略的推進プログラム, Research grant, Coinvestigator(s)

• 生活者にとって分かりやすい要指導・一般用医薬品添付文書の構成に関する研究

  2018

  -

  2020

  日本医療研究開発機構研究費, Commissioned ｒesearch, Coinvestigator(s)

• プラセボ効果の個体間変動要因：プラセボームとパーソナリティ解析による個別薬物療法

  2018

  -

  2020

  日本学術振興会科学研究費補助金, 基盤研究 (C), Research grant, Coinvestigator(s)

• ゲノム医療従事者の育成プログラム開発

  2018

  -

  2020

  日本医療研究開発機構研究費, Commissioned ｒesearch, Coinvestigator(s)

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Awards 【 Display / hide 】

Awards 【 Display / hide 】

• 優秀演題賞

  富永佳子, 青森達, 早川智久, 井澤美苗, 望月眞弓, 2018.10, 第7回日本くすりと糖尿病学会学術集会, 糖尿病患者の服薬アドヒアランス不良リスク推定モデルの作成と介入支援ツールの構築 －患者への個別化対応実践のために－.

  Type of Award： Award from Japanese society, conference, symposium, etc.

• 学生優秀発表賞

  富永佳子, 青森達, 早川智久, 望月眞弓, 2018.03, 日本薬学会第138年会,, 糖尿病患者におけるアドヒアランス影響因子に関する研究－内的要因としての病識に着目した探索的検討－

  Type of Award： Award from Japanese society, conference, symposium, etc.

• 優秀発表賞

  菊山史博, 鈴木小夜, 高木彰紀, 地引綾, 横山雄太, 青森達, 中村智徳, 2017.09, 第2回日本薬学教育学会大会, 薬学実務実習が実習生の専門知識（C1～C18）の定着及び新規構築に与える影響

  Type of Award： Award from Japanese society, conference, symposium, etc.

• 優秀ポスター発表賞

  羽田有里, 青森達, 坡下真大, 荒木拓也, 山本康次郎, 鈴木小夜, 地引綾, 中村智徳, 2015.09, 第59回日本薬学会関東支部大会, アプレピタントによる補助療法ががん化学療法の治療経過に与える影響

  Type of Award： Award from Japanese society, conference, symposium, etc.

• 第66回日本食道学会学術集会優秀ポスター演題賞(メディカルスタッフ)

  荒木聖美、長嶺 歩、青森 達、荒木拓也、飯塚恵子、田中成岳、浅尾高行、桑野博行、中村智徳、山本康次郎., 2012.06, 日本食道学会, 食道癌化学放射線療法における免疫栄養剤併用の有用性.

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Courses Taught 【 Display / hide 】

Courses Taught 【 Display / hide 】

• STUDY OF MAJOR FIELD: (HOSPITAL PHARMACY SCIENCE)

  2022

• SPECIALTY PHARMACISTS ACTIVE IN PERSONALIZED TREATMENT

  2022

• SEMINAR: (HOSPITAL PHARMACY SCIENCE)

  2022

• RESEARCH FOR BACHELOR'S THESIS 1

  2022

• PRIOR LEARNING FOR CLINICAL PRACTICE 4

  2022

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