Reviews, Commentaries, etc. - Soga, Tomoyoshi

腫瘍における分岐鎖アミノ酸トランスポーターの役割

Saito, Y., Soga, T.

Experimental Medicine (YODOSHA)  40 ( 14 ) 2239 - 2244 2022.08

Article, review, commentary, editorial, etc. (other), Joint Work

アミノ酸トランスポーターを標的とした個別化医療

Precision Medicine 4 ( 13 ) 18 - 22 2021.11

Article, review, commentary, editorial, etc. (other), Joint Work

メタボロミクスによるがん幹細胞の代謝研究

北島正二朗、曽我朋義

（別冊 医学のあゆみ）　治療標的としてのがん幹細胞 (Ishiyaku Pub,Inc.)     117 - 121 2021.03

Article, review, commentary, editorial, etc. (other), Joint Work

メタボローム解析に基づく癌診断法の開発

Soga, T., Sugimoto, M.

Gastroenterology & Hepatology (Kagakuhyoronsya Co., Ltd.)  8 ( 2 ) 137 - 143 2020.08

Joint Work

はじめに-メタボローム解析UPDATE

Soga, T.

（別冊・医学のあゆみ） メタボローム解析UPDATE (Ishiyaku Pub,Inc.)   2020.06

Single Work

メタボロミクスによるがん幹細胞の代謝研究

Kitajima, S., Soga, T.

Journal of Clinical and Experimental Medicine（IGAKU NO AYUMI） (Ishiyaku Pub,Inc.)  273 ( 5 ) 469 - 473 2020.05

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

はじめに-メタボローム解析UPDATE

Soga, T.

Journal of Clinical and Experimental Medicine（IGAKU NO AYUMI） (Ishiyaku Pub,Inc.)  270 ( 5 ) 377 - - 2019.08

Article, review, commentary, editorial, etc. (scientific journal)

どこまで使える？ メタボローム解析ー汎用化と高感度化の近未来をうらなう

モデレーター 曽我朋義、パネリスト 馬場健史、杉本昌弘、三枝大輔、平山明由、石川貴正

Experimental Medicine (Yodosha)  36 ( 19 ) 3294 - 3301 2018.11

Article, review, commentary, editorial, etc. (scientific journal)

　View Summary

Next Tech Review 特別編

がん代謝の分子メカニズム

Soga, T.

The Japanese journal of Clinical Nutrition (Ishiyaku Pub,Inc.)  133 ( 6 ) 844 - 846 2018.11

Article, review, commentary, editorial, etc. (scientific journal), Single Work

がん代謝

Soga, T.

Experimental Medicine (Yodosha)  36 ( 15 ) 114 - 120 2018.09

Article, review, commentary, editorial, etc. (scientific journal), Single Work

MYCはがん代謝のマスターレギュレーターである

Satoh, K., Soga, T.

Experimental Medicine (Yodosha)  36 ( 4 ) 514 - 521 2018.03

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

オンコメタボライト：フマル酸による癌代謝と遺伝子制御

Soga, T.

The Lipid (Medical Review Co.,Ltd)  28 ( 3 ) 75(291) - 82(298) 2017.07

Article, review, commentary, editorial, etc. (scientific journal), Single Work

序にかえて―ワールブルグを超えて

Soga, T.

Experimental Medicine (Yodosha)  35 ( 10 ) 3(1557) - 9(1563) 2017.06

Article, review, commentary, editorial, etc. (scientific journal), Single Work

メタボロミクスによるがんの代謝解析

Hirayama, A., Soga, T.

Experimental Medicine (Yodosha)  35 ( 10 ) 206(1760) - 210(1764) 2017.06

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

フマル酸―フマル酸によるさまざまな代謝調節機構

Soga, T.

Experimental Medicine (Yodosha)  35 ( 10 ) 134(1688) - 141(1695) 2017.06

Article, review, commentary, editorial, etc. (scientific journal), Single Work

CE-MSメタボロミクスとがん研究

Soga, T.

Electrophoresis Letters (The Japanese Electrophoresis Society)  59 ( 2 ) 67 - 69 2015.10

• Access to Document (DOI)

Comprehensive Analysis of Microbes and Metabolites in Human Tear Fluids

Murakami, S., Baba, F., Aw, W., Fukuda, S., Soga, T., Fujishima, H., Tomita, M.

KEIO SFC JOURNAL （Advanced Bioscience Studies at SFC: Our Grand Challenges to Save the World） (KEIO University Shonan Fujisawa Gakkai)  15 ( 1 ) 382 - 400 2015.09

Article, review, commentary, editorial, etc. (scientific journal)

メタボロームが解き明かす生命のシステム

Soga, T., Hirayama, A., Sugimoto, M.

KEIO SFC JOURNAL (Advanced Bioscience Studies at SFC: Our Grand Challenges to Save the World) (KEIO University Shonan Fujisawa Gakkai)  15 ( 1 ) 64 - 75 2015.09

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

唾液検査でがんを、血液検査でうつ病を検出

Takato, M., Sugimoto, M., Soga, T., Tomita, M.

Journal of the Japan Pharmaceutical Association (Japan Pharmaceutical Association)  67 ( 8 ) 15(1145) - 8(1148) 2015.08

Article, review, commentary, editorial, etc. (scientific journal)

心筋症のメタボロミクス

HIrayama, A., Soga, T.

Journal of Clinical and Experimental Medicine（IGAKU NO AYUMI） (Ishiyaku Pub,Inc.)  252 ( 10 ) 1021 - 1026 2015.03

Article, review, commentary, editorial, etc. (scientific journal)

メタボロミクス

HIrayama, A., Soga, T.

Seitai No Kagaku (The Ichiro Kanehara Foundation/ Igaku-Shoin Ltd.)  65 ( 5 ) 408 - 409 2014.10

Article, review, commentary, editorial, etc. (scientific journal)

がん細胞はなぜ解糖系？－がん細胞の代謝

Soga, T.

Experimental Medicine (Yodosha)  32 ( 15 ) 72 (2404) - 77(2409) 2014.09

Article, review, commentary, editorial, etc. (scientific journal)

メタボローム（メタボロミクス）

Hirayama, A., Soga, T.

Journal of Clinical and Experimental Medicine（IGAKU NO AYUMI） (Ishiyaku Pub,Inc.)  249 ( 5 ) 378 - 378 2014.05

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

はじめに-メタボローム解析の進歩

Soga, T.

Journal of Clinical and Experimental Medicine（IGAKU NO AYUMI） (Ishiyaku Pub,Inc.)  249 ( 4 ) 285 - 285 2014.04

Article, review, commentary, editorial, etc. (scientific journal)

メタボローム解析技術とがんの代謝解析への応用

Hirayama, A., Soga, T.

Experimental Medicine (Yodosha)  32 ( 8 ) 1205 - 1209 2014.04

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

総論　がんとメタボローム：オーバービュー

Soga, T.

The CELL (NEW SCIENCE co., ltd.)  46 ( 3 ) 2(104) - 4(105) 2014.02

Article, review, commentary, editorial, etc. (scientific journal), Single Work

オンコメタボライト-フマル酸によるがんの代謝制御

Soga, T.

CELL TECHNOLOGY (Gakken Medical Shujunsha Co.,Ltd.)  33 ( 2 ) 133 - 138 2014.01

Article, review, commentary, editorial, etc. (scientific journal), Single Work

がんの代謝 : ワールブルク効果の今日的な解釈

Soga, T.

CLINICAL ONCOLOGY (Kagakuhyoronsya Co., Ltd. )  11 ( 6 ) 717 - 724 2013.06

Article, review, commentary, editorial, etc. (scientific journal), Single Work

メタボロミクスによるがんの診断マーカー探索

Soga, T.

CHEMISTRY TODAY (Tokyo Kagaku Dojin)  504 ( 3 ) 52 - 56 2013.02

Article, review, commentary, editorial, etc. (scientific journal), Single Work

がんの代謝研究の最前線-Warburgを超えて

Soga, T.

Experimental Medicine (Yodosha)  30 ( 15 ) 12(2346) - 22(2356) 2012.09

Article, review, commentary, editorial, etc. (scientific journal), Single Work,  ISSN  0288-5514

メタボローム解析によるがんの代謝解析

Hirayama, A., Soga, T.

Experimental Medicine (Yodosha)  30 ( 15 ) 203(2537) - 208(2542) 2012.09

Article, review, commentary, editorial, etc. (scientific journal), Joint Work,  ISSN  0288-5514

メタボローム解析によるがんのフマル酸呼吸の解明

Kami, K., Tomitsuka, E., Sakai, C., Kita, K., Esumi, H., Soga, T.

Experimental Medicine (Yodosha)  30 ( 15 ) 73(2407) - 80(2414) 2012.09

Article, review, commentary, editorial, etc. (scientific journal), Joint Work,  ISSN  0288-5514

メタボロミクスによる家族性大腸腺腫症の脂質ダイナミクス探索

Ikeda, K., Soga, T.

BIO Clinica (Hokuryukan)  27 ( 7 ) 29 - 33 2012.07

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

新たな局在グライコリピドミクス技術によるマウス脳の加齢過程でのスフィンゴ糖脂質の分子種分布解析

Ikeda, K., Taguchi, R., Soga, T.

JSBMS Lett (Japanese Society for Biomedical Mass Spectrometry)  37 ( 2 ) 22 - 30 2012.06

Article, review, commentary, editorial, etc. (scientific journal), Joint Work,  ISSN  1881-5464

がん組織に特異的な代謝変化

Hirayama, A., Soga, T.

Journal of Clinical and Experimental Medicine（IGAKU NO AYUMI） (Ishiyaku Pub,Inc.)  241 ( 6 ) 445 - 449 2012.05

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

メタボローム解析に基づくがん特異的代謝の解明

Hirayama, A., Soga, T.

Experimental Medicine (Yodosha)  30 ( 7 ) 25(1043) - 30(1048) 2012.04

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

メタボロームと糖尿病

Yamashita, R., Soga, T., Kaburagi, Y.

The Medical Frontline (Saishin-igaku.co.jp)  67 ( 1 ) 39 - 43 2012.01

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

CE-MSメタボローム測定法

Hirayama, A., Soga, T.

Diabetes Frontier (Medical Review Co., Ltd.)  22 ( 6 ) 673 - 678 2011.12

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

新規酸化ストレスマーカーγ-グルタミルジペプチドによる肝疾患スクリーニング

Soga, T.

酸化ストレスと肝疾患 (Medical Tribune, Inc.)  7   115 - 123 2011.08

Article, review, commentary, editorial, etc. (scientific journal), Single Work

CE-MS法によるメタボローム解析と医薬への応用

Soga, T.

(遺伝子医学MOOK19) トランスポートソーム　生体膜輸送機構の全体像に迫る (Medical Do, Co., Ltd.)     66 - 70 2011.03

Article, review, commentary, editorial, etc. (scientific journal), Single Work

CE-MSメタボロミクス

Hirayama, A., Soga, T.

HORMONE FRONTIER IN GYNECOLOGY (Medical Review Co., Ltd.)  18 ( 1 ) 19 - 25 2011.03

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

メタボローム解析による癌代謝特性の包括的解明

Hirayama, A., Soga, T.

CELL TECHNOLOGY (Gakken Medical Shujunsha Co.,Ltd.)  30 ( 1 ) 25 - 29 2010.12

Article, review, commentary, editorial, etc. (scientific journal), Joint Work,  ISSN  0287-3796

CE-MSメタボロミクスの最新動向

Soga, T.

Bunseki (The Japan Society Analytical Chemistry)  461 ( 11 ) 585 - 590 2010.11

Article, review, commentary, editorial, etc. (scientific journal), Single Work,  ISSN  0386-2178

がん組織のメタボローム解析

Hirayama, A., Soga, T.

BIO INDUSTRY (CMC Publishing Co.,Ltd.)  27 ( 3 ) 50 - 56 2010.03

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

ヒト癌組織のメタボローム解析

Hirayama, A., Soga, T.

Journal of Clinical and Experimental Medicine（IGAKU NO AYUMI） (Ishiyaku Pub,Inc.)  231 ( 12,13 ) 1145 - 1149 2009.12

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

はじめに-メタボロミクスー網羅的代謝物質解析の医学・医療へのあらなた応用

Soga, T.

Journal of Clinical and Experimental Medicine（IGAKU NO AYUMI） (Ishiyaku Pub,Inc.)  231 ( 12,13 ) 1143 2009.12

Article, review, commentary, editorial, etc. (scientific journal), Single Work

メタボローム測定装置の発明

Soga, T.

The Invention (Japan Institute of Invention And Innovation)  106 ( 11 ) 29 - 31 2009.11

Article, review, commentary, editorial, etc. (scientific journal), Single Work

メタボローム解析による癌微小環境のエネルギー代謝の解明

Kami, K., Tomitsuka,E., Tomita, M., KIta, K., Esumi, H., Soga, T.

Experimental Medicine (Yodosha)  27 ( 2 ) 215 - 221 2009.01

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

最新のメタボローム測定法の開発と生命科学への応用

Soga, T.

(化学フロンティア20) 新しい地平をひらく分析手法の最前線 (Kagaku-Dojin Publishing Company,INC)     21 - 28 2009.01

Article, review, commentary, editorial, etc. (scientific journal), Single Work

Cancer Metabolomics: Toward the Development of Novel Anticancer Therapeutics Targeting the Energy Metabolism in Tumor Microenvironment

Kami, K., Tomitsuka, E., Kita, K., Tomia, M., Soga, T., Esumi, H.,

臨床化学　 (Japan Society of Clinical Chemistry)  37 ( 4 ) 361 - 367 2008.10

Article, review, commentary, editorial, etc. (scientific journal), Single Work

Metabolome Analysis by CE-MS and Application to Biosciences

soga, T.

臨床化学　 (Japan Society of Clinical Chemistry)  37 ( 4 ) 341 - 346 2008.10

Article, review, commentary, editorial, etc. (scientific journal), Single Work,  ISSN  0370-5633

細菌のマルチオミクス(各種網羅的測定データ)解析の最先端

Ishi, N., Soga, T., Tomita, M.

化学と生物 (Japan Society for Bioscience, Biotechnology, and Agrochemistry)  46 ( 4 ) 228 - 229 2008.04

Article, review, commentary, editorial, etc. (scientific journal), Joint Work,  ISSN  0453-073X

代謝シミュレーションとメタボローム解析による赤血球低酸素応答の予測と実証

Yachie-Kinoshita, A., Suematsu, M., Soga, T., Tomita, M.

Experimental Medicine (Yodosha)  26 ( 1 ) 7 - 12 2007.12

Article, review, commentary, editorial, etc. (scientific journal), Joint Work,  ISSN  0288-5514

トランスクリプトーム,プロテオーム,メタボローム,フラクソームの統合による大腸菌の代謝解明

Ishii, Y., Soga, T., Tomita, M.

Experimental Medicine (Yodosha)  26 ( 1 ) 24 - 29 2007.12

Article, review, commentary, editorial, etc. (scientific journal), Joint Work,  ISSN  0288-5514

概論-メタボロ－ムが解き明かす生命のシステム

Soga, T.

Experimental Medicine (Yodosha)  26 ( 1 ) 7 - 12 2007.12

Article, review, commentary, editorial, etc. (scientific journal)

メタボロミクスの医学への応用

Soga, T., Ohashi, Y., Tomita, M.

The Medical Frontline (Saishin-igaku.co.jp)  62 ( 9月増刊 ) 55(2040) - 63(2047) 2007.09

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

メタボロ－ム解析技術の医学、生物学への応用

Suematsu, M., Omura, M., Onoe, M., Hishiki, T., Soga, T.

Experimental Medicine (Yodosha)  25 ( 15 ) 154(2364) - 161(2391) 2007.09

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

CE/MSによるメタボローム測定法とバイオマーカーの探索

Soga, T.

(細胞工学別冊) 最新 プロテオミクス・メタボロミクス (Shujunsha)     137 - 145 2007.07

Article, review, commentary, editorial, etc. (scientific journal), Single Work

CE-MSによるメタボローム解析とバイオマーカーの探索

Soga, T.

CELL TECHNOLOGY (Shujunsha )  25 ( 12 ) 1381 - 1387 2006.11

Article, review, commentary, editorial, etc. (scientific journal), Single Work

CE-MSによる微生物メタボロミクス

Ohashi, Y., Soga, T.

Seibutsu-kogaku Kaishi (The Society for Biotechnology, Japan)  84 ( 6 ) 223 - 226 2006.06

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

肝炎のバイオマーカーを発見

Soga, T.

BTJジャーナル (Nikkei Business Publications, Inc.)   ( 5 ) 3 - 5 2006.05

Article, review, commentary, editorial, etc. (scientific journal), Single Work

Metabolomics：System for genome interacting with environments through chemical substances

Nishioka, T., Terabe, S., Soga, T., Matsuda, K., Fujita, Y.

PROTEIN, NUCLEIC ACID AND ENZYME (KYORITSU SHUPPAN )  50 ( 16 ) 2198 - 2203 2005.12

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

赤血球代謝の低酸素応答とその生理機能の解明にむけて-メタボロ－ム解析と細胞シミュレーションによるアプローチ

Kinoshita, A., Nakayama, Y., Soga, T., Tomita, M. Suematsu, M.

Vascular Biology & Medicine (Medical Review Co.,Ltd.)  6 ( 6 ) 83 - 90 2005.12

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

CE-MSを用いたメタボローム測定へのアプローチ

Soga, T., Kakazu, Y.

Farumashia (The Pharmaceutical Society of Japan)  41 ( 11 ) 1053 - 1058 2005.11

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

メタボロ－ム解析技術と創薬研究への応用

Ohkishi, H., Soga, T., Tomita, M.

Molecular Medicine (Nakayama Shoten)  42 ( 11 ) 1249 - 1256 2005.10

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

CE-MSを用いたメタボローム解析

Nishioka, T., Soga, T.

JOURNAL OF MEDICAL TECHNOLOGY (Igaku-Shoin Ltd.)  49 ( 9 ) 1015 - 1020 2005.09

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

CE-MSによるメタボロームの測定および同定

Soga, T., Kakazu, Y.

MEDCHEM NEWS (Division of Medicinal Chemistry, The Pharmaceutical Society of Japan)  15 ( 3 ) 15 - 17 2005.08

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

メタボロ－ム解析の進展と創薬への応用

Ohkishi, H., Soga, T., Tomita, M.

Experimental Medicine (Yodosha)  23 ( 4 ) 141 - 148 2005.02

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

LC/イオントラップMSによる大腸菌メタボローム解析システムの開発

Kato, N., Soga, T.

Bunseki (The Japan Society Analytical Chemistry)   ( 11 ) 658 - 660 2004.11

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

メタボロミクス解析システム

Suzuki, H., Awazuhara, M., Soga, T., Yamazaki, Y., Saito, K.

PROTEIN, NUCLEIC ACID AND ENZYME (KYORITSU SHUPPAN CO., LTD.)  49 ( 11 ) 1893 - 1899 2004.08

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

メタボロミクスの現状と展望

Saito, K., Soga, T., Tomita, M., Fukusaki, E.,

BIOINDUSTRY (CMC Publishing Co.,Ltd.)   ( 7 ) 6 - 18 2004.06

Article, review, commentary, editorial, etc. (scientific journal), Joint Work

ダイナミックな生命現象のメタボローム解析技術

Soga, T., Sato, S., Nishioka, T.

CELL TECHNOLOGY (Shujunsha)  22 ( 12 ) 1337 - 1341 2003.12

Article, review, commentary, editorial, etc. (scientific journal), Joint Work,  ISSN  02873796

CE-MSによるメタボローム解析

Soga, T.

Inflammation & Immunity (SENTAN IGAKU-SHA)  11 ( 6 ) 690 - 699 2003.10

Article, review, commentary, editorial, etc. (scientific journal), Single Work

メタボローム解析-代謝物質の網羅的化学分析法の開発

Ueno, Y., Soga, T., Tomita, M.

Journal of Clinical and Experimental Medicine（IGAKU NO AYUMI） (Ishiyaku Pub,Inc.)  206 ( 3 ) 226 - 227 2003.07

Article, review, commentary, editorial, etc. (scientific journal), Joint Work,  ISSN  0039-2359

キャピラリー電気泳動による無機陰イオン、有機酸、アミノ酸および糖の一斉分析法

Soga, T.

Bunseki (The Japan Society Analytical Chemistry)   ( 9 ) 454 - 459 2001.09

Article, review, commentary, editorial, etc. (scientific journal), Single Work

　View Summary

キャピラリー電気泳動による無機陰イオン、有機酸、アミノ酸および糖類の一斉分析方法を開発し、測定原理、応用例を解説した。

Study on simultaneous determination methods for anions by capillary electrophoresis.

Soga, T.

BUNSEKI KAGAKU (The Japan Society Analytical Chemistry)  49 ( 8 ) 645 - 646 2000.08

Article, review, commentary, editorial, etc. (scientific journal), Single Work,  ISSN  0525-1931

キャピラリー電気泳動による無機陰イオン,有機酸,アミノ酸および糖の一斉分析法

Soga, T.

Seibutsu-kogaku Kaishi (The Society for Biotechnology, Japan)  78 ( 5 ) 174 - 175 2000.05

Article, review, commentary, editorial, etc. (scientific journal), Single Work,  ISSN  0919-3758

Analysis of various organic acids in silage using capillary electrophoresis method.

Ishiguro, E., Hibino, H., Soga, T., Yanai, H., Sawada, H.

Animal-husbandry (YOKENDO)  54 ( 5 ) 588 - 590 2000.05

Article, review, commentary, editorial, etc. (scientific journal), Joint Work,  ISSN  0009-3874

New Method for Sugar Analysis Using HPLC

Soga, T.

A technical journal on food chemistry & chemicals (FOOD CHEMICALS NEWSPAPER INC.)  7 ( 12 ) 44 - 48 1991.12

Article, review, commentary, editorial, etc. (scientific journal), Single Work,  ISSN  0911-2286

SGLT2 inhibition eliminates senescent cells and alleviates pathological aging

Katsuumi G., Shimizu I., Suda M., Yoshida Y., Furihata T., Joki Y., Hsiao C.L., Jiaqi L., Fujiki S., Abe M., Sugimoto M., Soga T., Minamino T.

Nature Aging (Nature Aging)   2024

　View Summary

It has been reported that accumulation of senescent cells in various tissues contributes to pathological aging and that elimination of senescent cells (senolysis) improves age-associated pathologies. Here, we demonstrate that inhibition of sodium–glucose co-transporter 2 (SGLT2) enhances clearance of senescent cells, thereby ameliorating age-associated phenotypic changes. In a mouse model of dietary obesity, short-term treatment with the SGLT2 inhibitor canagliflozin reduced the senescence load in visceral adipose tissue and improved adipose tissue inflammation and metabolic dysfunction, but normalization of plasma glucose by insulin treatment had no effect on senescent cells. Canagliflozin extended the lifespan of mice with premature aging even when treatment was started in middle age. Metabolomic analyses revealed that short-term treatment with canagliflozin upregulated 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside, enhancing immune-mediated clearance of senescent cells by downregulating expression of programmed cell death-ligand 1. These findings suggest that inhibition of SGLT2 has an indirect senolytic effect by enhancing endogenous immunosurveillance of senescent cells.

• Access to Document (DOI)