Presentations -

アルコール肝障害と酸化ストレス

Katou Shinzou

第8回箱根シンポジウム, 

1998.07

Oxida tive stress on mitochondria and cell membrane of cultured rat heptocytes and perfused liver exposed to ethhanol

Ishii Hiromasa, Higuchi Hajime, Horie Yoshinori, Miura Souichiro, Kato Shinzo

Congress of the International Society for Biomedical Research on Alcoholism(9th; 1998), 

1998.06

Importance of NADPH reductase rather than NADPH oxidase as a source of superoxide anion that is released into hepatic sinusoid after ethanol challenge

Okamura Yukishige, Yokoyama Hirokazu, Fukuda Masahiko, Ohgo Hideki, Matsumoto Michinaga, Nakamura Yuji, Kato Shinzo, Ishii Hiromasa

Congress of the International Society for Biomedical Research on Alcoholism(9th; 1998), 

1998.06

Ethanol ingestion damages in testinal epithelium and enhances the absorption of lipopolysaccharide(LPS) in rat

Tamai Hironao, Kato Shinzo, Ohgo Hideki, Yokoyama Hirokaziu, Fukuda Masahiko, Matsumoto Michinaga, Okamura Yukishige, Nakamura Yuji, Ishii Hiromasa

Congress of the International Society for Biomedical Research on Alcoholism(9th; 1998), 

1998.06

Ethanol-induced oxidative stress and liver injury: Modification by nitric oxide

Horie Yoshinori, Ishii Hiromasa, Higuchi Hajime, Adachi Masayuki, Yokoyama Hirokazu, Miura Souichiro, Kato Shinzo

Congress of the International Society for Biomedical Research on Alcoholism(9th; 1998), 

1998.06

Evidence for partictpation of P450 2E1, NADPH reductase and catalase in ethalnol oxidation by kupffer cells

Nakamura Yuji, Yokoyama Hirokazu, Okamura Yukishige, Ohgo Hideki, Matsumoto Michinaga, Horie Yoshinori, Kato Shinzo, Ito Daisuke, Ishii Hiromasa

Congress of the International Society for Biomedical Research on Alcoholism(9th; 1998), 

1998.06

Reduced form glutathione (GSH) but not oxiidized one (GSSG) suppresses the level of superoxide anion(SO) that is released into hepapatic sinusoid after ethanol challenge

Ohgo Hideki, Yokoyama Hirokazu, Okamura Yukishige, Fukuda Masahiko, Mizukami Takeshi, Ito Daisuke, Horie Yoshinori, Kato Shinzo, Ishii Hiromasa

Congress of the International Society for Biomedical Research on Alcoholism(9th; 1998), 

1998.06

Hepatic microvascular dysfunction in endtoxemic rats after acute ethanol administration

Horie Yoshinori, Kato Shinzo, Okamura Yukishige, Ohgo Hideki, Matsumoto Michinaga, Nakamura Yuji, Suzuki Hidekazu, Yokoyama Hidekazu, Miura Souichiro, Ishii Hiromasa

Congress of the International Society for Biomedical Research on Alcoholism(9th; 1998), 

1998.06

Molecular mechanisms of peroxisome proliferation by peroxisome proliferator (Bezafibrate) in Kupffer cell

Nakamura Yuji, Yokoyama Hirokazu, Ito Daisuke, Kamegaya Nobutaka, Okamura Yukishige, Ohgo Hideki, Matsumoto Michinaga, Fukuda Masahiko, Mizukami Takeshi, Kato Shinzo, Ishii Hirokazu

Annual Meeting of the American Gastroenterological Association(98th; 1998; New Orleans), 

1998.05

Evidence for involvement of NADPH reductase in the formation of superoxide anion released into hepatic sinusoid

Okamura Yukishige, Yokoyama Hidekazu, Fukuda Masahiko, Mizukami Takeshi, Ohgo Hideki, Matsumoto Michinaga, Nakamura Yuji, Ito Daisuke, Tomita Kengo, Kato Sinzo, Ishii Hiromasa

Annual Meeting of the American Gastroenterological Association(98th; 1998; New Orleans), 

1998.05

肝細胞癌患者血清VEGF, HGF値の肝動脈塞栓前後の変動

Suzuki Hidekazu, Mori Mikiji, Adachi Masayuki, Saitou Hidetsugu, Katou Shinzou, Oda Masaya, Miura Souichirou, Hibi Toshifumi, Ishii Hiromasa

第95回日本内科学会講演会, 

1998.04

Helicobacter pylori感染がヒト胃粘膜のクラス・アルコール脱水素酵素活性におよぼす影響

Matsumoto Michinaga, Yokoyama Hidekazu, Okamura Yukishige, Oogo Hideki, Nakamura Yuuji, Mori Mikiji, Suzuki Hidekazu, Itou Daisuke, Katou Shinzou, Ishii Hiromasa

第84回消化器病総会, 

1998.04

抗LFA-1抗体，抗ICAM-1抗体の投与におけるTNF-αが惹起する肝類洞での活性酸素産生の抑制

Oogo Hideki, Yokoyama Hirokazu, Fukuda Masahiko, Okamura Yukishige, Mizukami Takeshi, Matsumoto Michinaga, Nakamura Yuuji, Katou Shinzou, Itou Daisuke, Ishii Hiromasa

第34回肝臓病学会, 

1998.04

BEZAFIBRATEによるエタノール急性負荷により肝類洞へ放出される活性酸素産生の抑制

Okamura Yukishige, Yokoyama Hirokazu, Itoudaisuke, Nakamura Yuuji, Oogo Hideki, Matsumoto Michinaga, Katou Shinzou, Ishii Hiromasa

第34回肝臓病学会, 

1998.04

クッパー細胞のエタノール代謝の検討--Cytochrome P450 2E1 の関与

Nakamura Yuuji, Yokoyama Hirokazu, Okamura Yukishige, Katou Shinzou, Ishii Hiromasa

第18回アルコール医学生物学研究会, 

1998.03

エタノール投与により肝類洞に放出される活性酸素に対するグルタチオンの影響

Yokoyama Hirokazu, Moriya Susumu, Okamura Yukishige, Katou Shinzou, Ishii Hiromasa

第18回アルコール医学生物学研究会, 

1998.03

エタノール投与により肝類洞に放出される活性酸素の産生機序の検討

Okamura Yukishige, Yokoyama Hirokazu, Mizukami Takeshi, Katou Shinzou, Ishii Hiromasa

第18回アルコール医学生物学研究会, 

1998.03

von Recklinghausen病に小腸平滑筋肉腫を合併し，大量下血をきたした1例

Masaoka Tatehiro, Mizumori Misa, Matsumoto Michinaga, Iwao Yasushi, Katou Shinzou, Miura Souichirou, Hibi Toshifumi, Ishii Hiromasa, Watanabe Masahiko, Takahashi Shin

第247回日本消化器病学会 関東支部例会, 

1997.12

von Recklinghausen病に小腸STromal cell Tumorを合併した1例

Masaoka Tatehiro, Mizumori Misa, Matsumoto Michinaga, Iwao Yasushi, Katou Shinzou, Miura Souichirou, Hibi Toshifumi, Ishii Hiromasa, Watanabe Masahiko, Takahashi Shin

第247回日本消化器病学会関東支部例会, 

1997.12

A peroxisome proliferator (bezafiblate) can prevent superoxide anion release into hepatic sinusoid after acute ethanol administration

Okamura Yukisige, Yokoyama Hirokazu, Ito Daisuke, Kato Shinzo, Ishii Hiromasa

Annual Meeting of the American Association for the Study of Liver Disease (48th; 1997), 

1997.11