Watanabe, Mitsuhiro

写真a

Affiliation

Graduate School of Media and Governance (Shonan Fujisawa)

Position

Professor

E-mail Address

E-mail address

Other Affiliation 【 Display / hide

  • Faculty of Environment and Information Studies

  • School of Medicine

Career 【 Display / hide

  • 1992.04
    -
    2001.09

    三菱化成(株) 現(株)三菱ケミカルホールディングス, 応用生物学研究所 医薬第一研究所, 主任研究員

  • 2001.10
    -
    Present

    東邦大学, 医学部生理学講座, 研究生

  • 2002
    -
    Present

    独立行政法人 , 国立健康・栄養研究所, 協力研究員

  • 2004.05
    -
    2004.08

    Harvard Medical School, 客員研究員

  • 2004.05
    -
    2006.09

    フランス国立科学研究所 分子遺伝細胞生物学研究所, 研究員

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Academic Background 【 Display / hide

  • 1990.04
    -
    1992.04

    東北大学, 遺伝子実験施設  

    Graduate School, Graduated, Master's course

  • 2001.09
    -
    2004.05

    フランス国立ルイパスツール大学 , 分子生物学科

    Graduate School, Graduated, Doctoral course

Academic Degrees 【 Display / hide

  • 農学修士, 東北大学, 1992.04

  • Ph.D., フランス国立ルイ パスツール大学, 2004.05

 

Research Areas 【 Display / hide

  • Molecular biology (メタボリックシンドローム)

  • Molecular biology (肥満:脂質代謝:糖代謝)

  • Molecular biology (抗老化医学)

  • Molecular biology (予防医学)

  • Molecular biology (栄養医学)

 

Books 【 Display / hide

  • 糖尿病に効く!胆汁酸健康法-肥満を解消し、血糖値を下げる!!

    Watanabe Mitsuhiro, 洋泉社, 2013.12

  • レズベラトロールの基礎と応用

    Watanabe Mitsuhiro, シーエムシー出版, 2012.09

  • 老化・老年病研究のための動物実験ガイドブック

    Watanabe Mitsuhiro, 株式会社アドスリー, 2008.05

  • 肥満と脂肪エネルギー代謝

    Watanabe Mitsuhiro, 建帛社, 2008.04

Papers 【 Display / hide

  • Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation.

    Watanabe Mitsuhiro

    Nature 439   484 - 489 2006

    Accepted

  • Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c.

    Watanabe Mitsuhiro

    J Clin Invest 113   1408 - 1418 2004

    Joint Work, Accepted

  • Lowering Bile Acid Pool Size with a Synthetic Farnesoid X Receptor (FXR) Agonist Induces Obesity and Diabetes through Reduced Energy Expenditure.

    Watanabe Mitsuhiro, Horai Yasushi, Houten Sander M., Morimoto Kohkichi, Sugizaki Taichi, Arita Eri, Mataki Chikage, Sato Hiroyuki, Tanigawara Yusuke, Schoonjans Kristina, Itoh Hiroshi, Auwerx Johan

    Journal of Biological Chemistry 286 ( 30 ) 26913-26920 2011.07

    Research paper (scientific journal), Joint Work, Accepted

  • Bile Acid Binding Resin Improves Metabolic Control through the Induction of Energy Expenditure

    Watanabe MitsuhiroMorimoto, Kohkichi ; Houten, Sander M. ; Kaneko-Iwasaki, Nao ; Sugizaki, Taichi ; Horai, Yasushi ; Mataki, Chikage ; Sato, Hiroyuki ; Murahashi, Karin ; Arita, Eri ; Schoonjans, Kristina ; Suzuki, Tatsuya ; Itoh, Hiroshi ; Auwerx, Johan

    PLOS ONE 7 ( 8 )  2012.08

    Joint Work, Accepted

  • TGR5 potentiates GLP-1 secretion in response to anionic exchange resins.

    Watanabe Mitsuhiro

    Nature. Sci Rep. 2   430 2012

    Joint Work, Accepted

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Papers, etc., Registered in KOARA 【 Display / hide

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Reviews, Commentaries, etc. 【 Display / hide

  • 臓器間ネットワークと糖尿病 胆汁酸によるエネルギー代謝調節機構

    Watanabe Mitsuhiro

    DiabetesFrontier 25 ( 1 ) 63 - 71 2014.02

    Introduction and explanation (scientific journal), Joint Work

Research Projects of Competitive Funds, etc. 【 Display / hide

  • 胆汁酸-腸内細菌-生体シグナル伝達相互作用解明による生活習慣病個別化医療の推進

    2016.04
    -
    2019.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 渡辺 光博, Grant-in-Aid for Scientific Research (B), Principal Investigator

 

Courses Taught 【 Display / hide

  • WORKSHOP ON MOLECULAR HEALTH SCIENCE

    2019

  • SEMINAR B

    2019

  • MOLECULAR NUTRITIONAL SCIENCE FOR HEALTH

    2019

  • MASTER SEMINAR

    2019

  • INTRODUCTION TO INTEGRATED HEALTH RESEARCH

    2019

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Courses Previously Taught 【 Display / hide

  • 代謝の基礎生物学

    Keio University, 2015, Spring Semester

  • リーダーシップ開発のためのコーチング

    Keio University, 2015, Spring Semester